Lipid-Sorting Specificity Encoded in K-Ras Membrane Anchor Regulates Signal Output

Cell

Volumn 168, Issue 1-2, 2017, Pages 239-251.e16

  Zhou, Yong ^a   Prakash, Priyanka ^a   Liang, Hong ^a   Cho, Kwang Jin ^a   Gorfe, Alemayehu A ^a   Hancock, John F ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

electron microscopy; K RAS; molecular dynamics; nanoclustering; phosphatidylserine; polybasic domain

Indexed keywords

ARGININE; K RAS PROTEIN; LIPID; LYSINE; PRENYLAMINE; KRAS PROTEIN, HUMAN; NEOPRENE; PROTEIN P21;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; INTRACELLULAR SIGNALING; LIPID COMPOSITION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; STATIC ELECTRICITY; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR MODEL; MUTATION;

CELL MEMBRANE; HUMANS; LIPIDS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION; NEOPRENE; PROTEIN DOMAINS; PROTO-ONCOGENE PROTEINS P21(RAS);

EID: 85009164725     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.11.059     Document Type: Article

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