Inactivation of maternal Hif-1α at mid-pregnancy causes placental defects and deficits in oxygen delivery to the fetal organs under hypoxic stress

Developmental Biology

Volumn 422, Issue 2, 2017, Pages 171-185

  Kenchegowda, Doreswamy ^a   Natale, Bryony ^b   Lemus, Maria A ^b   Natale, David R ^b   Fisher, Steven A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Feto placental unit; Trophoblast; Uterine natural killer cells

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN; OXYGEN; TAMOXIFEN; HIF1A PROTEIN, MOUSE; PLACENTA PROTEIN; TPBPA PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; CELL PROLIFERATION; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DECIDUA; EPICARDIUM; FEMALE; FETUS; FETUS DEVELOPMENT; FETUS TISSUE; GENE INACTIVATION; GENE SILENCING; GESTATIONAL AGE; HEART; HETEROZYGOTE; HIF 1A GENE; HYPOXIA; INNER EAR; INNER EAR MALFORMATION; LIVER; LUCIFERASE ASSAY; MESENCHYME; MOUSE; NATURAL KILLER CELL; NONHUMAN; OXYGEN TRANSPORT; PLACENTA DEVELOPMENT; PLACENTA DISORDER; PREGNANCY; TROPHOBLAST; TUNEL ASSAY; ABNORMALITIES; ANIMAL; CELL HYPOXIA; CYTOLOGY; EMBRYOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PLACENTA; REPRODUCTION;

ANIMALS; APOPTOSIS; CELL HYPOXIA; CELL PROLIFERATION; FEMALE; HEART; HEART DEFECTS, CONGENITAL; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IN SITU NICK-END LABELING; KILLER CELLS, NATURAL; MICE; OXYGEN; PLACENTA; PLACENTATION; PREGNANCY; PREGNANCY PROTEINS; TROPHOBLASTS;

EID: 85008487828     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2016.12.013     Document Type: Article

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