Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury

Journal of Clinical Investigation

Volumn 127, Issue 1, 2017, Pages 321-334

  Leaf, Irina A ^a,b   Nakagawa, Shunsaku ^c   Johnson, Bryce G ^a,c   Cha, Jin Joo ^c   Mittelsteadt, Kristen ^c   Guckian, Kevin M ^a   Gomez, Ivan G ^a,c   Altemeier, William A ^c   Duffield, Jeremy S ^a,c  

^a BIOGEN   (United States)

^b SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 18; INTERLEUKIN 1BETA; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN SERINE THREONINE KINASE INHIBITOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; IL1B PROTEIN, HUMAN; IL1B PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK4 PROTEIN, HUMAN; IRAK4 PROTEIN, MOUSE; MYD88 PROTEIN, HUMAN; MYD88 PROTEIN, MOUSE;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME PHOSPHORYLATION; EXTRACELLULAR MATRIX; FEMALE; FIBROGENESIS; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PERICYTE; PRIORITY JOURNAL; STROMA CELL; TISSUE INJURY; ANIMAL; CELL CULTURE; FIBROSIS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ACUTE KIDNEY INJURY; ANIMALS; CELLS, CULTURED; FIBROSIS; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-1BETA; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; MYOFIBROBLASTS; PERICYTES; SIGNAL TRANSDUCTION;

EID: 85008354898     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI87532     Document Type: Article

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