메뉴 건너뛰기




Volumn 15, Issue 12, 2016, Pages 2894-2904

Antitumor and antiangiogenic effects of aspirin-PC in ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID DERIVATIVE; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; ASPIRIN PHOSPHATIDYLCHOLINE; B 20; BEVACIZUMAB; CASPASE 3; KI 67 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VASCULOTROPIN INHIBITOR; ASPIRIN-PHOSPHATIDYLCHOLINE; BIOLOGICAL MARKER; PHOSPHATIDYLCHOLINE; THROMBOXANE; THROMBOXANE B3;

EID: 85008312083     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-16-0074     Document Type: Article
Times cited : (43)

References (50)
  • 1
    • 84922532328 scopus 로고    scopus 로고
    • Estimates of benefits and harms of prophylactic use of aspirin in the general population
    • Cuzick J, Thorat MA, Bosetti C, Brown PH, Burn J, Cook NR, et al. Estimates of benefits and harms of prophylactic use of aspirin in the general population. Ann Oncol 2015;26:47-57.
    • (2015) Ann Oncol , vol.26 , pp. 47-57
    • Cuzick, J.1    Thorat, M.A.2    Bosetti, C.3    Brown, P.H.4    Burn, J.5    Cook, N.R.6
  • 4
    • 84863412124 scopus 로고    scopus 로고
    • Short-Term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: Analysis of the time course of risks and benefits in 51 randomised controlled trials
    • Rothwell PM, Price JF, Fowkes FG, Zanchetti A, Roncaglioni MC, Tognoni G, et al. Short-Term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: Analysis of the time course of risks and benefits in 51 randomised controlled trials. Lancet 2012;379:1602-12.
    • (2012) Lancet , vol.379 , pp. 1602-1612
    • Rothwell, P.M.1    Price, J.F.2    Fowkes, F.G.3    Zanchetti, A.4    Roncaglioni, M.C.5    Tognoni, G.6
  • 5
    • 84863399038 scopus 로고    scopus 로고
    • Effect of daily aspirin on risk of cancer metastasis: A study of incident cancers during randomised controlled trials
    • Rothwell PM, Wilson M, Price JF, Belch JF, Meade TW, Mehta Z. Effect of daily aspirin on risk of cancer metastasis: A study of incident cancers during randomised controlled trials. Lancet 2012;379: 1591-601.
    • (2012) Lancet , vol.379 , pp. 1591-1601
    • Rothwell, P.M.1    Wilson, M.2    Price, J.F.3    Belch, J.F.4    Meade, T.W.5    Mehta, Z.6
  • 6
    • 43049138015 scopus 로고    scopus 로고
    • Improved survival time: What can survival cure models tell us about population-based survival improvements in late-stage colorectal ovarian, and testicular cancer?
    • Huang L, Cronin KA, Johnson KA, Mariotto AB, Feuer EJ. Improved survival time: What can survival cure models tell us about population-based survival improvements in late-stage colorectal, ovarian, and testicular cancer? Cancer 2008;112:2289-300.
    • (2008) Cancer , vol.112 , pp. 2289-2300
    • Huang, L.1    Cronin, K.A.2    Johnson, K.A.3    Mariotto, A.B.4    Feuer, E.J.5
  • 9
    • 84893873955 scopus 로고    scopus 로고
    • Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: A pooled analysis in the Ovarian Cancer Association Consortium
    • djt431
    • Trabert B, Ness RB, Lo-Ciganic WH, Murphy MA, Goode EL, Poole EM, et al. Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: A pooled analysis in the Ovarian Cancer Association Consortium. J Natl Cancer Inst 2014; 106:djt431.
    • (2014) J Natl Cancer Inst , vol.106
    • Trabert, B.1    Ness, R.B.2    Lo-Ciganic, W.H.3    Murphy, M.A.4    Goode, E.L.5    Poole, E.M.6
  • 11
    • 84871137478 scopus 로고    scopus 로고
    • Meta-Analysis on the association between non-steroidal anti-inflammatory drug use and ovarian cancer
    • Ni X, Ma J, Zhao Y, Wang Y, Wang S. Meta-Analysis on the association between non-steroidal anti-inflammatory drug use and ovarian cancer. Br J Clin Pharmacol 2013;75:26-35.
    • (2013) Br J Clin Pharmacol , vol.75 , pp. 26-35
    • Ni, X.1    Ma, J.2    Zhao, Y.3    Wang, Y.4    Wang, S.5
  • 12
    • 84905225509 scopus 로고    scopus 로고
    • Aspirin use and survival after the diagnosis of breast cancer: A population-based cohort study
    • Fraser DM, Sullivan FM, Thompson AM, McCowan C. Aspirin use and survival after the diagnosis of breast cancer: A population-based cohort study. Br J Cancer 2014;111:623-7.
    • (2014) Br J Cancer , vol.111 , pp. 623-627
    • Fraser, D.M.1    Sullivan, F.M.2    Thompson, A.M.3    McCowan, C.4
  • 13
    • 46049093776 scopus 로고    scopus 로고
    • Gastric mucosal defense and cytoprotection: Bench to bedside
    • Laine L, Takeuchi K, Tarnawski A. Gastric mucosal defense and cytoprotection: Bench to bedside. Gastroenterology 2008;135:41-60.
    • (2008) Gastroenterology , vol.135 , pp. 41-60
    • Laine, L.1    Takeuchi, K.2    Tarnawski, A.3
  • 14
    • 84876672676 scopus 로고    scopus 로고
    • Role of phospholipids in protection of the GI mucosa
    • Lichtenberger LM. Role of phospholipids in protection of the GI mucosa. Dig Dis Sci 2013;58:891-3.
    • (2013) Dig Dis Sci , vol.58 , pp. 891-893
    • Lichtenberger, L.M.1
  • 15
    • 0028915433 scopus 로고
    • The hydrophobic barrier properties of gastrointestinal mucus
    • Lichtenberger LM. The hydrophobic barrier properties of gastrointestinal mucus. Annu Rev Physiol 1995;57:565-83.
    • (1995) Annu Rev Physiol , vol.57 , pp. 565-583
    • Lichtenberger, L.M.1
  • 16
    • 0028939954 scopus 로고
    • Non-steroidal anti-inflammatory drugs (NSAIDs) associate with zwitterionic phospholipids: Insight into the mechanism and reversal of NSAID-induced gastrointestinal injury
    • Lichtenberger LM, Wang ZM, Romero JJ, Ulloa C, Perez JC, Giraud MN, et al. Non-steroidal anti-inflammatory drugs (NSAIDs) associate with zwitterionic phospholipids: Insight into the mechanism and reversal of NSAID-induced gastrointestinal injury. Nat Med 1995;1:154-8.
    • (1995) Nat Med , vol.1 , pp. 154-158
    • Lichtenberger, L.M.1    Wang, Z.M.2    Romero, J.J.3    Ulloa, C.4    Perez, J.C.5    Giraud, M.N.6
  • 17
    • 84860820855 scopus 로고    scopus 로고
    • Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: Characterization of interaction of NSAIDs with phosphatidylcholine
    • Lichtenberger LM, Zhou Y, Jayaraman V, Doyen JR, O'Neil RG, Dial EJ, et al. Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: Characterization of interaction of NSAIDs with phosphatidylcholine. Biochim Biophys Acta 2012;1821:994-1002.
    • (2012) Biochim Biophys Acta , vol.1821 , pp. 994-1002
    • Lichtenberger, L.M.1    Zhou, Y.2    Jayaraman, V.3    Doyen, J.R.4    O'Neil, R.G.5    Dial, E.J.6
  • 18
    • 77949413862 scopus 로고    scopus 로고
    • Association of phosphatidylcholine and NSAIDs as a novel strategy to reduce gastrointestinal toxicity
    • Lichtenberger LM, Barron M, Marathi U. Association of phosphatidylcholine and NSAIDs as a novel strategy to reduce gastrointestinal toxicity. Drugs Today (Barc) 2009;45:877-90.
    • (2009) Drugs Today (Barc , vol.45 , pp. 877-890
    • Lichtenberger, L.M.1    Barron, M.2    Marathi, U.3
  • 19
    • 34047226649 scopus 로고    scopus 로고
    • Surface phospholipids in gastric injury and protection when a selective cyclooxygenase-2 inhibitor (Coxib) is used in combination with aspirin
    • Lichtenberger LM, Romero JJ, Dial EJ. Surface phospholipids in gastric injury and protection when a selective cyclooxygenase-2 inhibitor (Coxib) is used in combination with aspirin. Br J Pharmacol 2007;150:913-9.
    • (2007) Br J Pharmacol , vol.150 , pp. 913-919
    • Lichtenberger, L.M.1    Romero, J.J.2    Dial, E.J.3
  • 20
    • 84875092945 scopus 로고    scopus 로고
    • Advent of novel phosphatidylcholineassociated nonsteroidal anti-inflammatory drugs with improved gastrointestinal safety
    • Lim YJ, Dial EJ, Lichtenberger LM. Advent of novel phosphatidylcholineassociated nonsteroidal anti-inflammatory drugs with improved gastrointestinal safety. Gut Liver 2013;7:7-15.
    • (2013) Gut Liver , vol.7 , pp. 7-15
    • Lim, Y.J.1    Dial, E.J.2    Lichtenberger, L.M.3
  • 21
    • 79751528169 scopus 로고    scopus 로고
    • Lowdose aspirin-induced ulceration is attenuated by aspirin-phosphatidylcholine: A randomized clinical trial
    • Cryer B, Bhatt DL, Lanza FL, Dong JF, Lichtenberger LM, Marathi UK. Lowdose aspirin-induced ulceration is attenuated by aspirin-phosphatidylcholine: A randomized clinical trial. Am J Gastroenterol 2011;106:272-7.
    • (2011) Am J Gastroenterol , vol.106 , pp. 272-277
    • Cryer, B.1    Bhatt, D.L.2    Lanza, F.L.3    Dong, J.F.4    Lichtenberger, L.M.5    Marathi, U.K.6
  • 22
    • 47749083511 scopus 로고    scopus 로고
    • Clinical trial: Comparison of ibuprofen-phosphatidylcholine and ibuprofen on the gastrointestinal safety and analgesic efficacy in osteoarthritic patients
    • Lanza FL, Marathi UK, Anand BS, Lichtenberger LM. Clinical trial: Comparison of ibuprofen-phosphatidylcholine and ibuprofen on the gastrointestinal safety and analgesic efficacy in osteoarthritic patients. Aliment Pharmacol Ther 2008;28:431-42.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 431-442
    • Lanza, F.L.1    Marathi, U.K.2    Anand, B.S.3    Lichtenberger, L.M.4
  • 23
    • 33644839489 scopus 로고    scopus 로고
    • Phosphatidylcholine-Associated nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit DNA synthesis and the growth of colon cancer cells in vitro
    • Dial EJ, Doyen JR, Lichtenberger LM. Phosphatidylcholine-Associated nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit DNA synthesis and the growth of colon cancer cells in vitro.Cancer Chemother Pharmacol 2006;57:295-300.
    • (2006) Cancer Chemother Pharmacol , vol.57 , pp. 295-300
    • Dial, E.J.1    Doyen, J.R.2    Lichtenberger, L.M.3
  • 26
    • 73949104695 scopus 로고    scopus 로고
    • Combined anti-Angiogenic therapy against VEGF and integrin alphaVbeta3 in an orthotopic model of ovarian cancer
    • Kim TJ, Landen CN, Lin YG, Mangala LS, Lu C, Nick AM, et al. Combined anti-Angiogenic therapy against VEGF and integrin alphaVbeta3 in an orthotopic model of ovarian cancer. Cancer Biol Ther 2009;8:2263-72.
    • (2009) Cancer Biol Ther , vol.8 , pp. 2263-2272
    • Kim, T.J.1    Landen, C.N.2    Lin, Y.G.3    Mangala, L.S.4    Lu, C.5    Nick, A.M.6
  • 28
    • 84898753092 scopus 로고    scopus 로고
    • Cross-Talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib
    • Huang J, HuW, Bottsford-Miller J, Liu T, Han HD, Zand B, et al. Cross-Talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib. Clin Cancer Res 2014;20:1846-55.
    • (2014) Clin Cancer Res , vol.20 , pp. 1846-1855
    • Huang, J.1    Huw Bottsford-Miller, J.2    Liu, T.3    Han, H.D.4    Zand, B.5
  • 29
    • 55249107979 scopus 로고    scopus 로고
    • Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma
    • Tanaka N, Kato H, Inose T, Kimura H, Faried A, Sohda M, et al. Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma. Br J Cancer 2008;99:1468-75.
    • (2008) Br J Cancer , vol.99 , pp. 1468-1475
    • Tanaka, N.1    Kato, H.2    Inose, T.3    Kimura, H.4    Faried, A.5    Sohda, M.6
  • 30
    • 0034971407 scopus 로고    scopus 로고
    • Phosphatidylcholine association increases the anti-inflammatory and analgesic activity of ibuprofen in acute and chronic rodent models of joint inflammation: Relationship to alterations in bioavailability and cyclooxygenase-inhibitory potency
    • Lichtenberger LM, Romero JJ, de Ruijter WM, Behbod F, Darling R, Ashraf AQ, et al. Phosphatidylcholine association increases the anti-inflammatory and analgesic activity of ibuprofen in acute and chronic rodent models of joint inflammation: Relationship to alterations in bioavailability and cyclooxygenase-inhibitory potency. J Pharmacol Exp Ther 2001;298: 279-87.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 279-287
    • Lichtenberger, L.M.1    Romero, J.J.2    De Ruijter, W.M.3    Behbod, F.4    Darling, R.5    Ashraf, A.Q.6
  • 32
    • 65349152488 scopus 로고    scopus 로고
    • Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: An international consensus statement
    • Cuzick J, Otto F, Baron JA, Brown PH, Burn J, Greenwald P, et al. Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: An international consensus statement. Lancet Oncol 2009;10:501-7.
    • (2009) Lancet Oncol , vol.10 , pp. 501-507
    • Cuzick, J.1    Otto, F.2    Baron, J.A.3    Brown, P.H.4    Burn, J.5    Greenwald, P.6
  • 33
    • 77957733526 scopus 로고    scopus 로고
    • Should nonsteroidal anti-inflammatory drugs (NSAIDs) be prescribed to the older adult?
    • Barkin RL, Beckerman M, Blum SL, Clark FM, Koh EK, Wu DS. Should nonsteroidal anti-inflammatory drugs (NSAIDs) be prescribed to the older adult? Drugs Aging 2010;27:775-89.
    • (2010) Drugs Aging , vol.27 , pp. 775-789
    • Barkin, R.L.1    Beckerman, M.2    Blum, S.L.3    Clark, F.M.4    Koh, E.K.5    Wu, D.S.6
  • 34
    • 0031042347 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and gastroenteropathy: The second hundred years
    • Wallace JL. Nonsteroidal anti-inflammatory drugs and gastroenteropathy: The second hundred years. Gastroenterology 1997;112:1000-16.
    • (1997) Gastroenterology , vol.112 , pp. 1000-1016
    • Wallace, J.L.1
  • 35
    • 0033577982 scopus 로고    scopus 로고
    • Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs
    • Wolfe MM, Lichtenstein DR, Singh G. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N Engl J Med 1999;340:1888-99.
    • (1999) N Engl J Med , vol.340 , pp. 1888-1899
    • Wolfe, M.M.1    Lichtenstein, D.R.2    Singh, G.3
  • 36
    • 0030440981 scopus 로고    scopus 로고
    • Zwitterionic phospholipids enhance aspirin's therapeutic activity, as demonstrated in rodent model systems
    • Lichtenberger LM, Ulloa C, Vanous AL, Romero JJ, Dial EJ, Illich PA, et al. Zwitterionic phospholipids enhance aspirin's therapeutic activity, as demonstrated in rodent model systems. J Pharmacol Exp Ther 1996;277:1221-7.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1221-1227
    • Lichtenberger, L.M.1    Ulloa, C.2    Vanous, A.L.3    Romero, J.J.4    Dial, E.J.5    Illich, P.A.6
  • 37
    • 33646256589 scopus 로고    scopus 로고
    • The impact of low-dose aspirin on endoscopic gastric and duodenal ulcer rates in users of a non-selective non-steroidal anti-inflammatory drug or a cyclo-oxygenase-2-selective inhibitor
    • Goldstein JL, Lowry SC, Lanza FL, Schwartz HI, Dodge WE. The impact of low-dose aspirin on endoscopic gastric and duodenal ulcer rates in users of a non-selective non-steroidal anti-inflammatory drug or a cyclo-oxygenase-2-selective inhibitor. Aliment Pharmacol Ther 2006;23:1489-98.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1489-1498
    • Goldstein, J.L.1    Lowry, S.C.2    Lanza, F.L.3    Schwartz, H.I.4    Dodge, W.E.5
  • 40
    • 6044274282 scopus 로고    scopus 로고
    • Coxibs and cardiovascular disease
    • Fitzgerald GA. Coxibs and cardiovascular disease. N Engl J Med 2004; 351:1709-11.
    • (2004) N Engl J Med , vol.351 , pp. 1709-1711
    • Fitzgerald, G.A.1
  • 41
    • 33644870565 scopus 로고    scopus 로고
    • COX isoforms in the cardiovascular system: Understanding the activities of non-steroidal anti-inflammatory drugs
    • Mitchell JA, Warner TD. COX isoforms in the cardiovascular system: Understanding the activities of non-steroidal anti-inflammatory drugs. Nat Rev Drug Discov 2006;5:75-86.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 75-86
    • Mitchell, J.A.1    Warner, T.D.2
  • 42
    • 34047105383 scopus 로고    scopus 로고
    • NSAIDs and cancer prevention: Targets downstream of COX-2
    • Cha YI, DuBois RN. NSAIDs and cancer prevention: Targets downstream of COX-2. Annu Rev Med 2007;58:239-52.
    • (2007) Annu Rev Med , vol.58 , pp. 239-252
    • Cha, Y.I.1    DuBois, R.N.2
  • 43
    • 0037374468 scopus 로고    scopus 로고
    • Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer
    • Gupta RA, Tejada LV, Tong BJ, Das SK, Morrow JD, Dey SK, et al. Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. Cancer Res 2003;63:906-11.
    • (2003) Cancer Res , vol.63 , pp. 906-911
    • Gupta, R.A.1    Tejada, L.V.2    Tong, B.J.3    Das, S.K.4    Morrow, J.D.5    Dey, S.K.6
  • 44
    • 18144370769 scopus 로고    scopus 로고
    • Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer
    • Daikoku T, Wang D, Tranguch S, Morrow JD, Orsulic S, DuBois RN, et al. Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. Cancer Res 2005;65:3735-44.
    • (2005) Cancer Res , vol.65 , pp. 3735-3744
    • Daikoku, T.1    Wang, D.2    Tranguch, S.3    Morrow, J.D.4    Orsulic, S.5    DuBois, R.N.6
  • 45
    • 84885462303 scopus 로고    scopus 로고
    • Aspirin blocks EGF-stimulated cell viability in a COX-1 dependent manner in ovarian cancer cells
    • Cho M, Kabir SM, Dong Y, Lee E, Rice VM, Khabele D, et al. Aspirin blocks EGF-stimulated cell viability in a COX-1 dependent manner in ovarian cancer cells. J Cancer 2013;4:671-8.
    • (2013) J Cancer , vol.4 , pp. 671-678
    • Cho, M.1    Kabir, S.M.2    Dong, Y.3    Lee, E.4    Rice, V.M.5    Khabele, D.6
  • 46
    • 62549099521 scopus 로고    scopus 로고
    • Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats
    • Kapetanovic IM, Bauer KS, Tessier DM, Lindeblad MO, Zakharov AD, Lubet R, et al. Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats. Chem Biol Interact 2009;179:233-9.
    • (2009) Chem Biol Interact , vol.179 , pp. 233-239
    • Kapetanovic, I.M.1    Bauer, K.S.2    Tessier, D.M.3    Lindeblad, M.O.4    Zakharov, A.D.5    Lubet, R.6
  • 47
    • 0028044609 scopus 로고
    • Towards a better aspirin
    • Vane J. Towards a better aspirin. Nature 1994;367:215-6.
    • (1994) Nature , vol.367 , pp. 215-216
    • Vane, J.1
  • 48
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as amechanism of action for aspirin-like drugs
    • Vane JR. Inhibition of prostaglandin synthesis as amechanism of action for aspirin-like drugs. Nat New Biol 1971;231:232-5.
    • (1971) Nat New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.