Charting Biologically Relevant Spirocyclic Compound Space

Chemistry - A European Journal

Volumn 23, Issue 3, 2017, Pages 703-710

  Müller, Gerhard ^a   Berkenbosch, Tim ^a   Benningshof, Jorg C J ^a   Stumpfe, Dagmar ^b   Bajorath, Jürgen ^b  

^a Mercachem BV   (Netherlands)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

compound distribution; computational analysis; scaffold synthesis; spiro compounds; structural biology

Indexed keywords

DRUG PRODUCTS;

COMPOUND DISTRIBUTIONS; COMPUTATIONAL ANALYSIS; CORRESPONDING COMPOUNDS; G-PROTEIN COUPLED RECEPTORS; NATURAL PRODUCTS; PHARMACEUTICAL RESEARCH; SPIRO COMPOUNDS; STRUCTURAL BIOLOGY;

SCAFFOLDS (BIOLOGY);

BIOLOGICAL PRODUCT; G PROTEIN COUPLED RECEPTOR; PEPTIDE HYDROLASE; SPIRO COMPOUND;

ANTAGONISTS AND INHIBITORS; CHEMICAL DATABASE; CHEMISTRY; CONFORMATION; DRUG DEVELOPMENT; METABOLISM; SYNTHESIS;

BIOLOGICAL PRODUCTS; DATABASES, CHEMICAL; DRUG DISCOVERY; MOLECULAR CONFORMATION; PEPTIDE HYDROLASES; RECEPTORS, G-PROTEIN-COUPLED; SPIRO COMPOUNDS;

EID: 85008264712     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201604714     Document Type: Article

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