Biology-oriented synthesis: Harnessing the power of evolution

Journal of the American Chemical Society

Volumn 136, Issue 34, 2014, Pages 11853-11859

  Van Hattum, Hilde ^a   Waldmann, Herbert ^a,b  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b TU DORTMUND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; LIGANDS; MOLECULES; PROTEINS; SYNTHESIS (CHEMICAL);

BIOLOGICAL RESEARCH; CHEMICAL BIOLOGY; COMPOUND LIBRARIES; GUIDING PRINCIPLES; NATURAL PRODUCTS; NATURALLY OCCURRING; PROTEIN ACTIVITY; SMALL MOLECULES;

BIOLOGY;

NATURAL PRODUCT; PROTEIN; BIOLOGICAL PRODUCT; MOLECULAR LIBRARY;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BIOLOGICAL ACTIVITY; BIOLOGY; BIOLOGY ORIENTED SYNTHESIS; BIOSYNTHESIS; CENTROSOME; COMBINATORIAL LIBRARY; CYCLOADDITION; DRUG DEVELOPMENT; ENANTIOSELECTIVITY; EVOLUTION; MEDICINAL CHEMISTRY; MITOSIS SPINDLE; NERVE CELL NETWORK; NERVE FIBER GROWTH; NONHUMAN; PROTEIN STRUCTURE; SPINDLE POLE; SYNTHESIS; SYSTEMS BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR LIBRARY; PROTEIN CONFORMATION; PROTEIN SYNTHESIS; COMPUTER PROGRAM; MOLECULE;

BIOLOGICAL PRODUCTS; DRUG DISCOVERY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; PROTEINS; SMALL MOLECULE LIBRARIES;

EID: 84906766592     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja505861d     Document Type: Article

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