Phenethyl isothiocyanate suppresses the metastasis of ovarian cancer associated with the inhibition of CRM1-mediated nuclear export and mTOR-STAT3 pathway

Cancer Biology and Therapy

Volumn 18, Issue 1, 2017, Pages 26-35

  Shao, Wen Yu ^a   Yang, Yong Liang ^b   Yan, Huan ^c   Huang, Qian ^a   Liu, Kai Jiang ^c   Zhang, Shu ^c  

^a XINJIANG MEDICAL UNIVERSITY   (China)

^b DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

CRM1; metastasis; mTOR; nuclear export; ovarian cancer; PEITC; STAT3

Indexed keywords

EXPORTIN 1; GELATINASE A; GELATINASE B; MAMMALIAN TARGET OF RAPAMYCIN; PHENETHYL ISOTHIOCYANATE; STAT3 PROTEIN; ANTINEOPLASTIC AGENT; CELL RECEPTOR; EXPORTIN 1 PROTEIN; ISOTHIOCYANIC ACID DERIVATIVE; KARYOPHERIN; MTOR PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASCITES FLUID CYTOLOGY; CANCER CELL LINE; CANCER SURVIVAL; CANCER TISSUE; CELL INVASION; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; IC50; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MIDDLE AGED; MOUSE; NONHUMAN; OVARY CARCINOMA; OVARY METASTASIS; OVERALL SURVIVAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; METABOLISM; METASTASIS; NUCLEOCYTOPLASMIC TRANSPORT; OVARIAN NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTICARCINOGENIC AGENTS; CELL LINE, TUMOR; FEMALE; HUMANS; ISOTHIOCYANATES; KARYOPHERINS; MICE; MIDDLE AGED; NEOPLASM METASTASIS; OVARIAN NEOPLASMS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STAT3 TRANSCRIPTION FACTOR; TOR SERINE-THREONINE KINASES;

EID: 85008182712     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.1080/15384047.2016.1264540     Document Type: Article

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