Immunosuppressive CD14+HLA-DRlo/neg monocytes are elevated in pancreatic cancer and “primed” by tumor-derived exosomes

OncoImmunology

Volumn 6, Issue 1, 2017, Pages

  Javeed, Naureen ^a   Gustafson, Michael P ^b   Dutta, Shamit K ^a   Lin, Yi ^b   Bamlet, William R ^b   Oberg, Ann L ^b   Petersen, Gloria M ^b   Chari, Suresh T ^b   Dietz, Allan B ^b   Mukhopadhyay, Debabrata ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Exosomes; HLA DR; Immune profiling; Immunosuppression; Monocytes; Pancreatic cancer

Indexed keywords

ARGINASE; CD14 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; IMMUNOSUPPRESSIVE AGENT; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN;

ADULT; AGED; ARTICLE; CELL POPULATION; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; EXOSOME; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOPHENOTYPING; IMMUNOSUPPRESSIVE TREATMENT; INTERNALIZATION; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MEMBRANE MICROPARTICLE; MIDDLE AGED; MONOCYTE; NATURAL KILLER CELL; PANCREAS CANCER; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TUMOR DERIVED EXOSOME; WESTERN BLOTTING;

EID: 85007318951     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2016.1252013     Document Type: Article

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