Role of LncRNA-activated by transforming growth factor beta in the progression of hepatitis C virus-related liver fibrosis

Discovery Medicine

Volumn 22, Issue 119, 2016, Pages

  Fu, Na ^a   Niu, Xuemin ^a   Wang, Yang ^a   Du, Huijuan ^a   Wang, Baoyu ^a   Du, Jinghua ^a   Li, Ya ^a   Wang, Rongqi ^a   Zhang, Yuguo ^a   Zhao, Suxian ^a   Sun, Dianxing ^b   Qiao, Liang ^c   Nan, Yuemin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b BETHUNE INTERNATIONAL PEACE HOSPITAL   (China)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CHOLECYSTOKININ OCTAPEPTIDE; COLLAGEN TYPE 1; LONG UNTRANSLATED RNA; MICRORNA; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; LONG NONCODLNG RNA ATB, HUMAN;

ADULT; ARTICLE; CELL PROLIFERATION ASSAY; CLINICAL ARTICLE; COMPETITIVE BINDING ASSAY; CONTROLLED STUDY; DRUG TARGETING; FEMALE; FIBROGENESIS; GENETIC TRANSFECTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIVER BIOPSY; LIVER FIBROSIS; LUCIFERASE ASSAY; MALE; MIDDLE AGED; PROTEIN EXPRESSION; RADIOIMMUNOPRECIPITATION; REAL TIME POLYMERASE CHAIN REACTION; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SEROLOGY; UPREGULATION; VIRUS INFECTION; WESTERN BLOTTING; CELL LINE; CELL PROLIFERATION; GENETICS; HEK293 CELL LINE; HEPACIVIRUS; LIVER CIRRHOSIS; METABOLISM; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

ADULT; BLOTTING, WESTERN; CELL LINE; CELL PROLIFERATION; FEMALE; HEK293 CELLS; HEPACIVIRUS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIVER CIRRHOSIS; MALE; MICRORNAS; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RNA, LONG NONCODING;

EID: 85007318857     PISSN: 15396509     EISSN: 19447930     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Bandyopadhyay S, Friedman RC, Marquez RT, Keck K, Kong B, Icardi MS, Brown KE, Burge CB, Schmidt WN, Wang Y, Mccaffrey AP. Hepatitis C virus infection and hepatic stellate cell activation downregulate miR-29: miR-29 overexpression reduces hepatitis C viral abundance in culture. J Infect Dis 203(12):1753-1762, 2011.
2. Batista PJ, Chang HY. Long noncoding RNAs: cellular address codes in development and disease. Cell 152(6):1298-1307, 2013.
3. Bedossa P, Poynard T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 24(2):289-293, 1996.
4. Fassio E. Hepatitis C and hepatocellular carcinoma. Ann Hepatol 9 (Suppl):119-122, 2010.
5. George J, Roulot D, Koteliansky V, Bissell D. In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci U S A. 96(22):12719-12724, 1999.
6. He Y, Wu YT, Huang C, Meng XM, Ma TT, Wu BM, Xu FY, Zhang L, Lv XW, Li J. Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis. Biochim Biophys Acta 1842(11):2204-2215, 2014.
7. Iguchi T, Uchi R, Nambara S, Saito T, Komatsu H, Hirata H, Ueda M, Sakimura S, Takano Y, Kurashige J, Shinden Y, Eguchi H, Sugimachi K, Maehara Y, Mimori K. A Long Noncoding RNA, lncRNA-ATB, Is Involved in theProgression and Prognosis of Colorectal Cancer. Anticancer Res 35(3):1385-1388, 2015.
8. Jahan S, Ashfaq UA, Khaliq S, Samreen B, Afzal N. Dual behavior of HCV Core gene in regulation of apoptosis is important in progression of HCC. Infect Genet Evol 12(2):236-239, 2012.
9. Lakner AM, Steuerwald NM, Walling TL, Ghosh S, Li T, Mckillop IH, Russo MW, Bonkovsky HL, Schrum LW. Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis. Hepatology 56(1):300-310, 2012.
10. Lee JT. Epigenetic regulation by long noncoding RNAs. Science 338(6113):1435-1439, 2012.
11. Ma J, Liu J, Wang Z, Gu X, Fan Y, Zhang W, Xu L, Zhang J, Cai D. NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1beta induction. Mol Cancer 13:40, 2014.
12. Nagano T, Fraser P. No-nonsense functions for long noncoding RNAs. Cell 145(2):178-181, 2011.
13. Piersma B, Bank RA, Boersema M. Signaling in Fibrosis: TGF-beta, WNT, and YAP/TAZ Converge. Front Med (Lausanne) 2:59, 2015.
14. Ponting CP, Oliver PL, Reik W. Evolution and functions of long noncoding RNAs. Cell 136(4):629-641, 2009.
15. Qu S, Yang X, Song W, Sun W, Li X, Wang J, Zhong Y, Shang R, Ruan B, Zhang Z, Zhang X, Li H. Downregulation of lncRNA-ATB correlates with clinical progression and unfavorable prognosis in pancreatic cancer. Tumour Biol 37(3):3933-3938, 2016.
16. Quagliata L, Terracciano LM. Liver Diseases and Long Non-Coding RNAs: New Insight and Perspective. Front Med (Lausanne) 1:35, 2014.
17. Saito T, Kurashige J, Nambara S, Komatsu H, Hirata H, Ueda M, Sakimura S, Uchi R, Takano Y, Shinden Y, Iguchi T, Eguchi H, Ehata S, Murakami K, Sugimachi K, Mimori K. A Long Non-coding RNA Activated by Transforming Growth Factor-beta is an Independent Prognostic Marker of Gastric Cancer. Ann Surg Oncol 22(Suppl 3):915-922, 2015.
18. Sakai K, Jawaid S, Sasaki T, Bou-Gharios G, Sakai T. Transforming growth factor-beta-independent role of connective tissue growth factor in the development of liver fibrosis. Am J Pathol 184(10):2611-2617, 2014.
19. Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell 146(3):353-358, 2011.
20. Shi S, Wang L, Yu B, Li Y, Jin Y, Bai X. LncRNA-ATB promotes trastuzumab resistance and invasion-metastasis cascade in breast cancer. Oncotarget 6(13):11652-11663, 2015.
21. Shimada H, Staten NR, Rajagopalan LE. TGF-beta1 mediated activation of Rho kinase induces TGF-beta2 and endothelin-1 expression in human hepatic stellate cells. J Hepatol 54(3):521-528, 2011.
22. Sysa P, Potter J, Liu X, Mezey E. Transforming growth factor-beta1 up-regulation of human alpha(1)(I) collagen is mediated by Sp1 and Smad2 transacting factors. DNA Cell Biol 28(9):425-434, 2009.
23. Wang Y, Li J, Wang X, Sang M, Ho W. Hepatic stellate cells, liver innate immunity, and hepatitis C virus. J Gastroenterol Hepatol 28 (Suppl 1):112-115, 2013.
24. Wang Y, Mao S, He Q, Zi Y, Wen J, Feng D. Specific activation of 2'-5'oligoadenylate synthetase gene promoter by hepatitis C virus-core protein: A potential for developing hepatitis C virus targeting gene therapy. World J Gastroenterol 15(25):3178-3182, 2009.
25. WHO. Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection. Geneva, 2014.
26. Xiong Y, Jia M, Yuan J, Zhang C, Zhu Y, Kuang X, Lan L, Wang X. STAT3 regulated long noncoding RNAs lnc7SK and lncIGF2AS promote hepatitis C virus replication. Mol Med Rep 12(5):6738-6744, 2015.
27. Yu F, Zheng J, Mao Y, Dong P, Lu Z, Li G, Guo C, Liu Z, Fan X. Long Non-coding RNA Growth Arrest-specific Transcript 5 (GAS5) Inhibits Liver Fibrogenesis through a Mechanism of Competing Endogenous RNA. J Biol Chem 290(47):28286-28298, 2015.
28. Yuan JH, Yang F, Wang F, Ma JZ, Guo YJ, Tao QF, Liu F, Pan W, Wang TT, Zhou CC, Wang SB, Wang YZ, Yang Y, Yang N, Zhou WP, Yang GS, Sun SH. A long noncoding RNA activated by TGF-beta promotes the invasion-metastasis cascade in hepatocellular carcinoma. Cancer cell 25(5):666-681, 2014.
29. Zhang H, Zhu C, Zhao Y, Li M, Wu L, Yang X, Wan X, Wang A, Zhang M, Sang X, Zhao H. Long non-coding RNA expression profiles of hepatitis Cvirus-related dysplasia and hepatocellular carcinoma. Oncotarget 6(41):43770-43778, 2015a.
30. Zhang Z, Li Y, Fan L, Zhao Q, Tan B, Li Z, Zang A. microRNA-425-5p is upregulated in human gastric cancer and contributes to invasion and metastasis in vitro and in vivo. Exp Ther Med 9(5):1617-1622, 2015b.