MicroRNA-425-5p is upregulated in human gastric cancer and contributes to invasion and metastasis in vitro and in vivo

Experimental and Therapeutic Medicine

Volumn 9, Issue 5, 2015, Pages 1617-1622

  Zhang, Zhuoqi ^a   Li, Yong ^a   Fan, Liqiao ^a   Zhao, Qun ^a   Tan, Bibo ^a   Li, Zhong ^b   Zang, Aimin ^b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI UNIVERSITY   (China)

Author keywords

Gastric cancer; Invasion; Metastasis; MicroRNA 425 5p

Indexed keywords

MATRIGEL; MICRORNA; MICRORNA 425 5P; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; UPREGULATION;

EID: 84925061125     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2015.2318     Document Type: Article

References (26)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin 61: 69-90, 2011.
2. Kamangar F, Dores GM and Anderson WF: Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 24: 2137-2150, 2006.
3. Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127: 2893-2917, 2010.
4. Catalano V, Labianca R, Beretta GD, Gatta G, de Braud F and Van Cutsem E: Gastric cancer. Crit Rev Oncol Hematol 71: 127-164, 2009.
5. Parkin DM, Bray F, Ferlay and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108, 2005.
6. Chen CZ: MicroRNAs as oncogenes and tumor suppressors. N Engl J Med 353: 1768-1771, 2005.
7. Friedman RC, Farh KK, Burge CB and Bartel DP: Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19: 92-105, 2009.
8. Carthew RW and Sontheimer EJ: Origins and mechanisms of miRNAs and siRNAs. Cell 136: 642-655, 2009.
9. Mirnezami AH, Pickard K, Zhang L, Primrose JN and Packham G: MicroRNAs: key players in carcinogenesis and novel therapeutic targets. Eur J Surg Oncol 35: 339-347, 2009.
10. Ruan K, Fang X and Ouyang G: MicroRNAs: novel regulators in the hallmarks of human cancer. Cancer Lett 285: 116-126, 2009.
11. Kim K, Chadalapaka G, Pathi SS, et al: Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters. Mol Cancer Ther 11: 1852-1862, 2012.
12. Selcuklu SD, Donoghue MT, Rehmet K, et al: MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells. J Biol Chem 287: 29516-29528, 2012.
13. Dey N, Das F, Ghosh-Choudhury N, et al: microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion. PLoS One 7: e37366, 2012.
14. He HC, Zhu JG, Chen XB, et al: MicroRNA-23b downregulates peroxiredoxin III in human prostate cancer. FEBS Lett 586: 2451-2458, 2012.
15. Hur K, Toiyama Y, Takahashi M, et al: MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. Gut 62: 1315-1326, 2012.
16. Ueda T, Volinia S, Okumura H, et al: Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol 11: 136-146, 2010.
17. Di Leva G, Piovan C, Gasparini P, et al: Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status. PLoS Genet 9: e1003311, 2013.
18. Peng WZ, Ma R, Wang F, Yu J and Liu ZB: Role of miR-191/425 cluster in tumorigenesis and diagnosis of gastric cancer, Int J Mol Sci 15: 4031-4048, 2014.
19. Sander S, Bullinger L, Klapproth K, Fiedler K, et al: MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood 112: 4202-4212, 2008.
20. Jazbutyte V and Thum T: MicroRNA-21: from cancer to cardiovascular disease. Current Drug Targets 11: 926-935, 2010.
21. Uziel T, Karginov FV, Xie S, Parker JS, et al: The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma. Proc Natl Acad Sci USA 106: 2812-2817, 2009.
22. Bryant RJ, Pawlowski T, Catto JW, Marsden G, et al: Changes in circulating microRNA levels associated with prostate cancer, Br J Cancer 106: 768-774, 2012.
23. Wang M, Gu H, Qian H, Zhu W, et al: miR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation. Eur J Cancer 49 2010-2021, 2013.
24. Mavrakis KJ, Wolfe AL, Oricchio E, Palomero T, et al: Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia. Nat Cell Biol 12: 372-379, 2010.
25. Hsu KW, Wang AM, Ping YH, Huang KH, et al: Downregulation of tumor suppressor MBP-1 by microRNA-363 in gastric carcinogenesis, Carcinogenesis 35: 208-217, 2014.
26. Ma J, Liu J, Wang Z, et al: NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1beta induction. Mol Cancer 13: 40, 2014.