Capsule-targeting depolymerase, derived from klebsiella KP36 phage, as a tool for the development of anti-virulent strategy

Viruses

Volumn 8, Issue 12, 2016, Pages

  Majkowska Skrobek, Grażyna ^a   Łątka, Agnieszka ^a   Berisio, Rita ^b   Maciejewska, Barbara ^a   Squeglia, Flavia ^b   Romano, Maria ^b   Lavigne, Rob ^c   Struve, Carsten ^d,e   Drulis Kawa, Zuzanna ^a  

^a UNIVERSITY OF WROC AW   (Poland)

^b CNR   (Italy)

^c LABORATORY OF GENE TECHNOLOGY   (Belgium)

^d STATENS SERUM INSTITUT   (Denmark)

^e WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Bacteriophage; Capsule; Klebsiella sp.; Polysaccharide depolymerase

Indexed keywords

DEPOLYMERASE; GENOMIC DNA; GENTAMICIN; UNCLASSIFIED DRUG; VIROTHERAPY AGENT; VIRULENCE FACTOR; VIRUS ENZYME; ANTIINFECTIVE AGENT; GLYCOSIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; ARTICLE; ASPERGILLUS NIGER; BACTERIAL CAPSULE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOINFORMATICS; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME STABILITY; GALLERIA MELLONELLA; GENOME ANALYSIS; KLEBSIELLA KP36 PHAGE; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; LIGHT SCATTERING; MELTING POINT; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; TEMPERATURE; TRANSMISSION ELECTRON MICROSCOPY; VIRUS GENOME; ZYMOGRAPHY; ANIMAL; BACTERIOPHAGE; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION; GENETICS; KLEBSIELLA INFECTIONS; LEPIDOPTERA; METABOLISM; MICROBIOLOGY; MOLECULAR WEIGHT; PROTEIN CONFORMATION; RADIATION RESPONSE; TREATMENT OUTCOME; VIROLOGY;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL CAPSULES; BACTERIOPHAGES; CIRCULAR DICHROISM; CLONING, MOLECULAR; DISEASE MODELS, ANIMAL; ENZYME STABILITY; GENE EXPRESSION; GLYCOSIDE HYDROLASES; HYDROGEN-ION CONCENTRATION; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LEPIDOPTERA; MOLECULAR WEIGHT; PROTEIN CONFORMATION; TEMPERATURE; TREATMENT OUTCOME;

EID: 85007092570     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v8120324     Document Type: Article

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