Leptin changes differentiation fate and induces senescence in chondrogenic progenitor cells

Cell Death and Disease

Volumn 7, Issue 4, 2016, Pages

  Zhao, X ^a   Dong, Y ^b   Zhang, J ^a   Li, D ^a   Hu, G ^a   Yao, J ^a   Li, Y ^a   Huang, P ^a   Zhang, M ^a   Huang, Z ^a   Zhang, Y ^a   Miao, Y ^a   Xu, Q ^a   Li, H ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Department of Ultrasound The First People s Hospital of Lianyungang   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; PROTEIN P21; PROTEIN P53; SIRTUIN 1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; SIRT1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE; CARTILAGE DEGENERATION; CELL AGING; CELL CYCLE ARREST; CELL DENSITY; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CELL SELECTION; CHONDROCYTE; CHONDROGENESIS; CLONOGENESIS; CONTROLLED STUDY; DRUG MEGADOSE; FEMALE; HUMAN; HUMAN TISSUE; INTRACELLULAR SIGNALING; LOW DRUG DOSE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OSTEOARTHRITIS; PHENOTYPE; PRIORITY JOURNAL; RAT; SINGLE CELL SORTING; STEM CELL; STEM CELL SELF-RENEWAL; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL CYCLE CHECKPOINT; CELL MOTION; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; MIDDLE AGED; PATHOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CARTILAGE; CELL AGING; CELL CYCLE CHECKPOINTS; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CYCLIN-DEPENDENT KINASE INHIBITOR P21; HUMANS; LEPTIN; MICE; MICE, KNOCKOUT; MIDDLE AGED; OSTEOARTHRITIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SIRTUIN 1; STEM CELLS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 85006796634     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2016.68     Document Type: Article

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