메뉴 건너뛰기




Volumn 5, Issue 12, 2016, Pages 1389-1395

Modulating and Measuring Intracellular H2O2 Using Genetically Encoded Tools to Study Its Toxicity to Human Cells

Author keywords

chemotherapeutics; d amino acid oxidase; hydrogen peroxide; HyPer; quantitative redox biology; toxicity

Indexed keywords

DEXTRO AMINO ACID OXIDASE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE;

EID: 85006483447     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.6b00120     Document Type: Letter
Times cited : (29)

References (40)
  • 1
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
    • D’Autréaux, B. and Toledano, M. B. ( 2007 ) ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis Nat. Rev. Mol. Cell Biol. 8, 813-24 10.1038/nrm2256
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 813-824
    • D’Autréaux, B.1    Toledano, M.B.2
  • 3
    • 42249088093 scopus 로고    scopus 로고
    • Reconciling the chemistry and biology of reactive oxygen species
    • Winterbourn, C. C. ( 2008 ) Reconciling the chemistry and biology of reactive oxygen species Nat. Chem. Biol. 4, 278-86 10.1038/nchembio.85
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 278-286
    • Winterbourn, C.C.1
  • 5
    • 80055008140 scopus 로고    scopus 로고
    • Hydrogen peroxide: a Jekyll and Hyde signalling molecule
    • Gough, D. R. and Cotter, T. G. ( 2011 ) Hydrogen peroxide: a Jekyll and Hyde signalling molecule Cell Death Dis. 2, e213 10.1038/cddis.2011.96
    • (2011) Cell Death Dis. , vol.2 , pp. e213
    • Gough, D.R.1    Cotter, T.G.2
  • 6
    • 0035341719 scopus 로고    scopus 로고
    • 2 induce apoptosis through Fenton chemistry independent of the cellular thiol state
    • 2 induce apoptosis through Fenton chemistry independent of the cellular thiol state Free Radical Biol. Med. 30, 1008-18 10.1016/S0891-5849(01)00493-2
    • (2001) Free Radical Biol. Med. , vol.30 , pp. 1008-1018
    • Antunes, F.1    Cadenas, E.2
  • 10
    • 79960478547 scopus 로고    scopus 로고
    • Chemistry and biology of reactive oxygen species in signaling or stress responses
    • Dickinson, B. C. and Chang, C. J. ( 2011 ) Chemistry and biology of reactive oxygen species in signaling or stress responses Nat. Chem. Biol. 7, 504-11 10.1038/nchembio.607
    • (2011) Nat. Chem. Biol. , vol.7 , pp. 504-511
    • Dickinson, B.C.1    Chang, C.J.2
  • 11
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
    • Bedard, K. and Krause, K.-H. ( 2007 ) The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology Physiol. Rev. 87, 245-313 10.1152/physrev.00044.2005
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.-H.2
  • 12
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
    • Trachootham, D., Alexandre, J., and Huang, P. ( 2009 ) Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat. Rev. Drug Discovery 8, 579-91 10.1038/nrd2803
    • (2009) Nat. Rev. Drug Discovery , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 14
    • 0242668686 scopus 로고    scopus 로고
    • Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling
    • Wood, Z. A., Poole, L. B., and Karplus, P. A. ( 2003 ) Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling Science 300, 650-3 10.1126/science.1080405
    • (2003) Science , vol.300 , pp. 650-653
    • Wood, Z.A.1    Poole, L.B.2    Karplus, P.A.3
  • 15
    • 84869100949 scopus 로고    scopus 로고
    • Subcellular Localization of Oxidants and Redox Modulation of Endothelial Nitric Oxide Synthase
    • Maron, B. A. and Michel, T. ( 2012 ) Subcellular Localization of Oxidants and Redox Modulation of Endothelial Nitric Oxide Synthase Circ. J. 76, 2497-2512 10.1253/circj.CJ-12-1207
    • (2012) Circ. J. , vol.76 , pp. 2497-2512
    • Maron, B.A.1    Michel, T.2
  • 17
    • 0026551386 scopus 로고
    • d-Amino-Acid oxidase and its physiological function
    • Ryuichi, K. and Yosihiro, Y. ( 1992 ) d-Amino-Acid oxidase and its physiological function Int. J. Biochem. 24, 519-524 10.1016/0020-711X(92)90322-R
    • (1992) Int. J. Biochem. , vol.24 , pp. 519-524
    • Ryuichi, K.1    Yosihiro, Y.2
  • 19
  • 20
    • 48749131250 scopus 로고    scopus 로고
    • Transfection of the DAAO gene and subsequent induction of cytotoxic oxidative stress by D-alanine in 9L cells
    • Li, J., Shen, Y., Liu, A., Wang, X., and Zhao, C. ( 2008 ) Transfection of the DAAO gene and subsequent induction of cytotoxic oxidative stress by D-alanine in 9L cells Oncol. Rep. 20, 341-346 10.3892/or.19.2.401
    • (2008) Oncol. Rep. , vol.20 , pp. 341-346
    • Li, J.1    Shen, Y.2    Liu, A.3    Wang, X.4    Zhao, C.5
  • 21
    • 0032548411 scopus 로고    scopus 로고
    • Induction of cytotoxic oxidative stress by D-alanine in brain tumor cells expressing Rhodotorula gracilis D-amino acid oxidase: a cancer gene therapy strategy
    • Stegman, L. D., Zheng, H., Neal, E. R., Ben-Yoseph, O., Pollegioni, L., Pilone, M. S., and Ross, B. D. ( 1998 ) Induction of cytotoxic oxidative stress by D-alanine in brain tumor cells expressing Rhodotorula gracilis D-amino acid oxidase: a cancer gene therapy strategy Hum. Gene Ther. 9, 185-93 10.1089/hum.1998.9.2-185
    • (1998) Hum. Gene Ther. , vol.9 , pp. 185-193
    • Stegman, L.D.1    Zheng, H.2    Neal, E.R.3    Ben-Yoseph, O.4    Pollegioni, L.5    Pilone, M.S.6    Ross, B.D.7
  • 23
    • 84925443050 scopus 로고    scopus 로고
    • Spatial, temporal, and quantitative manipulation of intracellular hydrogen peroxide in cultured cells
    • Alim, I., Haskew-Layton, R. E., Aleyasin, H., Guo, H., and Ratan, R. R. ( 2014 ) Spatial, temporal, and quantitative manipulation of intracellular hydrogen peroxide in cultured cells Methods Enzymol. 547, 251-73 10.1016/B978-0-12-801415-8.00014-X
    • (2014) Methods Enzymol. , vol.547 , pp. 251-273
    • Alim, I.1    Haskew-Layton, R.E.2    Aleyasin, H.3    Guo, H.4    Ratan, R.R.5
  • 26
    • 84890120295 scopus 로고    scopus 로고
    • Genetically encoded fluorescent redox sensors
    • Lukyanov, K. a and Belousov, V. V. ( 2014 ) Genetically encoded fluorescent redox sensors Biochim. Biophys. Acta, Gen. Subj. 1840, 745-56 10.1016/j.bbagen.2013.05.030
    • (2014) Biochim. Biophys. Acta, Gen. Subj. , vol.1840 , pp. 745-756
    • Lukyanov, K.A.1    Belousov, V.V.2
  • 27
    • 16544369973 scopus 로고    scopus 로고
    • Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path
    • Lee, C., Lee, S. M., Mukhopadhyay, P., Kim, S. J., Lee, S. C., Ahn, W.-S., Yu, M.-H., Storz, G., and Ryu, S. E. ( 2004 ) Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path Nat. Struct. Mol. Biol. 11, 1179-85 10.1038/nsmb856
    • (2004) Nat. Struct. Mol. Biol. , vol.11 , pp. 1179-1185
    • Lee, C.1    Lee, S.M.2    Mukhopadhyay, P.3    Kim, S.J.4    Lee, S.C.5    Ahn, W.-S.6    Yu, M.-H.7    Storz, G.8    Ryu, S.E.9
  • 28
    • 84947240985 scopus 로고    scopus 로고
    • Interpreting Heterogeneity in Response of Cells Expressing a Fluorescent Hydrogen Peroxide Biosensor
    • Huang, B. K., Ali, S., Stein, K. T., and Sikes, H. D. ( 2015 ) Interpreting Heterogeneity in Response of Cells Expressing a Fluorescent Hydrogen Peroxide Biosensor Biophys. J. 109, 2148-58 10.1016/j.bpj.2015.08.053
    • (2015) Biophys. J. , vol.109 , pp. 2148-2158
    • Huang, B.K.1    Ali, S.2    Stein, K.T.3    Sikes, H.D.4
  • 29
    • 84908664771 scopus 로고    scopus 로고
    • Quantifying intracellular hydrogen peroxide perturbations in terms of concentration
    • Huang, B. K. and Sikes, H. D. ( 2014 ) Quantifying intracellular hydrogen peroxide perturbations in terms of concentration Redox Biol. 2, 955-962 10.1016/j.redox.2014.08.001
    • (2014) Redox Biol. , vol.2 , pp. 955-962
    • Huang, B.K.1    Sikes, H.D.2
  • 30
  • 31
    • 84855948520 scopus 로고    scopus 로고
    • Dynamic measurements of mitochondrial hydrogen peroxide concentration and glutathione redox state in rat pancreatic β-cells using ratiometric fluorescent proteins: confounding effects of pH with HyPer but not roGFP1
    • Roma, L. P., Duprez, J., Takahashi, H. K., Gilon, P., Wiederkehr, A., and Jonas, J.-C. ( 2012 ) Dynamic measurements of mitochondrial hydrogen peroxide concentration and glutathione redox state in rat pancreatic β-cells using ratiometric fluorescent proteins: confounding effects of pH with HyPer but not roGFP1 Biochem. J. 441, 971-8 10.1042/BJ20111770
    • (2012) Biochem. J. , vol.441 , pp. 971-978
    • Roma, L.P.1    Duprez, J.2    Takahashi, H.K.3    Gilon, P.4    Wiederkehr, A.5    Jonas, J.-C.6
  • 33
    • 33645470326 scopus 로고    scopus 로고
    • Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells
    • Li, C.-Q., Pang, B., Kiziltepe, T., Trudel, L. J., Engelward, B. P., Dedon, P. C., and Wogan, G. N. ( 2006 ) Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells Chem. Res. Toxicol. 19, 399-406 10.1021/tx050283e
    • (2006) Chem. Res. Toxicol. , vol.19 , pp. 399-406
    • Li, C.-Q.1    Pang, B.2    Kiziltepe, T.3    Trudel, L.J.4    Engelward, B.P.5    Dedon, P.C.6    Wogan, G.N.7
  • 34
    • 0242668686 scopus 로고    scopus 로고
    • Peroxiredoxin Evolution and the Signaling
    • Wood, Z. a, Poole, L. B., and Karplus, A. ( 2003 ) Peroxiredoxin Evolution and the Signaling Science 300, 650-653 10.1126/science.1080405
    • (2003) Science , vol.300 , pp. 650-653
    • Wood, Z.A.1    Poole, L.B.2    Karplus, A.3
  • 35
    • 84973862345 scopus 로고    scopus 로고
    • Using sensors and generators of H2O2 to elucidate the toxicity mechanism of piperlongumine and phenethyl isothiocyanate
    • Huang, B. K., Langford, T. F., and Sikes, H. D. ( 2016 ) Using sensors and generators of H2O2 to elucidate the toxicity mechanism of piperlongumine and phenethyl isothiocyanate Antioxid. Redox Signaling 24 ( 16 ) 924-38 10.1089/ars.2015.6482
    • (2016) Antioxid. Redox Signaling , vol.24 , Issue.16 , pp. 924-938
    • Huang, B.K.1    Langford, T.F.2    Sikes, H.D.3
  • 36
    • 84945395305 scopus 로고    scopus 로고
    • Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells
    • Forkink, M., Basit, F., Teixeira, J., Swarts, H. G., Koopman, W. J. H., and Willems, P. H. G. M. ( 2015 ) Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells Redox Biol. 6, 607-616 10.1016/j.redox.2015.09.003
    • (2015) Redox Biol. , vol.6 , pp. 607-616
    • Forkink, M.1    Basit, F.2    Teixeira, J.3    Swarts, H.G.4    Koopman, W.J.H.5    Willems, P.H.G.M.6
  • 38
    • 84941657986 scopus 로고    scopus 로고
    • Analysis of the lifetime and spatial localization of hydrogen peroxide generated in the cytosol using a reduced kinetic model
    • Lim, J. B., Huang, B. K., Deen, W. M., and Sikes, H. D. ( 2015 ) Analysis of the lifetime and spatial localization of hydrogen peroxide generated in the cytosol using a reduced kinetic model Free Radical Biol. Med. 89, 47-53 10.1016/j.freeradbiomed.2015.07.009
    • (2015) Free Radical Biol. Med. , vol.89 , pp. 47-53
    • Lim, J.B.1    Huang, B.K.2    Deen, W.M.3    Sikes, H.D.4
  • 40
    • 1642379545 scopus 로고    scopus 로고
    • Unified equations for the slope, intercept, and standard errors of the best straight line
    • York, D., Evensen, N. M., Martínez, M. L., and De Basabe Delgado, J. ( 2004 ) Unified equations for the slope, intercept, and standard errors of the best straight line Am. J. Phys. 72, 367 10.1119/1.1632486
    • (2004) Am. J. Phys. , vol.72 , pp. 367
    • York, D.1    Evensen, N.M.2    Martínez, M.L.3    De Basabe Delgado, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.