Plasma membrane-bound G protein–coupled bile acid receptor attenuates liver ischemia/reperfusion injury via the inhibition of toll-like receptor 4 signaling in mice

Liver Transplantation

Volumn 23, Issue 1, 2017, Pages 63-74

  Yang, Haojun ^a,b   Zhou, Haoming ^a   Zhuang, Lin ^a   Auwerx, Johan ^c   Schoonjans, Kristina ^c   Wang, Xuehao ^a   Feng, Cheng ^a   Lu, Ling ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 8; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 10; INTERLEUKIN 6; PLASMA MEMBRANE BOUND G PROTEIN COUPLED BILE ACID RECEPTOR; PROTEIN KINASE B; RECEPTOR; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 6ALPHA-ETHYL-23(S)-METHYLCHOLIC ACID; CASP8 PROTEIN, MOUSE; CHOLIC ACID DERIVATIVE; G PROTEIN COUPLED RECEPTOR; GPBAR1 PROTEIN, MOUSE; INTERLEUKIN-6, MOUSE; TLR4 PROTEIN, MOUSE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BONE MARROW DERIVED MACROPHAGE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME ACTIVATION; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INFLAMMATORY CELL; INTRACELLULAR SIGNALING; LIVER CELL; LIVER ISCHEMIA; MALE; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; TISSUE SECTION; UPREGULATION; WILD TYPE; ADVERSE EFFECTS; ANIMAL; APOPTOSIS; BLOOD; C57BL MOUSE; CELL MEMBRANE; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; LIVER; LIVER TRANSPLANTATION; MACROPHAGE; METABOLISM; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; ULTRASTRUCTURE; WARM ISCHEMIA;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; CASPASE 8; CELL MEMBRANE; CHOLIC ACIDS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; LIVER; LIVER TRANSPLANTATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; PRIMARY CELL CULTURE; RECEPTORS, G-PROTEIN-COUPLED; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; WARM ISCHEMIA;

EID: 85006337549     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.24628     Document Type: Article

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