메뉴 건너뛰기




Volumn 47, Issue 12, 2015, Pages

The Wnt/β-catenin signaling pathway regulates the development of airway remodeling in patients with asthma

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; MESSENGER RNA; SMALL INTERFERING RNA; WNT PROTEIN; WNT7A PROTEIN, HUMAN;

EID: 85006307443     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/EMM.2015.91     Document Type: Article
Times cited : (69)

References (41)
  • 3
    • 0032558685 scopus 로고    scopus 로고
    • A 15-year follow-up study of ventilatory function in adults with asthma
    • Lange P, Parner J, Vestbo J, Schnohr P, Jensen G. A 15-year follow-up study of ventilatory function in adults with asthma. NEnglJMed1998; 339: 1194–1200.
    • (1998) Nengljmed , vol.339 , pp. 1194-1200
    • Lange, P.1    Parner, J.2    Vestbo, J.3    Schnohr, P.4    Jensen, G.5
  • 7
    • 85027928476 scopus 로고    scopus 로고
    • Asthma therapy and its effect on airway remodelling
    • Berair R, Brightling CE. Asthma therapy and its effect on airway remodelling. Drugs 2014; 74: 1345–1369.
    • (2014) Drugs , vol.74 , pp. 1345-1369
    • Berair, R.1    Brightling, C.E.2
  • 8
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009; 17: 9–26.
    • (2009) Dev Cell , vol.17 , pp. 9-26
    • Macdonald, B.T.1    Tamai, K.2    He, X.3
  • 9
    • 36849055111 scopus 로고    scopus 로고
    • SnapShot: Wnt/beta-catenin signaling
    • 1204
    • Macdonald BT, Semenov MV, He X. SnapShot: Wnt/beta-catenin signaling. Cell 2007; 131: 1204.
    • (2007) Cell , vol.131
    • Macdonald, B.T.1    Semenov, M.V.2    He, X.3
  • 10
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers H, Nusse R. Wnt/beta-catenin signaling and disease. Cell 2012; 149: 1192–1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 11
    • 40749157135 scopus 로고    scopus 로고
    • Wnt pathway: A new role in regulation of inflammation
    • George SJ. Wnt pathway: a new role in regulation of inflammation. Arterioscler Thromb Vasc Biol 2008; 28: 400–402.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 400-402
    • George, S.J.1
  • 12
    • 33644827340 scopus 로고    scopus 로고
    • Wnt signalling in lung development and diseases
    • Pongracz JE, Stockley RA. Wnt signalling in lung development and diseases. Respir Res 2006; 7: 15.
    • (2006) Respir Res , vol.7
    • Pongracz, J.E.1    Stockley, R.A.2
  • 14
    • 73949090577 scopus 로고    scopus 로고
    • WNT. signaling in lung disease: A failure or a regeneration signal?
    • Konigshoff M, Eickelberg O. WNT. signaling in lung disease: a failure or a regeneration signal? Am J Respir Cell Mol Biol 2010; 42: 21–31.
    • (2010) Am J Respir Cell Mol Biol , vol.42 , pp. 21-31
    • Konigshoff, M.1    Eickelberg, O.2
  • 15
    • 84868650760 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: A promising new target for fibrosis diseases
    • Guo Y, Xiao L, Sun L, Liu F. Wnt/beta-catenin signaling: a promising new target for fibrosis diseases. Physiol Res 2012; 61: 337–346.
    • (2012) Physiol Res , vol.61 , pp. 337-346
    • Guo, Y.1    Xiao, L.2    Sun, L.3    Liu, F.4
  • 17
    • 0242500879 scopus 로고    scopus 로고
    • Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis
    • Chilosi M, Poletti V, Zamo A, Lestani M, Montagna L, Piccoli P et al. Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am J Pathol 2003; 162: 1495–1502.
    • (2003) Am J Pathol , vol.162 , pp. 1495-1502
    • Chilosi, M.1    Poletti, V.2    Zamo, A.3    Lestani, M.4    Montagna, L.5    Piccoli, P.6
  • 18
    • 79958822662 scopus 로고    scopus 로고
    • Blockade of the Wnt/beta-catenin pathway attenuates bleomycin-induced pulmonary fibrosis
    • Kim TH, Kim SH, Seo JY, Chung H, Kwak HJ, Lee SK et al. Blockade of the Wnt/beta-catenin pathway attenuates bleomycin-induced pulmonary fibrosis. Tohoku J Exp Med 2011; 223: 45–54.
    • (2011) Tohoku J Exp Med , vol.223 , pp. 45-54
    • Kim, T.H.1    Kim, S.H.2    Seo, J.Y.3    Chung, H.4    Kwak, H.J.5    Lee, S.K.6
  • 19
    • 77956288500 scopus 로고    scopus 로고
    • Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
    • Henderson WR Jr., Chi EY, Ye X, Nguyen C, Tien YT, Zhou B et al. Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci USA 2010; 107: 14309–14314.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14309-14314
    • Henderson, W.R.1    Chi, E.Y.2    Ye, X.3    Nguyen, C.4    Tien, Y.T.5    Zhou, B.6
  • 21
    • 0037030495 scopus 로고    scopus 로고
    • Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells
    • Fishman P, Madi L, Bar-Yehuda S, Barer F, Del Valle L, Khalili K. Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells. Oncogene 2002; 21: 4060–4064.
    • (2002) Oncogene , vol.21 , pp. 4060-4064
    • Fishman, P.1    Madi, L.2    Bar-Yehuda, S.3    Barer, F.4    Del Valle, L.5    Khalili, K.6
  • 23
    • 34250719738 scopus 로고    scopus 로고
    • Identification of interleukin-13 related biomarkers using peripheral blood mononuclear cells
    • Syed F, Huang CC, Li K, Liu V, Shang T, Amegadzie BY et al. Identification of interleukin-13 related biomarkers using peripheral blood mononuclear cells. Biomarkers 2007; 12: 414–423.
    • (2007) Biomarkers , vol.12 , pp. 414-423
    • Syed, F.1    Huang, C.C.2    Li, K.3    Liu, V.4    Shang, T.5    Amegadzie, B.Y.6
  • 24
    • 79251582522 scopus 로고    scopus 로고
    • Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways
    • Choy DF, Modrek B, Abbas AR, Kummerfeld S, Clark HF, Wu LC et al. Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways. JImmunol2011; 186: 1861–1869.
    • (2011) Jimmunol , vol.186 , pp. 1861-1869
    • Choy, D.F.1    Modrek, B.2    Abbas, A.R.3    Kummerfeld, S.4    Clark, H.F.5    Wu, L.C.6
  • 26
    • 84878956298 scopus 로고    scopus 로고
    • Genetic variations in the Wnt signaling pathway affect lung function in asthma patients
    • Wang SH, Xu F, Dang HX, Yang L. Genetic variations in the Wnt signaling pathway affect lung function in asthma patients. Genet Mol Res 2013; 12: 1829–1833.
    • (2013) Genet Mol Res , vol.12 , pp. 1829-1833
    • Wang, S.H.1    Xu, F.2    Dang, H.X.3    Yang, L.4
  • 27
    • 84930758074 scopus 로고    scopus 로고
    • Clinical significance of aberrant Wnt7a promoter methylation in human non-small cell lung cancer in Koreans
    • Kim TH, Moon JY, Kim SH, Paik SS, Yoon HJ, Shin DH et al. Clinical significance of aberrant Wnt7a promoter methylation in human non-small cell lung cancer in Koreans. J Korean Med Sci 2015; 30: 155–161.
    • (2015) J Korean Med Sci , vol.30 , pp. 155-161
    • Kim, T.H.1    Moon, J.Y.2    Kim, S.H.3    Paik, S.S.4    Yoon, H.J.5    Shin, D.H.6
  • 30
  • 31
    • 84947565577 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target
    • Enzo MV, Rastrelli M, Rossi CR, Hladnik U, Segat D. The Wnt/beta-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target. Mol Cell Ther 2015; 3: 1.
    • (2015) Mol Cell Ther , vol.3 , pp. 1
    • Enzo, M.V.1    Rastrelli, M.2    Rossi, C.R.3    Hladnik, U.4    Segat, D.5
  • 32
    • 82955232388 scopus 로고    scopus 로고
    • beta-catenin signaling: A novel mediator of fibrosis and potential therapeutic target
    • Lam AP, Gottardi CJ. beta-catenin signaling: a novel mediator of fibrosis and potential therapeutic target. Curr Opin Rheumatol 2011; 23: 562–567.
    • (2011) Curr Opin Rheumatol , vol.23 , pp. 562-567
    • Lam, A.P.1    Gottardi, C.J.2
  • 33
    • 75149193602 scopus 로고    scopus 로고
    • Interaction of wingless protein (Wnt), transforming growth factor-beta1, and hyaluronan production in fetal and postnatal fibroblasts
    • Carre AL, James AW, MacLeod L, Kong W, Kawai K, Longaker MT et al. Interaction of wingless protein (Wnt), transforming growth factor-beta1, and hyaluronan production in fetal and postnatal fibroblasts. Plast Reconstr Surg 2010; 125: 74–88.
    • (2010) Plast Reconstr Surg , vol.125 , pp. 74-88
    • Carre, A.L.1    James, A.W.2    Macleod, L.3    Kong, W.4    Kawai, K.5    Longaker, M.T.6
  • 34
    • 33646242018 scopus 로고    scopus 로고
    • Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing
    • Cheon SS, Wei Q, Gurung A, Youn A, Bright T, Poon R et al. Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing. Faseb j 2006; 20: 692–701.
    • (2006) Faseb J , vol.20 , pp. 692-701
    • Cheon, S.S.1    Wei, Q.2    Gurung, A.3    Youn, A.4    Bright, T.5    Poon, R.6
  • 35
    • 84922595423 scopus 로고    scopus 로고
    • Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling
    • Noble PB, Pascoe CD, Lan B, Ito S, Kistemaker LE, Tatler AL et al. Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling. Pulm Pharmacol Ther 2014; 29: 96–107.
    • (2014) Pulm Pharmacol Ther , vol.29 , pp. 96-107
    • Noble, P.B.1    Pascoe, C.D.2    Lan, B.3    Ito, S.4    Kistemaker, L.E.5    Tatler, A.L.6
  • 36
    • 84890351899 scopus 로고    scopus 로고
    • Airway smooth muscle in airway reactivity and remodeling: What have we learned?
    • Prakash YS. Airway smooth muscle in airway reactivity and remodeling: what have we learned? Am J Physiol Lung Cell Mol Physiol 2013; 305: L912–L933.
    • (2013) Am J Physiol Lung Cell Mol Physiol , vol.305 , pp. L912-L933
    • Prakash, Y.S.1
  • 37
    • 84878492702 scopus 로고    scopus 로고
    • Origins of increased airway smooth muscle mass in asthma
    • Berair R, Saunders R, Brightling CE. Origins of increased airway smooth muscle mass in asthma. BMC Med 2013; 11: 145.
    • (2013) BMC Med , vol.11
    • Berair, R.1    Saunders, R.2    Brightling, C.E.3
  • 39
    • 0029915964 scopus 로고    scopus 로고
    • PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells
    • Hirst SJ, Barnes PJ, Twort CH. PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells. Am J Physiol 1996; 270: L415–L428.
    • (1996) Am J Physiol , vol.270 , pp. L415-L428
    • Hirst, S.J.1    Barnes, P.J.2    Twort, C.H.3
  • 40
    • 68349155775 scopus 로고    scopus 로고
    • Plateletderived growth factor and transforming growth factor-beta modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells
    • Ito I, Fixman ED, Asai K, Yoshida M, Gounni AS, Martin JG et al. Plateletderived growth factor and transforming growth factor-beta modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells. Clin Exp Allergy 2009; 39: 1370–1380.
    • (2009) Clin Exp Allergy , vol.39 , pp. 1370-1380
    • Ito, I.1    Fixman, E.D.2    Asai, K.3    Yoshida, M.4    Gounni, A.S.5    Martin, J.G.6
  • 41
    • 70349211744 scopus 로고    scopus 로고
    • Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway
    • Cohen ED, Ihida-Stansbury K, Lu MM, Panettieri RA, Jones PL, Morrisey EE. Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway. JClinInvest2009; 119: 2538–2549.
    • (2009) Jclininvest , vol.119 , pp. 2538-2549
    • Cohen, E.D.1    Ihida-Stansbury, K.2    Lu, M.M.3    Panettieri, R.A.4    Jones, P.L.5    Morrisey, E.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.