Platelet-derived growth factor and transforming growth factor-β modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells

Clinical and Experimental Allergy

Volumn 39, Issue 9, 2009, Pages 1370-1380

  Ito, I ^a   Fixman, E D ^a   Asai, K ^a   Yoshida, M ^b   Gounni, A S ^c   Martin, J G ^a   Hamid, Q ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Airway remodelling; Airway smooth muscle cells; Asthma; Matrix metalloproteinase; Platelet derived growth factor; TGF

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; GELATINASE A; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA; UO 126;

ARTICLE; BREATHING MUSCLE; CELL CULTURE; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SMOOTH MUSCLE FIBER; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY;

BENZAMIDES; BUTADIENES; CELL MOVEMENT; CELLS, CULTURED; DIOXOLES; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASES; MYOCYTES, SMOOTH MUSCLE; NITRILES; PLATELET-DERIVED GROWTH FACTOR; RNA INTERFERENCE; SMAD PROTEINS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 68349155775     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2009.03293.x     Document Type: Article

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