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Volumn 5, Issue 4, 2016, Pages 703-710

Three-dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer

Author keywords

3D microtissue; Combination; HER2 knockdown; Model; Mouse xenografts; Radiation; Spheroid; Trastuzumab

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; TRASTUZUMAB; ANTINEOPLASTIC AGENT;

EID: 85006213857     PISSN: None     EISSN: 20457634     Source Type: Journal    
DOI: 10.1002/cam4.630     Document Type: Article
Times cited : (28)

References (29)
  • 1
    • 0042358985 scopus 로고    scopus 로고
    • Cell culture: biology's new dimension
    • Abbott, A. 2003. Cell culture: biology's new dimension. Nature 424:870-872.
    • (2003) Nature , vol.424 , pp. 870-872
    • Abbott, A.1
  • 2
    • 77955275498 scopus 로고    scopus 로고
    • Efficacy of anti-cancer agents in cell lines versus human primary tumour tissue
    • Cree, I. A., S. Glaysher, and A. L. Harvey . 2010. Efficacy of anti-cancer agents in cell lines versus human primary tumour tissue. Curr. Opin. Pharmacol. 10:375-379.
    • (2010) Curr. Opin. Pharmacol. , vol.10 , pp. 375-379
    • Cree, I.A.1    Glaysher, S.2    Harvey, A.L.3
  • 3
    • 84906816780 scopus 로고    scopus 로고
    • Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo
    • Hickman, J. A., R. Graeser, de Hoogt R., S. Vidic, C. Brito, M. Gutekunst, et al. 2014. Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo. Biotechnol. J. 9:1115-1128.
    • (2014) Biotechnol. J. , vol.9 , pp. 1115-1128
    • Hickman, J.A.1    Graeser, R.2    de Hoogt, R.3    Vidic, S.4    Brito, C.5    Gutekunst, M.6
  • 4
    • 0014984766 scopus 로고
    • Growth of multicell spheroids in tissue culture as a model of nodular carcinomas
    • Sutherland, R. M., J. A. McCredie, and W. R. Inch . 1971. Growth of multicell spheroids in tissue culture as a model of nodular carcinomas. J. Natl Cancer Inst. 46:113-120.
    • (1971) J. Natl Cancer Inst. , vol.46 , pp. 113-120
    • Sutherland, R.M.1    McCredie, J.A.2    Inch, W.R.3
  • 5
    • 0035030266 scopus 로고    scopus 로고
    • Pattern of self-organization in tumour systems: complex growth dynamics in a novel brain tumour spheroid model
    • Deisboeck, T. S., M. E. Berens, A. R. Kansal, S. Torquato, A. O. Stemmer-Rachamimov, and E. A. Chiocca . 2001. Pattern of self-organization in tumour systems: complex growth dynamics in a novel brain tumour spheroid model. Cell Prolif. 34:115-134.
    • (2001) Cell Prolif. , vol.34 , pp. 115-134
    • Deisboeck, T.S.1    Berens, M.E.2    Kansal, A.R.3    Torquato, S.4    Stemmer-Rachamimov, A.O.5    Chiocca, E.A.6
  • 6
    • 83455236148 scopus 로고    scopus 로고
    • Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues
    • Drewitz, M., M. Helbling, N. Fried, M. Bieri, W. Moritz, J. Lichtenberg, et al. 2011. Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues. Biotechnol. J. 6:1488-1496.
    • (2011) Biotechnol. J. , vol.6 , pp. 1488-1496
    • Drewitz, M.1    Helbling, M.2    Fried, N.3    Bieri, M.4    Moritz, W.5    Lichtenberg, J.6
  • 7
    • 0035073872 scopus 로고    scopus 로고
    • Tumor-induced angiogenesis studied in confrontation cultures of multicellular tumor spheroids and embryoid bodies grown from pluripotent embryonic stem cells
    • Wartenberg, M., F. Donmez, F. C. Ling, H. Acker, J. Hescheler, and H. Sauer . 2001. Tumor-induced angiogenesis studied in confrontation cultures of multicellular tumor spheroids and embryoid bodies grown from pluripotent embryonic stem cells. FASEB J. 15:995-1005.
    • (2001) FASEB J. , vol.15 , pp. 995-1005
    • Wartenberg, M.1    Donmez, F.2    Ling, F.C.3    Acker, H.4    Hescheler, J.5    Sauer, H.6
  • 8
    • 38449101699 scopus 로고    scopus 로고
    • Diversity of cell-mediated adhesions in breast cancer spheroids
    • Ivascu, A., and M. Kubbies . 2007. Diversity of cell-mediated adhesions in breast cancer spheroids. Int. J. Oncol. 31:1403-1413.
    • (2007) Int. J. Oncol. , vol.31 , pp. 1403-1413
    • Ivascu, A.1    Kubbies, M.2
  • 9
    • 84858723379 scopus 로고    scopus 로고
    • Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation
    • Vinci, M., S. Gowan, F. Boxall, L. Patterson, M. Zimmermann, W. Court, et al. 2012. Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation. BMC Biol. 10:29.
    • (2012) BMC Biol. , vol.10 , pp. 29
    • Vinci, M.1    Gowan, S.2    Boxall, F.3    Patterson, L.4    Zimmermann, M.5    Court, W.6
  • 10
    • 84856079488 scopus 로고    scopus 로고
    • Protein and phosphoprotein levels in glioma and adenocarcinoma cell lines grown in normoxia and hypoxia in monolayer and three-dimensional cultures
    • Levin, V. A., S. Panchabhai, L. Shen, and K. A. Baggerly . 2012. Protein and phosphoprotein levels in glioma and adenocarcinoma cell lines grown in normoxia and hypoxia in monolayer and three-dimensional cultures. Proteome Sci. 10:5.
    • (2012) Proteome Sci. , vol.10 , pp. 5
    • Levin, V.A.1    Panchabhai, S.2    Shen, L.3    Baggerly, K.A.4
  • 11
    • 84899945356 scopus 로고    scopus 로고
    • 3D cell culture systems modeling tumor growth determinants in cancer target discovery
    • Thoma, C. R., M. Zimmermann, I. Agarkova, J. M. Kelm, and W. Krek . 2014. 3D cell culture systems modeling tumor growth determinants in cancer target discovery. Adv. Drug Deliv. Rev. 69-70:29-41.
    • (2014) Adv. Drug Deliv. Rev. , vol.69-70 , pp. 29-41
    • Thoma, C.R.1    Zimmermann, M.2    Agarkova, I.3    Kelm, J.M.4    Krek, W.5
  • 12
    • 71049168885 scopus 로고    scopus 로고
    • Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high-throughput three-dimensional culture: example of the breast epithelium
    • Plachot, C., L. S. Chaboub, H. A. Adissu, L. Wang, A. Urazaev, J. Sturgis, et al. 2009. Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high-throughput three-dimensional culture: example of the breast epithelium. BMC Biol. 7:77.
    • (2009) BMC Biol. , vol.7 , pp. 77
    • Plachot, C.1    Chaboub, L.S.2    Adissu, H.A.3    Wang, L.4    Urazaev, A.5    Sturgis, J.6
  • 13
    • 79954459766 scopus 로고    scopus 로고
    • Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer
    • Ludyga, N., N. Anastasov, I. Gonzalez-Vasconcellos, M. Ram, H. Hofler, and M. Aubele . 2011. Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer. Mol. BioSyst. 7:1603-1612.
    • (2011) Mol. BioSyst. , vol.7 , pp. 1603-1612
    • Ludyga, N.1    Anastasov, N.2    Gonzalez-Vasconcellos, I.3    Ram, M.4    Hofler, H.5    Aubele, M.6
  • 14
    • 84876514602 scopus 로고    scopus 로고
    • Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells
    • Ludyga, N., N. Anastasov, M. Rosemann, J. Seiler, N. Lohmann, H. Braselmann, et al. 2013. Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells. Mol. Cancer Res. 11:381-392.
    • (2013) Mol. Cancer Res. , vol.11 , pp. 381-392
    • Ludyga, N.1    Anastasov, N.2    Rosemann, M.3    Seiler, J.4    Lohmann, N.5    Braselmann, H.6
  • 15
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon, D. J., W. Godolphin, L. A. Jones, J. A. Holt, S. G. Wong, D. E. Keith, et al. 1989. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244:707-712.
    • (1989) Science , vol.244 , pp. 707-712
    • Slamon, D.J.1    Godolphin, W.2    Jones, L.A.3    Holt, J.A.4    Wong, S.G.5    Keith, D.E.6
  • 16
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • Baselga, J., L. Norton, J. Albanell, Y. M. Kim, and J. Mendelsohn . 1998. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res. 58:2825-2831.
    • (1998) Cancer Res. , vol.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3    Kim, Y.M.4    Mendelsohn, J.5
  • 17
    • 84870384133 scopus 로고    scopus 로고
    • Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells
    • Anastasov, N., I. Hofig, I. G. Vasconcellos, K. Rappl, H. Braselmann, N. Ludyga, et al. 2012. Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells. Radiat. Oncol. 7:206.
    • (2012) Radiat. Oncol. , vol.7 , pp. 206
    • Anastasov, N.1    Hofig, I.2    Vasconcellos, I.G.3    Rappl, K.4    Braselmann, H.5    Ludyga, N.6
  • 19
    • 85019238702 scopus 로고    scopus 로고
    • A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment
    • Anastasov, N., I. Hofig, V. Radulovic, S. Strobel, M. Salomon, J. Lichtenberg, et al. 2015. A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment. BMC Cancer 15:466.
    • (2015) BMC Cancer , vol.15 , pp. 466
    • Anastasov, N.1    Hofig, I.2    Radulovic, V.3    Strobel, S.4    Salomon, M.5    Lichtenberg, J.6
  • 20
    • 84859270363 scopus 로고    scopus 로고
    • Label-free protein profiling of formalin-fixed paraffin-embedded (FFPE) heart tissue reveals immediate mitochondrial impairment after ionising radiation
    • Azimzadeh, O., H. Scherthan, R. Yentrapalli, Z. Barjaktarovic, M. Ueffing, M. Conrad, et al. 2012. Label-free protein profiling of formalin-fixed paraffin-embedded (FFPE) heart tissue reveals immediate mitochondrial impairment after ionising radiation. J. Proteomics. 75:2384-2395.
    • (2012) J. Proteomics. , vol.75 , pp. 2384-2395
    • Azimzadeh, O.1    Scherthan, H.2    Yentrapalli, R.3    Barjaktarovic, Z.4    Ueffing, M.5    Conrad, M.6
  • 21
    • 77955981271 scopus 로고    scopus 로고
    • In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues
    • Aubele, M., M. Spears, N. Ludyga, H. Braselmann, A. Feuchtinger, K. J. Taylor, et al. 2010. In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues. Br. J. Cancer 103:663-667.
    • (2010) Br. J. Cancer , vol.103 , pp. 663-667
    • Aubele, M.1    Spears, M.2    Ludyga, N.3    Braselmann, H.4    Feuchtinger, A.5    Taylor, K.J.6
  • 23
    • 77953359099 scopus 로고    scopus 로고
    • Multiple molecular mechanisms underlying trastuzumab and lapatinib resistance in JIMT-1 breast cancer cells
    • Koninki, K., M. Barok, M. Tanner, S. Staff, J. Pitkanen, P. Hemmila, et al. 2010. Multiple molecular mechanisms underlying trastuzumab and lapatinib resistance in JIMT-1 breast cancer cells. Cancer Lett. 294:211-219.
    • (2010) Cancer Lett. , vol.294 , pp. 211-219
    • Koninki, K.1    Barok, M.2    Tanner, M.3    Staff, S.4    Pitkanen, J.5    Hemmila, P.6
  • 24
    • 84877289520 scopus 로고    scopus 로고
    • Gamma-irradiation induces HER-2/neu overexpression in breast cancer cell lines and sensitivity to treatment with trastuzumab
    • Voutsas, I. F., L. G. Mahaira, K. Fotopoulou, N. Kapranos, J. G. Reclos, A. D. Gritzapis, et al. 2013. Gamma-irradiation induces HER-2/neu overexpression in breast cancer cell lines and sensitivity to treatment with trastuzumab. Int. J. Radiat. Biol. 89:319-325.
    • (2013) Int. J. Radiat. Biol. , vol.89 , pp. 319-325
    • Voutsas, I.F.1    Mahaira, L.G.2    Fotopoulou, K.3    Kapranos, N.4    Reclos, J.G.5    Gritzapis, A.D.6
  • 25
    • 84896495551 scopus 로고    scopus 로고
    • Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets
    • Wattenberg, M. M., A. R. Kwilas, S. R. Gameiro, A. P. Dicker, and J. W. Hodge . 2014. Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Br. J. Cancer 110:1472-1480.
    • (2014) Br. J. Cancer , vol.110 , pp. 1472-1480
    • Wattenberg, M.M.1    Kwilas, A.R.2    Gameiro, S.R.3    Dicker, A.P.4    Hodge, J.W.5
  • 26
    • 84871188682 scopus 로고    scopus 로고
    • HER2-associated radioresistance of breast cancer stem cells isolated from HER2-negative breast cancer cells
    • Duru, N., M. Fan, D. Candas, C. Menaa, H. C. Liu, D. Nantajit, et al. 2012. HER2-associated radioresistance of breast cancer stem cells isolated from HER2-negative breast cancer cells. Clin. Cancer Res. 18:6634-6647.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 6634-6647
    • Duru, N.1    Fan, M.2    Candas, D.3    Menaa, C.4    Liu, H.C.5    Nantajit, D.6
  • 27
    • 84945588907 scopus 로고    scopus 로고
    • Autophagy protects from trastuzumab-induced cytotoxicity in HER2 overexpressing breast tumor spheroids
    • Rodriguez, C. E., S. I. Reidel, Bal de Kier Joffe E. D., M. A. Jasnis, and G. L. Fiszman . 2015. Autophagy protects from trastuzumab-induced cytotoxicity in HER2 overexpressing breast tumor spheroids. PLoS ONE 10:e0137920.
    • (2015) PLoS ONE , vol.10 , pp. e0137920
    • Rodriguez, C.E.1    Reidel, S.I.2    Bal de Kier Joffe, E.D.3    Jasnis, M.A.4    Fiszman, G.L.5
  • 28
    • 81055155920 scopus 로고    scopus 로고
    • Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials
    • Early Breast Cancer Trialists' Collaborative G
    • Early Breast Cancer Trialists' Collaborative G, S. Darby, P. McGale, C. Correa, C. Taylor, R. Arriagada, M. Clarke, et al. 2011. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10, 801 women in 17 randomised trials. Lancet 378:1707-1716.
    • (2011) Lancet , vol.378 , pp. 1707-1716
    • Darby, S.1    McGale, P.2    Correa, C.3    Taylor, C.4    Arriagada, R.5    Clarke, M.6
  • 29
    • 84891682209 scopus 로고    scopus 로고
    • An injectable spheroid system with genetic modification for cell transplantation therapy
    • Uchida, S., K. Itaka, T. Nomoto, T. Endo, Y. Matsumoto, T. Ishii, et al. 2014. An injectable spheroid system with genetic modification for cell transplantation therapy. Biomaterials 35:2499-2506.
    • (2014) Biomaterials , vol.35 , pp. 2499-2506
    • Uchida, S.1    Itaka, K.2    Nomoto, T.3    Endo, T.4    Matsumoto, Y.5    Ishii, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.