Fenofibrate, a PPARα agonist, protect proximal tubular cells from albumin-bound fatty acids induced apoptosis via the activation of NF-κB

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 9, 2015, Pages 10653-10661

  Zuo, Nan ^a   Zheng, Xiaoyu ^a   Liu, Hanzhe ^a   Ma, Xiaoli ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Chronic kidney disease; Fatty acids; Fenofibrate; Peroxisome proliferator activated receptor a; Proximal tubule epithelial cells

Indexed keywords

BOVINE SERUM ALBUMIN; CCL2 PROTEIN, HUMAN; FATTY ACID; FENOFIBRATE; IL8 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MALONALDEHYDE; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN BINDING; SUPEROXIDE DISMUTASE;

AGONISTS; APOPTOSIS; CELL LINE; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETICS; HUMAN; KIDNEY PROXIMAL TUBULE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UPREGULATION;

APOPTOSIS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHEMOKINE CCL2; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS; FENOFIBRATE; HUMANS; INTERLEUKIN-8; KIDNEY TUBULES, PROXIMAL; MALONDIALDEHYDE; NF-KAPPA B; OXIDATIVE STRESS; PPAR ALPHA; PROTEIN BINDING; SERUM ALBUMIN, BOVINE; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 85006147617     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

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