Neutrophils promote alveolar epithelial regeneration by enhancing type ii pneumocyte proliferation in a model of acid-induced acute lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 311, Issue 6, 2016, Pages L1062-L1075

  Paris, Andrew J ^a,b   Liu, Yuhong ^c,d   Mei, Junjie ^c,d   Dai, Ning ^c,d   Guo, Lei ^e   Spruce, Lynn A ^c   Hudock, Kristin M ^a,b,f   Brenner, Jacob S ^a,b   Zacharias, William J ^a,b   Mei, Hankun D ^c,d   Slamowitz, April R ^g   Bhamidipati, Kartik ^b   Beers, Michael F ^a,b   Seeholzer, Steven H ^c   Morrisey, Edward E ^b,d   Worthen, G Scott ^b,c,d  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e INSTITUTE OF MEDICAL BIOLOGY   (China)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^g DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

Author keywords

Acute respiratory distress syndrome; Granulocyte colony stimulating factor; Neutrophils; Pneumocyte; Regeneration

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; ACID; ANTIBODY;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL EXPERIMENT; ARTICLE; BRONCHOALVEOLAR LAVAGE FLUID; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; CYTOKINE RESPONSE; EPITHELIZATION; FEMALE; IN VIVO STUDY; INJURY SEVERITY; INNATE IMMUNITY; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; TISSUE REPAIR; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; EPITHELIUM; LUNG ALVEOLUS EPITHELIUM CELL; METABOLISM; PATHOLOGY; PROTEOMICS; REGENERATION; UPREGULATION; WOUND HEALING;

ACIDS; ACUTE LUNG INJURY; ALVEOLAR EPITHELIAL CELLS; ANIMALS; ANTIBODIES; BRONCHOALVEOLAR LAVAGE FLUID; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; EPITHELIUM; GRANULOCYTE COLONY-STIMULATING FACTOR; MICE, INBRED C57BL; NEUTROPHILS; PROTEOMICS; REGENERATION; RESPIRATORY DISTRESS SYNDROME, ADULT; SIGNAL TRANSDUCTION; UP-REGULATION; WOUND HEALING;

EID: 85006012964     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00327.2016     Document Type: Article

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