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Volumn 6, Issue , 2016, Pages

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18; PROPYLTHIOURACIL; THYROXINE;

EID: 85006010469     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep38124     Document Type: Article
Times cited : (69)

References (47)
  • 1
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose Tissue: Function and physiological significance
    • Cannon, B., Nedergaard, J. Brown Adipose Tissue: Function and Physiological Significance. Physiol. Rev. 84, 277-359 (2004).
    • (2004) Physiol. Rev , vol.84 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 2
    • 0042200747 scopus 로고    scopus 로고
    • The thermogenic effect of thyroid hormone and its clinical implications
    • Silva, J. E. The Thermogenic Effect of Thyroid Hormone and Its Clinical Implications. Ann. Intern. Med. 139, 205-213 (2003).
    • (2003) Ann. Intern. Med , vol.139 , pp. 205-213
    • Silva, J.E.1
  • 3
    • 0024362168 scopus 로고
    • Role of thermogenesis in the regulation of energy balance in relation to obesity
    • Himms-Hagen, J. Role of thermogenesis in the regulation of energy balance in relation to obesity. Can. J. Physiol. Pharmacol. 67, 394-401 (1989).
    • (1989) Can. J. Physiol. Pharmacol , vol.67 , pp. 394-401
    • Himms-Hagen, J.1
  • 4
    • 33947222099 scopus 로고    scopus 로고
    • Impaired adipogenesis caused by a mutated thyroid hormone alpha1 receptor
    • Ying, H., Araki, O., Furuya, F., Kato, Y., Cheng, S.-Y. Impaired adipogenesis caused by a mutated thyroid hormone alpha1 receptor. Mol. Cell. Biol. 27, 2359-2371 (2007).
    • (2007) Mol. Cell. Biol , vol.27 , pp. 2359-2371
    • Ying, H.1    Araki, O.2    Furuya, F.3    Kato, Y.4    Cheng, S.-Y.5
  • 5
    • 0034932901 scopus 로고    scopus 로고
    • Thyroid hormone-sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform-specific
    • Ribeiro, M. O. et al. Thyroid hormone-sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform-specific. J. Clin. Invest. 108, 97-105 (2001).
    • (2001) J. Clin. Invest , vol.108 , pp. 97-105
    • Ribeiro, M.O.1
  • 6
    • 10744221610 scopus 로고    scopus 로고
    • Mice with targeted disruption of the dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis
    • Christoffolete, M. A. et al. Mice with Targeted Disruption of the Dio2 Gene Have Cold-Induced Overexpression of the Uncoupling Protein 1 Gene but Fail to Increase Brown Adipose Tissue Lipogenesis and Adaptive Thermogenesis. Diabetes 53, 577-584 (2004).
    • (2004) Diabetes , vol.53 , pp. 577-584
    • Christoffolete, M.A.1
  • 7
    • 35648985719 scopus 로고    scopus 로고
    • Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor ? 1
    • Sjögren, M. et al. Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor ? 1. EMBO J. 26, 4535-4545 (2007).
    • (2007) EMBO J , vol.26 , pp. 4535-4545
    • Sjögren, M.1
  • 8
    • 84885051231 scopus 로고    scopus 로고
    • Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor 1
    • Warner, A. et al. Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor ? 1. Proc. Natl. Acad. Sci. USA 110, 16241-16246 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 16241-16246
    • Warner, A.1
  • 9
    • 63849333719 scopus 로고    scopus 로고
    • T3 and the thyroid hormone beta-receptor agonist GC-1 differentially affect metabolic capacity and oxidative damage in rat tissues
    • Venditti, P. et al. T3 and the thyroid hormone beta-receptor agonist GC-1 differentially affect metabolic capacity and oxidative damage in rat tissues. J. Exp. Biol. 212, 986-993 (2009).
    • (2009) J. Exp. Biol , vol.212 , pp. 986-993
    • Venditti, P.1
  • 10
    • 77952555444 scopus 로고    scopus 로고
    • The TRbeta-selective agonist, GC-1, stimulates mitochondrial oxidative processes to a lesser extent than triiodothyronine
    • Venditti, P. et al. The TRbeta-selective agonist, GC-1, stimulates mitochondrial oxidative processes to a lesser extent than triiodothyronine. J. Endocrinol. 205, 279-289 (2010).
    • (2010) J. Endocrinol , vol.205 , pp. 279-289
    • Venditti, P.1
  • 11
    • 0020509014 scopus 로고
    • Adrenergic activation of triiodothyronine production in brown adipose tissue
    • Silva, J. E., Larsen, P. R. Adrenergic activation of triiodothyronine production in brown adipose tissue. Nature 305, 712-713 (1983).
    • (1983) Nature , vol.305 , pp. 712-713
    • Silva, J.E.1    Larsen, P.R.2
  • 12
    • 0022366443 scopus 로고
    • Potential of brown adipose tissue type II thyroxine 5?-deiodinase as a local and systemic source of triiodothyronine in rats
    • Silva, J. E., Larsen, P. R. Potential of brown adipose tissue type II thyroxine 5?-deiodinase as a local and systemic source of triiodothyronine in rats. J. Clin. Invest. 76, 2296-2305 (1985).
    • (1985) J. Clin. Invest , vol.76 , pp. 2296-2305
    • Silva, J.E.1    Larsen, P.R.2
  • 13
    • 0032929068 scopus 로고    scopus 로고
    • 35, 3-Triiodothyronine actively stimulates UCP in brown fat under minimal sympathetic activity
    • Branco, M., Ribeiro, M., Negraõ, N., Bianco, A. C. 3, 5, 3?-Triiodothyronine actively stimulates UCP in brown fat under minimal sympathetic activity. Am. J. Physiol.-Endocrinol. Metab. 276, E179-E187 (1999).
    • (1999) Am. J. Physiol.-Endocrinol. Metab , vol.276 , pp. E179-E187
    • Branco, M.1    Ribeiro, M.2    Negraõ, N.3    Bianco, A.C.4
  • 14
    • 77956431307 scopus 로고    scopus 로고
    • Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
    • Lopez, M. et al. Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. Nat. Med. 16, 1001-1008 (2010).
    • (2010) Nat. Med , vol.16 , pp. 1001-1008
    • Lopez, M.1
  • 16
    • 0027051199 scopus 로고
    • Occurrence of brown adipocytes in rat white adipose tissue: Molecular and morphological characterization
    • Cousin, B. et al. Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization. J. Cell Sci. 103 (Pt 4), 931-942 (1992).
    • (1992) J. Cell Sci , vol.103 , pp. 931-942
    • Cousin, B.1
  • 17
    • 25144489034 scopus 로고    scopus 로고
    • Metabolic and cellular plasticity in white adipose tissue I: Effects of beta3-adrenergic receptor activation
    • Granneman, J. G., Li, P., Zhu, Z., Lu, Y. Metabolic and cellular plasticity in white adipose tissue I: effects of beta3-adrenergic receptor activation. Am. J. Physiol. Endocrinol. Metab. 289, E608-616 (2005).
    • (2005) Am. J. Physiol. Endocrinol. Metab , vol.289 , pp. E608-616
    • Granneman, J.G.1    Li, P.2    Zhu, Z.3    Lu, Y.4
  • 18
    • 0031011161 scopus 로고    scopus 로고
    • Appearance of brown adipocytes in white adipose tissue during CL 316, 243-induced reversal of obesity and diabetes in Zucker fa/fa rats
    • Ghorbani, M., Himms-Hagen, J. Appearance of brown adipocytes in white adipose tissue during CL 316, 243-induced reversal of obesity and diabetes in Zucker fa/fa rats. Int. J. Obes. Relat. Metab. Disord. J. Int. Assoc. Study Obes. 21, 465-475 (1997).
    • (1997) Int. J. Obes. Relat. Metab. Disord. J. Int. Assoc. Study Obes , vol.21 , pp. 465-475
    • Ghorbani, M.1    Himms-Hagen, J.2
  • 19
    • 0033825933 scopus 로고    scopus 로고
    • Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes
    • Himms-Hagen, J. et al. Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes. Am. J. Physiol. Cell Physiol. 279, C670-681 (2000).
    • (2000) Am. J. Physiol. Cell Physiol , vol.279 , pp. C670-681
    • Himms-Hagen, J.1
  • 20
    • 77950226740 scopus 로고    scopus 로고
    • Chronic Peroxisome Proliferator-activated Receptor (PPAR) Activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent ucp1-containing adipocytes molecularly distinct from classic brown adipocytes
    • Petrovic, N. et al. Chronic Peroxisome Proliferator-activated Receptor ? (PPAR? ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes. J. Biol. Chem. 285, 7153-7164 (2010).
    • (2010) J. Biol. Chem , vol.285 , pp. 7153-7164
    • Petrovic, N.1
  • 21
    • 84878525220 scopus 로고    scopus 로고
    • Bi-Directional interconversion of brite and white adipocytes
    • Rosenwald, M., Perdikari, A., Rülicke, T., Wolfrum, C. Bi-directional interconversion of brite and white adipocytes. Nat. Cell Biol. 15, 659-667 (2013).
    • (2013) Nat. Cell Biol , vol.15 , pp. 659-667
    • Rosenwald, M.1    Perdikari, A.2    Rülicke, T.3    Wolfrum, C.4
  • 22
    • 84855335544 scopus 로고    scopus 로고
    • Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes
    • Lee, J.-Y. et al. Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes. Am. J. Physiol. Cell Physiol. 302, C463-472 (2012).
    • (2012) Am. J. Physiol. Cell Physiol , vol.302 , pp. C463-472
    • Lee, J.-Y.1
  • 23
    • 34247344167 scopus 로고    scopus 로고
    • Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats
    • Villicev, C. M. et al. Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats. J. Endocrinol. 193, 21-29 (2007).
    • (2007) J. Endocrinol , vol.193 , pp. 21-29
    • Villicev, C.M.1
  • 24
    • 84952871381 scopus 로고    scopus 로고
    • Pharmacological activation of thyroid hormone receptors elicits a functional conversion of white to brown fat
    • Lin, J. Z. et al. Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat. Cell Rep. 13, 1528-1537 (2015).
    • (2015) Cell Rep , vol.13 , pp. 1528-1537
    • Lin, J.Z.1
  • 25
    • 84975745616 scopus 로고    scopus 로고
    • Essential role of UCP1 modulating the central effects of thyroid hormones on energy balance
    • Alvarez-Crespo, M. et al. Essential role of UCP1 modulating the central effects of thyroid hormones on energy balance. Mol. Metab. 5, 271-282 (2016).
    • (2016) Mol. Metab , vol.5 , pp. 271-282
    • Alvarez-Crespo, M.1
  • 26
    • 84946746576 scopus 로고    scopus 로고
    • Liver X receptor controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue
    • Miao, Y. et al. Liver X receptor ? controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue. Proc. Natl. Acad. Sci. 112, 14006-14011 (2015).
    • (2015) Proc. Natl. Acad. Sci , vol.112 , pp. 14006-14011
    • Miao, Y.1
  • 27
    • 75149193049 scopus 로고    scopus 로고
    • Thyroid hormone induced brown adipose tissue and amelioration of diabetes in a patient with extreme insulin resistance
    • Skarulis, M. C. et al. Thyroid Hormone Induced Brown Adipose Tissue and Amelioration of Diabetes in a Patient with Extreme Insulin Resistance. J. Clin. Endocrinol. Metab. 95, 256-262 (2010).
    • (2010) J. Clin. Endocrinol. Metab , vol.95 , pp. 256-262
    • Skarulis, M.C.1
  • 28
    • 84856970831 scopus 로고    scopus 로고
    • Zfp423 Expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells
    • Gupta, R. K. et al. Zfp423 Expression Identifies Committed Preadipocytes and Localizes to Adipose Endothelial and Perivascular Cells. Cell Metab. 15, 230-239 (2012).
    • (2012) Cell Metab , vol.15 , pp. 230-239
    • Gupta, R.K.1
  • 29
    • 77950081353 scopus 로고    scopus 로고
    • Transcriptional control of preadipocyte determination by Zfp423
    • Gupta, R. K. et al. Transcriptional control of preadipocyte determination by Zfp423. Nature 464, 619-623 (2010).
    • (2010) Nature , vol.464 , pp. 619-623
    • Gupta, R.K.1
  • 31
    • 0028951399 scopus 로고
    • Catecholaminergic innervation of white adipose tissue in Siberian hamsters
    • Youngstrom, T. G., Bartness, T. J. Catecholaminergic innervation of white adipose tissue in Siberian hamsters. Am. J. Physiol. 268, R744-751 (1995).
    • (1995) Am. J. Physiol , vol.268 , pp. R744-751
    • Youngstrom, T.G.1    Bartness, T.J.2
  • 32
    • 84913586856 scopus 로고    scopus 로고
    • The browning of white adipose tissue: Some burning issues
    • Nedergaard, J., Cannon, B. The browning of white adipose tissue: some burning issues. Cell Metab. 20, 396-407 (2014).
    • (2014) Cell Metab , vol.20 , pp. 396-407
    • Nedergaard, J.1    Cannon, B.2
  • 33
    • 0035185505 scopus 로고    scopus 로고
    • The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue
    • de Jesus, L. A. et al. The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J. Clin. Invest. 108, 1379-1385 (2001).
    • (2001) J. Clin. Invest , vol.108 , pp. 1379-1385
    • De Jesus, L.A.1
  • 34
    • 84875367849 scopus 로고    scopus 로고
    • Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat
    • Schulz, T. J. et al. Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature 495, 379-383 (2013).
    • (2013) Nature , vol.495 , pp. 379-383
    • Schulz, T.J.1
  • 36
    • 0031016659 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the beta 1-adrenergic receptor in adipose tissue are resistant to obesity
    • Soloveva, V., Graves, R. A., Rasenick, M. M., Spiegelman, B. M., Ross, S. R. Transgenic mice overexpressing the beta 1-adrenergic receptor in adipose tissue are resistant to obesity. Mol. Endocrinol. Baltim. Md 11, 27-38 (1997).
    • (1997) Mol. Endocrinol. Baltim. Md , vol.11 , pp. 27-38
    • Soloveva, V.1    Graves, R.A.2    Rasenick, M.M.3    Spiegelman, B.M.4    Ross, S.R.5
  • 37
    • 77956431307 scopus 로고    scopus 로고
    • Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
    • López, M. et al. Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. Nat. Med. 16, 1001-1008 (2010).
    • (2010) Nat. Med , vol.16 , pp. 1001-1008
    • López, M.1
  • 38
    • 84892151578 scopus 로고    scopus 로고
    • American thyroid association guide to investigating thyroid hormone economy and action in rodent and cell models
    • Bianco, A. C. et al. American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models. Thyroid 24, 88-168 (2014).
    • (2014) Thyroid , vol.24 , pp. 88-168
    • Bianco, A.C.1
  • 39
    • 84873518501 scopus 로고    scopus 로고
    • Adaptive thermogenesis in adipocytes: Is beige the new brown?
    • Wu, J., Cohen, P., Spiegelman, B. M. Adaptive thermogenesis in adipocytes: Is beige the new brown? Genes Dev. 27, 234-250 (2013).
    • (2013) Genes Dev , vol.27 , pp. 234-250
    • Wu, J.1    Cohen, P.2    Spiegelman, B.M.3
  • 40
    • 84865958500 scopus 로고    scopus 로고
    • Thermal control of brown adipose tissue in 18F-FDG PET
    • Skillen, A., Currie, G. M., Wheat, J. M. Thermal control of brown adipose tissue in 18F-FDG PET. J. Nucl. Med. Technol. 40, 99-103 (2012).
    • (2012) J. Nucl. Med. Technol , vol.40 , pp. 99-103
    • Skillen, A.1    Currie, G.M.2    Wheat, J.M.3
  • 41
    • 84907553425 scopus 로고    scopus 로고
    • Liver-restricted Repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice
    • Kern, M. et al. Liver-restricted Repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice. Diabetes 63, 3295-3309 (2014).
    • (2014) Diabetes , vol.63 , pp. 3295-3309
    • Kern, M.1
  • 42
    • 77956717834 scopus 로고    scopus 로고
    • Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes
    • Ruschke, K. et al. Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes. Biochem. Biophys. Res. Commun. 400, 246-251 (2010).
    • (2010) Biochem. Biophys. Res. Commun , vol.400 , pp. 246-251
    • Ruschke, K.1
  • 43
    • 0018974004 scopus 로고
    • Iodothyronine 5?-deiodinase from rat kidney: Substrate specificity and the 5?-deiodination of reverse triiodothyronine
    • Leonard, J. L., Rosenberg, I. N. Iodothyronine 5?-deiodinase from rat kidney: substrate specificity and the 5?-deiodination of reverse triiodothyronine. Endocrinology 107, 1376-1383 (1980).
    • (1980) Endocrinology , vol.107 , pp. 1376-1383
    • Leonard, J.L.1    Rosenberg, I.N.2
  • 44
    • 84946039854 scopus 로고    scopus 로고
    • Biosynthesis of 3-Iodothyronamine from t4 in murine intestinal tissue
    • Hoefig, C. S. et al. Biosynthesis of 3-Iodothyronamine From T4 in Murine Intestinal Tissue. Endocrinology 156, 4356-4364 (2015).
    • (2015) Endocrinology , vol.156 , pp. 4356-4364
    • Hoefig, C.S.1
  • 45
    • 81255201252 scopus 로고    scopus 로고
    • Dissecting molecular events in thyroid neoplasia provides evidence for distinct evolution of follicular thyroid adenoma and carcinoma
    • Krause, K. et al. Dissecting molecular events in thyroid neoplasia provides evidence for distinct evolution of follicular thyroid adenoma and carcinoma. Am. J. Pathol. 179, 3066-3074 (2011).
    • (2011) Am. J. Pathol , vol.179 , pp. 3066-3074
    • Krause, K.1
  • 46
    • 42049095508 scopus 로고    scopus 로고
    • TFF3-Based candidate gene discrimination of benign and malignant thyroid tumors in a region with borderline iodine deficiency
    • Krause, K. et al. TFF3-based candidate gene discrimination of benign and malignant thyroid tumors in a region with borderline iodine deficiency. J. Clin. Endocrinol. Metab. 93, 1390-1393 (2008).
    • (2008) J. Clin. Endocrinol. Metab , vol.93 , pp. 1390-1393
    • Krause, K.1
  • 47
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak, K. J., Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods San Diego Calif 25, 402-408 (2001).
    • (2001) Methods San Diego Calif , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


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