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Volumn 13, Issue 8, 2015, Pages 1528-1537

Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat

Author keywords

[No Author keywords available]

Indexed keywords

EPROTIROME; HORMONE RECEPTOR STIMULATING AGENT; PROPRANOLOL; SOBETIROME; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 84952871381     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.10.022     Document Type: Article
Times cited : (97)

References (31)
  • 1
    • 0026565461 scopus 로고
    • Brown adipose tissue thermogenesis in T3-treated rats
    • Abelenda M., Puerta M.L. Brown adipose tissue thermogenesis in T3-treated rats. Horm. Metab. Res. 1992, 24:60-62.
    • (1992) Horm. Metab. Res. , vol.24 , pp. 60-62
    • Abelenda, M.1    Puerta, M.L.2
  • 2
    • 47149118684 scopus 로고    scopus 로고
    • The discovery of drugs for obesity, the metabolic effects of leptin and variable receptor pharmacology: perspectives from beta3-adrenoceptor agonists
    • Arch J.R.S. The discovery of drugs for obesity, the metabolic effects of leptin and variable receptor pharmacology: perspectives from beta3-adrenoceptor agonists. Naunyn Schmiedebergs Arch. Pharmacol. 2008, 378:225-240.
    • (2008) Naunyn Schmiedebergs Arch. Pharmacol. , vol.378 , pp. 225-240
    • Arch, J.R.S.1
  • 3
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose tissue: function and physiological significance
    • Cannon B., Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol. Rev. 2004, 84:277-359.
    • (2004) Physiol. Rev. , vol.84 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 4
    • 0035235089 scopus 로고    scopus 로고
    • Morphologic techniques for the study of brown adipose tissue and white adipose tissue
    • Cinti S., Zingaretti M.C., Cancello R., Ceresi E., Ferrara P. Morphologic techniques for the study of brown adipose tissue and white adipose tissue. Methods Mol. Biol. 2001, 155:21-51.
    • (2001) Methods Mol. Biol. , vol.155 , pp. 21-51
    • Cinti, S.1    Zingaretti, M.C.2    Cancello, R.3    Ceresi, E.4    Ferrara, P.5
  • 5
    • 0027051199 scopus 로고
    • Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization
    • Cousin B., Cinti S., Morroni M., Raimbault S., Ricquier D., Pénicaud L., Casteilla L. Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization. J. Cell Sci. 1992, 103:931-942.
    • (1992) J. Cell Sci. , vol.103 , pp. 931-942
    • Cousin, B.1    Cinti, S.2    Morroni, M.3    Raimbault, S.4    Ricquier, D.5    Pénicaud, L.6    Casteilla, L.7
  • 6
    • 84904177872 scopus 로고    scopus 로고
    • The chemical uncoupler 2,4-dinitrophenol (DNP) protects against diet-induced obesity and improves energy homeostasis in mice at thermoneutrality
    • Goldgof M., Xiao C., Chanturiya T., Jou W., Gavrilova O., Reitman M.L. The chemical uncoupler 2,4-dinitrophenol (DNP) protects against diet-induced obesity and improves energy homeostasis in mice at thermoneutrality. J. Biol. Chem. 2014, 289:19341-19350.
    • (2014) J. Biol. Chem. , vol.289 , pp. 19341-19350
    • Goldgof, M.1    Xiao, C.2    Chanturiya, T.3    Jou, W.4    Gavrilova, O.5    Reitman, M.L.6
  • 7
    • 1642505721 scopus 로고    scopus 로고
    • Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine
    • Grover G.J., Egan D.M., Sleph P.G., Beehler B.C., Chiellini G., Nguyen N.H., Baxter J.D., Scanlan T.S. Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine. Endocrinology 2004, 145:1656-1661.
    • (2004) Endocrinology , vol.145 , pp. 1656-1661
    • Grover, G.J.1    Egan, D.M.2    Sleph, P.G.3    Beehler, B.C.4    Chiellini, G.5    Nguyen, N.H.6    Baxter, J.D.7    Scanlan, T.S.8
  • 8
    • 0032528169 scopus 로고    scopus 로고
    • Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity
    • Guerra C., Koza R.A., Yamashita H., Walsh K., Kozak L.P. Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. J. Clin. Invest. 1998, 102:412-420.
    • (1998) J. Clin. Invest. , vol.102 , pp. 412-420
    • Guerra, C.1    Koza, R.A.2    Yamashita, H.3    Walsh, K.4    Kozak, L.P.5
  • 10
    • 84887431711 scopus 로고    scopus 로고
    • Brown and beige fat: development, function and therapeutic potential
    • Harms M., Seale P. Brown and beige fat: development, function and therapeutic potential. Nat. Med. 2013, 19:1252-1263.
    • (2013) Nat. Med. , vol.19 , pp. 1252-1263
    • Harms, M.1    Seale, P.2
  • 14
    • 84927551485 scopus 로고    scopus 로고
    • The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice
    • Martagón A.J., Lin J.Z., Cimini S.L., Webb P., Phillips K.J. The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice. PLoS ONE 2015, 10:e0122987.
    • (2015) PLoS ONE , vol.10 , pp. e0122987
    • Martagón, A.J.1    Lin, J.Z.2    Cimini, S.L.3    Webb, P.4    Phillips, K.J.5
  • 15
    • 77957279363 scopus 로고    scopus 로고
    • The T3 receptor beta1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes
    • Martinez de Mena R., Scanlan T.S., Obregon M.-J. The T3 receptor beta1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes. Endocrinology 2010, 151:5074-5083.
    • (2010) Endocrinology , vol.151 , pp. 5074-5083
    • Martinez de Mena, R.1    Scanlan, T.S.2    Obregon, M.-J.3
  • 18
    • 84913586856 scopus 로고    scopus 로고
    • The browning of white adipose tissue: some burning issues
    • Nedergaard J., Cannon B. The browning of white adipose tissue: some burning issues. Cell Metab. 2014, 20:396-407.
    • (2014) Cell Metab. , vol.20 , pp. 396-407
    • Nedergaard, J.1    Cannon, B.2
  • 21
    • 0017758504 scopus 로고
    • Studies on hypothermia and thyroid function in the obese (ob/ob) mouse
    • Ohtake M., Bray G.A., Azukizawa M. Studies on hypothermia and thyroid function in the obese (ob/ob) mouse. Am. J. Physiol. 1977, 233:R110-R115.
    • (1977) Am. J. Physiol. , vol.233 , pp. R110-R115
    • Ohtake, M.1    Bray, G.A.2    Azukizawa, M.3
  • 22
    • 0022976984 scopus 로고
    • Thyroid hormone-catecholamine interrelationship during cold acclimation in rats. Compensatory role of catecholamine for altered thyroid states
    • Sato T., Imura E., Murata A., Igarashi N. Thyroid hormone-catecholamine interrelationship during cold acclimation in rats. Compensatory role of catecholamine for altered thyroid states. Acta Endocrinol. 1986, 113:536-542.
    • (1986) Acta Endocrinol. , vol.113 , pp. 536-542
    • Sato, T.1    Imura, E.2    Murata, A.3    Igarashi, N.4
  • 23
    • 84961290714 scopus 로고    scopus 로고
    • Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis
    • Sidossis L., Kajimura S. Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis. J. Clin. Invest. 2015, 125:478-486.
    • (2015) J. Clin. Invest. , vol.125 , pp. 478-486
    • Sidossis, L.1    Kajimura, S.2
  • 24
    • 0029561581 scopus 로고
    • Thyroid hormone control of thermogenesis and energy balance
    • Silva J.E. Thyroid hormone control of thermogenesis and energy balance. Thyroid 1995, 5:481-492.
    • (1995) Thyroid , vol.5 , pp. 481-492
    • Silva, J.E.1
  • 25
    • 0344738018 scopus 로고    scopus 로고
    • Conversion from white to brown adipocytes: a strategy for the control of fat mass?
    • Tiraby C., Langin D. Conversion from white to brown adipocytes: a strategy for the control of fat mass?. Trends Endocrinol. Metab. 2003, 14:439-441.
    • (2003) Trends Endocrinol. Metab. , vol.14 , pp. 439-441
    • Tiraby, C.1    Langin, D.2
  • 26
    • 0034890103 scopus 로고    scopus 로고
    • Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ
    • Trayhurn P., Beattie J.H. Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc. Nutr. Soc. 2001, 60:329-339.
    • (2001) Proc. Nutr. Soc. , vol.60 , pp. 329-339
    • Trayhurn, P.1    Beattie, J.H.2
  • 27
    • 33845969892 scopus 로고    scopus 로고
    • UCP1-independent thermogenesis in white adipose tissue of cold-acclimated Ucp1-/- mice
    • Ukropec J., Anunciado R.P., Ravussin Y., Hulver M.W., Kozak L.P. UCP1-independent thermogenesis in white adipose tissue of cold-acclimated Ucp1-/- mice. J. Biol. Chem. 2006, 281:31894-31908.
    • (2006) J. Biol. Chem. , vol.281 , pp. 31894-31908
    • Ukropec, J.1    Anunciado, R.P.2    Ravussin, Y.3    Hulver, M.W.4    Kozak, L.P.5
  • 28
    • 78650916392 scopus 로고    scopus 로고
    • Minireview: thyroid hormone transporters: the knowns and the unknowns
    • Visser W.E., Friesema E.C.H., Visser T.J. Minireview: thyroid hormone transporters: the knowns and the unknowns. Mol. Endocrinol. 2011, 25:1-14.
    • (2011) Mol. Endocrinol. , vol.25 , pp. 1-14
    • Visser, W.E.1    Friesema, E.C.H.2    Visser, T.J.3
  • 29
    • 84887502374 scopus 로고    scopus 로고
    • Tracking adipogenesis during white adipose tissue development, expansion and regeneration
    • Wang Q.A., Tao C., Gupta R.K., Scherer P.E. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nat. Med. 2013, 19:1338-1344.
    • (2013) Nat. Med. , vol.19 , pp. 1338-1344
    • Wang, Q.A.1    Tao, C.2    Gupta, R.K.3    Scherer, P.E.4
  • 30
    • 84903471139 scopus 로고    scopus 로고
    • Triiodothyronine regulates distribution of thyroid hormone receptors by activating AMP-activated protein kinase in 3T3-L1 adipocytes and induces uncoupling protein-1 expression
    • Wang C.-Z., Wei D., Guan M.P., Xue Y.M. Triiodothyronine regulates distribution of thyroid hormone receptors by activating AMP-activated protein kinase in 3T3-L1 adipocytes and induces uncoupling protein-1 expression. Mol. Cell. Biochem. 2014, 393:247-254.
    • (2014) Mol. Cell. Biochem. , vol.393 , pp. 247-254
    • Wang, C.-Z.1    Wei, D.2    Guan, M.P.3    Xue, Y.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.