Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

eLife

Volumn 5, Issue NOVEMBER2016, 2016, Pages

  Heo, Su Jin ^a,b   Driscoll, Tristan P ^a,b   Thorpe, Stephen D ^c   Nerurkar, Nandan L ^d   Baker, Brendon M ^e,f   Yang, Michael T ^e   Chen, Christopher S ^e,f   Lee, David A ^c   Mauck, Robert L ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d HARVARD MEDICAL SCHOOL   (United States)

^e Boston University   (United States)

^f HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MOLECULAR SCAFFOLD; POLYCAPROLACTONE; STRUCTURAL PROTEIN; TRANSFORMING GROWTH FACTOR BETA3; TRICHOSTATIN A; HETEROCHROMATIN; LAMIN A;

ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL ADHESION; CELL DIFFERENTIATION; CELL ISOLATION; CELL MIGRATION; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOARCHITECTURE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HETEROCHROMATIN; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MUSCLE CONTRACTILITY; NONHUMAN; RADIOIMMUNOPRECIPITATION; REAL TIME POLYMERASE CHAIN REACTION; SENSITIZATION; SIGNAL TRANSDUCTION; TOTAL ARTHROPLASTY; ANIMAL; BIOPHYSICS; BOVINE; CELL CULTURE; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY;

ANIMALS; BIOPHYSICAL PHENOMENA; CATTLE; CELL DIFFERENTIATION; CELL NUCLEUS; CELLS, CULTURED; HETEROCHROMATIN; HUMANS; LAMIN TYPE A; MESENCHYMAL STROMAL CELLS;

EID: 85005976103     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.18207     Document Type: Article

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