Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion

Cell Metabolism

Volumn 24, Issue 6, 2016, Pages 783-794

  Jakulj, Lily ^a   van Dijk, Theo H ^b   de Boer, Jan Freark ^b   Kootte, Ruud S ^a   Schonewille, Marleen ^b   Paalvast, Yared ^b   Boer, Theo ^b   Bloks, Vincent W ^b   Boverhof, Renze ^b   Nieuwdorp, Max ^a   Beuers, Ulrich H W ^a   Stroes, Erik S G ^a   Groen, Albert K ^a,b  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

bile salt; biliary cholesterol; reverse cholesterol transport; transintestinal cholesterol transport

Indexed keywords

ABC TRANSPORTER G5; ABC TRANSPORTER G8; BILE SALT; CHOLESTEROL; CHYLOMICRON REMNANT; EZETIMIBE; ABCG8 PROTEIN, MOUSE; BILE ACID; LIPOPROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FECES; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; INTESTINAL SECRETION; MALE; NONHUMAN; PRIORITY JOURNAL; STEROL EXCRETION; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; FEMALE; INTESTINE; KINETICS; METABOLISM; MIDDLE AGED; TRANSPORT AT THE CELLULAR LEVEL;

ADULT; ANIMALS; ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G, MEMBER 8; BILE; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT; CHOLESTEROL; EZETIMIBE; FECES; FEMALE; HUMANS; INTESTINES; KINETICS; LIPOPROTEINS; MALE; MICE, INBRED C57BL; MIDDLE AGED;

EID: 85004109128     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.10.001     Document Type: Article

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