메뉴 건너뛰기




Volumn 25, Issue 24, 2016, Pages 1863-1873

Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy

Author keywords

CD34; HSC; human immunology; human immunotherapy; humanized BLT mice; propagating

Indexed keywords

CD34 ANTIGEN; ENHANCED GREEN FLUORESCENT PROTEIN; HLA A2 ANTIGEN;

EID: 85004073500     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2016.0193     Document Type: Article
Times cited : (35)

References (40)
  • 1
    • 84867898654 scopus 로고    scopus 로고
    • Humanized mice for immune system investigation: Progress, promise and challenges
    • Shultz LD, MA Brehm, JV Garcia-Martinez and DL Greiner. (2012). Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol 12:786-798.
    • (2012) Nat Rev Immunol , vol.12 , pp. 786-798
    • Shultz, L.D.1    Brehm, M.A.2    Garcia-Martinez, J.V.3    Greiner, D.L.4
  • 4
    • 77649232760 scopus 로고    scopus 로고
    • Parameters for establishing humanized mouse models to study human immunity: Analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation
    • Brehm MA, A Cuthbert, C Yang, DM Miller, P DiIorio, J Laning, L Burzenski, B Gott, O Foreman, et al. (2010). Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation. Clin Immunol 135:84-98.
    • (2010) Clin Immunol , vol.135 , pp. 84-98
    • Brehm, M.A.1    Cuthbert, A.2    Yang, C.3    Miller, D.M.4    Diiorio, P.5    Laning, J.6    Burzenski, L.7    Gott, B.8    Foreman, O.9
  • 6
    • 0023734130 scopus 로고
    • Transfer of a functional human immune system to mice with severe combined immunodeficiency
    • Mosier DE, RJ Gulizia, SM Baird and DB Wilson. (1988). Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 335:256-259.
    • (1988) Nature , vol.335 , pp. 256-259
    • De, M.1    Gulizia, R.J.2    Baird, S.M.3    Wilson, D.B.4
  • 9
    • 0023753744 scopus 로고
    • The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
    • McCune JM, R Namikawa, H Kaneshima, LD Shultz, M Lieberman and IL Weissman. (1988). The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 241:1632-1639.
    • (1988) Science , vol.241 , pp. 1632-1639
    • McCune, J.M.1    Namikawa, R.2    Kaneshima, H.3    Shultz, L.D.4    Lieberman, M.5    Weissman, I.L.6
  • 11
    • 33745959565 scopus 로고    scopus 로고
    • Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation
    • Lan P, N Tonomura, A Shimizu, S Wang and YG Yang. (2006). Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation. Blood 108:487-492.
    • (2006) Blood , vol.108 , pp. 487-492
    • Lan, P.1    Tonomura, N.2    Shimizu, A.3    Wang, S.4    Yang, Y.G.5
  • 13
    • 67650410026 scopus 로고    scopus 로고
    • Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice
    • Brainard DM, E Seung, N Frahm, A Cariappa, CC Bailey, WK Hart, HS Shin, SF Brooks, HL Knight, et al. (2009). Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice. J Virol 83:7305-7321.
    • (2009) J Virol , vol.83 , pp. 7305-7321
    • Brainard, D.M.1    Seung, E.2    Frahm, N.3    Cariappa, A.4    Bailey, C.C.5    Hart, W.K.6    Shin, H.S.7    Brooks, S.F.8    Knight, H.L.9
  • 14
    • 84939783318 scopus 로고    scopus 로고
    • Studies of retroviral infection in humanized mice
    • Marsden MD and JA Zack. (2015). Studies of retroviral infection in humanized mice. Virology 479-480:297-309.
    • (2015) Virology , vol.479-480 , pp. 297-309
    • Marsden, M.D.1    Zack, J.A.2
  • 15
    • 84931266151 scopus 로고    scopus 로고
    • BLT humanized mice as a small animal model of HIV infection
    • Karpel ME, CL Boutwell and TM Allen. (2015). BLT humanized mice as a small animal model of HIV infection. Curr Opin Virol 13:75-80.
    • (2015) Curr Opin Virol , vol.13 , pp. 75-80
    • Karpel, M.E.1    Boutwell, C.L.2    Allen, T.M.3
  • 16
    • 84956928814 scopus 로고    scopus 로고
    • Vivo platforms for analysis of HIV persistence and eradication
    • Garcia JV. (2016). In vivo platforms for analysis of HIV persistence and eradication. J Clin Invest 126:424-431.
    • (2016) J Clin Invest , vol.126 , pp. 424-431
    • Garcia, J.V.1
  • 17
    • 84891642296 scopus 로고    scopus 로고
    • Recent advances in humanized mice: Accelerating the development of an HIV vaccine
    • Tager AM, M Pensiero and TM Allen. (2013). Recent advances in humanized mice: accelerating the development of an HIV vaccine. J Infect Dis 208 Suppl 2:S121-S124.
    • (2013) J Infect Dis 208 Suppl , vol.2 , pp. S121-S124
    • Tager, A.M.1    Pensiero, M.2    Allen, T.M.3
  • 18
    • 77949885010 scopus 로고    scopus 로고
    • A highly efficient short hairpin RNA potently downregulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model
    • Shimizu S, P Hong, B Arumugam, L Pokomo, J Boyer, N Koizumi, P Kittipongdaja, A Chen, G Bristol, et al. (2010). A highly efficient short hairpin RNA potently downregulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model. Blood 115:1534-1544.
    • (2010) Blood , vol.115 , pp. 1534-1544
    • Shimizu, S.1    Hong, P.2    Arumugam, B.3    Pokomo, L.4    Boyer, J.5    Koizumi, N.6    Kittipongdaja, P.7    Chen, A.8    Bristol, G.9
  • 20
    • 84895427883 scopus 로고    scopus 로고
    • Preclinical demonstration of lentiviral vectormediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency
    • Carbonaro DA, L Zhang, X Jin, C Montiel-Equihua, S Geiger, M Carmo, A Cooper, L Fairbanks, ML Kaufman, et al. (2014). Preclinical demonstration of lentiviral vectormediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency. Mol Ther 22:607-622.
    • (2014) Mol Ther , vol.22 , pp. 607-622
    • Carbonaro, D.A.1    Zhang, L.2    Jin, X.3    Montiel-Equihua, C.4    Geiger, S.5    Carmo, M.6    Cooper, A.7    Fairbanks, L.8    Kaufman, M.L.9
  • 24
    • 84877015451 scopus 로고    scopus 로고
    • Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells
    • Giannoni F, CL Hardee, J Wherley, E Gschweng, S Senadheera, ML Kaufman, R Chan, I Bahner, V Gersuk, et al. (2013). Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells. Mol Ther 21:1044-1054.
    • (2013) Mol Ther , vol.21 , pp. 1044-1054
    • Giannoni, F.1    Hardee, C.L.2    Wherley, J.3    Gschweng, E.4    Senadheera, S.5    Kaufman, M.L.6    Chan, R.7    Bahner, I.8    Gersuk, V.9
  • 26
    • 24144480562 scopus 로고    scopus 로고
    • Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
    • Watanabe N, YH Wang, HK Lee, T Ito, YH Wang, W Cao and YJ Liu. (2005). Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus. Nature 436:1181-1185.
    • (2005) Nature , vol.436 , pp. 1181-1185
    • Watanabe, N.1    Wang, Y.H.2    Lee, H.K.3    Ito, T.4    Wang, Y.H.5    Cao, W.6    Liu, Y.J.7
  • 27
    • 0036779662 scopus 로고    scopus 로고
    • Development of alphabeta T cells in the human thymus
    • Spits H. (2002). Development of alphabeta T cells in the human thymus. Nat Rev Immunol 2:760-772.
    • (2002) Nat Rev Immunol , vol.2 , pp. 760-772
    • Spits, H.1
  • 28
    • 33947124454 scopus 로고    scopus 로고
    • The HLA system: Genetics, immunology, clinical testing, and clinical implications
    • Choo SY. (2007). The HLA system: genetics, immunology, clinical testing, and clinical implications. Yonsei Med J 48:11-23.
    • (2007) Yonsei Med J , vol.48 , pp. 11-23
    • Choo, S.Y.1
  • 31
    • 84890192292 scopus 로고    scopus 로고
    • Hematopoietic stem cells for cancer immunotherapy
    • Gschweng E, S De Oliveira and DB Kohn. (2014). Hematopoietic stem cells for cancer immunotherapy. Immunol Rev 257:237-249.
    • (2014) Immunol Rev , vol.257 , pp. 237-249
    • Gschweng, E.1    De Oliveira, S.2    Kohn, D.B.3
  • 32
    • 84962739516 scopus 로고    scopus 로고
    • Gene Therapy for the Treatment of Primary Immune Deficiencies
    • Kuo CY and DB Kohn. (2016). Gene Therapy for the Treatment of Primary Immune Deficiencies. Curr Allergy Asthma Rep 16:39.
    • (2016) Curr Allergy Asthma Rep , vol.16 , pp. 39
    • Kuo, C.Y.1    Kohn, D.B.2
  • 33
    • 84974569561 scopus 로고    scopus 로고
    • The clinical applications of genome editing in HIV
    • Wang CX and PM Cannon. (2016). The clinical applications of genome editing in HIV. Blood 127:2546-2552.
    • (2016) Blood , vol.127 , pp. 2546-2552
    • Wang, C.X.1    Cannon, P.M.2
  • 36
    • 84883694492 scopus 로고    scopus 로고
    • Innate and Adaptive Immunity in Long-Term Non-Progression in HIV Disease
    • Zaunders J and D van Bockel. (2013). Innate and Adaptive Immunity in Long-Term Non-Progression in HIV Disease. Front Immunol 4:95.
    • (2013) Front Immunol , vol.4 , pp. 95
    • Zaunders, J.1    Van Bockel, D.2
  • 38
    • 84922541540 scopus 로고    scopus 로고
    • Nonirradiated NOD,B6.SCID Il2rgamma-/-Kit(W41/W41) (NBSGW) mice support multilineage engraftment of human hematopoietic cells
    • McIntosh BE, ME Brown, BM Duffin, JP Maufort, DT Vereide, Slukvin, II and JA Thomson. (2015). Nonirradiated NOD,B6.SCID Il2rgamma-/-Kit(W41/W41) (NBSGW) mice support multilineage engraftment of human hematopoietic cells. Stem Cell Rep 4:171-180.
    • (2015) Stem Cell Rep , vol.4 , pp. 171-180
    • McIntosh, B.E.1    Brown, M.E.2    Duffin, B.M.3    Maufort, J.P.4    Vereide, D.T.5    Slukvin, I.I.6    Thomson, J.A.7
  • 39
    • 80051988436 scopus 로고    scopus 로고
    • Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/-mice improves engraftment of human hematopoietic cells in humanized mice
    • Strowig T, A Rongvaux, C Rathinam, H Takizawa, C Borsotti, W Philbrick, EE Eynon, MG Manz and RA Flavell. (2011). Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/-mice improves engraftment of human hematopoietic cells in humanized mice. Proc Natl Acad Sci USA 108:13218-13223.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 13218-13223
    • Strowig, T.1    Rongvaux, A.2    Rathinam, C.3    Takizawa, H.4    Borsotti, C.5    Philbrick, W.6    Eynon, E.E.7    Manz, M.G.8    Flavell, R.A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.