Increase of cytotoxicity during wastewater chlorination: Impact factors and surrogates

Journal of Hazardous Materials

Volumn 324, Issue , 2017, Pages 681-690

  Du, Ye ^a   Wu, Qian Yuan ^a   Lu, Yun ^a   Hu, Hong Ying ^a,b   Yang, Yang ^a   Liu, Rui ^a   Liu, Feng ^a  

^a TSINGHUA UNIVERSITY   (China)

^b Tsinghua Berkeley Shenzhen Institute   (China)

Author keywords

AOX formation; Chlorination; Cytotoxicity; Treated wastewater; UV254

Indexed keywords

ASCORBIC ACID; BYPRODUCTS; CHLORINATION; CHLORINE; CYTOTOXICITY; MAMMALS; SODIUM COMPOUNDS;

AMMONIA CONCENTRATIONS; AOX FORMATION; DISINFECTION BYPRODUCTS; FORMATION POTENTIAL; MAMMALIAN CELLS; SODIUM THIOSULFATE; TREATED WASTEWATER; UV254;

WASTEWATER TREATMENT;

AMMONIA; ASCORBIC ACID; ASPARTATE SODIUM; CHLORINE; HYDROCHLORIC ACID; NITROGEN; SODIUM SULFATE; SODIUM THIOSULFATE;

AMMONIUM; ASCORBIC ACID; CELLS AND CELL COMPONENTS; CHLORINATION; DOSE-RESPONSE RELATIONSHIP; ESTIMATION METHOD; SURROGATE METHOD; THIOSULFATE; TOXICITY TEST; ULTRAVIOLET RADIATION; WASTEWATER;

ARTICLE; CHLORINATION; CYTOTOXICITY; NONHUMAN; SOLID PHASE EXTRACTION; ULTRAVIOLET RADIATION; WASTE; WASTE WATER; WASTE WATER MANAGEMENT; WATER SAMPLING; ANALYSIS; ANIMAL; CELL SURVIVAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; DRUG EFFECT; HALOGENATION; PROCEDURES; TOXICITY; WATER MANAGEMENT; WATER POLLUTANT;

MAMMALIA;

ANIMALS; CELL SURVIVAL; CHLORINE; CHO CELLS; CRICETULUS; HALOGENATION; WASTE WATER; WATER POLLUTANTS, CHEMICAL; WATER PURIFICATION;

EID: 85003013095     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2016.11.042     Document Type: Article

References (61)

1. [1] Sun, Y., Chen, Z., Wu, G.-X., Wu, Q.-Y., Zhang, F., Niu, Z., Hu, H.-Y., Characteristics of water quality of municipal wastewater treatment plants in China: implications for resources utilization and management. J. Clean. Prod. 131 (2016), 1–9.
2. [2] Chu, W., Gao, N., Yin, D., Krasner, S.W., Mitch, W.A., Impact of UV/H2O2 pre-oxidation on the formation of haloacetamides and other nitrogenous disinfection byproducts during chlorination. Environ. Sci. Technol. 48 (2014), 12190–12198.
3. [3] Richardson, S.D., Plewa, M.J., Wagner, E.D., Schoeny, R., DeMarini, D.M., Occurrence genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research. Mutat. Res. Rev. Mutat. 636 (2007), 178–242.
4. [4] Plewa, M.J., Wagner, E.D., Muellner, M.G., Hsu, K.M., Richardson, S.D., Comparative mammalian cell toxicity of N-DBPs and C-DBPs. Urbana, 51, 2008, 61801.
5. [5] McCarty, L.S., Borgert, C.J., Review of the toxicity of chemical mixtures: theory policy, and regulatory practice. Regul. Toxicol. Pharm. 45 (2006), 119–143.
6. [6] Tang, J.Y., Busetti, F., Charrois, J.W., Escher, B.I., Which chemicals drive biological effects in wastewater and recycled water. Water Res. 60 (2014), 289–299.
7. [7] Leusch, F.D., Khan, S.J., Laingam, S., Prochazka, E., Froscio, S., Trinh, T., Chapman, H.F., Humpage, A., Assessment of the application of bioanalytical tools as surrogate measure of chemical contaminants in recycled water. Water Res. 49 (2014), 300–315.
8. [8] Krewski, D., Andersen, M.E., Mantus, E., Zeise, L., Toxicity testing in the 21 st century: implications for human health risk assessment. Risk Anal. 29 (2009), 474–479.
9. [9] Plewa, M.J., Kargalioglu, Y., Vankerk, D., Minear, R.A., Wagner, E.D., Development of quantitative comparative cytotoxicity and genotoxicity assays for environmental hazardous chemicals. Water Sci. Technol. 42 (2000), 109–116.
10. [10] Hebert, A., Forestier, D., Lenes, D., Benanou, D., Jacob, S., Arfi, C., Lambolez, L., Levi, Y., Innovative method for prioritizing emerging disinfection by-products (DBPs) in drinking water on the basis of their potential impact on public health. Water Res. 44 (2010), 3147–3165.
11. [11] Plewa, M.J., Wagner, E.D., Jazwierska, P., Richardson, S.D., Chen, P.H., McKague, A.B., Halonitromethane drinking water disinfection byproducts: chemical characterization and mammalian cell cytotoxicity and genotoxicity. Environ. Sci. Technol. 38 (2004), 62–68.
12. [12] Jia, A., Escher, B.I., Leusch, F.D.L., Tang, J.Y.M., Prochazka, E., Dong, B., Snyder, E.M., Snyder, S.A., In vitro bioassays to evaluate complex chemical mixtures in recycled water. Water Res. 80 (2015), 1–11.
13. [13] Yang, Y., Komaki, Y., Kimura, S.-Y., Hu, H.-Y., Wagner, E.D., Mariñas, B.J., Plewa, M.J., Toxic impact of bromide and iodide on drinking water disinfected with chlorine or chloramines. Environ. Sci. Technol. 48 (2014), 12362–12369.
14. [14] Leusch, F.D., Snyder, S.A., Bioanalytical tools: half a century of application for potable reuse. Environ. Sci. Water Res. 5 (2015), 606–621.
15. [15] Escher, B.I., Allinson, M., Altenburger, R., Bain, P.A., Balaguer, P., Busch, W., Crago, J., Denslow, N.D., Dopp, E., Hilscherova, K., Humpage, A.R., Kumar, A., Grimaldi, M., Jayasinghe, B.S., Jarosova, B., Jia, A., Makarov, S., Maruya, K.A., Medvedev, A., Mehinto, A.C., Mendez, J.E., Poulson, A., Prochazka, E., Richard, J., Schifferli, A., Schlenk, D., Scholz, S., Shiraishi, F., Snyder, S., Su, G., Tang, J.Y.M., van der Burg, B., van der Linden, S.C., Werner, I., Westerheide, S.D., Wong, C.K.C., Yan, M., Yeung, B.H.Y., Zhang, X., Leusch, F.D.L., Benchmarking organic micropollutants in wastewater: recycled water and drinking water with in vitro bioassays. Environ. Sci. Technol. 48 (2014), 1940–1956.
16. [16] Yang, Y., Lu, Y., Wu, Q.-Y., Hu, H.-Y., Chen, Y.-H., Liu, W.-L., Evidence of ATP assay as an appropriate alternative of MTT assay for cytotoxicity of secondary effluents from WWTPs. Ecotoxicol. Environ. Saf. 122 (2015), 490–496.
17. [17] Lu, J., Dong, W., Ji, Y., Kong, D., Huang, Q., Natural organic matter exposed to sulfate radicals increases its potential to form halogenated disinfection byproducts. Environ. Sci. Technol. 50 (2016), 5060–5067.
18. [18] APHA, Standard Methods for the Examination of Water and Wastewater. 2005, American Public Health Association (APHA), Washington DC, USA.
19. [19] Krasner, S.W., Sclimenti, M.J., Guo, Y.-C., Hwang, C.-J., Westerhoff, P., Development of DBP and nitrosamine formation potential tests for treated wastewater, reclaimed water, and drinking water. Proceedings of the 2004 AWWA Water Quality Technology Conference, AWWA Denver, CO (2004), 2004.
20. [20] Neale, P., Farre, M.J., Day, S., Stalter, D., Tang, Y.M., Escher, B., Assessing the role of natural organic matter for disinfection by-product formation: application of bioanalytical and analytical tools. Inf. Theory Workshop ITW IEEE 35 (2013), 276–280.
21. [21] Stalter, D., Farré, M.J., Neale, P.A., Day, S., Tang, Y.M., Escher, B.I., Bioanalytical assessment of the disinfection by-product formation potential in drinking water. J. Hered. 99 (2013), 491–499.
22. [22] Liu, Q., Chen, Z., Wei, D., Du, Y., Acute toxicity formation potential of benzophenone-type UV filters in chlorination disinfection process. J. Environ. Sci. 26 (2014), 440–447.
23. [23] Tang, X., Wu, Q.-Y., Du, Y., Yang, Y., Hu, H.-Y., Anti-estrogenic activity formation potential assessment and precursor analysis in reclaimed water during chlorination. Water Res. 48 (2014), 490–497.
24. [24] Li, Y., Zhang, X., Shang, C., Effect of reductive property of activated carbon on total organic halogen analysis. Environ. Sci. Technol. 44 (2010), 2105–2111.
25. [25] Li, Y., Zhang, X., Shang, C., Krasner, S.W., Evaluation and improvement of total organic bromine analysis with respect to reductive property of activated carbon. Water Res. 45 (2011), 1229–1237.
26. [26] Pan, Y., Zhang, X., Total organic iodine measurement: a new approach with UPLC/ESI–MS for off-line iodide separation/detection. Water Res. 47 (2013), 163–172.
27. [27] Ates, N., Kaplan, S.S., Sahinkaya, E., Kitis, M., Dilek, F.B., Yetis, U., Occurrence of disinfection by-products in low DOC surface waters in Turkey. J. Hazard. Mater. 142 (2007), 526–534.
28. [28] Ates, N., Yetis, U., Kitis, M., Effects of bromide ion and natural organic matter fractions on the formation and speciation of chlorination by-products. J. Environ. Eng. 133 (2007), 947–954.
29. [29] Le Roux, J., Gallard, H., Croué, J.P., Chloramination of nitrogenous contaminants (pharmaceuticals and pesticides): NDMA and halogenated DBPs formation. Water Res. 45 (2011), 3164–3174.
30. [30] Zhai, H., Zhang, X., Zhu, X., Liu, J., Ji, M., Formation of brominated disinfection byproducts during chloramination of drinking water: new polar species and overall kinetics. Environ. Sci. Technol. 48 (2014), 2579–2588.
31. [31] Pan, Y., Zhang, X., Wagner, E.D., Osiol, J., Plewa, M.J., Boiling of simulated tap water: effect on polar brominated disinfection byproducts halogen speciation, and cytotoxicity. Environ. Sci. Technol. 48 (2013), 149–156.
32. [32] Broyer, L., Goetsch, L., Broussas, M., Evaluation of complement-Dependent cytotoxicity using ATP measurement and C1q/C4b binding. Glycosylation Eng. Biopharm.: Methods Protoc., 2013, 319–329.
33. [33] ISO 9562, Water Quality: Determination of Adsorbable Organically Bound Halogens. 2004.
34. [34] Pals, J., Attene-Ramos, M.S., Xia, M., Wagner, E.D., Plewa, M.J., Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts. Environ. Sci. Technol. 47 (2013), 12514–12523.
35. [35] Plewa, M.J., Wagner, E.D., Metz, D.H., Kashinkunti, R., Jamriska, K.J., Meyer, M., Differential toxicity of drinking water disinfected with combinations of ultraviolet radiation and chlorine. Environ. Sci. Technol. 46 (2012), 7811–7817.
36. [36] Domino, M.M., Pepich, B.V., Munch, D.J., Fair, P.S., Xie, Y., Munch, J.W., Determination of haloacetic acids and dalapon in drinking water by liquid–liquid microextraction, derivatization, and gas chromatography with electron capture detection. EPA Methods, 552, 2003.
37. [37] Deng, Z., Yang, X., Shang, C., Zhang, X., Electrospray ionization-tandem mass spectrometry method for differentiating chlorine substitution in disinfection byproduct formation. Environ. Sci. Technol. 48 (2014), 4877–4884.
38. [38] Zhai, H., Zhang, X., A new method for differentiating adducts of common drinking water DBPs from higher molecular weight DBPs in electrospray ionization-mass spectrometry analysis. Water Res. 43 (2009), 2093–2100.
39. [39] Wang, D., Bolton, J.R., Andrews, S.A., Hofmann, R., Comparison of hydrogen peroxide to ammonium ions and sulfite as a free chlorine quenching agent for disinfection by-Product measurement. J. Environ. Eng., 2016, 06016002.
40. [40] Wu, Q.-Y., Li, Y., Hu, H.-Y., Ding, Y.-N., Huang, H., Zhao, F.-Y., Removal of genotoxicity in chlorinated secondary effluent of a domestic wastewater treatment plant during quenching. Environ. Sci. Pollut. R. 19 (2012), 1–7.
41. [41] Liu, J., Zhang, X., Effect of quenching time and quenching agent dose on total organic halogen measurement. Int. J. Environ. Anal. Chem. 93 (2013), 1146–1158.
42. [42] Wang, L.-S., Hu, H.-Y., Wang, C., Effect of ammonia nitrogen and dissolved organic matter fractions on the genotoxicity of wastewater effluent during chlorine disinfection. Environ. Sci. Technol. 41 (2007), 160–165.
43. [43] Asano, T., Burton, F., Leverenz, H., Tsuchihashi, R., Tchobanoglous, G., Water Reuse. 2007, McGrawHill, New York, USA.
44. [44] Duong, H.A., Berg, M., Hoang, M.H., Pham, H.V., Gallard, H., Giger, W., von Gunten, U., Trihalomethane formation by chlorination of ammonium-and bromide-containing groundwater in water supplies of Hanoi. Vietnam Water Res. 37 (2003), 3242–3252.
45. [45] Yang, X., Shang, C., Huang, J.-C., DBP formation in breakpoint chlorination of wastewater. Water Res. 39 (2005), 4755–4767.
46. [46] Lu, J., Zhang, T., Ma, J., Chen, Z., Evaluation of disinfection by-products formation during chlorination and chloramination of dissolved natural organic matter fractions isolated from a filtered river water. J. Hazard. Mater. 162 (2009), 140–145.
47. [47] Yang, X., Shang, C., Westerhoff, P., Factors affecting formation of haloacetonitriles haloketones, chloropicrin and cyanogen halides during chloramination. Water Res. 41 (2007), 1193–1200.
48. [48] Koczwara, M.K., Kirsch, E.J., Grady, C.L., Formation of organic chlorine in activated sludge effluents. Water Res. 17 (1983), 1863–1869.
49. [49] Croue, J.P., Reckhow, D.A., Destruction of chlorination byproducts with sulfite. Environ. Sci. Technol. 23 (1989), 1412–1419.
50. [50] Rebhun, M., Heller-Grossman, L., Manka, J., Formation of disinfection byproducts during chlorination of secondary effluent and renovated water. Water Environ. Res. 69 (1997), 1154–1162.
51. [51] Savant, D.V., Abdul-Rahman, R., Ranade, D.R., Anaerobic degradation of adsorbable organic halides (AOX) from pulp and paper industry wastewater. Bioresour. Technol. 97 (2006), 1092–1104.
52. [52] Gong, T., Zhang, X., Determination of iodide: iodate and organo-iodine in waters with a new total organic iodine measurement approach. Water Res. 47 (2013), 6660–6669.
53. [53] De Vera, G.A., Stalter, D., Gernjak, W., Weinberg, H.S., Keller, J., Farré, M.J., Towards reducing DBP formation potential of drinking water by favouring direct ozone over hydroxyl radical reactions during ozonation. Water Res. 87 (2015), 49–58.
54. [54] Gao, N.-Y., Chu, W.-H., Deng, Y., Xu, B., TCAA degradation in ultraviolet (UV) irradiation/hydrogen peroxide (H2O2)/micro-aeration (MCA) combination process. J. Water Supply Res. Technol. 58 (2009), 510–518.
55. [55] Li, X.-C., Ma, J., Liu, G.-F., Fang, J.-Y., Yue, S.-Y., Guan, Y.-H., Chen, L.-W., Liu, X.-W., Efficient reductive quenching of monochloroacetic acid by sulfite/UV process. Environ. Sci. Technol. 46 (2012), 7342–7349.
56. [56] Chen, B., Westerhoff, P., Predicting disinfection by-product formation potential in water. Water Res. 44 (2010), 3755–3762.
57. [57] Hu, H.-Y., Du, Y., Wu, Q.-Y., Zhao, X., Tang, X., Chen, Z., Differences in dissolved organic matter between reclaimed water source and drinking water source. Sci. Total Environ. 551 (2016), 133–142.
58. [58] White, D.M., Garland, D.S., Narr, J., Woolard, C.R., Natural organic matter and DBP formation potential in Alaskan water supplies. Water Res. 37 (2003), 939–947.
59. [59] Sirivedhin, T., Gray, K.A., 2. Comparison of the disinfection by-product formation potentials between a wastewater effluent and surface waters. Water Res. 39 (2005), 1025–1036.
60. [60] Pifer, A.D., Fairey, J.L., Suitability of organic matter surrogates to predict trihalomethane formation in drinking water sources. Environ. Eng. Sci. 31 (2014), 117–126.
61. [61] Pifer, A.D., Cousins, S.L., Fairey, J.L., Assessing UV-and fluorescence-based metrics as disinfection byproduct precursor surrogate parameters in a water body influenced by a heavy rainfall event. J. Water Supply Res. Technol. 63 (2014), 200–211.