Toxicity testing in the 21st century: Implications for human health risk assessment: Perspective

Risk Analysis

Volumn 29, Issue 4, 2009, Pages 474-479

  Krewski, Daniel ^a   Andersen, Melvin E ^b   Mantus, Ellen ^c   Zeise, Lauren ^d  

^a UNIVERSITY OF OTTAWA   (Canada)

^b HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^c National Research Council   (United States)

^d CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSESSMENT PRACTICES; CELL LINES; CHEMICAL RISK ASSESSMENTS; COST-EFFECTIVE METHODS; ENVIRONMENTAL AGENTS; EXPERIMENTAL ANIMALS; FUNCTIONAL GENOMICS; HIGH CONTENTS; HUMAN CELLS; HUMAN HEALTH RISK ASSESSMENTS; HUMAN HEALTHS; IN-VITRO; IN-VITRO TESTS; NATIONAL RESEARCH COUNCILS; SCIENTIFIC ADVANCES; SCREENING ASSAYS; STRATEGIC PLANS; SYSTEMS BIOLOGIES; TESTING METHODOLOGIES; TOXIC CHEMICALS; TOXICITY TESTING; TRANSCRIPTOMICS;

ACOUSTIC NOISE; ANIMALS; CELL CULTURE; ENVIRONMENTAL PROTECTION AGENCY; HEALTH; HEALTH RISKS; RISK ASSESSMENT; RISK MANAGEMENT; STRATEGIC PLANNING; TISSUE CULTURE;

TOXICITY;

BIOLOGICAL MARKER; TOXIC SUBSTANCE;

BIOMARKER; ENVIRONMENTAL PROTECTION; GENOMICS; HEALTH RISK; PUBLIC HEALTH; RISK ASSESSMENT; TOXICITY TEST; TWENTY FIRST CENTURY;

ANIMAL TESTING REDUCTION; ANIMAL TESTING REPLACEMENT; COST EFFECTIVENESS ANALYSIS; ENVIRONMENTAL EXPOSURE; FUNCTIONAL GENOMICS; HEALTH HAZARD; HIGH THROUGHPUT SCREENING; HUMAN; POPULATION RESEARCH; REVIEW; RISK ASSESSMENT; SCREENING TEST; SYSTEMS BIOLOGY; TOXICITY TESTING; TRANSCRIPTOMICS;

ANIMALS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; HISTORY, 21ST CENTURY; HUMANS; RISK ASSESSMENT; TOXICITY TESTS;

ANIMALIA;

EID: 62749109092     PISSN: 02724332     EISSN: 15396924     Source Type: Journal    
DOI: 10.1111/j.1539-6924.2008.01150.x     Document Type: Review

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