PD-1/PD-L pathway inhibits M.tb-specific CD4+ T-cell functions and phagocytosis of macrophages in active tuberculosis

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Shen, Lei ^a,b   Gao, Yan ^b   Liu, Yuanyuan ^b   Zhang, Bingyan ^b   Liu, Qianqian ^b   Wu, Jing ^b   Fan, Lin ^a   Ou, Qinfang ^c   Zhang, Wenhong ^b,d   Shao, Lingyun ^b  

^a TONGJI UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c Wu Xi Infectious Diseases Hospital   (China)

^d FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD274 PROTEIN, HUMAN; GAMMA INTERFERON; LIPOPOLYSACCHARIDE RECEPTOR; NEUTRALIZING ANTIBODY; PDCD1 PROTEIN, HUMAN; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR;

ADULT; ANTAGONISTS AND INHIBITORS; CASE CONTROL STUDY; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CELLULAR IMMUNITY; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; LUNG TUBERCULOSIS; MACROPHAGE; MALE; MICROBIOLOGY; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; PRIMARY CELL CULTURE;

ADULT; ANTIBODIES, NEUTRALIZING; B7-H1 ANTIGEN; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, CELLULAR; IMMUNITY, INNATE; INTERFERON-GAMMA; LIPOPOLYSACCHARIDE RECEPTORS; MACROPHAGES; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; PRIMARY CELL CULTURE; PROGRAMMED CELL DEATH 1 RECEPTOR; TUBERCULOSIS, PULMONARY;

EID: 85002976520     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep38362     Document Type: Article

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