Elite controller CD8+ T cells exhibit comparable viral inhibition capacity, but better sustained effector properties compared to chronic progressors

Journal of Leukocyte Biology

Volumn 100, Issue 6, 2016, Pages 1425-1433

  Shasha, David ^a   Karel, Dan ^a   Angiuli, Olivia ^a   Greenblatt, Adam ^a   Ghebremichael, Musie ^a   Yu, Xu ^a   Porichis, Filippos ^a   Walker, Bruce D ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Apoptosis; HIV control; IL 15; Polyfunctionality

Indexed keywords

ANTIVIRUS AGENT; INTERLEUKIN 15; T LYMPHOCYTE RECEPTOR;

ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CELL LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCUBATION TIME; PRIORITY JOURNAL; VIRUS INHIBITION; VIRUS REPLICATION; CELL CULTURE; COMPARATIVE STUDY; CRYOPRESERVATION; CYTOTOXICITY; DISEASE COURSE; HIV INFECTIONS; IMMUNOLOGY; PHYSIOLOGY; T LYMPHOCYTE SUBPOPULATION;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; APOPTOSIS; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CRYOPRESERVATION; CYTOTOXICITY, IMMUNOLOGIC; DISEASE PROGRESSION; HIV; HIV INFECTIONS; HUMANS; INTERLEUKIN-15; T-CELL ANTIGEN RECEPTOR SPECIFICITY; T-LYMPHOCYTE SUBSETS; VIRUS REPLICATION;

EID: 85002868130     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.4A0915-422R     Document Type: Article

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