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Volumn 2, Issue 8, 2014, Pages

Acute and chronic systemic CB1 cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats

Author keywords

Baroreflex; Endocannabinoid system; Hypertension; Metabolic syndrome; Reninangiotensin system

Indexed keywords

ANGIOTENSIN; CANNABINOID 1 RECEPTOR; ENDOCANNABINOID; HORMONE; INSULIN; LEPTIN; RENIN; RIMONABANT;

EID: 85002595440     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.14814/phy2.12108     Document Type: Article
Times cited : (26)

References (60)
  • 2
    • 70449706328 scopus 로고    scopus 로고
    • Leptin impairs cardiovagal baroreflex function at the level of the solitary tract nucleus
    • Arnold, A. C., H. A. Shaltout, P. E. Gallagher, and D. I. Diz. 2009. Leptin impairs cardiovagal baroreflex function at the level of the solitary tract nucleus. Hypertension 54: 1001-1008.
    • (2009) Hypertension , vol.54 , pp. 1001-1008
    • Arnold, A.C.1    Shaltout, H.A.2    Gallagher, P.E.3    Diz, D.I.4
  • 3
    • 0026560448 scopus 로고
    • Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats
    • Bader, M., Y. Zhao, M. Sander, M. A. Lee, J. Bachmann, M. Bohm, et al. 1992. Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats. Hypertension 19: 681-686.
    • (1992) Hypertension , vol.19 , pp. 681-686
    • Bader, M.1    Zhao, Y.2    Sander, M.3    Lee, M.A.4    Bachmann, J.5    Bohm, M.6
  • 4
    • 20844454912 scopus 로고    scopus 로고
    • Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
    • Batkai, S., P. Pacher, D. Osei-Hyiaman, S. Radaeva, J. Liu, J. Harvey-White, et al. 2004. Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation 110: 1996-2002.
    • (2004) Circulation , vol.110 , pp. 1996-2002
    • Batkai, S.1    Pacher, P.2    Osei-Hyiaman, D.3    Radaeva, S.4    Liu, J.5    Harvey-White, J.6
  • 5
    • 84875247295 scopus 로고    scopus 로고
    • Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB(1) receptor blockade
    • Bellocchio, L., E. Soria-Gomez, C. Quarta, M. Metna-Laurent, P. Cardinal, E. Binder, et al. 2013. Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB(1) receptor blockade. Proc. Natl Acad. Sci. USA 110: 4786-4791.
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 4786-4791
    • Bellocchio, L.1    Soria-Gomez, E.2    Quarta, C.3    Metna-Laurent, M.4    Cardinal, P.5    Binder, E.6
  • 6
    • 57149147131 scopus 로고    scopus 로고
    • Metabolic effects of an AT1-receptor blockade combined with HCTZ in cardiac risk patients: A non interventional study in primary care
    • Bramlage, P., E. Schonrock, and P. Odoj. 2008. Metabolic effects of an AT1-receptor blockade combined with HCTZ in cardiac risk patients: a non interventional study in primary care. BMC Cardiovasc. Disord. 8: 30.
    • (2008) BMC Cardiovasc. Disord. , vol.8 , pp. 30
    • Bramlage, P.1    Schonrock, E.2    Odoj, P.3
  • 7
    • 0141962681 scopus 로고    scopus 로고
    • Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen2, Lewis rat
    • Chappell, M. C., P. E. Gallagher, D. B. Averill, C. M. Ferrario, and K. B. Brosnihan. 2003. Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen2, Lewis rat. Hypertension 42: 781-786.
    • (2003) Hypertension , vol.42 , pp. 781-786
    • Chappell, M.C.1    Gallagher, P.E.2    Averill, D.B.3    Ferrario, C.M.4    Brosnihan, K.B.5
  • 8
    • 84894042086 scopus 로고    scopus 로고
    • Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides
    • Cinar, R., G. Godlewski, J. Liu, J. Tam, T. Jourdan, B. Mukhopadhyay, et al. 2014. Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides. Hepatology 59: 143-153.
    • (2014) Hepatology , vol.59 , pp. 143-153
    • Cinar, R.1    Godlewski, G.2    Liu, J.3    Tam, J.4    Jourdan, T.5    Mukhopadhyay, B.6
  • 9
    • 85047690626 scopus 로고    scopus 로고
    • The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    • Cota, D., G. Marsicano, M. Tschop, Y. Grubler, C. Flachskamm, M. Schubert, et al. 2003. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J. Clin. Invest. 112: 423-431.
    • (2003) J. Clin. Invest. , vol.112 , pp. 423-431
    • Cota, D.1    Marsicano, G.2    Tschop, M.3    Grubler, Y.4    Flachskamm, C.5    Schubert, M.6
  • 10
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • Despres, J. P., A. Golay, and L. Sjostrom. 2005. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N. Engl. J. Med. 353: 2121-2134.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 2121-2134
    • Despres, J.P.1    Golay, A.2    Sjostrom, L.3
  • 11
    • 0035848818 scopus 로고    scopus 로고
    • Leptin-regulated endocannabinoids are involved in maintaining food intake
    • Di Marzo, V., S. K. Goparaju, L. Wang, J. Liu, S. Batkai, Z. Jarai, et al. 2001. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 410: 822-825.
    • (2001) Nature , vol.410 , pp. 822-825
    • Di Marzo, V.1    Goparaju, S.K.2    Wang, L.3    Liu, J.4    Batkai, S.5    Jarai, Z.6
  • 12
    • 0037356826 scopus 로고    scopus 로고
    • The role of the novel adipocyte-derived hormone adiponectin in human disease
    • Diez, J. J., and P. Iglesias. 2003. The role of the novel adipocyte-derived hormone adiponectin in human disease. Eur. J. Endocrinol. 148: 293-300.
    • (2003) Eur. J. Endocrinol. , vol.148 , pp. 293-300
    • Diez, J.J.1    Iglesias, P.2
  • 13
    • 62449095179 scopus 로고    scopus 로고
    • Spontaneous baroreflex measures are unable to detect age-related impairments in cardiac baroreflex function during dynamic exercise in humans
    • Fisher, J. P., S. Ogoh, C. Junor, A. Khaja, M. Northrup, and P. J. Fadel. 2009. Spontaneous baroreflex measures are unable to detect age-related impairments in cardiac baroreflex function during dynamic exercise in humans. Exp. Physiol. 94: 447-458.
    • (2009) Exp. Physiol. , vol.94 , pp. 447-458
    • Fisher, J.P.1    Ogoh, S.2    Junor, C.3    Khaja, A.4    Northrup, M.5    Fadel, P.J.6
  • 14
    • 84893651437 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2014 update: A report from the american heart association
    • Go, A. S., D. Mozaffarian, V. L. Roger, E. J. Benjamin, J. D. Berry, M. J. Blaha, et al. 2014. Heart disease and stroke statistics-2014 update: a report from the american heart association. Circulation 129: e28-e292.
    • (2014) Circulation , vol.129 , pp. e28-e292
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3    Benjamin, E.J.4    Berry, J.D.5    Blaha, M.J.6
  • 15
    • 0025122173 scopus 로고
    • Blood pressure and sympathetic activity in spontaneously hypertensive rats during food restriction
    • Gradin, K., and B. Persson. 1990. Blood pressure and sympathetic activity in spontaneously hypertensive rats during food restriction. J. Neural Transm. Gen. Sect. 79: 183-191.
    • (1990) J. Neural Transm. Gen. Sect. , vol.79 , pp. 183-191
    • Gradin, K.1    Persson, B.2
  • 17
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • Grundy, S. M., J. I. Cleeman, S. R. Daniels, K. A. Donato, R. H. Eckel, B. A. Franklin, et al. 2005. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112: 2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3    Donato, K.A.4    Eckel, R.H.5    Franklin, B.A.6
  • 18
    • 84857794906 scopus 로고    scopus 로고
    • Regulation of endocannabinoid release by G proteins: A paracrine mechanism of G protein-coupled receptor action
    • Gyombolai, P., D. Pap, G. Turu, K. J. Catt, G. Bagdy, and L. Hunyady. 2012. Regulation of endocannabinoid release by G proteins: a paracrine mechanism of G protein-coupled receptor action. Mol. Cell. Endocrinol. 353: 29-36.
    • (2012) Mol. Cell. Endocrinol. , vol.353 , pp. 29-36
    • Gyombolai, P.1    Pap, D.2    Turu, G.3    Catt, K.J.4    Bagdy, G.5    Hunyady, L.6
  • 19
    • 84877334814 scopus 로고    scopus 로고
    • Renin-angiotensin system: Upgrade of recent knowledge and perspectives
    • Herichova, I., and K. Szantoova. 2013. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr. Regul. 47: 39-52.
    • (2013) Endocr. Regul. , vol.47 , pp. 39-52
    • Herichova, I.1    Szantoova, K.2
  • 20
    • 65549099178 scopus 로고    scopus 로고
    • Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats
    • Ho, W. S., and S. M. Gardiner. 2009. Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. Br. J. Pharmacol. 156: 94-104.
    • (2009) Br. J. Pharmacol. , vol.156 , pp. 94-104
    • Ho, W.S.1    Gardiner, S.M.2
  • 22
    • 33645785648 scopus 로고    scopus 로고
    • Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems
    • Kasper, S. O., C. S. Carter, C. M. Ferrario, D. Ganten, L. F. Ferder, W. E. Sonntag, et al. 2005. Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems. Physiol. Genomics 23: 311-317.
    • (2005) Physiol. Genomics , vol.23 , pp. 311-317
    • Kasper, S.O.1    Carter, C.S.2    Ferrario, C.M.3    Ganten, D.4    Ferder, L.F.5    Sonntag, W.E.6
  • 23
    • 84858984433 scopus 로고    scopus 로고
    • 1 receptor antagonists: New discoveries leading to new perspectives
    • 1 receptor antagonists: new discoveries leading to new perspectives. Acta Physiol. (Oxf) 205: 41-60.
    • (2012) Acta Physiol. (Oxf) , vol.205 , pp. 41-60
    • Kirilly, E.1    Gonda, X.2    Bagdy, G.3
  • 24
    • 0030991629 scopus 로고    scopus 로고
    • Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats
    • Lake, K. D., B. R. Martin, G. Kunos, and K. Varga. 1997. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. Hypertension 29: 1204-1210.
    • (1997) Hypertension , vol.29 , pp. 1204-1210
    • Lake, K.D.1    Martin, B.R.2    Kunos, G.3    Varga, K.4
  • 25
    • 0029067246 scopus 로고
    • Beta-blockers and their effects on protein metabolism and resting energy expenditure
    • Lamont, L. S. 1995. Beta-blockers and their effects on protein metabolism and resting energy expenditure. J. Cardiopulm. Rehabil. 15: 183-185.
    • (1995) J. Cardiopulm. Rehabil. , vol.15 , pp. 183-185
    • Lamont, L.S.1
  • 26
    • 84863419730 scopus 로고    scopus 로고
    • Effects of chronic antagonism of endocannabinoid-1 receptors on glucose tolerance and insulin action in skeletal muscles of lean and obese Zucker rats
    • Lindborg, K. A., S. Jacob, and E. J. Henriksen. 2011. Effects of chronic antagonism of endocannabinoid-1 receptors on glucose tolerance and insulin action in skeletal muscles of lean and obese Zucker rats. Cardiorenal Med. 1: 31-44.
    • (2011) Cardiorenal Med. , vol.1 , pp. 31-44
    • Lindborg, K.A.1    Jacob, S.2    Henriksen, E.J.3
  • 27
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei, M., J. Halaas, E. Ravussin, R. E. Pratley, G. H. Lee, Y. Zhang, et al. 1995. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1: 1155-1161.
    • (1995) Nat. Med. , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3    Pratley, R.E.4    Lee, G.H.5    Zhang, Y.6
  • 28
    • 0030572871 scopus 로고    scopus 로고
    • Insulin microinjection into the nucleus tractus solitarii of the rat attenuates the baroreceptor reflex
    • McKernan, A. M., and F. R. Calaresu. 1996. Insulin microinjection into the nucleus tractus solitarii of the rat attenuates the baroreceptor reflex. J. Auton. Nerv. Syst. 61: 128-138.
    • (1996) J. Auton. Nerv. Syst. , vol.61 , pp. 128-138
    • McKernan, A.M.1    Calaresu, F.R.2
  • 30
    • 84892415944 scopus 로고    scopus 로고
    • Chronic blockade of angiotensin AT1 receptors improves cardinal symptoms of metabolic syndrome in diet-induced obesity in rats
    • Muller-Fielitz, H., N. Hubel, M. Mildner, F. M. Vogt, J. Barkhausen, and W. Raasch. 2014. Chronic blockade of angiotensin AT1 receptors improves cardinal symptoms of metabolic syndrome in diet-induced obesity in rats. Br. J. Pharmacol. 171: 746-760.
    • (2014) Br. J. Pharmacol. , vol.171 , pp. 746-760
    • Muller-Fielitz, H.1    Hubel, N.2    Mildner, M.3    Vogt, F.M.4    Barkhausen, J.5    Raasch, W.6
  • 32
    • 0033108027 scopus 로고    scopus 로고
    • Lipid disorders in obesity
    • Nicholas, S. B. 1999. Lipid disorders in obesity. Curr. Hypertens. Rep. 1: 131-136.
    • (1999) Curr. Hypertens. Rep. , vol.1 , pp. 131-136
    • Nicholas, S.B.1
  • 33
    • 0030872917 scopus 로고    scopus 로고
    • Hypercholesterolemia is associated with enhanced angiotensin AT1-receptor expression
    • Nickenig, G., O. Jung, K. Strehlow, O. Zolk, W. Linz, B. A. Scholkens, et al. 1997. Hypercholesterolemia is associated with enhanced angiotensin AT1-receptor expression. Am. J. Physiol. 272: H2701-H2707.
    • (1997) Am. J. Physiol. , vol.272 , pp. H2701-H2707
    • Nickenig, G.1    Jung, O.2    Strehlow, K.3    Zolk, O.4    Linz, W.5    Scholkens, B.A.6
  • 34
    • 78149487137 scopus 로고    scopus 로고
    • Adenoviral inhibition of AT1a receptors in the paraventricular nucleus inhibits acute increases in mean arterial blood pressure in the rat
    • Northcott, C. A., S. Watts, Y. Chen, M. Morris, A. Chen, and J. R. Haywood. 2010. Adenoviral inhibition of AT1a receptors in the paraventricular nucleus inhibits acute increases in mean arterial blood pressure in the rat. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299: R1202-R1211.
    • (2010) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.299 , pp. R1202-R1211
    • Northcott, C.A.1    Watts, S.2    Chen, Y.3    Morris, M.4    Chen, A.5    Haywood, J.R.6
  • 36
    • 35649006862 scopus 로고    scopus 로고
    • Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed
    • Pakdeechote, P., W. R. Dunn, and V. Ralevic. 2007. Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed. Br. J. Pharmacol. 152: 725-733.
    • (2007) Br. J. Pharmacol. , vol.152 , pp. 725-733
    • Pakdeechote, P.1    Dunn, W.R.2    Ralevic, V.3
  • 37
    • 57649194932 scopus 로고    scopus 로고
    • Peripherally administered angiotensin II AT1 receptor antagonists are anti-stress compounds in vivo
    • Pavel, J., J. Benicky, Y. Murakami, E. Sanchez-Lemus, and J. M. Saavedra. 2008. Peripherally administered angiotensin II AT1 receptor antagonists are anti-stress compounds in vivo. Ann. N. Y. Acad. Sci. 1148: 360-366.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1148 , pp. 360-366
    • Pavel, J.1    Benicky, J.2    Murakami, Y.3    Sanchez-Lemus, E.4    Saavedra, J.M.5
  • 38
    • 78650120798 scopus 로고    scopus 로고
    • International union of basic and clinical pharmacology. LXXIX. Cannabinoid receptors and their ligands: Beyond CB(1) and CB(2)
    • Pertwee, R. G., A. C. Howlett, M. E. Abood, S. P. Alexander, V. Di Marzo, M. R. Elphick, et al. 2010. International union of basic and clinical pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB(1) and CB(2). Pharmacol. Rev. 62: 588-631.
    • (2010) Pharmacol. Rev. , vol.62 , pp. 588-631
    • Pertwee, R.G.1    Howlett, A.C.2    Abood, M.E.3    Alexander, S.P.4    Di Marzo, V.5    Elphick, M.R.6
  • 39
    • 33744986319 scopus 로고    scopus 로고
    • Cannabinoid receptor signaling directly inhibits thermogenesis and alters expression of adiponectin and visfatin
    • Perwitz, N., M. Fasshauer, and J. Klein. 2006. Cannabinoid receptor signaling directly inhibits thermogenesis and alters expression of adiponectin and visfatin. Horm. Metab. Res. 38: 356-358.
    • (2006) Horm. Metab. Res. , vol.38 , pp. 356-358
    • Perwitz, N.1    Fasshauer, M.2    Klein, J.3
  • 42
    • 79958865842 scopus 로고    scopus 로고
    • AT1R-CB(1)R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II
    • Rozenfeld, R., A. Gupta, K. Gagnidze, M. P. Lim, I. Gomes, D. Lee-Ramos, et al. 2011. AT1R-CB(1)R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II. EMBO J. 30: 2350-2363.
    • (2011) EMBO J. , vol.30 , pp. 2350-2363
    • Rozenfeld, R.1    Gupta, A.2    Gagnidze, K.3    Lim, M.P.4    Gomes, I.5    Lee-Ramos, D.6
  • 43
    • 38149109182 scopus 로고    scopus 로고
    • Effect of rimonabant on blood pressure in overweight/obese patients with/without co-morbidities: Analysis of pooled RIO study results
    • Ruilope, L. M., J. P. Despres, A. Scheen, X. Pi-Sunyer, G. Mancia, A. Zanchetti, et al. 2008. Effect of rimonabant on blood pressure in overweight/obese patients with/without co-morbidities: analysis of pooled RIO study results. J. Hypertens. 26: 357-367.
    • (2008) J. Hypertens. , vol.26 , pp. 357-367
    • Ruilope, L.M.1    Despres, J.P.2    Scheen, A.3    Pi-Sunyer, X.4    Mancia, G.5    Zanchetti, A.6
  • 44
    • 85002921703 scopus 로고    scopus 로고
    • 1 cannabinoid receptor tone contributes to impaired baroreflex sensitivity in hypertensive (mRen2)27 transgenic rats
    • 926.913 (Abstract)
    • 1 cannabinoid receptor tone contributes to impaired baroreflex sensitivity in hypertensive (mRen2)27 transgenic rats. FASEB J. 27: 926.913 (Abstract).
    • (2013) FASEB J. , vol.27
    • Schaich, C.L.1    Howlett, A.C.2    Chappell, M.C.3    Nautiyal, M.4    Diz, D.I.5
  • 45
    • 23944472974 scopus 로고    scopus 로고
    • Mechanism of fatty acids induced suppression of cardiovascular reflexes in rats
    • Shaltout, H. A., and A. A. Abdel-Rahman. 2005. Mechanism of fatty acids induced suppression of cardiovascular reflexes in rats. J. Pharmacol. Exp. Ther. 314: 1328-1337.
    • (2005) J. Pharmacol. Exp. Ther. , vol.314 , pp. 1328-1337
    • Shaltout, H.A.1    Abdel-Rahman, A.A.2
  • 46
    • 80054855020 scopus 로고    scopus 로고
    • Peripheral effects of the endocannabinoid system in energy homeostasis: Adipose tissue, liver and skeletal muscle
    • Silvestri, C., A. Ligresti, and V. Di Marzo. 2011. Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle. Rev. Endocr. Metab. Disord. 12: 153-162.
    • (2011) Rev. Endocr. Metab. Disord. , vol.12 , pp. 153-162
    • Silvestri, C.1    Ligresti, A.2    Di Marzo, V.3
  • 47
    • 84879837213 scopus 로고    scopus 로고
    • Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome
    • Slavic, S., D. Lauer, M. Sommerfeld, U. R. Kemnitz, A. Grzesiak, M. Trappiel, et al. 2013. Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome. J. Mol. Med. (Berl) 91: 811-823.
    • (2013) J. Mol. Med. (Berl) , vol.91 , pp. 811-823
    • Slavic, S.1    Lauer, D.2    Sommerfeld, M.3    Kemnitz, U.R.4    Grzesiak, A.5    Trappiel, M.6
  • 49
    • 28444471259 scopus 로고    scopus 로고
    • Selective angiotensin II receptor antagonism enhances whole-body insulin sensitivity and muscle glucose transport in hypertensive TG(mREN2)27 rats
    • Sloniger, J. A., V. Saengsirisuwan, C. J. Diehl, J. S. Kim, and E. J. Henriksen. 2005b. Selective angiotensin II receptor antagonism enhances whole-body insulin sensitivity and muscle glucose transport in hypertensive TG(mREN2)27 rats. Metabolism 54: 1659-1668.
    • (2005) Metabolism , vol.54 , pp. 1659-1668
    • Sloniger, J.A.1    Saengsirisuwan, V.2    Diehl, C.J.3    Kim, J.S.4    Henriksen, E.J.5
  • 51
    • 84894031718 scopus 로고    scopus 로고
    • Role of adiponectin in the metabolic effects of cannabinoid receptor-1 blockade in mice with diet-induced obesity
    • Tam, J., G. Godlewski, B. J. Earley, L. Zhou, T. Jourdan, G. Szanda, et al. 2014. Role of adiponectin in the metabolic effects of cannabinoid receptor-1 blockade in mice with diet-induced obesity. Am. J. Physiol. Endocrinol. Metab. 306: E457-E468.
    • (2014) Am. J. Physiol. Endocrinol. Metab. , vol.306 , pp. E457-E468
    • Tam, J.1    Godlewski, G.2    Earley, B.J.3    Zhou, L.4    Jourdan, T.5    Szanda, G.6
  • 53
    • 77953099666 scopus 로고    scopus 로고
    • 1 receptor inhibition leads to decreased vascular AT1 receptor expression, inhibition of oxidative stress and improved endothelial function
    • 1 receptor inhibition leads to decreased vascular AT1 receptor expression, inhibition of oxidative stress and improved endothelial function. Basic Res. Cardiol. 105: 465-477.
    • (2010) Basic Res. Cardiol. , vol.105 , pp. 465-477
    • Tiyerili, V.1    Zimmer, S.2    Jung, S.3    Wassmann, K.4    Naehle, C.P.5    Lutjohann, D.6
  • 54
    • 41549156590 scopus 로고    scopus 로고
    • ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats
    • Toblli, J. E., M. C. Munoz, G. Cao, J. Mella, L. Pereyra, and R. Mastai. 2008. ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats. Obesity (Silver Spring) 16: 770-776.
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 770-776
    • Toblli, J.E.1    Munoz, M.C.2    Cao, G.3    Mella, J.4    Pereyra, L.5    Mastai, R.6
  • 56
    • 0023181872 scopus 로고
    • Responses of the hypothalamic-pituitary-adrenal and renin-angiotensin axes and the sympathetic system during controlled surgical and anesthetic stress
    • Udelsman, R., J. A. Norton, S. E. Jelenich, D. S. Goldstein, W. M. Linehan, D. L. Loriaux, et al. 1987. Responses of the hypothalamic-pituitary-adrenal and renin-angiotensin axes and the sympathetic system during controlled surgical and anesthetic stress. J. Clin. Endocrinol. Metab. 64: 986-994.
    • (1987) J. Clin. Endocrinol. Metab. , vol.64 , pp. 986-994
    • Udelsman, R.1    Norton, J.A.2    Jelenich, S.E.3    Goldstein, D.S.4    Linehan, W.M.5    Loriaux, D.L.6
  • 57
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • Van Gaal, L. F., A. M. Rissanen, A. J. Scheen, O. Ziegler, and S. Rossner. 2005. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365: 1389-1397.
    • (2005) Lancet , vol.365 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 59
    • 0032924113 scopus 로고    scopus 로고
    • Mesenteric vasodilation mediated by endothelial anandamide receptors
    • Wagner, J. A., K. Varga, Z. Jarai, and G. Kunos. 1999. Mesenteric vasodilation mediated by endothelial anandamide receptors. Hypertension 33: 429-434.
    • (1999) Hypertension , vol.33 , pp. 429-434
    • Wagner, J.A.1    Varga, K.2    Jarai, Z.3    Kunos, G.4
  • 60
    • 84873183866 scopus 로고    scopus 로고
    • Treatment of arterial hypertension in obese patients
    • Wenzel, U. O., R. Benndorf, and S. Lange. 2013. Treatment of arterial hypertension in obese patients. Semin. Nephrol. 33: 66-74.
    • (2013) Semin. Nephrol. , vol.33 , pp. 66-74
    • Wenzel, U.O.1    Benndorf, R.2    Lange, S.3


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