메뉴 건너뛰기




Volumn 30, Issue 12, 2016, Pages 4021-4032

Novel ketone diet enhances physical and cognitive performance

(20)  Murray, Andrew J a,c   Knight, Nicholas S a   Cole, Mark A b,f   Cochlin, Lowri E a   Carter, Emma a   Tchabanenko, Kirill b,g   Pichulik, Tica a   Gulston, Melanie K c,d   Atherton, Helen J a   Schroeder, Marie A a   Deacon, Robert M J a   Kashiwaya, Yoshihiro e   King, M Todd e   Pawlosky, Robert e   Rawlins, J Nicholas P a   Tyler, Damian J a   Griffin, Julian L c   Robertson, Jeremy b   Veech, Richard L e   Clarke, Kieran a  


Author keywords

Energetics; Exercise; Heart; Metabolism; Muscle

Indexed keywords

1,3 BUTANEDIOL; 3 HYDROXYBUTYL 3 HYDROXYBUTYRATE; 3 HYDROXYBUTYRIC ACID; ACETONE; ADENOSINE TRIPHOSPHATE; CHOLESTEROL; FATTY ACID; KETONE; LACTATE DEHYDROGENASE; PALM OIL; STARCH; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; CARBOHYDRATE DIET; FAT INTAKE; INSULIN;

EID: 85002322997     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201600773R     Document Type: Article
Times cited : (133)

References (67)
  • 1
    • 0000079144 scopus 로고
    • The role of citric acid in intermediate metabolism in animal tissue
    • Krebs, H., and Johnson, W. (1937) The role of citric acid in intermediate metabolism in animal tissue. Enzymologia 4, 148-156
    • (1937) Enzymologia , vol.4 , pp. 148-156
    • Krebs, H.1    Johnson, W.2
  • 2
    • 0014202070 scopus 로고
    • Chemiosmotic hypothesis of oxidative phosphorylation
    • Mitchell, P., and Moyle, J. (1967) Chemiosmotic hypothesis of oxidative phosphorylation. Nature 213, 137-139
    • (1967) Nature , vol.213 , pp. 137-139
    • Mitchell, P.1    Moyle, J.2
  • 3
    • 84904384275 scopus 로고    scopus 로고
    • Ketone ester effects on metabolism and transcription
    • Veech, R. L. (2014) Ketone ester effects on metabolism and transcription. J. Lipid Res. 55, 2004-2006
    • (2014) J. Lipid Res. , vol.55 , pp. 2004-2006
    • Veech, R.L.1
  • 4
    • 38349175327 scopus 로고    scopus 로고
    • Carbohydrateresponse element-binding protein deletion alters substrate utilization producing an energy-deficient liver
    • Burgess, S. C., Iizuka, K., Jeoung, N. H., Harris, R. A., Kashiwaya, Y., Veech, R. L., Kitazume, T., and Uyeda, K. (2008) Carbohydrateresponse element-binding protein deletion alters substrate utilization producing an energy-deficient liver. J. Biol. Chem. 283, 1670-1678
    • (2008) J. Biol. Chem. , vol.283 , pp. 1670-1678
    • Burgess, S.C.1    Iizuka, K.2    Jeoung, N.H.3    Harris, R.A.4    Kashiwaya, Y.5    Veech, R.L.6    Kitazume, T.7    Uyeda, K.8
  • 6
    • 85006219580 scopus 로고    scopus 로고
    • Acutenutritional ketosis: Implications for exercise performance and metabolism
    • Cox, P. J., and Clarke, K. (2014) Acutenutritional ketosis: implications for exercise performance and metabolism. Extrem. Physiol. Med. 3, 17
    • (2014) Extrem. Physiol. Med. , vol.3 , pp. 17
    • Cox, P.J.1    Clarke, K.2
  • 7
    • 0014954713 scopus 로고
    • Starvation inman
    • Cahill, G. F., Jr. (1970) Starvation inman. N. Engl. J. Med. 282, 668-675
    • (1970) N. Engl. J. Med. , vol.282 , pp. 668-675
    • Cahill, G.F.1
  • 8
    • 0003785728 scopus 로고
    • Alternate fuel utilization in brain
    • (Passonneau, J., Hawkins, R., Lust, W., and Welsh, F., eds.) William & Wilkins, Baltimore
    • Cahill, G., and Aoki, T. (1980) Alternate fuel utilization in brain. In Cerebral Metabolism and Neural Function (Passonneau, J., Hawkins, R., Lust, W., and Welsh, F., eds.), pp. 234-242, William & Wilkins, Baltimore
    • (1980) Cerebral Metabolism and Neural Function , pp. 234-242
    • Cahill, G.1    Aoki, T.2
  • 10
    • 13844312647 scopus 로고    scopus 로고
    • Treatment of Parkinson disease with dietinduced hyperketonemia: A feasibility study
    • Vanitallie, T. B., Nonas, C., Di Rocco, A., Boyar, K., Hyams, K., and Heymsfield, S. B. (2005) Treatment of Parkinson disease with dietinduced hyperketonemia: a feasibility study. Neurology 64, 728-730
    • (2005) Neurology , vol.64 , pp. 728-730
    • Vanitallie, T.B.1    Nonas, C.2    Di Rocco, A.3    Boyar, K.4    Hyams, K.5    Heymsfield, S.B.6
  • 11
    • 0042195889 scopus 로고    scopus 로고
    • Effect of a high-fat ketogenic diet on plasma levels of lipids, lipoproteins, and apolipoproteins in children
    • Kwiterovich, P. O., Jr., Vining, E. P. G., Pyzik, P., Skolasky, R., Jr., and Freeman, J. M. (2003) Effect of a high-fat ketogenic diet on plasma levels of lipids, lipoproteins, and apolipoproteins in children. JAMA 290, 912-920
    • (2003) JAMA , vol.290 , pp. 912-920
    • Kwiterovich, P.O.1    Vining, E.P.G.2    Pyzik, P.3    Skolasky, R.4    Freeman, J.M.5
  • 12
    • 0020525056 scopus 로고
    • The human metabolic response to chronic ketosis without caloric restriction: Physical and biochemical adaptation
    • Phinney, S. D., Bistrian, B. R., Wolfe, R. R., and Blackburn, G. L. (1983) The human metabolic response to chronic ketosis without caloric restriction: physical and biochemical adaptation. Metabolism 32, 757-768
    • (1983) Metabolism , vol.32 , pp. 757-768
    • Phinney, S.D.1    Bistrian, B.R.2    Wolfe, R.R.3    Blackburn, G.L.4
  • 15
    • 72749106820 scopus 로고    scopus 로고
    • Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding
    • Murray, A. J., Knight, N. S., Cochlin, L. E., McAleese, S., Deacon, R.M., Rawlins, J. N., and Clarke, K. (2009) Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding. FASEB J. 23, 4353-4360
    • (2009) FASEB J. , vol.23 , pp. 4353-4360
    • Murray, A.J.1    Knight, N.S.2    Cochlin, L.E.3    McAleese, S.4    Deacon, R.M.5    Rawlins, J.N.6    Clarke, K.7
  • 18
    • 0016248088 scopus 로고
    • Brain metabolite concentrations and redox states in rats fed diets containing 1,3-butanediol and ethanol
    • Veech, R. L., Harris, R. L., and Mehlman, M. A. (1974) Brain metabolite concentrations and redox states in rats fed diets containing 1,3-butanediol and ethanol. Toxicol. Appl. Pharmacol. 29, 196-203
    • (1974) Toxicol. Appl. Pharmacol. , vol.29 , pp. 196-203
    • Veech, R.L.1    Harris, R.L.2    Mehlman, M.A.3
  • 21
    • 50149105620 scopus 로고    scopus 로고
    • In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance
    • Schroeder, M. A., Cochlin, L. E., Heather, L. C., Clarke, K., Radda, G. K., and Tyler, D. J. (2008) In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance. Proc. Natl. Acad. Sci. USA 105, 12051-12056
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 12051-12056
    • Schroeder, M.A.1    Cochlin, L.E.2    Heather, L.C.3    Clarke, K.4    Radda, G.K.5    Tyler, D.J.6
  • 22
    • 0035033455 scopus 로고    scopus 로고
    • Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals
    • Naressi, A., Couturier, C., Castang, I., de Beer, R., and Graveron-Demilly, D. (2001) Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals. Comput. Biol. Med. 31, 269-286
    • (2001) Comput. Biol. Med. , vol.31 , pp. 269-286
    • Naressi, A.1    Couturier, C.2    Castang, I.3    De Beer, R.4    Graveron-Demilly, D.5
  • 23
    • 33744913519 scopus 로고    scopus 로고
    • Insulin resistance, abnormal energymetabolismand increased ischemic damage inthechronically infarcted rat heart
    • Murray, A. J., Lygate, C. A., Cole, M. A., Carr, C. A., Radda, G. K., Neubauer, S., and Clarke, K. (2006) Insulin resistance, abnormal energymetabolismand increased ischemic damage inthechronically infarcted rat heart. Cardiovasc. Res. 71, 149-157
    • (2006) Cardiovasc. Res. , vol.71 , pp. 149-157
    • Murray, A.J.1    Lygate, C.A.2    Cole, M.A.3    Carr, C.A.4    Radda, G.K.5    Neubauer, S.6    Clarke, K.7
  • 24
    • 84897960311 scopus 로고    scopus 로고
    • Effect of isoproterenol on myocardial perfusion, function, energy metabolism and nitric oxide pathway in the rat heart - A longitudinal MR study
    • Desrois, M., Kober, F., Lan, C., Dalmasso, C., Cole, M., Clarke, K., Cozzone, P. J., and Bernard, M. (2014) Effect of isoproterenol on myocardial perfusion, function, energy metabolism and nitric oxide pathway in the rat heart - a longitudinal MR study. NMR Biomed. 27, 529-538
    • (2014) NMR Biomed. , vol.27 , pp. 529-538
    • Desrois, M.1    Kober, F.2    Lan, C.3    Dalmasso, C.4    Cole, M.5    Clarke, K.6    Cozzone, P.J.7    Bernard, M.8
  • 25
    • 85002389436 scopus 로고    scopus 로고
    • Cardiac MRS studies in rodents and other animals
    • Dodd, M. S., Tyler, D. J., and Clarke, K. (2015) Cardiac MRS studies in rodents and other animals. eMagRes. 4, 811-820
    • (2015) EMagRes , vol.4 , pp. 811-820
    • Dodd, M.S.1    Tyler, D.J.2    Clarke, K.3
  • 26
    • 42749085693 scopus 로고    scopus 로고
    • Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart
    • Murray, A. J., Cole, M.A., Lygate, C.A., Carr, C.A., Stuckey, D. J., Little, S. E., Neubauer, S., and Clarke, K. (2008) Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart. J. Mol. Cell. Cardiol. 44, 694-700
    • (2008) J. Mol. Cell. Cardiol. , vol.44 , pp. 694-700
    • Murray, A.J.1    Cole, M.A.2    Lygate, C.A.3    Carr, C.A.4    Stuckey, D.J.5    Little, S.E.6    Neubauer, S.7    Clarke, K.8
  • 27
    • 33644666564 scopus 로고    scopus 로고
    • Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncouplingprotein levels
    • Murray, A. J., Panagia, M., Hauton, D., Gibbons, G. F., and Clarke, K. (2005) Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncouplingprotein levels. Diabetes 54, 3496-3502
    • (2005) Diabetes , vol.54 , pp. 3496-3502
    • Murray, A.J.1    Panagia, M.2    Hauton, D.3    Gibbons, G.F.4    Clarke, K.5
  • 28
    • 2342618822 scopus 로고    scopus 로고
    • Rapid determination of acetone in human plasma by gas chromatographymass spectrometry and solid-phase microextraction with on-fiber derivatization
    • Deng, C., Zhang, W., Zhang, J., and Zhang, X. (2004) Rapid determination of acetone in human plasma by gas chromatographymass spectrometry and solid-phase microextraction with on-fiber derivatization. J. Chromatogr.B Analyt. Technol. Biomed. LifeSci. 805, 235-240
    • (2004) J. Chromatogr.B Analyt. Technol. Biomed. LifeSci. , vol.805 , pp. 235-240
    • Deng, C.1    Zhang, W.2    Zhang, J.3    Zhang, X.4
  • 31
    • 0343701230 scopus 로고
    • Remembrance of places passed, spatial memory in rats
    • Olton, D., and Samuelson, R. (1976) Remembrance of places passed, spatial memory in rats. J. Exp. Psychol. 2, 97-116
    • (1976) J. Exp. Psychol. , vol.2 , pp. 97-116
    • Olton, D.1    Samuelson, R.2
  • 34
    • 0031259554 scopus 로고    scopus 로고
    • The effects of hypertrophy and diabetes on cardiac pyruvate dehydrogenase activity
    • Seymour, A.M., and Chatham, J.C. (1997) The effects of hypertrophy and diabetes on cardiac pyruvate dehydrogenase activity. J. Mol. Cell. Cardiol. 29, 2771-2778
    • (1997) J. Mol. Cell. Cardiol. , vol.29 , pp. 2771-2778
    • Seymour, A.M.1    Chatham, J.C.2
  • 36
  • 37
    • 84942878290 scopus 로고    scopus 로고
    • The ketogenic diet and sport: A possible marriage?
    • Paoli, A., Bianco, A., and Grimaldi, K. A. (2015) The ketogenic diet and sport: a possible marriage? Exerc. Sport Sci. Rev. 43, 153-162
    • (2015) Exerc. Sport Sci. Rev. , vol.43 , pp. 153-162
    • Paoli, A.1    Bianco, A.2    Grimaldi, K.A.3
  • 38
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten, S., Desvergne, B., and Wahli, W. (2000) Roles of PPARs in health and disease. Nature 405, 421-424
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 39
    • 77956201747 scopus 로고    scopus 로고
    • Aketone esterdiet increasesbrainmalonyl-CoA and uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat
    • Kashiwaya, Y., Pawlosky, R., Markis, W., King, M. T., Bergman, C., Srivastava, S., Murray, A., Clarke, K., and Veech, R. L. (2010) Aketone esterdiet increasesbrainmalonyl-CoA and uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat. J. Biol. Chem. 285, 25950-25956
    • (2010) J. Biol. Chem. , vol.285 , pp. 25950-25956
    • Kashiwaya, Y.1    Pawlosky, R.2    Markis, W.3    King, M.T.4    Bergman, C.5    Srivastava, S.6    Murray, A.7    Clarke, K.8    Veech, R.L.9
  • 40
    • 84948172262 scopus 로고    scopus 로고
    • An ester of β-hydroxybutyrate regulates cholesterol biosynthesis in rats and a cholesterol biomarker in humans
    • Kemper, M. F., Srivastava, S., Todd King, M., Clarke, K., Veech, R. L., and Pawlosky, R. J. (2015) An ester of β-hydroxybutyrate regulates cholesterol biosynthesis in rats and a cholesterol biomarker in humans. Lipids 50, 1185-1193
    • (2015) Lipids , vol.50 , pp. 1185-1193
    • Kemper, M.F.1    Srivastava, S.2    Todd King, M.3    Clarke, K.4    Veech, R.L.5    Pawlosky, R.J.6
  • 41
    • 84861764348 scopus 로고    scopus 로고
    • Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet
    • Srivastava, S., Kashiwaya, Y., King, M. T., Baxa, U., Tam, J., Niu, G., Chen, X., Clarke, K., and Veech, R. L. (2012) Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet. FASEB J. 26, 2351-2362
    • (2012) FASEB J. , vol.26 , pp. 2351-2362
    • Srivastava, S.1    Kashiwaya, Y.2    King, M.T.3    Baxa, U.4    Tam, J.5    Niu, G.6    Chen, X.7    Clarke, K.8    Veech, R.L.9
  • 42
    • 79960884485 scopus 로고    scopus 로고
    • Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats
    • Murray, A. J., Knight, N. S., Little, S. E., Cochlin, L. E., Clements, M., and Clarke, K. (2011) Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats. Nutr. Metab. (Lond.) 8, 55
    • (2011) Nutr. Metab. (Lond.) , vol.8 , pp. 55
    • Murray, A.J.1    Knight, N.S.2    Little, S.E.3    Cochlin, L.E.4    Clements, M.5    Clarke, K.6
  • 44
    • 84949098610 scopus 로고    scopus 로고
    • Re-examining high-fat diets for sports performance: Did we call the 'nail in the coffin' too soon?
    • Burke, L. M. (2015) Re-examining high-fat diets for sports performance: did we call the 'nail in the coffin' too soon? Sports Med. 45, S33-S49
    • (2015) Sports Med. , vol.45 , pp. S33-S49
    • Burke, L.M.1
  • 45
    • 33644829942 scopus 로고    scopus 로고
    • "Fat adaptation" for athletic performance: The nail in the coffin?
    • Burke, L. M., and Kiens, B. (2006) "Fat adaptation" for athletic performance: the nail in the coffin? J. Appl. Physiol. 100, 7-8
    • (2006) J. Appl. Physiol. , vol.100 , pp. 7-8
    • Burke, L.M.1    Kiens, B.2
  • 46
    • 84942933438 scopus 로고    scopus 로고
    • Ketogenic diets for fat loss and exercise performance: Benefits and safety?
    • Kiens, B., and Astrup, A. (2015) Ketogenic diets for fat loss and exercise performance: benefits and safety? Exerc. Sport Sci. Rev. 43, 109
    • (2015) Exerc. Sport Sci. Rev. , vol.43 , pp. 109
    • Kiens, B.1    Astrup, A.2
  • 48
    • 78349235793 scopus 로고    scopus 로고
    • Metabolic factors limiting performance in marathon runners
    • Rapoport, B. I. (2010) Metabolic factors limiting performance in marathon runners. PLOS Comput. Biol. 6, e1000960
    • (2010) PLOS Comput. Biol. , vol.6 , pp. e1000960
    • Rapoport, B.I.1
  • 51
    • 84943527056 scopus 로고    scopus 로고
    • Mitochondrial biogenesis and dynamics in the developing and diseased heart
    • Dorn II, G. W., Vega, R. B., and Kelly, D. P. (2015) Mitochondrial biogenesis and dynamics in the developing and diseased heart. Genes Dev. 29, 1981-1991
    • (2015) Genes Dev. , vol.29 , pp. 1981-1991
    • Dorn, G.W.1    Vega, R.B.2    Kelly, D.P.3
  • 52
    • 35848955451 scopus 로고    scopus 로고
    • Return to the fetal gene programprotects the stressed heart: A strong hypothesis
    • Rajabi, M., Kassiotis, C., Razeghi, P., and Taegtmeyer, H. (2007) Return to the fetal gene programprotects the stressed heart: a strong hypothesis. Heart Fail. Rev. 12, 331-343
    • (2007) Heart Fail. Rev. , vol.12 , pp. 331-343
    • Rajabi, M.1    Kassiotis, C.2    Razeghi, P.3    Taegtmeyer, H.4
  • 53
    • 0031963606 scopus 로고    scopus 로고
    • Free fatty acid kinetics and oxidation in congestive heart failure
    • Lommi, J., Kupari, M., and Yki-Järvinen, H. (1998) Free fatty acid kinetics and oxidation in congestive heart failure. Am. J. Cardiol. 81, 45-50
    • (1998) Am. J. Cardiol. , vol.81 , pp. 45-50
    • Lommi, J.1    Kupari, M.2    Yki-Järvinen, H.3
  • 55
    • 34547590901 scopus 로고    scopus 로고
    • Metabolic mechanisms in heart failure
    • Ashrafian, H., Frenneaux, M. P., and Opie, L. H. (2007) Metabolic mechanisms in heart failure. Circulation 116, 434-448
    • (2007) Circulation , vol.116 , pp. 434-448
    • Ashrafian, H.1    Frenneaux, M.P.2    Opie, L.H.3
  • 57
    • 33947239659 scopus 로고    scopus 로고
    • Thefailingheart-an engine outof fuel
    • Neubauer, S. (2007) Thefailingheart-an engine outof fuel. N. Engl. J. Med. 356, 1140-1151
    • (2007) N. Engl. J. Med. , vol.356 , pp. 1140-1151
    • Neubauer, S.1
  • 62
    • 84875253158 scopus 로고    scopus 로고
    • A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease
    • Kashiwaya, Y., Bergman, C., Lee, J. H., Wan, R., King, M. T., Mughal, M. R., Okun, E., Clarke, K., Mattson, M. P., and Veech, R. L. (2013) A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease. Neurobiol. Aging 34, 1530-1539
    • (2013) Neurobiol. Aging , vol.34 , pp. 1530-1539
    • Kashiwaya, Y.1    Bergman, C.2    Lee, J.H.3    Wan, R.4    King, M.T.5    Mughal, M.R.6    Okun, E.7    Clarke, K.8    Mattson, M.P.9    Veech, R.L.10
  • 63
    • 84922709891 scopus 로고    scopus 로고
    • A new way to produce hyperketonemia: Use of ketone ester in a case of Alzheimer's disease
    • Newport, M. T., VanItallie, T. B., Kashiwaya, Y., King, M. T., and Veech, R. L. (2015) A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease. Alzheimers Dement. 11, 99-103
    • (2015) Alzheimers Dement. , vol.11 , pp. 99-103
    • Newport, M.T.1    VanItallie, T.B.2    Kashiwaya, Y.3    King, M.T.4    Veech, R.L.5
  • 64
    • 84855898777 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore provides a key to the diagnosis and treatment of traumatic brain injury
    • Veech, R. L., Valeri, C. R., and VanItallie, T. B. (2012) The mitochondrial permeability transition pore provides a key to the diagnosis and treatment of traumatic brain injury. IUBMB Life 64, 203-207
    • (2012) IUBMB Life , vol.64 , pp. 203-207
    • Veech, R.L.1    Valeri, C.R.2    VanItallie, T.B.3
  • 65
    • 33644621221 scopus 로고    scopus 로고
    • Fasting versus gradual initiation of the ketogenic diet: A prospective, randomized clinical trial of efficacy
    • Bergqvist, A. G., Schall, J. I., Gallagher, P. R., Cnaan, A., and Stallings, V. A. (2005) Fasting versus gradual initiation of the ketogenic diet: a prospective, randomized clinical trial of efficacy. Epilepsia 46, 1810-1819
    • (2005) Epilepsia , vol.46 , pp. 1810-1819
    • Bergqvist, A.G.1    Schall, J.I.2    Gallagher, P.R.3    Cnaan, A.4    Stallings, V.A.5
  • 67
    • 0030862656 scopus 로고    scopus 로고
    • Substrate signaling by insulin: A ketone bodies ratiomimics insulin action in heart
    • Kashiwaya, Y., King, M.T., and Veech, R. L. (1997) Substrate signaling by insulin: a ketone bodies ratiomimics insulin action in heart. Am. J. Cardiol. 80(3A), 50A-64A
    • (1997) Am. J. Cardiol. , vol.80 , Issue.3 A , pp. 50A-64A
    • Kashiwaya, Y.1    King, M.T.2    Veech, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.