Effect of isoproterenol on myocardial perfusion, function, energy metabolism and nitric oxide pathway in the rat heart - a longitudinal MR study

NMR in Biomedicine

Volumn 27, Issue 5, 2014, Pages 529-538

  Desrois, Martine ^a   Kober, Frank ^a   Lan, Carole ^a   Dalmasso, Christiane ^a   Cole, Mark ^b   Clarke, Kieran ^b   Cozzone, Patrick J ^a   Bernard, Monique ^a  

^a CNRS   (France)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cine MRI; Function; Heart; Isoproterenol; Metabolism; Nitric oxide pathway; Perfusion; Rat

Indexed keywords

FUNCTIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; NITRIC OXIDE; PATHOLOGY; RATING; RATS;

ARTERIAL SPIN LABELING; CINE-MRI; ISOPROTERENOL; LEFT VENTRICULAR MASS; MORPHOLOGICAL CHANGES; PERFUSION; SIMULTANEOUS MEASUREMENT; TIME-DEPENDENT CHANGES;

HEART;

ADENOSINE TRIPHOSPHATE; CREATINE; CREATINE PHOSPHATE; DRUG VEHICLE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ISOPRENALINE; MALONALDEHYDE; NITRIC OXIDE; ADENINE NUCLEOTIDE; CASPASE 3; CREATINE KINASE; LACTATE DEHYDROGENASE; NITRIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CELL PH; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG EFFICACY; ENERGY METABOLISM; EX VIVO STUDY; HEART CONTRACTION; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE MASS; HEART MUSCLE BLOOD FLOW; HEART MUSCLE PERFUSION; HEART VENTRICLE HYPERTROPHY; HIGH ENERGY PHOSPHATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; ISOLATED HEART; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROMETER; OSMOTIC PUMP; OXIDATIVE STRESS; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRE-CLINICAL IMAGING DEVICE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REDUCTION; SPIN LABELING; TISSUE STRUCTURE; UPREGULATION; ANIMAL; CORONARY ARTERY BLOOD FLOW; DIASTOLE; DRUG EFFECTS; ENZYMOLOGY; HEART MUSCLE; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYSTOLE; WISTAR RAT;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

ADENINE NUCLEOTIDES; ANIMALS; CARDIAC OUTPUT; CASPASE 3; CORONARY CIRCULATION; CREATINE; CREATINE KINASE; DIASTOLE; ENERGY METABOLISM; HEART RATE; ISOPROTERENOL; L-LACTATE DEHYDROGENASE; MAGNETIC RESONANCE IMAGING, CINE; MALE; MALONDIALDEHYDE; MYOCARDIUM; NITRATES; NITRIC OXIDE; PERFUSION; RATS, WISTAR; SIGNAL TRANSDUCTION; STROKE VOLUME; SYSTOLE;

EID: 84897960311     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.3088     Document Type: Article

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