-
1
-
-
84976865494
-
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
-
Southan C, Sharman JL, Benson HE, Faccenda E, Pawson AJ, Alexander SP, et al. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucl Acids Res 2016; 44 (Database Issue): D1054–D1068.
-
(2016)
Nucl Acids Res
, vol.44
, Issue.Database Issue
, pp. D1054-D1068
-
-
Southan, C.1
Sharman, J.L.2
Benson, H.E.3
Faccenda, E.4
Pawson, A.J.5
Alexander, S.P.6
-
2
-
-
84949801835
-
The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors
-
Alexander SPH, Davenport AP, Kelly E, Marrion N, Peters JA, Benson HE, et al. The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors. Br J Pharmacol 2015; 172: 5744–5869.
-
(2015)
Br J Pharmacol
, vol.172
, pp. 5744-5869
-
-
Alexander, S.P.H.1
Davenport, A.P.2
Kelly, E.3
Marrion, N.4
Peters, J.A.5
Benson, H.E.6
-
3
-
-
77957325778
-
Novel lipid mediators and resolution mechanisms in acute inflammation: to resolve or not?
-
Serhan CN. Novel lipid mediators and resolution mechanisms in acute inflammation: to resolve or not? Am J Pathol 2010; 177: 1576–1591.
-
(2010)
Am J Pathol
, vol.177
, pp. 1576-1591
-
-
Serhan, C.N.1
-
5
-
-
84961761119
-
Resolution of inflammation: a new therapeutic frontier
-
Fullerton JN, Gilroy DW. Resolution of inflammation: a new therapeutic frontier. Nat Rev Drug Discov 2016; 15: 551–567.
-
(2016)
Nat Rev Drug Discov
, vol.15
, pp. 551-567
-
-
Fullerton, J.N.1
Gilroy, D.W.2
-
7
-
-
34248196011
-
New mechanism for an old drug: aspirin triggers anti-inflammatory lipid mediators with gender implications
-
Chiang N, Serhan CN. New mechanism for an old drug: aspirin triggers anti-inflammatory lipid mediators with gender implications. Compr Ther 2006; 32: 150–157.
-
(2006)
Compr Ther
, vol.32
, pp. 150-157
-
-
Chiang, N.1
Serhan, C.N.2
-
8
-
-
58149094363
-
Annexin A1 and glucocorticoids as effectors of the resolution of inflammation
-
Perretti M, D'Acquisto F. Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat Rev Immunol 2009; 9: 62–70.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 62-70
-
-
Perretti, M.1
D'Acquisto, F.2
-
9
-
-
3042856569
-
A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands
-
Kostenis E. A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands. Pharmacol Ther 2004; 102: 243–257.
-
(2004)
Pharmacol Ther
, vol.102
, pp. 243-257
-
-
Kostenis, E.1
-
10
-
-
84904596809
-
Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7
-
Back M, Powell WS, Dahlen SE, Drazen JM, Evans JF, Serhan CN, et al. Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7. Br J Pharmacol 2014; 171: 3551–3574.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 3551-3574
-
-
Back, M.1
Powell, W.S.2
Dahlen, S.E.3
Drazen, J.M.4
Evans, J.F.5
Serhan, C.N.6
-
11
-
-
33751211223
-
Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses
-
Migeotte I, Communi D, Parmentier M. Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses. Cytokine Growth Factor Rev 2006; 17: 501–519.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 501-519
-
-
Migeotte, I.1
Communi, D.2
Parmentier, M.3
-
12
-
-
84879091724
-
Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor
-
Dalli J, Consalvo AP, Ray V, Di Filippo C, D'Amico M, Mehta N, et al. Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor. J Immunol 2013; 190: 6478–6487.
-
(2013)
J Immunol
, vol.190
, pp. 6478-6487
-
-
Dalli, J.1
Consalvo, A.P.2
Ray, V.3
Di Filippo, C.4
D'Amico, M.5
Mehta, N.6
-
13
-
-
84864743193
-
Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis
-
Vago JP, Nogueira CR, Tavares LP, Soriani FM, Lopes F, Russo RC, et al. Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis. J Leukoc Biol 2012; 92: 249–258.
-
(2012)
J Leukoc Biol
, vol.92
, pp. 249-258
-
-
Vago, J.P.1
Nogueira, C.R.2
Tavares, L.P.3
Soriani, F.M.4
Lopes, F.5
Russo, R.C.6
-
14
-
-
77951902950
-
Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation
-
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, et al. Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation. J Immunol 2010; 184: 2611–2619.
-
(2010)
J Immunol
, vol.184
, pp. 2611-2619
-
-
Dufton, N.1
Hannon, R.2
Brancaleone, V.3
Dalli, J.4
Patel, H.B.5
Gray, M.6
-
15
-
-
0037441872
-
Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R
-
He R, Sang H, Ye RD. Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R. Blood 2003; 101: 1572–1581.
-
(2003)
Blood
, vol.101
, pp. 1572-1581
-
-
He, R.1
Sang, H.2
Ye, R.D.3
-
16
-
-
84898927023
-
A membrane-tethering pepducin that inhibits formyl peptide receptor 2-induced signaling
-
Lee HY, Kim H, Lee SY, Jung YS, Kim SD, Bae YS. A membrane-tethering pepducin that inhibits formyl peptide receptor 2-induced signaling. Pharmazie 2014; 69: 293–296.
-
(2014)
Pharmazie
, vol.69
, pp. 293-296
-
-
Lee, H.Y.1
Kim, H.2
Lee, S.Y.3
Jung, Y.S.4
Kim, S.D.5
Bae, Y.S.6
-
17
-
-
0029094562
-
Assessment of dose proportionality: report from the statisticians in the Pharmaceutical Industry/Pharmacokinetics UK Joint Working Party
-
Gough K, Hutchison M, Keene O, Byrom B, Ellis S, Lacey L, et al. Assessment of dose proportionality: report from the statisticians in the Pharmaceutical Industry/Pharmacokinetics UK Joint Working Party. Ther Innov Regul Sci 1995; 29: 1039–1048.
-
(1995)
Ther Innov Regul Sci
, vol.29
, pp. 1039-1048
-
-
Gough, K.1
Hutchison, M.2
Keene, O.3
Byrom, B.4
Ellis, S.5
Lacey, L.6
-
18
-
-
84861418098
-
LPS challenge in healthy subjects: an investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2
-
Aul R, Patel S, Summerhill S, Kilty I, Plumb J, Singh D. LPS challenge in healthy subjects: an investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2. Int Immunopharmacol 2012; 13: 225–231.
-
(2012)
Int Immunopharmacol
, vol.13
, pp. 225-231
-
-
Aul, R.1
Patel, S.2
Summerhill, S.3
Kilty, I.4
Plumb, J.5
Singh, D.6
-
19
-
-
84976307749
-
Pharmacokinetic/pharmacodynamic modelling of receptor internalization with CRTH2 antagonists to optimize dose selection
-
Krause A, Zisowsky J, Strasser DS, Gehin M, Sidharta PN, Groenen PM, et al. Pharmacokinetic/pharmacodynamic modelling of receptor internalization with CRTH2 antagonists to optimize dose selection. Clin Pharmacokinet 2016; 55: 813–821.
-
(2016)
Clin Pharmacokinet
, vol.55
, pp. 813-821
-
-
Krause, A.1
Zisowsky, J.2
Strasser, D.S.3
Gehin, M.4
Sidharta, P.N.5
Groenen, P.M.6
-
20
-
-
78649338158
-
FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis
-
Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M, et al. FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis. FASEB J 2010; 24: 4240–4249.
-
(2010)
FASEB J
, vol.24
, pp. 4240-4249
-
-
Maderna, P.1
Cottell, D.C.2
Toivonen, T.3
Dufton, N.4
Dalli, J.5
Perretti, M.6
-
22
-
-
84876004456
-
Distinct signaling cascades elicited by different formyl peptide receptor 2 (FPR2) agonists
-
Cattaneo F, Parisi M, Ammendola R. Distinct signaling cascades elicited by different formyl peptide receptor 2 (FPR2) agonists. Int J Mol Sci 2013; 14: 7193–7230.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 7193-7230
-
-
Cattaneo, F.1
Parisi, M.2
Ammendola, R.3
-
23
-
-
33646938805
-
Transient and chronic neutropenias detected in children with different viral and bacterial infections
-
Karavanaki K, Polychronopoulou S, Giannaki M, Haliotis F, Sider B, Brisimitzi M, et al. Transient and chronic neutropenias detected in children with different viral and bacterial infections. Acta Paediatr 2006; 95: 565–572.
-
(2006)
Acta Paediatr
, vol.95
, pp. 565-572
-
-
Karavanaki, K.1
Polychronopoulou, S.2
Giannaki, M.3
Haliotis, F.4
Sider, B.5
Brisimitzi, M.6
-
24
-
-
84922212387
-
Plasma levels of IL-37 and correlation with TNF-alpha, IL-17 A, and disease activity during DMARD treatment of rheumatoid arthritis
-
Zhao PW, Jiang WG, Wang L, Jiang ZY, Shan YX, Jiang YF. Plasma levels of IL-37 and correlation with TNF-alpha, IL-17 A, and disease activity during DMARD treatment of rheumatoid arthritis. PLoS One 2014; 9: e95346.
-
(2014)
PLoS One
, vol.9
-
-
Zhao, P.W.1
Jiang, W.G.2
Wang, L.3
Jiang, Z.Y.4
Shan, Y.X.5
Jiang, Y.F.6
-
25
-
-
84926023016
-
An enhanced ELISPOT assay for sensitive detection of antigen-specific T cell responses to Borrelia burgdorferi
-
Jin C, Roen DR, Lehmann PV, Kellermann GH. An enhanced ELISPOT assay for sensitive detection of antigen-specific T cell responses to Borrelia burgdorferi. Cells 2013; 2: 607–620.
-
(2013)
Cells
, vol.2
, pp. 607-620
-
-
Jin, C.1
Roen, D.R.2
Lehmann, P.V.3
Kellermann, G.H.4
-
26
-
-
84890290253
-
Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist
-
Leaker BR, Barnes PJ, O'Connor B. Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist. Respir Res 2013; 14: 137.
-
(2013)
Respir Res
, vol.14
, pp. 137
-
-
Leaker, B.R.1
Barnes, P.J.2
O'Connor, B.3
-
27
-
-
69249202368
-
Agonist-specific patterns of beta 2-adrenoceptor responses in human airway cells during prolonged exposure
-
Duringer C, Grundstrom G, Gurcan E, Dainty IA, Lawson M, Korn SH, et al. Agonist-specific patterns of beta 2-adrenoceptor responses in human airway cells during prolonged exposure. Br J Pharmacol 2009; 158: 169–179.
-
(2009)
Br J Pharmacol
, vol.158
, pp. 169-179
-
-
Duringer, C.1
Grundstrom, G.2
Gurcan, E.3
Dainty, I.A.4
Lawson, M.5
Korn, S.H.6
-
28
-
-
66149149851
-
Structure-based discovery of beta2-adrenergic receptor ligands
-
Kolb P, Rosenbaum DM, Irwin JJ, Fung JJ, Kobilka BK, Shoichet BK. Structure-based discovery of beta2-adrenergic receptor ligands. Proc Natl Acad Sci U S A 2009; 106: 6843–6848.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 6843-6848
-
-
Kolb, P.1
Rosenbaum, D.M.2
Irwin, J.J.3
Fung, J.J.4
Kobilka, B.K.5
Shoichet, B.K.6
-
29
-
-
79955631465
-
Agonist-directed desensitization of the beta2-adrenergic receptor
-
Goral V, Jin Y, Sun H, Ferrie AM, Wu Q, Fang Y. Agonist-directed desensitization of the beta2-adrenergic receptor. PLoS One 2011; 6: e19282.
-
(2011)
PLoS One
, vol.6
-
-
Goral, V.1
Jin, Y.2
Sun, H.3
Ferrie, A.M.4
Wu, Q.5
Fang, Y.6
-
30
-
-
78751498756
-
Functional selectivity and biased receptor signaling
-
Kenakin T. Functional selectivity and biased receptor signaling. J Pharmacol Exp Ther 2011; 336: 296–302.
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 296-302
-
-
Kenakin, T.1
-
31
-
-
77952354490
-
Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery
-
Kenakin T, Miller LJ. Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery. Pharmacol Rev 2010; 62: 265–304.
-
(2010)
Pharmacol Rev
, vol.62
, pp. 265-304
-
-
Kenakin, T.1
Miller, L.J.2
-
32
-
-
84873685831
-
Molecular signatures of G-protein-coupled receptors
-
Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM. Molecular signatures of G-protein-coupled receptors. Nature 2013; 494: 185–194.
-
(2013)
Nature
, vol.494
, pp. 185-194
-
-
Venkatakrishnan, A.J.1
Deupi, X.2
Lebon, G.3
Tate, C.G.4
Schertler, G.F.5
Babu, M.M.6
-
33
-
-
33845903110
-
Functional selectivity and classical concepts of quantitative pharmacology
-
Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, et al. Functional selectivity and classical concepts of quantitative pharmacology. J Pharmacol Exp Ther 2007; 320: 1–13.
-
(2007)
J Pharmacol Exp Ther
, vol.320
, pp. 1-13
-
-
Urban, J.D.1
Clarke, W.P.2
von Zastrow, M.3
Nichols, D.E.4
Kobilka, B.5
Weinstein, H.6
-
34
-
-
66249144426
-
The structure and function of G-protein-coupled receptors
-
Rosenbaum DM, Rasmussen SG, Kobilka BK. The structure and function of G-protein-coupled receptors. Nature 2009; 459: 356–363.
-
(2009)
Nature
, vol.459
, pp. 356-363
-
-
Rosenbaum, D.M.1
Rasmussen, S.G.2
Kobilka, B.K.3
|