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Volumn 2, Issue 3, 2013, Pages 607-620

An enhanced ELISPOT assay for sensitive detection of antigen-specific T cell responses to Borrelia burgdorferi

Author keywords

Borrelia infection; ELISPOT; Interferon ; T cells

Indexed keywords

GAMMA INTERFERON;

EID: 84926023016     PISSN: None     EISSN: 20734409     Source Type: Journal    
DOI: 10.3390/cells2030607     Document Type: Article
Times cited : (26)

References (41)
  • 2
    • 0035849985 scopus 로고    scopus 로고
    • Lyme disease
    • Steere, A.C. Lyme disease. N. Engl. J. Med. 2001, 345, 115-125.
    • (2001) N. Engl. J. Med , vol.345 , pp. 115-125
    • Steere, A.C.1
  • 4
    • 85135970231 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention
    • Available online, accessed on 1 July
    • Centers for Disease Control and Prevention. Reported Cases of Lyme Disease by Year, United States, 2002-2011. Available online: http://www.cdc.gov/lyme/stats/chartstables/casesbyyear.html (accessed on 1 July 2013).
    • (2013) Reported Cases of Lyme Disease By Year, United States, 2002-2011
  • 5
    • 0032574936 scopus 로고    scopus 로고
    • Underreporting of Lyme disease
    • Young, J.D. Underreporting of Lyme disease. N. Engl. J. Med. 1998, 338, 1629.
    • (1998) N. Engl. J. Med , vol.338 , pp. 1629
    • Young, J.D.1
  • 6
    • 0033789898 scopus 로고    scopus 로고
    • Cellular and molecular aspects of Lyme arthritis
    • Gross, D.M.; Huber, B.T. Cellular and molecular aspects of Lyme arthritis. Cell. Mol. Life Sci. 2000, 57, 1562-1569.
    • (2000) Cell. Mol. Life Sci , vol.57 , pp. 1562-1569
    • Gross, D.M.1    Huber, B.T.2
  • 7
    • 0028916091 scopus 로고
    • Borrelia burgdorferi-specific T lymphocytes induce severe destructive Lyme arthritis
    • Lim, L.C.; England, D.M.; DuChateau, B.K.; Glowacki, N.J.; Schell, R.F. Borrelia burgdorferi-specific T lymphocytes induce severe destructive Lyme arthritis. Infect. Immun. 1995, 63, 1400-1408.
    • (1995) Infect. Immun , vol.63 , pp. 1400-1408
    • Lim, L.C.1    England, D.M.2    Duchateau, B.K.3    Glowacki, N.J.4    Schell, R.F.5
  • 9
    • 84859935020 scopus 로고    scopus 로고
    • A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi
    • Ramesh, G.; Benge, S.; Pahar, B.; Philipp, M.T. A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi. J. Neuroinflammation 2012, 9, 72.
    • (2012) J. Neuroinflammation , vol.9 , pp. 72
    • Ramesh, G.1    Benge, S.2    Pahar, B.3    Philipp, M.T.4
  • 11
    • 0023767530 scopus 로고
    • Specific immune responses in Lyme borreliosis. Characterization of T cell and B cell responses to Borrelia burgdorferi
    • Dattwyler, R.J.; Volkman, D.J.; Halperin, J.J.; Luft, B.J.; Thomas, J.; Golightly, M.G. Specific immune responses in Lyme borreliosis. Characterization of T cell and B cell responses to Borrelia burgdorferi. Ann. N. Y. Acad. Sci. 1988, 539, 93-102.
    • (1988) Ann. N. Y. Acad. Sci , vol.539 , pp. 93-102
    • Dattwyler, R.J.1    Volkman, D.J.2    Halperin, J.J.3    Luft, B.J.4    Thomas, J.5    Golightly, M.G.6
  • 12
    • 0026760468 scopus 로고
    • Cellular immune reactivity to recombinant OspA and flagellin from Borrelia burgdorferi in patients with Lyme borreliosis. Complexity of humoral and cellular immune responses
    • Krause, A.; Burmester, G.R.; Rensing, A.; Schoerner, C.; Schaible, U.E.; Simon, M.M.; Herzer, P.; Kramer, M.D.; Wallich, R. Cellular immune reactivity to recombinant OspA and flagellin from Borrelia burgdorferi in patients with Lyme borreliosis. Complexity of humoral and cellular immune responses. J. Clin. Invest. 1992, 90, 1077-1084.
    • (1992) J. Clin. Invest , vol.90 , pp. 1077-1084
    • Krause, A.1    Burmester, G.R.2    Rensing, A.3    Schoerner, C.4    Schaible, U.E.5    Simon, M.M.6    Herzer, P.7    Kramer, M.D.8    Wallich, R.9
  • 14
    • 84869118537 scopus 로고    scopus 로고
    • High frequency of false positive IgM immunoblots for Borrelia burgdorferi in clinical practice
    • Seriburi, V.; Ndukwe, N.; Chang, Z.; Cox, M.E.; Wormser, G.P. High frequency of false positive IgM immunoblots for Borrelia burgdorferi in clinical practice. Clin. Microbiol. Infect. 2012, 18, 1236-1240.
    • (2012) Clin. Microbiol. Infect , vol.18 , pp. 1236-1240
    • Seriburi, V.1    Ndukwe, N.2    Chang, Z.3    Cox, M.E.4    Wormser, G.P.5
  • 15
    • 0344731049 scopus 로고    scopus 로고
    • Role of serology in the diagnosis of Lyme disease
    • Brown, S.L.; Hansen, S.L.; Langone, J.J. Role of serology in the diagnosis of Lyme disease. JAMA 1999, 282, 62-66.
    • (1999) JAMA , vol.282 , pp. 62-66
    • Brown, S.L.1    Hansen, S.L.2    Langone, J.J.3
  • 16
    • 0035283036 scopus 로고    scopus 로고
    • New method for detection of Borrelia burgdorferi antigen complexed to antibody in seronegative Lyme disease
    • Brunner, M. New method for detection of Borrelia burgdorferi antigen complexed to antibody in seronegative Lyme disease. J. Immunol. Methods. 2001, 249, 185-190.
    • (2001) J. Immunol. Methods , vol.249 , pp. 185-190
    • Brunner, M.1
  • 17
    • 0037205676 scopus 로고    scopus 로고
    • Limitation of serological testing for Lyme borreliosis: Evaluation of ELISA and western blot in comparison with PCR and culture methods
    • Tylewska-Wierzbanowska, S.; Chmielewski, T. Limitation of serological testing for Lyme borreliosis: evaluation of ELISA and western blot in comparison with PCR and culture methods. Wien. Klin. Wochenschr. 2002, 114, 601-605.
    • (2002) Wien. Klin. Wochenschr , vol.114 , pp. 601-605
    • Tylewska-Wierzbanowska, S.1    Chmielewski, T.2
  • 18
    • 0029131745 scopus 로고
    • The outer surface proteins of Lyme disease borrelia spirochetes stimulate T cells to secrete interferon-gamma (IFN-gamma): Diagnostic and pathogenic implications
    • Forsberg, P.; Ernerudh, J.; Ekerfelt, C.; Roberg, M.; Vrethem, M.; Bergstrom, S. The outer surface proteins of Lyme disease borrelia spirochetes stimulate T cells to secrete interferon-gamma (IFN-gamma): Diagnostic and pathogenic implications. Clin. Exp. Immunol. 1995, 101, 453-460.
    • (1995) Clin. Exp. Immunol , vol.101 , pp. 453-460
    • Forsberg, P.1    Ernerudh, J.2    Ekerfelt, C.3    Roberg, M.4    Vrethem, M.5    Bergstrom, S.6
  • 21
    • 0029656118 scopus 로고    scopus 로고
    • Evolution of the serologic response to Borrelia burgdorferi in treated patients with culture-confirmed erythema migrans
    • Aguero-Rosenfeld, M.E.; Nowakowski, J.; Bittker, S.; Cooper, D.; Nadelman, R.B.; Wormser, G.P. Evolution of the serologic response to Borrelia burgdorferi in treated patients with culture-confirmed erythema migrans. J. Clin. Microbiol. 1996, 34, 1-9.
    • (1996) J. Clin. Microbiol , vol.34 , pp. 1-9
    • Aguero-Rosenfeld, M.E.1    Nowakowski, J.2    Bittker, S.3    Cooper, D.4    Nadelman, R.B.5    Wormser, G.P.6
  • 22
    • 0025995457 scopus 로고
    • The T-cell proliferative assay in the diagnosis of Lyme disease
    • Dressler, F.; Yoshinari, N.H.; Steere, A.C. The T-cell proliferative assay in the diagnosis of Lyme disease. Ann. Intern. Med. 1991, 115, 533-539.
    • (1991) Ann. Intern. Med , vol.115 , pp. 533-539
    • Dressler, F.1    Yoshinari, N.H.2    Steere, A.C.3
  • 24
    • 0023736053 scopus 로고
    • Seronegative Lyme disease. Dissociation of specific T-and B-lymphocyte responses to Borrelia burgdorferi
    • Dattwyler, R.J.; Volkman, D.J.; Luft, B.J.; Halperin, J.J.; Thomas, J.; Golightly, M.G. Seronegative Lyme disease. Dissociation of specific T-and B-lymphocyte responses to Borrelia burgdorferi. N. Engl. J. Med. 1988, 319, 1441-1446.
    • (1988) N. Engl. J. Med , vol.319 , pp. 1441-1446
    • Dattwyler, R.J.1    Volkman, D.J.2    Luft, B.J.3    Halperin, J.J.4    Thomas, J.5    Golightly, M.G.6
  • 25
    • 0030614677 scopus 로고    scopus 로고
    • Temporal study of immunoglobin M seroreactivity to Borrelia burgdorferi in patients treated for Lyme borreliosis
    • Hilton, E.; Tramontano, A.; DeVoti, J.; Sood, S.K. Temporal study of immunoglobin M seroreactivity to Borrelia burgdorferi in patients treated for Lyme borreliosis. J. Clin. Microbiol. 1997, 35, 774-776.
    • (1997) J. Clin. Microbiol , vol.35 , pp. 774-776
    • Hilton, E.1    Tramontano, A.2    Devoti, J.3    Sood, S.K.4
  • 26
    • 0035885047 scopus 로고    scopus 로고
    • Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease
    • Kalish, R.A.; McHugh, G.; Granquist, J.; Shea, B.; Ruthazer, R.; Steere, A.C. Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease. Clin. Infect. Dis. 2001, 33, 780-785.
    • (2001) Clin. Infect. Dis , vol.33 , pp. 780-785
    • Kalish, R.A.1    McHugh, G.2    Granquist, J.3    Shea, B.4    Ruthazer, R.5    Steere, A.C.6
  • 27
    • 80555129219 scopus 로고    scopus 로고
    • Combining ELISPOT and ELISA to measure amounts of cytokines secreted by a single cell
    • 2nd ed.; Kalyuzhny, A., Ed.; Springer Science+Business Media, LLC: New York, NY, USA
    • Hagen, J.; Houchins, J.P.; Kalyuzhny, A.E. Combining ELISPOT and ELISA to measure amounts of cytokines secreted by a single cell. In Handbook of ELISPOT: Methods and Protocols, Methods in Molecular Biology, 2nd ed.; Kalyuzhny, A., Ed.; Springer Science+Business Media, LLC: New York, NY, USA, 2012; Volume 792, pp.115-122.
    • (2012) Handbook of ELISPOT: Methods and Protocols, Methods In Molecular Biology , vol.792 , pp. 115-122
    • Hagen, J.1    Houchins, J.P.2    Kalyuzhny, A.E.3
  • 28
    • 80555139568 scopus 로고    scopus 로고
    • Unique Strengths of ELISPOT for T Cell Diagnostics
    • 2nd ed.; Kalyuzhny, A., Ed.; Springer Science+Business Media, LLC: New York, NY, USA
    • Lehmann, P.V.; Zhang, W. Unique Strengths of ELISPOT for T Cell Diagnostics. In Handbook of ELISPOT: Methods and Protocols, Methods in Molecular Biology, 2nd ed.; Kalyuzhny, A., Ed.; Springer Science+Business Media, LLC: New York, NY, USA, 2012; Volume 792, pp. 3-23.
    • (2012) Handbook of ELISPOT: Methods and Protocols, Methods In Molecular Biology , vol.792 , pp. 3-23
    • Lehmann, P.V.1    Zhang, W.2
  • 29
    • 84889342332 scopus 로고    scopus 로고
    • Validating Reference Samples for Comparison in a Regulated ELISPOT Assay
    • 1st ed.; Prabhakar, U., Kelley, M., Eds.; John Wiley & Sons, Ltd.: West Sussex, UK
    • Tary-Lehmann, M.; Hamm, C.D.; Lehmann, P.V. Validating Reference Samples for Comparison in a Regulated ELISPOT Assay. In Validation of Cell-Based Assays in the GLP Setting: A Practical Guide, 1st ed.; Prabhakar, U., Kelley, M., Eds.; John Wiley & Sons, Ltd.: West Sussex, UK, 2008; pp. 127-146.
    • (2008) Validation of Cell-Based Assays In the GLP Setting: A Practical Guide , pp. 127-146
    • Tary-Lehmann, M.1    Hamm, C.D.2    Lehmann, P.V.3
  • 30
    • 0035938954 scopus 로고    scopus 로고
    • Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells
    • Lalvani, A.; Pathan, A.A.; Durkan, H.; Wilkinson, K.A.; Whelan, A.; Deeks, J.J.; Reece, W.H.; Latif, M.; Pasvol, G.; Hill, A.V. Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. Lancet 2001, 357, 2017-2021.
    • (2001) Lancet , vol.357 , pp. 2017-2021
    • Lalvani, A.1    Pathan, A.A.2    Durkan, H.3    Wilkinson, K.A.4    Whelan, A.5    Deeks, J.J.6    Reece, W.H.7    Latif, M.8    Pasvol, G.9    Hill, A.V.10
  • 31
    • 1442278297 scopus 로고    scopus 로고
    • Counting antigen-specific T cells: A new approach for monitoring response to tuberculosis treatment?
    • Lalvani, A. Counting antigen-specific T cells: A new approach for monitoring response to tuberculosis treatment? Clin. Infect. Dis. 2004, 38, 757-759.
    • (2004) Clin. Infect. Dis , vol.38 , pp. 757-759
    • Lalvani, A.1
  • 32
    • 84890031167 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention, United States, Available online, accessed on 1 July 2013
    • Centers for Disease Control and Prevention. Signs and Symptoms of Lyme Disease, United States. 2013. Available online: http://www.cdc.gov/lyme/signs_symptoms/index.html (accessed on 1 July 2013).
    • (2013) Signs and Symptoms of Lyme Disease
  • 33
    • 33750132121 scopus 로고    scopus 로고
    • The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: Clinical practice guidelines by the Infectious Diseases Society of America
    • Wormser, G.P.; Dattwyler, R.J.; Shapiro, E.D.; Halperin, J.J.; Steere, A.C.; Klempner, M.S.; Krause, P.J.; Bakken, J.S.; Strle, F.; Stanek, G, et al. The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: Clinical practice guidelines by the Infectious Diseases Society of America. Clin. Infect. Dis. 2006, 43, 1089-1134.
    • (2006) Clin. Infect. Dis , vol.43 , pp. 1089-1134
    • Wormser, G.P.1    Dattwyler, R.J.2    Shapiro, E.D.3    Halperin, J.J.4    Steere, A.C.5    Klempner, M.S.6    Krause, P.J.7    Bakken, J.S.8    Strle, F.9    Stanek, G.10
  • 35
    • 2442707597 scopus 로고    scopus 로고
    • Borrelia-Specific interferon-gamma and interleukin-4 secretion in cerebrospinal fluid and blood during Lyme borreliosis in humans: Association with clinical outcome
    • Widhe, M.; Jarefors, S.; Ekerfelt, C.; Vrethem, M.; Bergstrom, S.; Forsberg, P.; Ernerudh, J. Borrelia-Specific interferon-gamma and interleukin-4 secretion in cerebrospinal fluid and blood during Lyme borreliosis in humans: association with clinical outcome. J. Infect. Dis. 2004, 189, 1881-1891.
    • (2004) J. Infect. Dis , vol.189 , pp. 1881-1891
    • Widhe, M.1    Jarefors, S.2    Ekerfelt, C.3    Vrethem, M.4    Bergstrom, S.5    Forsberg, P.6    Ernerudh, J.7
  • 37
    • 85136041278 scopus 로고    scopus 로고
    • Objective, User-Independent ELISPOT Data Analysis Based on Scientifically Validated Principles
    • 1st ed.; Uma Prabhakar, Marian Kelley, Eds.; John Wiley & Sons, Ltd.: West Sussex, UK
    • Zhang, W.; Tary-Lehmann, M. Objective, User-Independent ELISPOT Data Analysis Based on Scientifically Validated Principles. In Validation of Cell-Based Assays in the GLP Setting: A Practical Guide, 1st ed.; Uma Prabhakar, Marian Kelley, Eds.; John Wiley & Sons, Ltd.: West Sussex, UK, 2008; pp. 126-147.
    • (2008) Validation of Cell-Based Assays In the GLP Setting: A Practical Guide , pp. 126-147
    • Zhang, W.1    Tary-Lehmann, M.2
  • 38
    • 0033035214 scopus 로고    scopus 로고
    • Asymptomatic Borrelia-seropositive individuals display the same incidence of Borrelia-specific interferon-gamma (IFN-gamma)-secreting cells in blood as patients with clinical Borrelia infection
    • Ekerfelt, C.; Forsberg, P.; Svenvik, M.; Roberg, M.; Bergstrom, S.; Ernerudh, J. Asymptomatic Borrelia-seropositive individuals display the same incidence of Borrelia-specific interferon-gamma (IFN-gamma)-secreting cells in blood as patients with clinical Borrelia infection. Clin. Exp. Immunol. 1999, 115, 498-502.
    • (1999) Clin. Exp. Immunol , vol.115 , pp. 498-502
    • Ekerfelt, C.1    Forsberg, P.2    Svenvik, M.3    Roberg, M.4    Bergstrom, S.5    Ernerudh, J.6
  • 39
  • 41
    • 59649119240 scopus 로고    scopus 로고
    • Evaluation of Diagnositc Tests
    • Parfrey, P., Barrett, B., Eds.; Humana Press: Totowa, NJ, USA
    • Fardy, J. Evaluation of Diagnositc Tests. In Methods of Molecular Biology, Clinical Epidemiology; Parfrey, P., Barrett, B., Eds.; Humana Press: Totowa, NJ, USA, 2009; Volume 473, pp. 127-136.
    • (2009) Methods of Molecular Biology, Clinical Epidemiology , vol.473 , pp. 127-136
    • Fardy, J.1


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