SOCS3 promotes inflammation and apoptosis via inhibiting JAK2/STAT3 signaling pathway in 3T3-L1 adipocyte

Immunobiology

Volumn 220, Issue 8, 2015, Pages 947-953

  Liu, Zhenjiang ^a   Gan, Lu ^a   Zhou, Zhongjie ^a   Jin, Wei ^a   Sun, Chao ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Adipocyte; Apoptosis; Inflammation; JAK STAT signaling pathway; SOCS3

Indexed keywords

CASPASE 3; CASPASE 9; INTERLEUKIN 6; JANUS KINASE 2; LEPTIN; LIPOPOLYSACCHARIDE; PROTEIN BAX; PROTEIN BCL 2; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA; 8-BENZYL-4-OXO-8-AZABICYCLO(3.2.1)OCT-2-ENE-6,7-DICARBOXYLIC ACID; GAMMA INTERFERON; JAK2 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING; TROPANE DERIVATIVE; TUMOR NECROSIS FACTOR;

3T3 CELL LINE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ADIPOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; APOPTOSIS; CASPASE 3; GENE EXPRESSION REGULATION; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-6; JANUS KINASE 2; LEPTIN; MICE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TROPANES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85001807264     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2015.02.004     Document Type: Article

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