A cell-based approach to characterize antimicrobial compounds through kinetic dose response

Bioorganic and Medicinal Chemistry

Volumn 24, Issue 24, 2016, Pages 6315-6319

  MacNair, Craig R ^a   Stokes, Jonathan M ^a   French, Shawn ^a   Myers, Cullen L ^a   Iyer, Kali R ^a   Brown, Eric D ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Antibiotic discovery; Dose response; High throughput screening; Hit to lead

Indexed keywords

ANTIINFECTIVE AGENT; MOLECULAR LIBRARY;

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CELL BASED KINETIC DOSE RESPONSE CURVE; COST EFFECTIVENESS ANALYSIS; DOSE RESPONSE; DRUG CLASSIFICATION; DRUG DEVELOPMENT; DRUG MECHANISM; DRUG SCREENING; DRUG STABILITY; ESCHERICHIA COLI; INHIBITORY CONCENTRATION; STRUCTURE ACTIVITY RELATION; BACTERIUM; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ECONOMICS; KINETICS; MICROBIAL SENSITIVITY TEST; MOLECULAR LIBRARY; PHARMACOLOGY;

ANTI-BACTERIAL AGENTS; BACTERIA; DOSE-RESPONSE RELATIONSHIP, DRUG; KINETICS; MICROBIAL SENSITIVITY TESTS; SMALL MOLECULE LIBRARIES;

EID: 85001052542     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2016.09.053     Document Type: Article

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