RIPK1 inhibits ZBP1-driven necroptosis during development

Nature

Volumn 540, Issue 7631, 2016, Pages 129-133

  Newton, Kim ^a   Wickliffe, Katherine E ^a   Maltzman, Allie ^a   Dugger, Debra L ^a   Strasser, Andreas ^b,c   Pham, Victoria C ^a   Lill, Jennie R ^a   Roose Girma, Merone ^a   Warming, Søren ^a   Solon, Margaret ^a   Ngu, Hai ^a   Webster, Joshua D ^a   Dixit, Vishva M ^a  

^a GENENTECH INC   (United States)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ASPARAGINE; ASPARTIC ACID; MIXED LINEAGE KINASE; MIXED LINEAGE KINASE LIKE; PHOSPHOTRANSFERASE; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN; RECEPTOR INTERACTING PROTEIN KINASE 1; RECEPTOR INTERACTING PROTEIN KINASE 3; SERINE; THREONINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; Z DNA BINDING PROTEIN 1; CASPASE 8; GLYCOPROTEIN; MLKL PROTEIN, MOUSE; PROTEIN BINDING; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, MOUSE; RIPK3 PROTEIN, MOUSE; TICAM-1 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR; VESICULAR TRANSPORT ADAPTOR PROTEIN; ZBP1 PROTEIN, MOUSE;

APOPTOSIS; GENE EXPRESSION; GENETIC ANALYSIS; INHIBITION; MUTATION; PROTEIN; RODENT; SKIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; AUTOPHOSPHORYLATION; CELL MATURATION; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE LOSS; IN VITRO STUDY; IN VIVO STUDY; LETHALITY; MOUSE; MUTANT; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SKIN; THYMUS; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CYTOLOGY; DEFICIENCY; EMBRYOLOGY; FEMALE; GENETICS; MACROPHAGE; MALE; MAMMALIAN EMBRYO; METABOLISM; MUTATION; NECROSIS; NEWBORN; PHOSPHORYLATION;

MUS;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMINO ACID MOTIFS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CASPASE 8; EMBRYO, MAMMALIAN; FEMALE; GLYCOPROTEINS; MACROPHAGES; MALE; MICE; MUTATION; NECROSIS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85000659718     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature20559     Document Type: Article

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