Unique pathological tau conformers from alzheimer's brains transmit tau pathology in nontransgenic mice

Journal of Experimental Medicine

Volumn 213, Issue 12, 2016, Pages 2635-2654

  Guo, Jing L ^a   Narasimhan, Sneha ^a   Changolkar, Lakshmi ^a   He, Zhuohao ^a   Stieber, Anna ^a   Zhang, Bin ^a   Gathagan, Ronald J ^a   Iba, Michiyo ^a   McBride, Jennifer D ^a   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TAU PROTEIN; HEPARIN; ISOPROTEIN; PROTEIN AGGREGATE; TISSUE EXTRACT;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN REGION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN TRANSPORT; TAUOPATHY; WESTERN BLOTTING; AGING; ANIMAL; BRAIN; C57BL MOUSE; CHEMISTRY; METABOLISM; NERVE CELL; NEUROFIBRILLARY TANGLE; PATHOLOGY; PHOSPHORYLATION; PROTEIN CONFORMATION; TRANSGENIC MOUSE; ULTRASTRUCTURE;

AGING; ALZHEIMER DISEASE; ANIMALS; BRAIN; HEPARIN; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUROFIBRILLARY TANGLES; NEURONS; PHOSPHORYLATION; PROTEIN AGGREGATES; PROTEIN CONFORMATION; PROTEIN ISOFORMS; TAU PROTEINS; TAUOPATHIES; TISSUE EXTRACTS;

EID: 84999766500     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20160833     Document Type: Article

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