Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function

Immunity

Volumn 45, Issue 5, 2016, Pages 975-987

  Thomas, Graham D ^a   Hanna, Richard N ^a   Vasudevan, Neelakatan T ^b   Hamers, Anouk A ^a   Romanoski, Casey E ^c   McArdle, Sara ^a   Ross, Kevin D ^d   Blatchley, Amy ^a   Yoakum, Deborah ^a   Hamilton, Bruce A ^d   Mikulski, Zbigniew ^a   Jain, Mukesh K ^b   Glass, Christopher K ^d   Hedrick, Catherine C ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Keating Bioresearch Building ^*  (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CD135 ANTIGEN; CD14 ANTIGEN; CD16 ANTIGEN; GLYCOPROTEIN P 15095; HISTONE H3; KRUPPEL LIKE FACTOR 2; KRUPPEL LIKE FACTOR 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; NUCLEAR RECEPTOR NUR77; TOLL LIKE RECEPTOR 4; LY ANTIGEN; LY-6C ANTIGEN, MOUSE; NR4A1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; STEADY STATE; TRANSCRIPTION INITIATION SITE; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CELL SEPARATION; CHROMATIN IMMUNOPRECIPITATION; CYTOLOGY; DEFICIENCY; EXPERIMENTAL MELANOMA; IMMUNOLOGY; KNOCKOUT MOUSE; POLYMERASE CHAIN REACTION;

ANIMALS; ANTIGENS, LY; CELL DIFFERENTIATION; CELL SEPARATION; CHROMATIN IMMUNOPRECIPITATION; MACROPHAGES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; POLYMERASE CHAIN REACTION;

EID: 84999723749     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.10.011     Document Type: Article

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