Cardiac adaptation to volume overload

Cardiac Adaptations: Molecular Mechanisms

Volumn 4, Issue , 2013, Pages 167-199

  Melenovsky, Vojtech ^a  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

Aorto caval fistula; Cardiac hypertrophy; Cardiac remodelling; Diastolic function; Experimental models; Heart failure; Hemodynamics; Mitral regurgitation; Systolic function; Volume overload

Indexed keywords

EID: 84999238367     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-5203-4_9     Document Type: Chapter

References (159)

1. Carabello BA (2012) Volume overload. Heart Fail Clin 8:33-42
2. Adler CP, Costabel U (1975) Cell number in human heart in atrophy, hypertrophy, and under the influence of cytostatics. Recent Adv Stud Cardiac Struct Metab 6:343-355
3. Laflamme MA, Murry CE (2011) Heart regeneration. Nature 473:326-335
4. Bergmann O, Bhardwaj RD, Bernard S et al (2009) Evidence for cardiomyocyte renewal in humans. Science 324:98-102
5. Dorn GW 2nd (2007) The fuzzy logic of physiological cardiac hypertrophy. Hypertension 49:962-970
6. Kehat I, Molkentin JD (2010) Molecular pathways underlying cardiac remodeling during pathophysiological stimulation. Circulation 122:2727-2735
7. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP (1990) Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 322:1561-1566
8. Baggish AL, Wood MJ (2011) Athlete's heart and cardiovascular care of the athlete: scientific and clinical update. Circulation 123:2723-2735
9. duManoir GR, Haykowsky MJ, Syrotuik DG, Taylor DA, Bell GJ (2007) The effect of high- intensity rowing and combined strength and endurance training on left ventricular systolic function and morphology. Int J Sports Med 28:488-494
10. Baggish AL, Wang F, Weiner RB et al (2008) Training-specific changes in cardiac structure and function: a prospective and longitudinal assessment of competitive athletes. J Appl Physiol 104:1121-1128
11. Milliken MC, Stray-Gundersen J, Peshock RM, Katz J, Mitchell JH (1988) Left ventricular mass as determined by magnetic resonance imaging in male endurance athletes. Am J Cardiol 62:301-305
12. Baggish AL, Yared K, Wang F et al (2008) The impact of endurance exercise training on left ventricular systolic mechanics. Am J Physiol Heart Circ Physiol 295:H1109-H1116
13. Pelliccia A, Kinoshita N, Pisicchio C, et al. (2010) Long-term clinical consequences of intense, uninterrupted endurance training in olympic athletes. J Am Coll Cardiol 55:1619-1625
14. Scharhag J, Schneider G, Urhausen A et al (2002) Athlete's heart: right and left ventricular mass and function in male endurance athletes and untrained individuals determined by magnetic resonance imaging. J Am Coll Cardiol 40:1856-1863
15. Pelliccia A, Maron BJ, Di Paolo FM et al (2005) Prevalence and clinical significance of left atrial remodeling in competitive athletes. J Am Coll Cardiol 46:690-696
16. Maron BJ, Pelliccia A, Spirito P (1995) Cardiac disease in young trained athletes. Insights into methods for distinguishing athlete's heart from structural heart disease, with particular emphasis on hypertrophic cardiomyopathy. Circulation 91:1596-15601
17. Pelliccia A, Maron BJ, Spataro A, Proschan MA, Spirito P (1991) The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes. N Engl J Med 324:295-301
18. Pelliccia A, Maron BJ, De Luca R et al (2002) Remodeling of left ventricular hypertrophy in elite athletes after long-term deconditioning. Circulation 105:944-949
19. Libby P (2008) Braunwald's heart disease: a textbook of cardiovascular medicine. Saunders/Elsevier, Philadelphia
20. Katz R, Karliner JS, Resnik R (1978) Effects of a natural volume overload state (pregnancy) on left ventricular performance in normal human subjects. Circulation 58:434-441
21. Schannwell CM, Zimmermann T, Schneppenheim M et al (2002) Left ventricular hypertrophy and diastolic dysfunction in healthy pregnant women. Cardiology 97:73-78
22. Eghbali M, Deva R, Alioua A et al (2005) Molecular and functional signature of heart hypertrophy during pregnancy. Cir Res 96:1208-1216
23. Lemmens K, Doggen K, De Keulenaer GW (2011) Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy. Am J Physiol Heart Circ Physiol 300:H931-H942
24. Andersen JB, Rourke BC, Caiozzo VJ, Bennett AF, Hicks JW (2005) Physiology: postprandial cardiac hypertrophy in pythons. Nature 434:37-38
25. Riquelme CA, Magida JA, Harrison BC et al (2005) Fatty acids identified in the Burmese python promote beneficial cardiac growth. Science 334:528-531
26. Ling LH, Enriquez-Sarano M, Seward JB et al (1966) Clinical outcome of mitral regurgitation due to flail leaflet. N Engl J Med 335:1417-1423
27. Ahmed MI, McGiffin DC, O'Rourke RA, Dell'Italia LJ (2009) Mitral regurgitation. Curr Probl Cardiol 34:93-136
28. Anderson CB, Codd JR, Graff RA et al (1976) Cardiac failure and upper extremity arteriovenous dialysis fistulas. Case reports and a review of the literature. Arch Intern Med 136:292-297
29. Epstein FH, Post RS, McDowell M (1953) The effects of an arteriovenous fistula on renal hemodynamics and electrolyte excretion. J Clin Invest 32:233-241
30. Glaser R, Kramer RJ, Hamby RI, Aintablian A, Zeldis SM (1978) Renal arteriovenous fistula masquerading as severe valvar heart disease. Brit Heart J 40:972-975
31. Peery WH (1987) Clinical spectrum of hereditary hemorrhagic telangiectasia (Osler-Weber- Rendu disease). Am J Med 82:989-997
32. Anand IS, Florea VG (2001) High output cardiac failure. Curr Treat Options Cardiovasc Med 3:151-159
33. Schrier RW (1988) Pathogenesis of sodium and water retention in high-output and low- output cardiac failure, nephrotic syndrome, cirrhosis, and pregnancy (1). N Engl J Med 319:1065-7210
34. Anand IS, Chandrashekhar Y, Ferrari R et al (1992) Pathogenesis of congestive state in chronic obstructive pulmonary disease. Studies of body water and sodium, renal function, hemodynamics, and plasma hormones during edema and after recovery. Circulation 86:12-21
35. Messerli FH, Sundgaard-Riise K, Reisin E et al (1983) Disparate cardiovascular effects of obesity and arterial hypertension. Am J Med 74:808-812
36. Kaltman AJ, Goldring RM (1976) Role of circulatory congestion in the cardiorespiratory failure of obesity. Am J Med 60:645-653
37. Anand IS, Chandrashekhar Y, Wander GS, Chawla LS (1995) Endothelium-derived relaxing factor is important in mediating the high output state in chronic severe anemia. J Am CollCardiol 25:1402-1407
38. Kleaveland JP, Kussmaul WG, Vinciguerra T, Diters R, Carabello BA (1988) Volume overload hypertrophy in a closed-chest model of mitral regurgitation. Am J Physiol 254:H1034-H1041
39. Carabello BA, Nakano K, Corin W, Biederman R, Spann JF Jr (1989) Left ventricular function in experimental volume overload hypertrophy. T Am J Physiol 256:H974-H981
40. Carabello BA, Zile MR, Tanaka R (1992) Cooper Gt. Left ventricular hypertrophy due to volume overload versus pressure overload. Am J Physiol 263:H1137-H1144
41. Neilan TG, Ton-Nu TT, Kawase Y, et al. (2008) Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes. American journal of physiology. Heart Circ Physiol 294:H2106-H2111
42. Pu M, Gao Z, Zhang X, Liao D et al (2009) Impact of mitral regurgitation on left ventricular anatomic and molecular remodeling and systolic function: implication for outcome. Am J Physiol Heart Circ Physiol 296:H1727-H1732
43. Pu M, Gao Z, Li J, Sinoway L, Davidson WR Jr (2005) Development of a new animal model of chronic mitral regurgitation in rats under transesophageal echocardiographic guidance. J Am Soc Echocardiogr y 18:468-474
44. Kim KH, Kim YJ, Ohn JH et al (2012) Long-Term effects of sildenafil in a rat model of chronic mitral regurgitation: benefits of ventricular remodeling and exercise capacity. Circulation 125:1390-1401
45. Liu Z, Hilbelink DR, Crockett WB, Gerdes AM (1991) Regional changes in hemodynamics and cardiac myocyte size in rats with aortocaval fistulas. 1. Developing and established hypertrophy. Circ Res 69:52-58
46. Hammond HK, Roth DA, Insel PA et al (1992) Myocardial beta-adrenergic receptor expression and signal transduction after chronic volume-overload hypertrophy and circulatory congestion. Circulation 85:269-280
47. Modesti PA, Vanni S, Bertolozzi I et al (2004) Different growth factor activation in the right and left ventricles in experimental volume overload. Hypertension 43:101-108
48. Garcia R, Diebold S (1990) Simple, rapid, and effective method of producing aortocaval shunts in the rat. Cardiovasc Res 24:430-432
49. Wang X, Ren B, Liu S et al (2003) Characterization of cardiac hypertrophy and heart failure due to volume overload in the rat. J Appl Physiol 94:752-763
50. Melenovsky V, Skaroupkova P, Benes J et al (2011) The course of heart failure development and mortality in rats with volume overload due to Aorto-Caval Fistula. Kidney Blood Press Res 35:167-173
51. Brower GL, Henegar JR, Janicki JS (1996) Temporal evaluation of left ventricular remodeling and function in rats with chronic volume overload. Am J Physio 271:H2071- H2078
52. Brower GL, Janicki JS (2001) Contribution of ventricular remodeling to pathogenesis of heart. Am J Physiol Heart Circ Physiol 280:H674-H683
53. Souzeau E, Llamas B, Belanger S, Picard S, Deschepper CF (2006) A genetic locus accentuates the effect of volume overload on adverse left ventricular remodeling in male and female rats. Hypertension 47:128-133
54. Oliver-Dussault C, Ascah A, Marcil M et al (2010) Early predictors of cardiac decompensation in experimental volume overload. Mol Cell Biochem 338:271-282
55. Langenickel T, Pagel I, Hohnel K, Dietz R, Willenbrock R (2000) Differential regulation of cardiac ANP and BNP mRNA in different stages of experimental heart failure. Am J Physiol Heart Circ Physiol 278:H1500-H1506
56. Huang M, LeBlanc MH, Hester RL (1994) Evaluation of the needle technique for producing an arteriovenous fistula. J Appl Physio 77:2907-2911
57. Brower GL, Gardner JD, Janicki JS (2003) Gender mediated cardiac protection from adverse ventricular remodeling is abolished by ovariectomy. Mol Cell Biochem 251:89-95
58. Chancey AL, Gardner JD, Murray DB, Brower GL, Janicki JS (2005) Modulation of cardiac mast cell-mediated extracellular matrix degradation by estrogen. Am J Physiol Heart Circ Physiol 289:H316-H321
59. Dent MR, Tappia PS, Dhalla NS (2010) Gender differences in apoptotic signaling in heart failure due to volume overload. Apoptosis 15:499-510
60. Toischer K, Rokita AG, Unsold B et al (2010) Differential cardiac remodeling in preload versus afterload. Circulation 122:993-1003
61. Scheuermann-Freestone M, Freestone NS, Langenickel TH (2001) A new model of congestive heart failure in the mouse due to chronic volume overload. Eur J Heart Fail 3:535-543
62. Magid NM, Young MS, Wallerson DC et al (1988) Hypertrophic and functional response to experimental chronic aortic regurgitation. J Mol Cell Cardiol 20:239-246
63. Magid NM, Borer JS, Young MS, Wallerson DC, DeMonteiro C (1993) Suppression of protein degradation in progressive cardiac hypertrophy of chronic aortic regurgitation. Circulation 87:1249-1257
64. Arsenault M, Plante E, Drolet MC, Couet J (2002) Experimental aortic regurgitation in rats under echocardiographic guidance. J Heart Valve Dis 11:128-134
65. Champetier S, Bojmehrani A, Beaudoin J et al (2009) Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta- adrenergic and renin-angiotensin systems. Am J Physiol Heart Circ Physiol 296:H669- H677
66. Zendaoui A, Lachance D, Roussel E, Couet J, Arsenault M (2011) Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. Circ Heart Fail 4:207-213
67. Lachance D, Plante E, Bouchard-Thomassin AA et al (2009) Moderate exercise training improves survival and ventricular remodeling in an animal model of left ventricular volume overload. Circ Heart Fail 2:437-445
68. Plante E, Gaudreau M, Lachance D et al (2004) Angiotensin-converting enzyme inhibitor captopril prevents volume overload cardiomyopathy in experimental chronic aortic valve regurgitation. Can J Physio Pharmacol 82:191-199
69. Grossman W, Jones D, McLaurin LP (1975) Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest 56:56-64
70. Corin WJ, Monrad ES, Murakami T et al (1987) The relationship of afterload to ejection performance in chronic mitral regurgitation. Circulation 76:59-67
71. Esposito G, Rapacciuolo A, Naga Prasad SV et al (2002) Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress. Circulation 105:85-92
72. Takimoto E, Champion HC, Li M et al (2005) Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med 11:214-222
73. Kupari M, Turto H, Lommi J (2005) Left ventricular hypertrophy in aortic valve stenosis: preventive or promotive of systolic dysfunction and heart failure? Eur Heart J 26:1790-1796
74. Meerson FZ (1961) On the mechanism of compensatory hyperfunction and insufficiency of the heart. Cor et vasa 3:161-177
75. Buyandelger B, Ng KE, Miocic S et al (2011) Genetics of mechanosensation in the heart. J Cardiovasc Transl Res 4:238-244
76. Yamamoto K, Dang QN, Maeda Y et al (2001) Regulation of cardiomyocyte mechanotransduction by the cardiac cycle. Circulation 103:1459-1464
77. Imamura T, McDermott PJ, Kent RL et al. (1994) Acute changes in myosin heavy chain synthesis rate in pressure versus volume overload. Circ Res 75:418-425
78. Matsuo T, Carabello BA, Nagatomo Y et al (1998) Mechanisms of cardiac hypertrophy in canine volume overload. Am J Physiol 275:H65-H74
79. Prochniewicz E, Lowe DA, Spakowicz DJ et al (2008) Functional, structural, and chemical changes in myosin associated with hydrogen peroxide treatment of skeletal muscle fibers. Am J Physiol Cell physio 294:C613-C626
80. Marcus ML, Doty DB, Hiratzka LF, Wright CB, Eastham CL (1982) Decreased coronary reserve: a mechanism for angina pectoris in patients with aortic stenosis and normal coronary arteries. New Eng J Med 307:1362-1366
81. Perrino C, Naga Prasad SV, Mao L et al (2006) Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. J Clin Invest 116:1547-1560
82. Michel JB, Salzmann JL, Ossondo Nlom M et al (1986) Morphometric analysis of collagen network and plasma perfused capillary bed in the myocardium of rats during evolution of cardiac hypertrophy. Basic Res i Cardiol 81:142-154
83. Sano M, Schneider MD (2002) Still stressed out but doing fine: normalization of wall stress is superfluous to maintaining cardiac function in chronic pressure overload. Circulation 105:8-10
84. Carabello BA, Nakano K, Ishihara K et al (1991) Coronary blood flow in dogs with contractile dysfunction due to experimental volume overload. Circulation 83:1063-1075
85. Rakusan K, Moravec J, Hatt PY (1980) Regional capillary supply in the normal and hypertrophied rat heart. Microvasc Res 20:319-326
86. Tsutsui H, Spinale FG, Nagatsu M et al (1994) Effects of chronic beta-adrenergic blockade on the left ventricular and cardiocyte abnormalities of chronic canine mitral regurgitation. J Clin Invest 93:2639-2648
87. Hutchinson KR, Guggilam A, Cismowski MJ, Galantowicz ML, West TA, Stewart JA Jr, Zhang X, Lord KC, Lucchesi PA (2011) Temporal pattern of left ventricular structural and functional remodeling following reversal of volume overload heart failure. J Appl Physiol 111:1778-1788
88. Berko B, Gaasch WH, Tanigawa N, Smith D, Craige E (1987) Disparity between ejection and end- systolic indexes of left ventricular contractility in mitral regurgitation. Circulation 75:1310-1319
89. Ryan TD, Rothstein EC, Aban I et al (2007) Left ventricular eccentric remodeling and matrix loss are mediated by bradykinin and precede ardiomyocyte elongation in rats with volume overload. J Am Coll Cardiol 49:811-821
90. Zile MR, Tomita M, Nakano K et al (1991) Effects of left ventricular volume overload produced by mitral regurgitation on diastolic function. Am J Physiol 261:H1471-H1480
91. Corin WJ, Murakami T, Monrad ES, Hess OM, Krayenbuehl HP (1991) Left ventricular passive diastolic properties in chronic mitral regurgitation. Circulation 83:797-807
92. Urabe Y, Mann DL, Kent RL et al (1992) Cellular and ventricular contractile dysfunction in experimental canine mitral regurgitation. Circ Res 70:131-147
93. Wencker D, Chandra M, Nguyen K et al (2003) A mechanistic role for cardiac myocyte apoptosis in heart failure. J Clin Invest 111:1497-1504
94. Moorjani N, Westaby S, Narula J et al (2009) Effects of left ventricular volume overload on mitochondrial and death-receptor-mediated apoptotic pathways in the transition to heart failure. J Am Coll Cardiol 103:1261-1268
95. Mulieri LA, Leavitt BJ, Martin BJ, Haeberle JR, Alpert NR (1993) Myocardial force- frequency defect in mitral regurgitation heart failure is reversed by forskolin. Circulation 88:2700-2704
96. Leszek P, Szperl M, Klisiewicz AJ et al (2007) Alteration of myocardial sarcoplasmic reticulum Ca2+ -ATPase and Na+ -Ca2+ exchanger expression in human left ventricular volume overload. Eur J Heart Fail 9:579-586
97. Juric D, Yao X, Thandapilly S, Louis X et al (2010) Defects in ryanodine receptor function are associated with systolic dysfunction in rats subjected to volume overload. Experi Physiol 95:869-879
98. Ding YF, Brower GL, Zhong Q et al (2008) Defective intracellular Ca2 + homeostasis contributes to myocyte dysfunction during ventricular remodelling induced by chronic volume overload in rats. Clin Exp Pharmacol Physiol 35:827-835
99. Takewa Y, Chemaly ER, Takaki M et al (2009) Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats. Am J Physiol Heart Circ Physiol 296:H1117-H1124
100. Communal C, Sumandea M, de Tombe P et al (2002) Functional consequences of caspase activation in cardiac myocytes. Proc Natl Acad Sci USA 99:6252-6256
101. Feng J, Schaus BJ, Fallavollita JA, Lee TC, Canty JM Jr et al (2001) Preload induces troponin I degradation independently of myocardial ischemia. Circulation 103:2035-2037
102. Ahmed MI, Gladden JD, Litovsky SH et al (2010) Increased oxidative stress and cardiomyocyte myofibrillar degeneration in patients with chronic isolated mitral regurgitation and ejection fraction >60 %. J Am Coll Cardiol 55:671-679
103. Chen YW, Pat B, Gladden JD et al (2011) Dynamic molecular and histopathological changes in the extracellular matrix and inflammation in the transition to heart failure in isolated volume overload. Am J Physiol Heart Circ Physiol 300:H2251-H2260
104. Hutchinson KR, Stewart JA Jr, Lucchesi PA (2010) Extracellular matrix remodeling during the progression of volume overload-induced heart failure. J Mol Cell Cardiol 48:564-569
105. Zheng J, Chen Y, Pat B et al (2009) Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog. Circulation 119:2086-2095
106. Kim KH, Kim YJ, Lee SP et al (2011) Survival, exercise capacity, and left ventricular remodeling in a rat model of chronic mitral regurgitation: serial echocardiography and pressure-volume analysis. Korean Circ J 41:603-611
107. Gladden JD, Zelickson BR, Wei CC et al (2011) Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload. Free Radic Biol Med 51:1975-1984
108. Ruzicka M, Keeley FW, Leenen FH (1994) The renin-angiotensin system and volume overload- induced changes in cardiac collagen and elastin. Circulation 90:1989-1996
109. Brower GL, Chancey AL, Thanigaraj S, Matsubara BB, Janicki JS (2002) Cause and effect relationship between myocardial mast cell number and matrix metalloproteinase activity. Am J Physiol Heart Circ Physiol 283:H518-H525
110. Levick SP, Melendez GC, Plante E et al (2011) Cardiac mast cells: the centrepiece in adverse myocardial remodelling. Cardiovasc Res 89:12-19
111. Chen Y, Pat B, Zheng J et al (2010) Tumor necrosis factor-alpha produced in cardiomyocytes mediates a predominant myocardial inflammatory response to stretch in early volume overload. J Mol Cell Cardiol 49:70-78
112. Brower GL, Janicki JS (2005) Pharmacologic inhibition of mast cell degranulation prevents left ventricular remodeling induced by chronic volume overload in rats. J Card Fail 11:548-556
113. Levick SP, Gardner JD, Holland M et al (2008) Protection from adverse myocardial remodeling secondary to chronic volume overload in mast cell deficient rats. J Mol Cell Cardiol 45:56-61
114. Stewart JA Jr, Wei CC, Brower GL et al (2003) Cardiac mast cell- and chymase-mediated matrix metalloproteinase activity and left ventricular remodeling in mitral regurgitation in the dog. J Mol Cell Cardiol 35:311-319
115. Oral H, Sivasubramanian N, Dyke DB et al (2003) Myocardial proinflammatory cytokine expression and left ventricular remodeling in patients with chronic mitral regurgitation. Circulation 107:831-837
116. Riegger GA, Liebau G, Bauer E, Kochsiek K (1985) Vasopressin and renin in high output heart ailure of rats: hemodynamic effects of elevated plasma hormone levels. J Cardiovasc Pharmacol 7:1-5
117. Abassi Z, Goltsman I, Karram T, Winaver J, Hoffman A (2011) Aortocaval fistula in rat: a unique model of volume-overload congestive heart failure and cardiac hypertrophy. J Biomed Biotechnol 2011:729497
118. Flaim SF, Minteer WJ (1980) Ventricular volume overload alters cardiac output distribution in rats during exercise. J Appl Physiol 49:482-490
119. Willenbrock R, Pagel I, Scheuermann M et al (1999) Renal function in high-output heart failure in rats: role of endogenous natriuretic peptides. J Am Soc Nephrol 10:572-580
120. Wilkins MR, Settle SL, Stockmann PT, Needleman P (1999) Maximizing the natriuretic effect of endogenous atriopeptin in a rat model of heart failure. Proc Natl Acad Sci USA 87:6465-6469
121. Benes J Jr, Melenovsky V, Skaroupkova P, Pospisilova J, Petrak J, Cervenka L, Sedmera D (2011) Myocardial morphological characteristics and proarrhythmic substrate in the rat model of heart failure due to chronic volume overload. Anat Rec (Hoboken) 294:102-111
122. Dent MR, Das S, Dhalla NS (2007) Alterations in both death and survival signals for apoptosis in heart failure due to volume overload. J Mol Cell Cardiol 43:726-732
123. Liu Z, Hilbelink DR, Gerdes AM (1991) Regional changes in hemodynamics and cardiac myocyte size i n rats with aortocaval fistulas. 2. Long-term effects. Circ Res 69:59-65
124. Petrak J, Pospisilova J, Sedinova M et al (2011) Proteomic and transcriptomic analysis of heart f ailure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets-monoamine oxidase A and transglutaminase 2. Proteome Sci 9:69
125. Melenovsky V, Benes J, Skaroupkova P et al (2011) Metabolic characterization of volume overload heart failure due to aorto-caval fistula in rats. Mol Cell Biochem 354:83-96
126. Stanley WC, Recchia FA, Lopaschuk GD (2005) Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 85:1093-1129
127. Benes J, Kazdova L, Drahota Z, et al. (2011) Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats. Clin Sci (London) 121:29-41
128. Christian B, El Alaoui-Talibi Z, Moravec M, Moravec J (1998) Palmitate oxidation by the mitochondria from volume-overloaded rat hearts. Mol Cell Biochem 180:117-128
129. Razeghi P, Young ME, Alcorn JL et al (2001) Metabolic gene expression in fetal and failing human heart. Circulation 104:2923-2931
130. Pellieux C, Montessuit C, Papageorgiou I, Lerch R (2009) Angiotensin II downregulates the fatty acid oxidation pathway in adult rat cardiomyocytes via release of tumour necrosis factor- alpha. Cardiovas Res 82:341-350
131. van Bilsen M, van Nieuwenhoven FA, van der Vusse GJ (2009) Metabolic remodelling of the failing heart: beneficial or detrimental? Cardiovasc Res 81:420-428
132. Marcil M, Ascah A, Matas J et al (2006) Compensated volume overload increases the vulnerability of heart mitochondria without affecting their functions in the absence of stress. J Mol Cell Cardiol 41:998-1009
133. Nakano K, Swindle MM, Spinale F, Ishihara K, Kanazawa S, Smith A, Biederman RW, Clamp L, Hamada Y, Zile MR et al (1991) Depressed contractile function due to canine mitral regurgitation improves after correction of the volume overload. J Clin Invest 87:2077-2086
134. Oka T, Nishimura H, Ueyama M, Kubota J, Kawamura K (1993) Lisinopril reduces cardiac hypertrophy and mortality in rats with aortocaval fistula. Eur J Pharmacol 234:55-60
135. Spinale FG, Ishihra K, Zile M et al (1993) Structural basis for changes in left ventricular function and geometry because of chronic mitral regurgitation and after correction of volume overload. J thoracic Cardiovasc Surg 106:1147-1157
136. Gerdes AM, Clark LC, Capasso JM (1995) Regression of cardiac hypertrophy after closing an aortocaval fistula in rats. Am J Physiol 268:H2345-H2351
137. Abassi ZA, Brodsky S, Karram T et al (2001) Temporal changes in natriuretic and antinatriuretic systems after closure of a large arteriovenous fistula. Cardiovasc Res 51:567-576
138. Ruzicka M, Yuan B, Leenen FH (1994) Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats. Circulation 90:484-491
139. Perry GJ, Wei CC, Hankes GH et al (2002) Angiotensin II receptor blockade does not improve left ventricular function and remodeling in subacute mitral regurgitation in the dog. J Am Coll Cardiol 39:1374-1379
140. Karram T, Abbasi A, Keidar S et al (2005) Effects of spironolactone and eprosartan on cardiac remodeling and angiotensin-converting enzyme isoforms in rats with experimental heart failure. Am J Physiol Heart Circ Physiol 289:H1351-H1358
141. Francis B, Winaver J, Karram T, Hoffman A, Abassi Z (2004) Renal and systemic effects of chronic blockade of ET(A) or ET(B) receptors in normal rats and animals with experimental heart failure. J Cardiovasc Pharmacol 44(Suppl 1):S54-S58
142. Wei CC, Lucchesi PA, Tallaj J et al (2003) Cardiac interstitial bradykinin and mast cells modulate pattern of LV remodeling in volume overload in rats. Am J Physiol Heart Circ Physiol 285:H784-H792
143. Ulasova E, Gladden JD, Chen Y et al (2011) Loss of interstitial collagen causes structural and functional alterations of cardiomyocyte subsarcolemmal mitochondria in acute volume overload. J Mol Cell Cardiol 50:147-156
144. Sabri A, Rafiq K, Seqqat R, Kolpakov MA, Dillon R, Dell'italia LJ (2008) Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog. Circ Res 102:1127-1136
145. Shyu KG, Lu MJ, Chang H et al (2005) Carvedilol modulates the expression of hypoxia- inducible factor-1 alpha and vascular endothelial growth factor in a rat model of volumeoverload heart failure. J Card Fail 11:152-159
146. Pat B, Killingsworth C, Chen Y et al (2010) Mast cell stabilization decreases cardiomyocyte and LV function in dogs with isolated mitral regurgitation. J Card Fail 16:769-776
147. Pat B, Chen Y, Killingsworth C et al (2010) Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation. Circulation 122:1488-1495
148. Melendez GC, Li J, Law BA et al (2011) Substance P induces adverse myocardial remodelling via a mechanism involving cardiac mast cells. Cardiovasc Res 92:420-429
149. Jobe LJ, Melendez GC, Levick SP, Du Y, Brower GL, Janicki JS (2009) TNF-alpha inhibition attenuates adverse myocardial remodeling in a rat model of volume overload. Am J Physiol Heart Circ Physiol 297:H1462-H1468
150. Abassi ZA, Barac YD, Kostin S et al (2011) TVP1022 attenuates cardiac remodeling and kidney dysfunction in experimental volume overload-induced congestive heart failure. Circ Heart Fail 4:463-473
151. Kawase Y, Ly HQ, Prunier F et al (2008) Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure. J Am Coll Cardiol 51:1112-1119
152. Wegner M, Hirth-Dietrich C, Stasch JP (1996) Role of neutral endopeptidase 24.11 in AV fistular rat model of heart failure. Cardiovas Res 31:891-898
153. Abassi ZA, Yahia A, Zeid S et al (2005) Cardiac and renal effects of omapatrilat, a vasopeptidase inhibitor, in rats with experimental congestive heart failure. Am J Physiol Heart Circ Physiol 288:H722-H728
154. Abassi Z, Burnett JC Jr, Grushka E et al (1991) Atrial natriuretic peptide and renal cGMP in rats with experimental heart failure. Am J Physiol 261:R858-R864
155. Bishara B, Shiekh H, Karram T et al (2008) Effects of novel vasopressin receptor antagonists on renal function and cardiac hypertrophy in rats with experimental congestive heart failure. J Pharmacol Exp Ther 326:414-422
156. Gardner JD, Murray DB, Voloshenyuk TG et al (2010) Estrogen attenuates chronic volume overload induced structural and functional remodeling in male rat hearts. Am J Physiol Heart Circ Physiol 298:H497-H504
157. Goltsman I, Wang X, Lavallie ER et al. (2011) Effects of chronic rosiglitazone treatment on renal. Circ Heart Fail 4:345-354
158. Nemoto S, Razeghi P, Ishiyama M et al (2005) PPAR-gamma agonist rosiglitazone ameliorates ventricular dysfunction in experimental chronic mitral regurgitation. Am J Physiol Heart Circ Physiol 288:H77-H82
159. El Alaoui-Talibi Z, Guendouz A, Moravec M, Moravec J (1997) Control of oxidative metabolism in volume-overloaded rat hearts: effect of propionyl-L-carnitine. Am J Physiol 272:H1615-H1624