-
1
-
-
84877843704
-
Impact of primary elvitegravir resistance-associated mutations in HIV-1 integrase on drug susceptibility and viral replication fitness
-
Abram, M.E., Hluhanich, R.M., Goodman, D.D., Andreatta, K.N., Margot, N.A., Ye, L., Niedziela-Majka, A., Barnes, T.L., Novikov, N., Chen, X., Svarovskaia, E.S., McColl, D.J., White, K.L., Miller, M.D., Impact of primary elvitegravir resistance-associated mutations in HIV-1 integrase on drug susceptibility and viral replication fitness. Antimicrob. Agents Chemother. 57 (2013), 2654–2663.
-
(2013)
Antimicrob. Agents Chemother.
, vol.57
, pp. 2654-2663
-
-
Abram, M.E.1
Hluhanich, R.M.2
Goodman, D.D.3
Andreatta, K.N.4
Margot, N.A.5
Ye, L.6
Niedziela-Majka, A.7
Barnes, T.L.8
Novikov, N.9
Chen, X.10
Svarovskaia, E.S.11
McColl, D.J.12
White, K.L.13
Miller, M.D.14
-
2
-
-
84937540880
-
Dolutegravir versus placebo in subjects harbouring HIV-1 with integrase inhibitor resistance associated substitutions: 48-week results from VIKING-4, a randomized study
-
Akil, B., Blick, G., Hagins, D.P., Ramgopal, M.N., Richmond, G.J., Samuel, R.M., Givens, N., Vavro, C., Song, I.H., Wynne, B., Ait-Khaled, M., Dolutegravir versus placebo in subjects harbouring HIV-1 with integrase inhibitor resistance associated substitutions: 48-week results from VIKING-4, a randomized study. Antivir. Ther. 20 (2015), 343–348.
-
(2015)
Antivir. Ther.
, vol.20
, pp. 343-348
-
-
Akil, B.1
Blick, G.2
Hagins, D.P.3
Ramgopal, M.N.4
Richmond, G.J.5
Samuel, R.M.6
Givens, N.7
Vavro, C.8
Song, I.H.9
Wynne, B.10
Ait-Khaled, M.11
-
3
-
-
84998814996
-
HIV-1 Non Group M Phenotypic Susceptibility to Integrase Inhibitors (Dolutegravir, Elvitegravir and Raltegravir). XXV International HIV Drug Resistance Workshop February 20–21, 2016
-
ABSTRACT 50 Boston, MA, USA
-
Alessandri-Gradt, E., Collin, G., et al. HIV-1 Non Group M Phenotypic Susceptibility to Integrase Inhibitors (Dolutegravir, Elvitegravir and Raltegravir). XXV International HIV Drug Resistance Workshop February 20–21, 2016. 2016, ABSTRACT 50, Boston, MA, USA.
-
(2016)
-
-
Alessandri-Gradt, E.1
Collin, G.2
-
4
-
-
77958168446
-
Characterization of integrase region polymorphisms in HIV type 1 CRF06_cpx viruses in treatment-naive patients in Estonia
-
Avi, R., Huik, K., Sadam, M., Karki, T., Krispin, T., Ainsalu, K., Paap, P., Schmidt, J., Nikitina, N., Lutsar, I., Characterization of integrase region polymorphisms in HIV type 1 CRF06_cpx viruses in treatment-naive patients in Estonia. AIDS Res. Hum. Retrovir. 26 (2010), 1109–1113.
-
(2010)
AIDS Res. Hum. Retrovir.
, vol.26
, pp. 1109-1113
-
-
Avi, R.1
Huik, K.2
Sadam, M.3
Karki, T.4
Krispin, T.5
Ainsalu, K.6
Paap, P.7
Schmidt, J.8
Nikitina, N.9
Lutsar, I.10
-
5
-
-
77956228894
-
HIV-1 subtype B and C integrase enzymes exhibit differential patterns of resistance to integrase inhibitors in biochemical assays
-
Bar-Magen, T., Donahue, D.A., McDonough, E.I., Kuhl, B.D., Faltenbacher, V.H., Xu, H., Michaud, V., Sloan, R.D., Wainberg, M.A., HIV-1 subtype B and C integrase enzymes exhibit differential patterns of resistance to integrase inhibitors in biochemical assays. AIDS 24 (2010), 2171–2179.
-
(2010)
AIDS
, vol.24
, pp. 2171-2179
-
-
Bar-Magen, T.1
Donahue, D.A.2
McDonough, E.I.3
Kuhl, B.D.4
Faltenbacher, V.H.5
Xu, H.6
Michaud, V.7
Sloan, R.D.8
Wainberg, M.A.9
-
6
-
-
84875082394
-
Genetic analysis of HIV-1 integrase sequences from treatment naive individuals in northeastern South Africa
-
Bessong, P.O., Nwobegahay, J., Genetic analysis of HIV-1 integrase sequences from treatment naive individuals in northeastern South Africa. Int. J. Mol. Sci. 14 (2013), 5013–5024.
-
(2013)
Int. J. Mol. Sci.
, vol.14
, pp. 5013-5024
-
-
Bessong, P.O.1
Nwobegahay, J.2
-
7
-
-
79953189667
-
Transmitted raltegravir resistance in an HIV-1 CRF_AG-infected patient
-
Boyd, S.D., Maldarelli, F., Sereti, I., Ouedraogo, G.L., Rehm, C.A., Boltz, V., Shoemaker, D., Pau, A.K., Transmitted raltegravir resistance in an HIV-1 CRF_AG-infected patient. Antivir. Ther. 16 (2011), 257–261.
-
(2011)
Antivir. Ther.
, vol.16
, pp. 257-261
-
-
Boyd, S.D.1
Maldarelli, F.2
Sereti, I.3
Ouedraogo, G.L.4
Rehm, C.A.5
Boltz, V.6
Shoemaker, D.7
Pau, A.K.8
-
8
-
-
79952711748
-
Subtype diversity associated with the development of HIV-1 resistance to integrase inhibitors
-
Brenner, B.G., Lowe, M., Moisi, D., Hardy, I., Gagnon, S., Charest, H., Baril, J.G., Wainberg, M.A., Roger, M., Subtype diversity associated with the development of HIV-1 resistance to integrase inhibitors. J. Med. Virol. 83 (2011), 751–759.
-
(2011)
J. Med. Virol.
, vol.83
, pp. 751-759
-
-
Brenner, B.G.1
Lowe, M.2
Moisi, D.3
Hardy, I.4
Gagnon, S.5
Charest, H.6
Baril, J.G.7
Wainberg, M.A.8
Roger, M.9
-
9
-
-
34648824673
-
Human immunodeficiency virus type 1 subtype distribution in the worldwide epidemic: pathogenetic and therapeutic implications
-
Buonaguro, L., Tornesello, M.L., Buonaguro, F.M., Human immunodeficiency virus type 1 subtype distribution in the worldwide epidemic: pathogenetic and therapeutic implications. J. Virol. 81 (2007), 10209–10219.
-
(2007)
J. Virol.
, vol.81
, pp. 10209-10219
-
-
Buonaguro, L.1
Tornesello, M.L.2
Buonaguro, F.M.3
-
10
-
-
84882912698
-
Dolutegravir versus raltegravir in antiretroviral-experienced, integrase-inhibitor-naive adults with HIV: week 48 results from the randomised, double-blind, non-inferiority SAILING study
-
Cahn, P., Pozniak, A.L., Mingrone, H., Shuldyakov, A., Brites, C., Andrade-Villanueva, J.F., Richmond, G., Buendia, C.B., Fourie, J., Ramgopal, M., Hagins, D., Felizarta, F., Madruga, J., Reuter, T., Newman, T., Small, C.B., Lombaard, J., Grinsztejn, B., Dorey, D., Underwood, M., Griffith, S., Min, S., Dolutegravir versus raltegravir in antiretroviral-experienced, integrase-inhibitor-naive adults with HIV: week 48 results from the randomised, double-blind, non-inferiority SAILING study. Lancet 382 (2013), 700–708.
-
(2013)
Lancet
, vol.382
, pp. 700-708
-
-
Cahn, P.1
Pozniak, A.L.2
Mingrone, H.3
Shuldyakov, A.4
Brites, C.5
Andrade-Villanueva, J.F.6
Richmond, G.7
Buendia, C.B.8
Fourie, J.9
Ramgopal, M.10
Hagins, D.11
Felizarta, F.12
Madruga, J.13
Reuter, T.14
Newman, T.15
Small, C.B.16
Lombaard, J.17
Grinsztejn, B.18
Dorey, D.19
Underwood, M.20
Griffith, S.21
Min, S.22
more..
-
11
-
-
80155188567
-
Cross-resistance profile of the novel integrase inhibitor dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravir
-
Canducci, F., Ceresola, E.R., Boeri, E., Spagnuolo, V., Cossarini, F., Castagna, A., Lazzarin, A., Clementi, M., Cross-resistance profile of the novel integrase inhibitor dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravir. J. Infect. Dis. 204 (2011), 1811–1815.
-
(2011)
J. Infect. Dis.
, vol.204
, pp. 1811-1815
-
-
Canducci, F.1
Ceresola, E.R.2
Boeri, E.3
Spagnuolo, V.4
Cossarini, F.5
Castagna, A.6
Lazzarin, A.7
Clementi, M.8
-
12
-
-
84898987717
-
Dolutegravir in antiretroviral-experienced patients with raltegravir- and/or elvitegravir-resistant HIV-1: 24-week results of the phase III VIKING-3 study
-
Castagna, A., Maggiolo, F., Penco, G., Wright, D., Mills, A., Grossberg, R., Molina, J.M., Chas, J., Durant, J., Moreno, S., Doroana, M., Ait-Khaled, M., Huang, J., Min, S., Song, I., Vavro, C., Nichols, G., Yeo, J.M., Dolutegravir in antiretroviral-experienced patients with raltegravir- and/or elvitegravir-resistant HIV-1: 24-week results of the phase III VIKING-3 study. J. Infect. Dis. 210 (2014), 354–362.
-
(2014)
J. Infect. Dis.
, vol.210
, pp. 354-362
-
-
Castagna, A.1
Maggiolo, F.2
Penco, G.3
Wright, D.4
Mills, A.5
Grossberg, R.6
Molina, J.M.7
Chas, J.8
Durant, J.9
Moreno, S.10
Doroana, M.11
Ait-Khaled, M.12
Huang, J.13
Min, S.14
Song, I.15
Vavro, C.16
Nichols, G.17
Yeo, J.M.18
-
13
-
-
77956109186
-
Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors
-
Ceccherini-Silberstein, F., Van Baelen, K., Armenia, D., Trignetti, M., Rondelez, E., Fabeni, L., Scopelliti, F., Pollicita, M., Van Wesenbeeck, L., Van Eygen, V., Dori, L., Sarmati, L., Aquaro, S., Palamara, G., Andreoni, M., Stuyver, L.J., Perno, C.F., Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors. Antimicrob. Agents Chemother. 54 (2010), 3938–3948.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 3938-3948
-
-
Ceccherini-Silberstein, F.1
Van Baelen, K.2
Armenia, D.3
Trignetti, M.4
Rondelez, E.5
Fabeni, L.6
Scopelliti, F.7
Pollicita, M.8
Van Wesenbeeck, L.9
Van Eygen, V.10
Dori, L.11
Sarmati, L.12
Aquaro, S.13
Palamara, G.14
Andreoni, M.15
Stuyver, L.J.16
Perno, C.F.17
-
14
-
-
78349311194
-
In-vitro phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitor S/GSK1349572
-
Charpentier, C., Larrouy, L., Collin, G., Damond, F., Matheron, S., Chene, G., Nie, T., Schinazi, R., Brun-Vezinet, F., Descamps, D., In-vitro phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitor S/GSK1349572. AIDS 24 (2010), 2753–2755.
-
(2010)
AIDS
, vol.24
, pp. 2753-2755
-
-
Charpentier, C.1
Larrouy, L.2
Collin, G.3
Damond, F.4
Matheron, S.5
Chene, G.6
Nie, T.7
Schinazi, R.8
Brun-Vezinet, F.9
Descamps, D.10
-
15
-
-
78751618860
-
Integrase and fusion inhibitors transmitted drug resistance in naive patients with recent diagnosis of HIV-1 infection
-
Cossarini, F., Boeri, E., Canducci, F., Salpietro, S., Bigoloni, A., Galli, L., Spagnuolo, V., Castagna, A., Clementi, M., Lazzarin, A., Gianotti, N., Integrase and fusion inhibitors transmitted drug resistance in naive patients with recent diagnosis of HIV-1 infection. J. Acquir. Immune Defic. Syndr. 56 (2011), e51–e54.
-
(2011)
J. Acquir. Immune Defic. Syndr.
, vol.56
, pp. e51-e54
-
-
Cossarini, F.1
Boeri, E.2
Canducci, F.3
Salpietro, S.4
Bigoloni, A.5
Galli, L.6
Spagnuolo, V.7
Castagna, A.8
Clementi, M.9
Lazzarin, A.10
Gianotti, N.11
-
16
-
-
84865758396
-
Raltegravir-based regimens are effective in HIV-1 group O-infected patients
-
Depatureaux, A., Leoz, M., Le Moal, G., Pathe, J.P., Pavie, J., Batisse, D., Daneluzzi, V., Genet, P., Gerard, L., Lascaux-Cametz, A.S., Lambolez, T., Chennebault, J.M., Plantier, J.C., Raltegravir-based regimens are effective in HIV-1 group O-infected patients. J. Acquir. Immune Defic. Syndr. 61 (2012), e1–e3.
-
(2012)
J. Acquir. Immune Defic. Syndr.
, vol.61
, pp. e1-e3
-
-
Depatureaux, A.1
Leoz, M.2
Le Moal, G.3
Pathe, J.P.4
Pavie, J.5
Batisse, D.6
Daneluzzi, V.7
Genet, P.8
Gerard, L.9
Lascaux-Cametz, A.S.10
Lambolez, T.11
Chennebault, J.M.12
Plantier, J.C.13
-
17
-
-
84976465588
-
HIV-1 group O integrase displays lower susceptibility to raltegravir and has a different mutational pathway for resistance than HIV-1 group M
-
Depatureaux, A., Mesplede, T., Quashie, P., Oliveira, M., Moisi, D., Brenner, B., Wainberg, M., HIV-1 group O integrase displays lower susceptibility to raltegravir and has a different mutational pathway for resistance than HIV-1 group M. J. Int. AIDS Soc., 17, 2014, 19738.
-
(2014)
J. Int. AIDS Soc.
, vol.17
, pp. 19738
-
-
Depatureaux, A.1
Mesplede, T.2
Quashie, P.3
Oliveira, M.4
Moisi, D.5
Brenner, B.6
Wainberg, M.7
-
18
-
-
84939781115
-
HIV-1 group O resistance against integrase inhibitors
-
Depatureaux, A., Mesplede, T., Quashie, P., Oliveira, M., Moisi, D., Plantier, J.C., Brenner, B., Wainberg, M.A., HIV-1 group O resistance against integrase inhibitors. J. Acquir. Immune Defic. Syndr. 70 (2015), 9–15.
-
(2015)
J. Acquir. Immune Defic. Syndr.
, vol.70
, pp. 9-15
-
-
Depatureaux, A.1
Mesplede, T.2
Quashie, P.3
Oliveira, M.4
Moisi, D.5
Plantier, J.C.6
Brenner, B.7
Wainberg, M.A.8
-
19
-
-
84873633830
-
Safety and efficacy of dolutegravir in treatment-experienced subjects with raltegravir-resistant HIV type 1 infection: 24-week results of the VIKING study
-
Eron, J.J., Clotet, B., Durant, J., Katlama, C., Kumar, P., Lazzarin, A., Poizot-Martin, I., Richmond, G., Soriano, V., Ait-Khaled, M., Fujiwara, T., Huang, J., Min, S., Vavro, C., Yeo, J., Safety and efficacy of dolutegravir in treatment-experienced subjects with raltegravir-resistant HIV type 1 infection: 24-week results of the VIKING study. J. Infect. Dis. 207 (2013), 740–748.
-
(2013)
J. Infect. Dis.
, vol.207
, pp. 740-748
-
-
Eron, J.J.1
Clotet, B.2
Durant, J.3
Katlama, C.4
Kumar, P.5
Lazzarin, A.6
Poizot-Martin, I.7
Richmond, G.8
Soriano, V.9
Ait-Khaled, M.10
Fujiwara, T.11
Huang, J.12
Min, S.13
Vavro, C.14
Yeo, J.15
-
20
-
-
84929755856
-
Cross-resistance to elvitegravir and dolutegravir in 502 patients failing on raltegravir: a French national study of raltegravir-experienced HIV-1-infected patients
-
Fourati, S., Charpentier, C., Amiel, C., Morand-Joubert, L., Reigadas, S., Trabaud, M.A., Delaugerre, C., Nicot, F., Rodallec, A., Maillard, A., Mirand, A., Jeulin, H., Montes, B., Barin, F., Bettinger, D., Le Guillou-Guillemette, H., Vallet, S., Signori-Schmuck, A., Descamps, D., Calvez, V., Flandre, P., Marcelin, A.G., Cross-resistance to elvitegravir and dolutegravir in 502 patients failing on raltegravir: a French national study of raltegravir-experienced HIV-1-infected patients. J. Antimicrob. Chemother. 70 (2015), 1507–1512.
-
(2015)
J. Antimicrob. Chemother.
, vol.70
, pp. 1507-1512
-
-
Fourati, S.1
Charpentier, C.2
Amiel, C.3
Morand-Joubert, L.4
Reigadas, S.5
Trabaud, M.A.6
Delaugerre, C.7
Nicot, F.8
Rodallec, A.9
Maillard, A.10
Mirand, A.11
Jeulin, H.12
Montes, B.13
Barin, F.14
Bettinger, D.15
Le Guillou-Guillemette, H.16
Vallet, S.17
Signori-Schmuck, A.18
Descamps, D.19
Calvez, V.20
Flandre, P.21
Marcelin, A.G.22
more..
-
21
-
-
79953882562
-
Resistance associated mutations to dolutegravir (S/GSK1349572) in HIV-infected patients–impact of HIV subtypes and prior raltegravir experience
-
Garrido, C., Soriano, V., Geretti, A.M., Zahonero, N., Garcia, S., Booth, C., Gutierrez, F., Viciana, I., de Mendoza, C., Resistance associated mutations to dolutegravir (S/GSK1349572) in HIV-infected patients–impact of HIV subtypes and prior raltegravir experience. Antivir. Res. 90 (2011), 164–167.
-
(2011)
Antivir. Res.
, vol.90
, pp. 164-167
-
-
Garrido, C.1
Soriano, V.2
Geretti, A.M.3
Zahonero, N.4
Garcia, S.5
Booth, C.6
Gutierrez, F.7
Viciana, I.8
de Mendoza, C.9
-
22
-
-
84870060790
-
Emerging patterns and implications of HIV-1 integrase inhibitor resistance
-
Geretti, A.M., Armenia, D., Ceccherini-Silberstein, F., Emerging patterns and implications of HIV-1 integrase inhibitor resistance. Curr. Opin. Infect. Dis. 25 (2012), 677–686.
-
(2012)
Curr. Opin. Infect. Dis.
, vol.25
, pp. 677-686
-
-
Geretti, A.M.1
Armenia, D.2
Ceccherini-Silberstein, F.3
-
23
-
-
84907358049
-
Resistance to HIV integrase strand transfer inhibitors: in vitro findings and clinical consequences
-
Grobler, J.A., Hazuda, D.J., Resistance to HIV integrase strand transfer inhibitors: in vitro findings and clinical consequences. Curr. Opin. Virol. 8c (2014), 98–103.
-
(2014)
Curr. Opin. Virol.
, vol.8c
, pp. 98-103
-
-
Grobler, J.A.1
Hazuda, D.J.2
-
24
-
-
80052847754
-
Dolutegravir (S/GSK1349572) exhibits significantly slower dissociation than raltegravir and elvitegravir from wild-type and integrase inhibitor-resistant HIV-1 integrase-DNA complexes
-
Hightower, K.E., Wang, R., Deanda, F., Johns, B.A., Weaver, K., Shen, Y., Tomberlin, G.H., Carter, H.L. 3rd, Broderick, T., Sigethy, S., Seki, T., Kobayashi, M., Underwood, M.R., Dolutegravir (S/GSK1349572) exhibits significantly slower dissociation than raltegravir and elvitegravir from wild-type and integrase inhibitor-resistant HIV-1 integrase-DNA complexes. Antimicrob. Agents Chemother. 55 (2011), 4552–4559.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 4552-4559
-
-
Hightower, K.E.1
Wang, R.2
Deanda, F.3
Johns, B.A.4
Weaver, K.5
Shen, Y.6
Tomberlin, G.H.7
Carter, H.L.8
Broderick, T.9
Sigethy, S.10
Seki, T.11
Kobayashi, M.12
Underwood, M.R.13
-
25
-
-
79953200796
-
Transmitted resistance to HIV integrase strand-transfer inhibitors: right on schedule
-
Hurt, C.B., Transmitted resistance to HIV integrase strand-transfer inhibitors: right on schedule. Antivir. Ther. 16 (2011), 137–140.
-
(2011)
Antivir. Ther.
, vol.16
, pp. 137-140
-
-
Hurt, C.B.1
-
26
-
-
84892766007
-
Resistance to HIV integrase strand transfer inhibitors among clinical specimens in the United States, 2009-2012
-
Hurt, C.B., Sebastian, J., Hicks, C.B., Eron, J.J., Resistance to HIV integrase strand transfer inhibitors among clinical specimens in the United States, 2009-2012. Clin. Infect. Dis. 58 (2014), 423–431.
-
(2014)
Clin. Infect. Dis.
, vol.58
, pp. 423-431
-
-
Hurt, C.B.1
Sebastian, J.2
Hicks, C.B.3
Eron, J.J.4
-
27
-
-
78751697293
-
In vitro antiretroviral properties of S/GSK1349572, a next-generation HIV integrase inhibitor
-
Kobayashi, M., Yoshinaga, T., Seki, T., Wakasa-Morimoto, C., Brown, K.W., Ferris, R., Foster, S.A., Hazen, R.J., Miki, S., Suyama-Kagitani, A., Kawauchi-Miki, S., Taishi, T., Kawasuji, T., Johns, B.A., Underwood, M.R., Garvey, E.P., Sato, A., Fujiwara, T., In vitro antiretroviral properties of S/GSK1349572, a next-generation HIV integrase inhibitor. Antimicrob. Agents Chemother. 55 (2011), 813–821.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 813-821
-
-
Kobayashi, M.1
Yoshinaga, T.2
Seki, T.3
Wakasa-Morimoto, C.4
Brown, K.W.5
Ferris, R.6
Foster, S.A.7
Hazen, R.J.8
Miki, S.9
Suyama-Kagitani, A.10
Kawauchi-Miki, S.11
Taishi, T.12
Kawasuji, T.13
Johns, B.A.14
Underwood, M.R.15
Garvey, E.P.16
Sato, A.17
Fujiwara, T.18
-
28
-
-
34447263572
-
Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance
-
Lataillade, M., Chiarella, J., Kozal, M.J., Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance. Antivir. Ther. 12 (2007), 563–570.
-
(2007)
Antivir. Ther.
, vol.12
, pp. 563-570
-
-
Lataillade, M.1
Chiarella, J.2
Kozal, M.J.3
-
29
-
-
84959904913
-
Deep analysis of HIV-1 natural variability across HIV-1 variants at residues associated with integrase inhibitor (INI) resistance in INI-naive individuals
-
Llacer Delicado, T., Torrecilla, E., Holguin, A., Deep analysis of HIV-1 natural variability across HIV-1 variants at residues associated with integrase inhibitor (INI) resistance in INI-naive individuals. J. Antimicrob. Chemother. 71 (2016), 362–366.
-
(2016)
J. Antimicrob. Chemother.
, vol.71
, pp. 362-366
-
-
Llacer Delicado, T.1
Torrecilla, E.2
Holguin, A.3
-
30
-
-
58549116531
-
Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: genetic and structural in silico analyses
-
Loizidou, E.Z., Kousiappa, I., Zeinalipour-Yazdi, C.D., Van de Vijver, D.A., Kostrikis, L.G., Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: genetic and structural in silico analyses. Biochemistry 48 (2009), 4–6.
-
(2009)
Biochemistry
, vol.48
, pp. 4-6
-
-
Loizidou, E.Z.1
Kousiappa, I.2
Zeinalipour-Yazdi, C.D.3
Van de Vijver, D.A.4
Kostrikis, L.G.5
-
31
-
-
61849176462
-
Genetic barriers for integrase inhibitor drug resistance in HIV type-1 B and CRF02_AG subtypes
-
Maiga, A.I., Malet, I., Soulie, C., Derache, A., Koita, V., Amellal, B., Tchertanov, L., Delelis, O., Morand-Joubert, L., Mouscadet, J.F., Murphy, R., Cisse, M., Katlama, C., Calvez, V., Marcelin, A.G., Genetic barriers for integrase inhibitor drug resistance in HIV type-1 B and CRF02_AG subtypes. Antivir. Ther. 14 (2009), 123–129.
-
(2009)
Antivir. Ther.
, vol.14
, pp. 123-129
-
-
Maiga, A.I.1
Malet, I.2
Soulie, C.3
Derache, A.4
Koita, V.5
Amellal, B.6
Tchertanov, L.7
Delelis, O.8
Morand-Joubert, L.9
Mouscadet, J.F.10
Murphy, R.11
Cisse, M.12
Katlama, C.13
Calvez, V.14
Marcelin, A.G.15
-
32
-
-
41849083439
-
Structural effects of amino acid variations between B and CRF02-AG HIV-1 integrases
-
Malet, I., Soulie, C., Tchertanov, L., Derache, A., Amellal, B., Traore, O., Simon, A., Katlama, C., Mouscadet, J.F., Calvez, V., Marcelin, A.G., Structural effects of amino acid variations between B and CRF02-AG HIV-1 integrases. J. Med. Virol. 80 (2008), 754–761.
-
(2008)
J. Med. Virol.
, vol.80
, pp. 754-761
-
-
Malet, I.1
Soulie, C.2
Tchertanov, L.3
Derache, A.4
Amellal, B.5
Traore, O.6
Simon, A.7
Katlama, C.8
Mouscadet, J.F.9
Calvez, V.10
Marcelin, A.G.11
-
33
-
-
81855199761
-
The HIV-1 integrase G118R mutation confers raltegravir resistance to the CRF02_AG HIV-1 subtype
-
Malet, I., Fourati, S., Charpentier, C., Morand-Joubert, L., Armenia, D., Wirden, M., Sayon, S., Van Houtte, M., Ceccherini-Silberstein, F., Brun-Vezinet, F., Perno, C.F., Descamps, D., Capt, A., Calvez, V., Marcelin, A.G., The HIV-1 integrase G118R mutation confers raltegravir resistance to the CRF02_AG HIV-1 subtype. J. Antimicrob. Chemother. 66 (2011), 2827–2830.
-
(2011)
J. Antimicrob. Chemother.
, vol.66
, pp. 2827-2830
-
-
Malet, I.1
Fourati, S.2
Charpentier, C.3
Morand-Joubert, L.4
Armenia, D.5
Wirden, M.6
Sayon, S.7
Van Houtte, M.8
Ceccherini-Silberstein, F.9
Brun-Vezinet, F.10
Perno, C.F.11
Descamps, D.12
Capt, A.13
Calvez, V.14
Marcelin, A.G.15
-
34
-
-
84907429695
-
Is resistance to dolutegravir possible when this drug is used in first-line therapy?
-
Mesplede, T., Wainberg, M.A., Is resistance to dolutegravir possible when this drug is used in first-line therapy?. Viruses 6 (2014), 3377–3385.
-
(2014)
Viruses
, vol.6
, pp. 3377-3385
-
-
Mesplede, T.1
Wainberg, M.A.2
-
35
-
-
84865634229
-
Resistance to HIV integrase inhibitors
-
Mesplede, T., Quashie, P.K., Wainberg, M.A., Resistance to HIV integrase inhibitors. Curr. Opin. HIV AIDS 7 (2012), 401–408.
-
(2012)
Curr. Opin. HIV AIDS
, vol.7
, pp. 401-408
-
-
Mesplede, T.1
Quashie, P.K.2
Wainberg, M.A.3
-
36
-
-
84874039772
-
Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure
-
Mesplede, T., Quashie, P.K., Osman, N., Han, Y., Singhroy, D.N., Lie, Y., Petropoulos, C.J., Huang, W., Wainberg, M.A., Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure. Retrovirology, 10, 2013, 22.
-
(2013)
Retrovirology
, vol.10
, pp. 22
-
-
Mesplede, T.1
Quashie, P.K.2
Osman, N.3
Han, Y.4
Singhroy, D.N.5
Lie, Y.6
Petropoulos, C.J.7
Huang, W.8
Wainberg, M.A.9
-
37
-
-
84998743026
-
In Vitro Selection of HIV-1 Subtype C Resistant to Integrase Strand Transfer Inhibitors. XXV International HIV Drug Resistance Workshop February 20–21, 2016
-
(Boston)
-
Mphahlele, M., Giacobbi, N., Hewer, R., Travers, S.A.A., Mosebi, S., Steegen, K., Venter, F., Carmona, S., Stevens, W.S., Sluis-Cremer, N., Papathanasopoulos, M.A., In Vitro Selection of HIV-1 Subtype C Resistant to Integrase Strand Transfer Inhibitors. XXV International HIV Drug Resistance Workshop February 20–21, 2016. 7, 2016 (Boston).
-
(2016)
, vol.7
-
-
Mphahlele, M.1
Giacobbi, N.2
Hewer, R.3
Travers, S.A.A.4
Mosebi, S.5
Steegen, K.6
Venter, F.7
Carmona, S.8
Stevens, W.S.9
Sluis-Cremer, N.10
Papathanasopoulos, M.A.11
-
38
-
-
84948973600
-
Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates
-
Mulu, A., Maier, M., Liebert, U.G., Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates. J. Transl. Med., 13, 2015, 377.
-
(2015)
J. Transl. Med.
, vol.13
, pp. 377
-
-
Mulu, A.1
Maier, M.2
Liebert, U.G.3
-
39
-
-
50949099460
-
Analysis of natural sequence variation and covariation in human immunodeficiency virus type 1 integrase
-
Myers, R.E., Pillay, D., Analysis of natural sequence variation and covariation in human immunodeficiency virus type 1 integrase. J. Virol. 82 (2008), 9228–9235.
-
(2008)
J. Virol.
, vol.82
, pp. 9228-9235
-
-
Myers, R.E.1
Pillay, D.2
-
40
-
-
84861199642
-
Genetic barrier to the development of resistance to integrase inhibitors in HIV-1 subtypes CRF01_AE and B
-
Nguyen, H.L., Ruxrungtham, K., Delaugerre, C., Genetic barrier to the development of resistance to integrase inhibitors in HIV-1 subtypes CRF01_AE and B. Intervirology 55 (2012), 287–295.
-
(2012)
Intervirology
, vol.55
, pp. 287-295
-
-
Nguyen, H.L.1
Ruxrungtham, K.2
Delaugerre, C.3
-
41
-
-
78650190619
-
Natural polymorphisms of HIV-1 CRF01_AE integrase coding region in ARV-naive individuals in Cambodia, Thailand and Vietnam: an ANRS AC12 working group study
-
Nouhin, J., Donchai, T., Hoang, K.T., Ken, S., Kamkorn, J., Tran, T., Ayouba, A., Peeters, M., Chaix, M.L., Lien, T.X., Nerrienet, E., Ngo-Giang-Huong, N., Natural polymorphisms of HIV-1 CRF01_AE integrase coding region in ARV-naive individuals in Cambodia, Thailand and Vietnam: an ANRS AC12 working group study. Infect. Genet. Evol. 11 (2011), 38–43.
-
(2011)
Infect. Genet. Evol.
, vol.11
, pp. 38-43
-
-
Nouhin, J.1
Donchai, T.2
Hoang, K.T.3
Ken, S.4
Kamkorn, J.5
Tran, T.6
Ayouba, A.7
Peeters, M.8
Chaix, M.L.9
Lien, T.X.10
Nerrienet, E.11
Ngo-Giang-Huong, N.12
-
42
-
-
84943792977
-
Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout
-
Osman, N., Mesplede, T., Quashie, P.K., Oliveira, M., Zanichelli, V., Wainberg, M.A., Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout. J. Antimicrob. Chemother. 70 (2015), 2810–2815.
-
(2015)
J. Antimicrob. Chemother.
, vol.70
, pp. 2810-2815
-
-
Osman, N.1
Mesplede, T.2
Quashie, P.K.3
Oliveira, M.4
Zanichelli, V.5
Wainberg, M.A.6
-
43
-
-
84941744457
-
Review of integrase strand transfer inhibitors for the treatment of human immunodeficiency virus infection
-
Park, T.E., Mohamed, A., Kalabalik, J., Sharma, R., Review of integrase strand transfer inhibitors for the treatment of human immunodeficiency virus infection. Expert Rev. Anti-Infect. Ther. 13 (2015), 1195–1212.
-
(2015)
Expert Rev. Anti-Infect. Ther.
, vol.13
, pp. 1195-1212
-
-
Park, T.E.1
Mohamed, A.2
Kalabalik, J.3
Sharma, R.4
-
44
-
-
67651165520
-
Lack of primary mutations associated with integrase inhibitors among HIV-1 subtypes B, C, and F circulating in Brazil
-
Passaes, C.B., Guimaraes, M.L., Fernandez, S.L., Lorete Rdos, S., Teixeira, S.L., Fernandez, J.C., Morgado, M.G., Lack of primary mutations associated with integrase inhibitors among HIV-1 subtypes B, C, and F circulating in Brazil. J. Acquir. Immune Defic. Syndr. 51 (2009), 7–12.
-
(2009)
J. Acquir. Immune Defic. Syndr.
, vol.51
, pp. 7-12
-
-
Passaes, C.B.1
Guimaraes, M.L.2
Fernandez, S.L.3
Lorete Rdos, S.4
Teixeira, S.L.5
Fernandez, J.C.6
Morgado, M.G.7
-
45
-
-
84864197719
-
HIV type 1 integrase polymorphisms in treatment-naive and treatment-experienced HIV type 1-infected patients in Thailand where HIV type 1 subtype A/E predominates
-
Phuphuakrat, A., Pasomsub, E., Kiertiburanakul, S., Chantratita, W., Sungkanuparph, S., HIV type 1 integrase polymorphisms in treatment-naive and treatment-experienced HIV type 1-infected patients in Thailand where HIV type 1 subtype A/E predominates. AIDS Res. Hum. Retrovir. 28 (2012), 937–943.
-
(2012)
AIDS Res. Hum. Retrovir.
, vol.28
, pp. 937-943
-
-
Phuphuakrat, A.1
Pasomsub, E.2
Kiertiburanakul, S.3
Chantratita, W.4
Sungkanuparph, S.5
-
46
-
-
84871781846
-
Evolution of HIV integrase resistance mutations
-
Quashie, P.K., Mesplede, T., Wainberg, M.A., Evolution of HIV integrase resistance mutations. Curr. Opin. Infect. Dis. 26 (2013), 43–49.
-
(2013)
Curr. Opin. Infect. Dis.
, vol.26
, pp. 43-49
-
-
Quashie, P.K.1
Mesplede, T.2
Wainberg, M.A.3
-
47
-
-
84923206490
-
Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase
-
Quashie, P.K., Oliviera, M., Veres, T., Osman, N., Han, Y.S., Hassounah, S., Lie, Y., Huang, W., Mesplede, T., Wainberg, M.A., Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase. J. Virol. 89 (2015), 3163–3175.
-
(2015)
J. Virol.
, vol.89
, pp. 3163-3175
-
-
Quashie, P.K.1
Oliviera, M.2
Veres, T.3
Osman, N.4
Han, Y.S.5
Hassounah, S.6
Lie, Y.7
Huang, W.8
Mesplede, T.9
Wainberg, M.A.10
-
48
-
-
84888400011
-
HIV-1 genetic variability and clinical implications
-
Santoro, M.M., Perno, C.F., HIV-1 genetic variability and clinical implications. ISRN Microbiol., 2013, 2013, 481314.
-
(2013)
ISRN Microbiol.
, vol.2013
, pp. 481314
-
-
Santoro, M.M.1
Perno, C.F.2
-
49
-
-
83055179796
-
The SnoB study: frequency of baseline raltegravir resistance mutations prevalence in different non-B subtypes
-
Sierra, S., Lubke, N., Walter, H., Schulter, E., Reuter, S., Fatkenheuer, G., Bickel, M., da Silva, H., Kaiser, R., Esser, S., The SnoB study: frequency of baseline raltegravir resistance mutations prevalence in different non-B subtypes. Med. Microbiol. Immunol. 200 (2011), 225–232.
-
(2011)
Med. Microbiol. Immunol.
, vol.200
, pp. 225-232
-
-
Sierra, S.1
Lubke, N.2
Walter, H.3
Schulter, E.4
Reuter, S.5
Fatkenheuer, G.6
Bickel, M.7
da Silva, H.8
Kaiser, R.9
Esser, S.10
-
50
-
-
78650235515
-
Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease
-
Tebit, D.M., Arts, E.J., Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease. Lancet Infect. Dis. 11 (2011), 45–56.
-
(2011)
Lancet Infect. Dis.
, vol.11
, pp. 45-56
-
-
Tebit, D.M.1
Arts, E.J.2
-
51
-
-
84976522142
-
HIV-1 group O genotypes and phenotypes: relationship to fitness and susceptibility to antiretroviral drugs
-
Tebit, D.M., Patel, H., Ratcliffe, A., Alessandri, E., Liu, J., Carpenter, C., Plantier, J.C., Arts, E., HIV-1 group O genotypes and phenotypes: relationship to fitness and susceptibility to antiretroviral drugs. AIDS Res. Hum. Retrovir., 2016, 10.1089/aid.2015.0318.
-
(2016)
AIDS Res. Hum. Retrovir.
-
-
Tebit, D.M.1
Patel, H.2
Ratcliffe, A.3
Alessandri, E.4
Liu, J.5
Carpenter, C.6
Plantier, J.C.7
Arts, E.8
-
52
-
-
84870009755
-
Short communication: analysis of the integrase gene from HIV type 1-positive patients living in a rural area of West Cameroon
-
Turriziani, O., Montagna, C., Falasca, F., Bucci, M., Russo, G., Lichtner, M., Sobze, M.S., Vullo, V., Pistello, M., Antonelli, G., Short communication: analysis of the integrase gene from HIV type 1-positive patients living in a rural area of West Cameroon. AIDS Res. Hum. Retrovir. 28 (2012), 1729–1733.
-
(2012)
AIDS Res. Hum. Retrovir.
, vol.28
, pp. 1729-1733
-
-
Turriziani, O.1
Montagna, C.2
Falasca, F.3
Bucci, M.4
Russo, G.5
Lichtner, M.6
Sobze, M.S.7
Vullo, V.8
Pistello, M.9
Antonelli, G.10
-
53
-
-
84998805210
-
Epidemiology of dolutegravir (DTG) resistance in ~ 700 raltegravir-resistant isolates
-
Abstract 85 Toronto, Canada
-
Underwood, M.R., Vavro, C.L., Haney, R., Horton, J., Epidemiology of dolutegravir (DTG) resistance in ~ 700 raltegravir-resistant isolates. International Workshop on HIV & Hepatitis Virus Drug Resistance and Curative Strategies June 4–8, 2013, 2013, Abstract 85, Toronto, Canada.
-
(2013)
International Workshop on HIV & Hepatitis Virus Drug Resistance and Curative Strategies June 4–8, 2013
-
-
Underwood, M.R.1
Vavro, C.L.2
Haney, R.3
Horton, J.4
-
54
-
-
84998630510
-
Resistance post week 48 in ART-experienced, integrase inhibitor-naive subjects with dolutegravir (DTG) vs. raltegravir (RAL) in SAILING (ING111762)
-
(Barcelona, Spain)
-
Underwood, M.R., DeAnda, F., et al. Resistance post week 48 in ART-experienced, integrase inhibitor-naive subjects with dolutegravir (DTG) vs. raltegravir (RAL) in SAILING (ING111762). 13th European HIV & Hepatitis Workshop, June 3–5, 2015, 2015 (Barcelona, Spain).
-
(2015)
13th European HIV & Hepatitis Workshop, June 3–5, 2015
-
-
Underwood, M.R.1
DeAnda, F.2
-
55
-
-
68949172373
-
A combined genotypic and phenotypic human immunodeficiency virus type 1 recombinant virus assay for the reverse transcriptase and integrase genes
-
Van Baelen, K., Rondelez, E., Van Eygen, V., Arien, K., Clynhens, M., Van den Zegel, P., Winters, B., Stuyver, L.J., A combined genotypic and phenotypic human immunodeficiency virus type 1 recombinant virus assay for the reverse transcriptase and integrase genes. J. Virol. Methods 161 (2009), 231–239.
-
(2009)
J. Virol. Methods
, vol.161
, pp. 231-239
-
-
Van Baelen, K.1
Rondelez, E.2
Van Eygen, V.3
Arien, K.4
Clynhens, M.5
Van den Zegel, P.6
Winters, B.7
Stuyver, L.J.8
-
56
-
-
84998606016
-
8th IAS Conference on HIV Pathogenesis, Treatment and Prevention. Vancouver, Canada, July 19-22, 2015
-
Vavro, C., et al. 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention. Vancouver, Canada, July 19-22, 2015. 2015.
-
(2015)
-
-
Vavro, C.1
-
57
-
-
84930647729
-
Will drug resistance against dolutegravir in initial therapy ever occur?
-
Wainberg, M.A., Han, Y.S., Will drug resistance against dolutegravir in initial therapy ever occur?. Front. Pharmacol., 6, 2015, 90.
-
(2015)
Front. Pharmacol.
, vol.6
, pp. 90
-
-
Wainberg, M.A.1
Han, Y.S.2
-
58
-
-
84888099693
-
What if HIV were unable to develop resistance against a new therapeutic agent?
-
Wainberg, M.A., Mesplede, T., Raffi, F., What if HIV were unable to develop resistance against a new therapeutic agent?. BMC Med., 11, 2013, 249.
-
(2013)
BMC Med.
, vol.11
, pp. 249
-
-
Wainberg, M.A.1
Mesplede, T.2
Raffi, F.3
|