메뉴 건너뛰기




Volumn 46, Issue , 2016, Pages 286-291

Differences among HIV-1 subtypes in drug resistance against integrase inhibitors

Author keywords

Drug resistance; HIV subtypes; Integrase inhibitors

Indexed keywords

DOLUTEGRAVIR; ELVITEGRAVIR; INTEGRASE INHIBITOR; RALTEGRAVIR; VIRUS RNA; FUSED HETEROCYCLIC RINGS; QUINOLONE DERIVATIVE;

EID: 84999028775     PISSN: 15671348     EISSN: 15677257     Source Type: Journal    
DOI: 10.1016/j.meegid.2016.06.047     Document Type: Article
Times cited : (40)

References (58)
  • 2
    • 84937540880 scopus 로고    scopus 로고
    • Dolutegravir versus placebo in subjects harbouring HIV-1 with integrase inhibitor resistance associated substitutions: 48-week results from VIKING-4, a randomized study
    • Akil, B., Blick, G., Hagins, D.P., Ramgopal, M.N., Richmond, G.J., Samuel, R.M., Givens, N., Vavro, C., Song, I.H., Wynne, B., Ait-Khaled, M., Dolutegravir versus placebo in subjects harbouring HIV-1 with integrase inhibitor resistance associated substitutions: 48-week results from VIKING-4, a randomized study. Antivir. Ther. 20 (2015), 343–348.
    • (2015) Antivir. Ther. , vol.20 , pp. 343-348
    • Akil, B.1    Blick, G.2    Hagins, D.P.3    Ramgopal, M.N.4    Richmond, G.J.5    Samuel, R.M.6    Givens, N.7    Vavro, C.8    Song, I.H.9    Wynne, B.10    Ait-Khaled, M.11
  • 3
    • 84998814996 scopus 로고    scopus 로고
    • HIV-1 Non Group M Phenotypic Susceptibility to Integrase Inhibitors (Dolutegravir, Elvitegravir and Raltegravir). XXV International HIV Drug Resistance Workshop February 20–21, 2016
    • ABSTRACT 50 Boston, MA, USA
    • Alessandri-Gradt, E., Collin, G., et al. HIV-1 Non Group M Phenotypic Susceptibility to Integrase Inhibitors (Dolutegravir, Elvitegravir and Raltegravir). XXV International HIV Drug Resistance Workshop February 20–21, 2016. 2016, ABSTRACT 50, Boston, MA, USA.
    • (2016)
    • Alessandri-Gradt, E.1    Collin, G.2
  • 5
    • 77956228894 scopus 로고    scopus 로고
    • HIV-1 subtype B and C integrase enzymes exhibit differential patterns of resistance to integrase inhibitors in biochemical assays
    • Bar-Magen, T., Donahue, D.A., McDonough, E.I., Kuhl, B.D., Faltenbacher, V.H., Xu, H., Michaud, V., Sloan, R.D., Wainberg, M.A., HIV-1 subtype B and C integrase enzymes exhibit differential patterns of resistance to integrase inhibitors in biochemical assays. AIDS 24 (2010), 2171–2179.
    • (2010) AIDS , vol.24 , pp. 2171-2179
    • Bar-Magen, T.1    Donahue, D.A.2    McDonough, E.I.3    Kuhl, B.D.4    Faltenbacher, V.H.5    Xu, H.6    Michaud, V.7    Sloan, R.D.8    Wainberg, M.A.9
  • 6
    • 84875082394 scopus 로고    scopus 로고
    • Genetic analysis of HIV-1 integrase sequences from treatment naive individuals in northeastern South Africa
    • Bessong, P.O., Nwobegahay, J., Genetic analysis of HIV-1 integrase sequences from treatment naive individuals in northeastern South Africa. Int. J. Mol. Sci. 14 (2013), 5013–5024.
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 5013-5024
    • Bessong, P.O.1    Nwobegahay, J.2
  • 9
    • 34648824673 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 subtype distribution in the worldwide epidemic: pathogenetic and therapeutic implications
    • Buonaguro, L., Tornesello, M.L., Buonaguro, F.M., Human immunodeficiency virus type 1 subtype distribution in the worldwide epidemic: pathogenetic and therapeutic implications. J. Virol. 81 (2007), 10209–10219.
    • (2007) J. Virol. , vol.81 , pp. 10209-10219
    • Buonaguro, L.1    Tornesello, M.L.2    Buonaguro, F.M.3
  • 11
    • 80155188567 scopus 로고    scopus 로고
    • Cross-resistance profile of the novel integrase inhibitor dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravir
    • Canducci, F., Ceresola, E.R., Boeri, E., Spagnuolo, V., Cossarini, F., Castagna, A., Lazzarin, A., Clementi, M., Cross-resistance profile of the novel integrase inhibitor dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravir. J. Infect. Dis. 204 (2011), 1811–1815.
    • (2011) J. Infect. Dis. , vol.204 , pp. 1811-1815
    • Canducci, F.1    Ceresola, E.R.2    Boeri, E.3    Spagnuolo, V.4    Cossarini, F.5    Castagna, A.6    Lazzarin, A.7    Clementi, M.8
  • 17
    • 84976465588 scopus 로고    scopus 로고
    • HIV-1 group O integrase displays lower susceptibility to raltegravir and has a different mutational pathway for resistance than HIV-1 group M
    • Depatureaux, A., Mesplede, T., Quashie, P., Oliveira, M., Moisi, D., Brenner, B., Wainberg, M., HIV-1 group O integrase displays lower susceptibility to raltegravir and has a different mutational pathway for resistance than HIV-1 group M. J. Int. AIDS Soc., 17, 2014, 19738.
    • (2014) J. Int. AIDS Soc. , vol.17 , pp. 19738
    • Depatureaux, A.1    Mesplede, T.2    Quashie, P.3    Oliveira, M.4    Moisi, D.5    Brenner, B.6    Wainberg, M.7
  • 21
    • 79953882562 scopus 로고    scopus 로고
    • Resistance associated mutations to dolutegravir (S/GSK1349572) in HIV-infected patients–impact of HIV subtypes and prior raltegravir experience
    • Garrido, C., Soriano, V., Geretti, A.M., Zahonero, N., Garcia, S., Booth, C., Gutierrez, F., Viciana, I., de Mendoza, C., Resistance associated mutations to dolutegravir (S/GSK1349572) in HIV-infected patients–impact of HIV subtypes and prior raltegravir experience. Antivir. Res. 90 (2011), 164–167.
    • (2011) Antivir. Res. , vol.90 , pp. 164-167
    • Garrido, C.1    Soriano, V.2    Geretti, A.M.3    Zahonero, N.4    Garcia, S.5    Booth, C.6    Gutierrez, F.7    Viciana, I.8    de Mendoza, C.9
  • 22
  • 23
    • 84907358049 scopus 로고    scopus 로고
    • Resistance to HIV integrase strand transfer inhibitors: in vitro findings and clinical consequences
    • Grobler, J.A., Hazuda, D.J., Resistance to HIV integrase strand transfer inhibitors: in vitro findings and clinical consequences. Curr. Opin. Virol. 8c (2014), 98–103.
    • (2014) Curr. Opin. Virol. , vol.8c , pp. 98-103
    • Grobler, J.A.1    Hazuda, D.J.2
  • 25
    • 79953200796 scopus 로고    scopus 로고
    • Transmitted resistance to HIV integrase strand-transfer inhibitors: right on schedule
    • Hurt, C.B., Transmitted resistance to HIV integrase strand-transfer inhibitors: right on schedule. Antivir. Ther. 16 (2011), 137–140.
    • (2011) Antivir. Ther. , vol.16 , pp. 137-140
    • Hurt, C.B.1
  • 26
    • 84892766007 scopus 로고    scopus 로고
    • Resistance to HIV integrase strand transfer inhibitors among clinical specimens in the United States, 2009-2012
    • Hurt, C.B., Sebastian, J., Hicks, C.B., Eron, J.J., Resistance to HIV integrase strand transfer inhibitors among clinical specimens in the United States, 2009-2012. Clin. Infect. Dis. 58 (2014), 423–431.
    • (2014) Clin. Infect. Dis. , vol.58 , pp. 423-431
    • Hurt, C.B.1    Sebastian, J.2    Hicks, C.B.3    Eron, J.J.4
  • 28
    • 34447263572 scopus 로고    scopus 로고
    • Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance
    • Lataillade, M., Chiarella, J., Kozal, M.J., Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance. Antivir. Ther. 12 (2007), 563–570.
    • (2007) Antivir. Ther. , vol.12 , pp. 563-570
    • Lataillade, M.1    Chiarella, J.2    Kozal, M.J.3
  • 29
    • 84959904913 scopus 로고    scopus 로고
    • Deep analysis of HIV-1 natural variability across HIV-1 variants at residues associated with integrase inhibitor (INI) resistance in INI-naive individuals
    • Llacer Delicado, T., Torrecilla, E., Holguin, A., Deep analysis of HIV-1 natural variability across HIV-1 variants at residues associated with integrase inhibitor (INI) resistance in INI-naive individuals. J. Antimicrob. Chemother. 71 (2016), 362–366.
    • (2016) J. Antimicrob. Chemother. , vol.71 , pp. 362-366
    • Llacer Delicado, T.1    Torrecilla, E.2    Holguin, A.3
  • 30
    • 58549116531 scopus 로고    scopus 로고
    • Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: genetic and structural in silico analyses
    • Loizidou, E.Z., Kousiappa, I., Zeinalipour-Yazdi, C.D., Van de Vijver, D.A., Kostrikis, L.G., Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: genetic and structural in silico analyses. Biochemistry 48 (2009), 4–6.
    • (2009) Biochemistry , vol.48 , pp. 4-6
    • Loizidou, E.Z.1    Kousiappa, I.2    Zeinalipour-Yazdi, C.D.3    Van de Vijver, D.A.4    Kostrikis, L.G.5
  • 34
    • 84907429695 scopus 로고    scopus 로고
    • Is resistance to dolutegravir possible when this drug is used in first-line therapy?
    • Mesplede, T., Wainberg, M.A., Is resistance to dolutegravir possible when this drug is used in first-line therapy?. Viruses 6 (2014), 3377–3385.
    • (2014) Viruses , vol.6 , pp. 3377-3385
    • Mesplede, T.1    Wainberg, M.A.2
  • 38
    • 84948973600 scopus 로고    scopus 로고
    • Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates
    • Mulu, A., Maier, M., Liebert, U.G., Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates. J. Transl. Med., 13, 2015, 377.
    • (2015) J. Transl. Med. , vol.13 , pp. 377
    • Mulu, A.1    Maier, M.2    Liebert, U.G.3
  • 39
    • 50949099460 scopus 로고    scopus 로고
    • Analysis of natural sequence variation and covariation in human immunodeficiency virus type 1 integrase
    • Myers, R.E., Pillay, D., Analysis of natural sequence variation and covariation in human immunodeficiency virus type 1 integrase. J. Virol. 82 (2008), 9228–9235.
    • (2008) J. Virol. , vol.82 , pp. 9228-9235
    • Myers, R.E.1    Pillay, D.2
  • 40
    • 84861199642 scopus 로고    scopus 로고
    • Genetic barrier to the development of resistance to integrase inhibitors in HIV-1 subtypes CRF01_AE and B
    • Nguyen, H.L., Ruxrungtham, K., Delaugerre, C., Genetic barrier to the development of resistance to integrase inhibitors in HIV-1 subtypes CRF01_AE and B. Intervirology 55 (2012), 287–295.
    • (2012) Intervirology , vol.55 , pp. 287-295
    • Nguyen, H.L.1    Ruxrungtham, K.2    Delaugerre, C.3
  • 42
    • 84943792977 scopus 로고    scopus 로고
    • Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout
    • Osman, N., Mesplede, T., Quashie, P.K., Oliveira, M., Zanichelli, V., Wainberg, M.A., Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout. J. Antimicrob. Chemother. 70 (2015), 2810–2815.
    • (2015) J. Antimicrob. Chemother. , vol.70 , pp. 2810-2815
    • Osman, N.1    Mesplede, T.2    Quashie, P.K.3    Oliveira, M.4    Zanichelli, V.5    Wainberg, M.A.6
  • 43
    • 84941744457 scopus 로고    scopus 로고
    • Review of integrase strand transfer inhibitors for the treatment of human immunodeficiency virus infection
    • Park, T.E., Mohamed, A., Kalabalik, J., Sharma, R., Review of integrase strand transfer inhibitors for the treatment of human immunodeficiency virus infection. Expert Rev. Anti-Infect. Ther. 13 (2015), 1195–1212.
    • (2015) Expert Rev. Anti-Infect. Ther. , vol.13 , pp. 1195-1212
    • Park, T.E.1    Mohamed, A.2    Kalabalik, J.3    Sharma, R.4
  • 45
    • 84864197719 scopus 로고    scopus 로고
    • HIV type 1 integrase polymorphisms in treatment-naive and treatment-experienced HIV type 1-infected patients in Thailand where HIV type 1 subtype A/E predominates
    • Phuphuakrat, A., Pasomsub, E., Kiertiburanakul, S., Chantratita, W., Sungkanuparph, S., HIV type 1 integrase polymorphisms in treatment-naive and treatment-experienced HIV type 1-infected patients in Thailand where HIV type 1 subtype A/E predominates. AIDS Res. Hum. Retrovir. 28 (2012), 937–943.
    • (2012) AIDS Res. Hum. Retrovir. , vol.28 , pp. 937-943
    • Phuphuakrat, A.1    Pasomsub, E.2    Kiertiburanakul, S.3    Chantratita, W.4    Sungkanuparph, S.5
  • 48
    • 84888400011 scopus 로고    scopus 로고
    • HIV-1 genetic variability and clinical implications
    • Santoro, M.M., Perno, C.F., HIV-1 genetic variability and clinical implications. ISRN Microbiol., 2013, 2013, 481314.
    • (2013) ISRN Microbiol. , vol.2013 , pp. 481314
    • Santoro, M.M.1    Perno, C.F.2
  • 50
    • 78650235515 scopus 로고    scopus 로고
    • Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease
    • Tebit, D.M., Arts, E.J., Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease. Lancet Infect. Dis. 11 (2011), 45–56.
    • (2011) Lancet Infect. Dis. , vol.11 , pp. 45-56
    • Tebit, D.M.1    Arts, E.J.2
  • 54
    • 84998630510 scopus 로고    scopus 로고
    • Resistance post week 48 in ART-experienced, integrase inhibitor-naive subjects with dolutegravir (DTG) vs. raltegravir (RAL) in SAILING (ING111762)
    • (Barcelona, Spain)
    • Underwood, M.R., DeAnda, F., et al. Resistance post week 48 in ART-experienced, integrase inhibitor-naive subjects with dolutegravir (DTG) vs. raltegravir (RAL) in SAILING (ING111762). 13th European HIV & Hepatitis Workshop, June 3–5, 2015, 2015 (Barcelona, Spain).
    • (2015) 13th European HIV & Hepatitis Workshop, June 3–5, 2015
    • Underwood, M.R.1    DeAnda, F.2
  • 55
    • 68949172373 scopus 로고    scopus 로고
    • A combined genotypic and phenotypic human immunodeficiency virus type 1 recombinant virus assay for the reverse transcriptase and integrase genes
    • Van Baelen, K., Rondelez, E., Van Eygen, V., Arien, K., Clynhens, M., Van den Zegel, P., Winters, B., Stuyver, L.J., A combined genotypic and phenotypic human immunodeficiency virus type 1 recombinant virus assay for the reverse transcriptase and integrase genes. J. Virol. Methods 161 (2009), 231–239.
    • (2009) J. Virol. Methods , vol.161 , pp. 231-239
    • Van Baelen, K.1    Rondelez, E.2    Van Eygen, V.3    Arien, K.4    Clynhens, M.5    Van den Zegel, P.6    Winters, B.7    Stuyver, L.J.8
  • 56
    • 84998606016 scopus 로고    scopus 로고
    • 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention. Vancouver, Canada, July 19-22, 2015
    • Vavro, C., et al. 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention. Vancouver, Canada, July 19-22, 2015. 2015.
    • (2015)
    • Vavro, C.1
  • 57
    • 84930647729 scopus 로고    scopus 로고
    • Will drug resistance against dolutegravir in initial therapy ever occur?
    • Wainberg, M.A., Han, Y.S., Will drug resistance against dolutegravir in initial therapy ever occur?. Front. Pharmacol., 6, 2015, 90.
    • (2015) Front. Pharmacol. , vol.6 , pp. 90
    • Wainberg, M.A.1    Han, Y.S.2
  • 58
    • 84888099693 scopus 로고    scopus 로고
    • What if HIV were unable to develop resistance against a new therapeutic agent?
    • Wainberg, M.A., Mesplede, T., Raffi, F., What if HIV were unable to develop resistance against a new therapeutic agent?. BMC Med., 11, 2013, 249.
    • (2013) BMC Med. , vol.11 , pp. 249
    • Wainberg, M.A.1    Mesplede, T.2    Raffi, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.