S/GSK1349572 is a potent next generation HIV integrase inhibitor
Abstract WEPEA097
Sato A, Kobayashi M, Yoshinaga T et al. S/GSK1349572 is a potent next generation HIV integrase inhibitor. In: Abstracts of the Fifth IAS Conference on HIV Pathogenesis, Treatment and Prevention, Cape Town, South Africa, 2009. Abstract WEPEA097.
Identification of novel mutations responsible for resistance to MK-2048, a second-generation HIV-1 integrase inhibitor
Bar-Magen T, Sloan RD, Donahue DA et al. Identification of novel mutations responsible for resistance to MK-2048, a second-generation HIV-1 integrase inhibitor. J Virol 2010; 84: 9210-6.
Increasing prevalence of transmitted drug resistance mutations and non-B subtype circulation in antiretroviral-naive chronically HIV-infected patients from 2001 to 2006/2007 in France
Descamps D, Chaix ML, Montes B et al. Increasing prevalence of transmitted drug resistance mutations and non-B subtype circulation in antiretroviral-naive chronically HIV-infected patients from 2001 to 2006/2007 in France. J Antimicrob Chemother 2010; 65: 2620-7.
Genetic barriers for integrase inhibitor drug resistance in HIV type-1 B and CRF02_AG subtypes
Maiga AI, Malet I, Soulie C et al. Genetic barriers for integrase inhibitor drug resistance in HIV type-1 B and CRF02_AG subtypes. Antivir Ther 2009; 14: 123-9.
Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro
Malet I, Delelis O, Valantin MA et al. Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro. Antimicrob Agents Chemother 2008; 52: 1351-8.
Clade-specific HIV-1 integrase polymorphisms do not reduce raltegravir and elvitegravir phenotypic susceptibility
Van Baelen K, Van Eygen V, Rondelez E et al. Clade-specific HIV-1 integrase polymorphisms do not reduce raltegravir and elvitegravir phenotypic susceptibility. AIDS 2008; 22: 1877-80.
Structural effects of amino acid variations between B and CRF02-AG HIV-1 integrases
Malet I, Soulie C, Tchertanov L et al. Structural effects of amino acid variations between B and CRF02-AG HIV-1 integrases. J Med Virol 2008; 80: 754-61.
Selection of diverse and clinically relevant integrase inhibitor-resistant human immunodeficiency virus type 1 mutants
Kobayashi M, Nakahara K, Seki T et al. Selection of diverse and clinically relevant integrase inhibitor-resistant human immunodeficiency virus type 1 mutants. Antiviral Res 2008; 80: 213-22.
Prevalence and patterns of raltegravir resistance in treated patients in Europe
Abstract 51
Geretti AM, Fearnhill E, Ceccherini-Silberstein F et al. Prevalence and patterns of raltegravir resistance in treated patients in Europe. In: Abstracts of the International HIV and Hepatitis Drug Resistance Workshop, Dubrovnik, Croatia, 2010. Abstract 51.
Characterization and structural analysis of HIV-1 integrase conservation
Ceccherini-Silberstein F, Malet I, D'Arrigo R et al. Characterization and structural analysis of HIV-1 integrase conservation. AIDS Rev 2009; 11: 17-29.