Multispectral imaging of formalin-fixed tissue predicts ability to generate tumor-infiltrating lymphocytes from melanoma

Journal for ImmunoTherapy of Cancer

Volumn 3, Issue 1, 2015, Pages

  Feng, Zipei ^a,b   Puri, Sachin ^a   Moudgil, Tarsem ^a   Wood, William ^a   Hoyt, Clifford C ^c   Wang, Chichung ^c   Urba, Walter J ^a   Curti, Brendan D ^a   Bifulco, Carlo B ^a,d   Fox, Bernard A ^a,b,e  

^a EARLE A CHILES RESEARCH INSTITUTE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c PERKINELMER INC   (United States)

^d Providence Portland Regional Laboratory ^*  (United States)

^e Ubivac   (United States)

Author keywords

Adoptive T cell therapy (ACT); Immunoprofiling; Immunoscore; Immunotherapy; Immunotherapy biomarker; Melanoma; Multispectral imaging; Tumor infiltrating lymphocytes (TIL)

Indexed keywords

CD163 ANTIGEN; CD3 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; PROGRAMMED DEATH 1 LIGAND 1; TRANSCRIPTION FACTOR FOXP3;

ADOPTIVE IMMUNOTHERAPY; ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE IMAGING; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; LYMPHOCYTIC INFILTRATION; MALE; MELANOMA; PREDICTIVE VALUE; PRIORITY JOURNAL; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; TUMOR REGRESSION;

EID: 84998704798     PISSN: None     EISSN: 20511426     Source Type: Journal    
DOI: 10.1186/s40425-015-0091-z     Document Type: Article

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