메뉴 건너뛰기




Volumn 21, Issue 11, 2016, Pages

Gut bacteria and hydrogen sulfide: The new old players in circulatory system homeostasis

Author keywords

Cardiovascular diseases; Gut bacteria; Hydrogen sulfide; Hypertension; Indole; Microbiota; Sulfur; TMAO

Indexed keywords

HYDROGEN SULFIDE;

EID: 84997783056     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules21111558     Document Type: Review
Times cited : (134)

References (165)
  • 1
    • 84931295496 scopus 로고    scopus 로고
    • Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook
    • Kelly, C.R.; Kahn, S.; Kashyap, P.; Laine, L.; Rubin, D.; Atreja, A.; Moore, T.; Wu, G. Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook. Gastroenterology 2015, 149, 223-237.
    • (2015) Gastroenterology , vol.149 , pp. 223-237
    • Kelly, C.R.1    Kahn, S.2    Kashyap, P.3    Laine, L.4    Rubin, D.5    Atreja, A.6    Moore, T.7    Wu, G.8
  • 3
    • 84943253507 scopus 로고    scopus 로고
    • Historical perspective: Gut dysbiosis and hypertension
    • Honour, J.W. Historical perspective: Gut dysbiosis and hypertension. Physiol. Genomics. 2015, 47, 443-446.
    • (2015) Physiol. Genomics , vol.47 , pp. 443-446
    • Honour, J.W.1
  • 4
  • 6
    • 84946496090 scopus 로고    scopus 로고
    • Ammonia and Its Role in the Pathogenesis of Hepatic Encephalopathy
    • Parekh, P.J.; Balart, L.A. Ammonia and Its Role in the Pathogenesis of Hepatic Encephalopathy. Clin. Liver Dis. 2015, 19, 529-537.
    • (2015) Clin. Liver Dis. , vol.19 , pp. 529-537
    • Parekh, P.J.1    Balart, L.A.2
  • 9
    • 84916602263 scopus 로고    scopus 로고
    • Fecal microbiota transplantation a new old kid on the block for the management of gut microbiota-related disease
    • Cammarota, G.; Ianiro, G.; Bibbò, S.; Gasbarrini, A. Fecal microbiota transplantation a new old kid on the block for the management of gut microbiota-related disease. J. Clin. Gastroenterol. 2014, 48, S80-S84.
    • (2014) J. Clin. Gastroenterol. , vol.48 , pp. S80-S84
    • Cammarota, G.1    Ianiro, G.2    Bibbò, S.3    Gasbarrini, A.4
  • 10
    • 84901032421 scopus 로고    scopus 로고
    • The role and influence of gut microbiota in pathogenesis and management of obesity and metabolic syndrome
    • Parekh, P.J.; Arusi, E.; Vinik, A.I.; Johnson, D.A. The role and influence of gut microbiota in pathogenesis and management of obesity and metabolic syndrome. Front. Endocrinol. (Lausanne) 2014, 5.
    • (2014) Front. Endocrinol. (Lausanne) , vol.5
    • Parekh, P.J.1    Arusi, E.2    Vinik, A.I.3    Johnson, D.A.4
  • 13
    • 84900487381 scopus 로고    scopus 로고
    • The iron biogeochemical cycle past and present
    • Raiswell, R.; Canfield, D.E. The iron biogeochemical cycle past and present. Geochem. Perspect. 2012, 1, 1-232.
    • (2012) Geochem. Perspect. , vol.1 , pp. 1-232
    • Raiswell, R.1    Canfield, D.E.2
  • 14
    • 84896983974 scopus 로고    scopus 로고
    • Geological evidence of oxygenic photosynthesis and the biotic response to the 2400-2200 Ma "great Oxidation Event"
    • Schopf, J.W. Geological evidence of oxygenic photosynthesis and the biotic response to the 2400-2200 Ma "great Oxidation Event". Biochemistry (Mosc.) 2014, 79, 165-177.
    • (2014) Biochemistry (Mosc.) , vol.79 , pp. 165-177
    • Schopf, J.W.1
  • 15
    • 84949949016 scopus 로고    scopus 로고
    • The role of hydrogen sulfide in evolution and the evolution of hydrogen sulfide in metabolism and signaling
    • Olson, K.R.; Straub, K.D. The role of hydrogen sulfide in evolution and the evolution of hydrogen sulfide in metabolism and signaling. Physiology (Bethesda) 2016, 31, 60-72.
    • (2016) Physiology (Bethesda) , vol.31 , pp. 60-72
    • Olson, K.R.1    Straub, K.D.2
  • 16
    • 79956061759 scopus 로고    scopus 로고
    • Prebiotic Synthesis of Methionine and Other Sulfur-Containing Organic Compounds on the Primitive Earth: A Contemporary Reassessment Based on an Unpublished 1958 Stanley Miller Experiment
    • Parker, E.T.; Cleaves, H.J.; Callahan, M.P.; Dworkin, J.P.; Glavin, D.P.; Lazcano, A.; Bada, J.L. Prebiotic Synthesis of Methionine and Other Sulfur-Containing Organic Compounds on the Primitive Earth: A Contemporary Reassessment Based on an Unpublished 1958 Stanley Miller Experiment. Orig. Life Evol. Biosph. 2011, 41, 201-212.
    • (2011) Orig. Life Evol. Biosph. , vol.41 , pp. 201-212
    • Parker, E.T.1    Cleaves, H.J.2    Callahan, M.P.3    Dworkin, J.P.4    Glavin, D.P.5    Lazcano, A.6    Bada, J.L.7
  • 18
    • 80053501257 scopus 로고    scopus 로고
    • Microfossils of sulphur-metabolizing cells in 3.4-billion-year-old rocks of Western Australia
    • Wacey, D.; Kilburn, M.R.; Saunders, M.; Cliff, J.; Brasier, M.D. Microfossils of sulphur-metabolizing cells in 3.4-billion-year-old rocks of Western Australia. Nat. Geosci. 2011, 4, 698-702.
    • (2011) Nat. Geosci. , vol.4 , pp. 698-702
    • Wacey, D.1    Kilburn, M.R.2    Saunders, M.3    Cliff, J.4    Brasier, M.D.5
  • 19
    • 84952629954 scopus 로고    scopus 로고
    • A Post-Genomic View of the Ecophysiology, Catabolism and Biotechnological Relevance of Sulphate-Reducing Prokaryotes
    • Rabus, R.; Venceslau, S.S.; Wöhlbrand, L.; Voordouw, G.; Wall, J.D.; Pereira, I.A.C. A Post-Genomic View of the Ecophysiology, Catabolism and Biotechnological Relevance of Sulphate-Reducing Prokaryotes. Adv. Microb. Physiol. 2015, 66, 55-321.
    • (2015) Adv. Microb. Physiol. , vol.66 , pp. 55-321
    • Rabus, R.1    Venceslau, S.S.2    Wöhlbrand, L.3    Voordouw, G.4    Wall, J.D.5    Pereira, I.A.C.6
  • 20
    • 0029876402 scopus 로고    scopus 로고
    • The possible role of hydrogen sulfide as an endogenous neuromodulator
    • Abe, K.; Kimura, H. The possible role of hydrogen sulfide as an endogenous neuromodulator. J. Neurosci. 1996, 16, 1066-1071.
    • (1996) J. Neurosci. , vol.16 , pp. 1066-1071
    • Abe, K.1    Kimura, H.2
  • 24
    • 84894479886 scopus 로고    scopus 로고
    • Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease
    • Polhemus, D.J.; Lefer, D.J. Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease. Circ. Res. 2014, 114, 730-737.
    • (2014) Circ. Res. , vol.114 , pp. 730-737
    • Polhemus, D.J.1    Lefer, D.J.2
  • 25
    • 84964204551 scopus 로고    scopus 로고
    • Hypotensive effect of S-adenosyl-L-methionine in hypertensive rats is reduced by autonomic ganglia and KATP channel blockers
    • Sikora, M.; Pham, K.; Ufnal, M. Hypotensive effect of S-adenosyl-L-methionine in hypertensive rats is reduced by autonomic ganglia and KATP channel blockers. Amino Acids 2016, 48, 1581-1590.
    • (2016) Amino Acids , vol.48 , pp. 1581-1590
    • Sikora, M.1    Pham, K.2    Ufnal, M.3
  • 27
    • 77950792008 scopus 로고    scopus 로고
    • Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract
    • Wallace, J.L. Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract. Antioxid. Redox Signal. 2010, 12, 1125-1133.
    • (2010) Antioxid. Redox Signal. , vol.12 , pp. 1125-1133
    • Wallace, J.L.1
  • 31
    • 84959287341 scopus 로고    scopus 로고
    • Human breast milk and infant formulas differentially modify the intestinal microbiota in human infants and host physiology in rats
    • Liu, Z.; Roy, N.C.; Guo, Y.; Jia, H.; Ryan, L.; Samuelsson, L.; Thomas, A.; Plowman, J.; Clerens, S.; Day, L.; Young, W. Human breast milk and infant formulas differentially modify the intestinal microbiota in human infants and host physiology in rats. J. Nutr. 2016, 146, 191-199.
    • (2016) J. Nutr. , vol.146 , pp. 191-199
    • Liu, Z.1    Roy, N.C.2    Guo, Y.3    Jia, H.4    Ryan, L.5    Samuelsson, L.6    Thomas, A.7    Plowman, J.8    Clerens, S.9    Day, L.10    Young, W.11
  • 32
    • 84887376339 scopus 로고    scopus 로고
    • The Gut Microbiotassay: A high-throughput qPCR approach combinable with next generation sequencing to study gut microbial diversity
    • Hermann-Bank, M.L.; Skovgaard, K.; Stockmarr, A.; Larsen, N.; Mølbak, L. The Gut Microbiotassay: A high-throughput qPCR approach combinable with next generation sequencing to study gut microbial diversity. BMC Genom. 2013, 14.
    • (2013) BMC Genom. , vol.14
    • Hermann-Bank, M.L.1    Skovgaard, K.2    Stockmarr, A.3    Larsen, N.4    Mølbak, L.5
  • 33
    • 84938244327 scopus 로고    scopus 로고
    • Small molecules from the human microbiota
    • Donia, M.S.; Fischbach, M.A. Small molecules from the human microbiota. Science 2015, 349, 1254766.
    • (2015) Science , vol.349
    • Donia, M.S.1    Fischbach, M.A.2
  • 35
    • 84983638440 scopus 로고    scopus 로고
    • Intestinal Microbial Metabolites Are Linked to Severity of Myocardial Infarction in Rats
    • Lam, V.; Su, J.; Hsu, A.; Gross, G.J.; Salzman, N.H.; Baker, J.E. Intestinal Microbial Metabolites Are Linked to Severity of Myocardial Infarction in Rats. PLoS ONE 2016, 11, e0160840.
    • (2016) PLoS ONE , vol.11
    • Lam, V.1    Su, J.2    Hsu, A.3    Gross, G.J.4    Salzman, N.H.5    Baker, J.E.6
  • 36
    • 84997708721 scopus 로고    scopus 로고
    • Neuromodulatory effects and targets of the SCFAs and gasotransmitters produced by the human symbiotic microbiota
    • Oleskin, A.V.; Shenderov, B.A. Neuromodulatory effects and targets of the SCFAs and gasotransmitters produced by the human symbiotic microbiota. Microb. Ecol. Health Dis. 2016, 27, 30971.
    • (2016) Microb. Ecol. Health Dis. , vol.27 , pp. 30971
    • Oleskin, A.V.1    Shenderov, B.A.2
  • 37
    • 84858153169 scopus 로고    scopus 로고
    • Essential hypertension-is erroneous receptor output to blame?
    • Ufnal, M. Essential hypertension-is erroneous receptor output to blame? Med. Hypotheses 2012, 78, 454-458.
    • (2012) Med. Hypotheses , vol.78 , pp. 454-458
    • Ufnal, M.1
  • 38
    • 0030666935 scopus 로고    scopus 로고
    • Subdiaphragmatic vagotomy blocks the sleep- and fever-promoting effects of interleukin-1beta
    • Hansen, M.K.; Krueger, J.M. Subdiaphragmatic vagotomy blocks the sleep- and fever-promoting effects of interleukin-1beta. Am. J. Physiol. 1997, 273, R1246-R1253.
    • (1997) Am. J. Physiol. , vol.273 , pp. R1246-R1253
    • Hansen, M.K.1    Krueger, J.M.2
  • 39
    • 84989196486 scopus 로고    scopus 로고
    • Significance of gut-blood barrier in health and disease
    • Huc, T.; Pham, K.; Skrzypecki, J.; Ufnal, M. Significance of gut-blood barrier in health and disease. Eur. J. Biol. Res. 2016, 6, 193-200.
    • (2016) Eur. J. Biol. Res. , vol.6 , pp. 193-200
    • Huc, T.1    Pham, K.2    Skrzypecki, J.3    Ufnal, M.4
  • 41
    • 84942540625 scopus 로고    scopus 로고
    • Role of gut-derived protein-bound uremic toxins in cardiorenal syndrome and potential treatment modalities
    • Lekawanvijit, S. Role of gut-derived protein-bound uremic toxins in cardiorenal syndrome and potential treatment modalities. Circ. J. 2015, 79, 2088-2097.
    • (2015) Circ. J. , vol.79 , pp. 2088-2097
    • Lekawanvijit, S.1
  • 42
    • 84942364182 scopus 로고    scopus 로고
    • TMAO: A small molecule of great expectations
    • Ufnal, M.; Zadlo, A.; Ostaszewski, R. TMAO: A small molecule of great expectations. Nutrition 2015, 31, 1317-1323.
    • (2015) Nutrition , vol.31 , pp. 1317-1323
    • Ufnal, M.1    Zadlo, A.2    Ostaszewski, R.3
  • 44
    • 78649997364 scopus 로고    scopus 로고
    • Gut permeability and food allergies
    • Perrier, C.; Corthesy, B. Gut permeability and food allergies. Clin. Exp. Allergy 2011, 41, 20-28.
    • (2011) Clin. Exp. Allergy , vol.41 , pp. 20-28
    • Perrier, C.1    Corthesy, B.2
  • 48
    • 40949163852 scopus 로고    scopus 로고
    • Collagen accumulation and dysfunctional mucosal barrier of the small intestine in patients with chronic heart failure
    • Arutyunov, G.P.; Kostyukevich, O.I.; Serov, R.A.; Rylova, N.V.; Bylova, N.A. Collagen accumulation and dysfunctional mucosal barrier of the small intestine in patients with chronic heart failure. Int. J. Cardiol. 2008, 125, 240-245.
    • (2008) Int. J. Cardiol. , vol.125 , pp. 240-245
    • Arutyunov, G.P.1    Kostyukevich, O.I.2    Serov, R.A.3    Rylova, N.V.4    Bylova, N.A.5
  • 53
    • 84943785702 scopus 로고    scopus 로고
    • The impact of early life gut colonization on metabolic and obesogenic outcomes: What have animal models shown us?
    • Wallace, J.G.; Gohir, W.; Sloboda, D.M. The impact of early life gut colonization on metabolic and obesogenic outcomes: What have animal models shown us? J. Dev. Orig. Health Dis. 2016, 7, 15-24.
    • (2016) J. Dev. Orig. Health Dis. , vol.7 , pp. 15-24
    • Wallace, J.G.1    Gohir, W.2    Sloboda, D.M.3
  • 54
    • 70349631208 scopus 로고    scopus 로고
    • Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients
    • Armougom, F.; Henry, M.; Vialettes, B.; Raccah, D.; Raoult, D. Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients. PLoS ONE 2009, 4, e7125.
    • (2009) PLoS ONE , vol.4 , pp. e7125
    • Armougom, F.1    Henry, M.2    Vialettes, B.3    Raccah, D.4    Raoult, D.5
  • 55
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • Ley, R.E.; Turnbaugh, P.J.; Klein, S.; Gordon, J.I. Microbial ecology: Human gut microbes associated with obesity. Nature 2006, 444, 1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 59
    • 79959467647 scopus 로고    scopus 로고
    • Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans
    • Jumpertz, R.; Le, D.S.; Turnbaugh, P.J.; Trinidad, C.; Bogardus, C.; Gordon, J.I.; Krakoff, J. Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. Am. J. Clin. Nutr. 2011, 94, 58-65.
    • (2011) Am. J. Clin. Nutr. , vol.94 , pp. 58-65
    • Jumpertz, R.1    Le, D.S.2    Turnbaugh, P.J.3    Trinidad, C.4    Bogardus, C.5    Gordon, J.I.6    Krakoff, J.7
  • 67
    • 0023779558 scopus 로고
    • Occurrence of sulphate-reducing bacteria in human faeces and the relationship of dissimilatory sulphate reduction to methanogenesis in the large gut
    • Gibson, G.R.; Macfarlane, G.T.; Cummings, J.H. Occurrence of sulphate-reducing bacteria in human faeces and the relationship of dissimilatory sulphate reduction to methanogenesis in the large gut. J. Appl. Bacteriol. 1988, 65, 103-111.
    • (1988) J. Appl. Bacteriol. , vol.65 , pp. 103-111
    • Gibson, G.R.1    Macfarlane, G.T.2    Cummings, J.H.3
  • 68
    • 80052593783 scopus 로고    scopus 로고
    • On the relationship between sialomucin and sulfomucin expression and hydrogenotrophic microbes in the human colonic mucosa
    • Croix, J.A.; Carbonero, F.; Nava, G.M.; Russell, M.; Greenberg, E.; Gaskins, H.R. On the relationship between sialomucin and sulfomucin expression and hydrogenotrophic microbes in the human colonic mucosa. PLoS ONE 2011, 6, e24447.
    • (2011) PLoS ONE , vol.6
    • Croix, J.A.1    Carbonero, F.2    Nava, G.M.3    Russell, M.4    Greenberg, E.5    Gaskins, H.R.6
  • 69
    • 22144456756 scopus 로고    scopus 로고
    • Identification and functional analysis of Escherichia coli cysteine desulfhydrases
    • Awano, N.; Wada, M.; Mori, H.; Nakamori, S.; Takagi, H. Identification and functional analysis of Escherichia coli cysteine desulfhydrases. Appl. Environ. Microbiol. 2005, 71, 4149-4152.
    • (2005) Appl. Environ. Microbiol. , vol.71 , pp. 4149-4152
    • Awano, N.1    Wada, M.2    Mori, H.3    Nakamori, S.4    Takagi, H.5
  • 70
    • 0016671528 scopus 로고
    • Crystallization and properties of cysteine desulfhydrase from Aerobacter aerogenes
    • Kumagai, H.; Sejima, S.; Choi, Y.J.; Tanaka, H.; Yamada, H. Crystallization and properties of cysteine desulfhydrase from Aerobacter aerogenes. FEBS Lett. 1975, 52, 304-307.
    • (1975) FEBS Lett. , vol.52 , pp. 304-307
    • Kumagai, H.1    Sejima, S.2    Choi, Y.J.3    Tanaka, H.4    Yamada, H.5
  • 72
    • 0015918806 scopus 로고
    • Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. I. The Escherichia coli hemoflavoprotein: Molecular parameters and prosthetic groups
    • Siegel, L.M.; Murphy, M.J.; Kamin, H. Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. I. The Escherichia coli hemoflavoprotein: Molecular parameters and prosthetic groups. J. Biol. Chem. 1973, 248, 251-264.
    • (1973) J. Biol. Chem. , vol.248 , pp. 251-264
    • Siegel, L.M.1    Murphy, M.J.2    Kamin, H.3
  • 73
    • 77950851572 scopus 로고    scopus 로고
    • Butyrate-stimulated H2S production in colon cancer cells
    • Cao, Q.; Zhang, L.; Yang, G.; Xu, C.; Wang, R. Butyrate-stimulated H2S production in colon cancer cells. Antioxid. Redox Signal. 2010, 12, 1101-1109.
    • (2010) Antioxid. Redox Signal. , vol.12 , pp. 1101-1109
    • Cao, Q.1    Zhang, L.2    Yang, G.3    Xu, C.4    Wang, R.5
  • 74
    • 33748987100 scopus 로고    scopus 로고
    • 5-Amino-2-hydroxybenzoic acid 4-(5-thioxo-5H-[1,2]dithiol-3yl)-phenyl ester (ATB-429), a hydrogen sulfide-releasing derivative of mesalamine, exerts antinociceptive effects in a model of postinflammatory hypersensitivity
    • Distrutti, E.; Sediari, L.; Mencarelli, A.; Renga, B.; Orlandi, S.; Russo, G.; Caliendo, G.; Santagada, V.; Cirino, G.; Wallace, J.L.; et al. 5-Amino-2-hydroxybenzoic acid 4-(5-thioxo-5H-[1,2]dithiol-3yl)-phenyl ester (ATB-429), a hydrogen sulfide-releasing derivative of mesalamine, exerts antinociceptive effects in a model of postinflammatory hypersensitivity. J. Pharmacol. Exp. Ther. 2006, 319, 447-458.
    • (2006) J. Pharmacol. Exp. Ther. , vol.319 , pp. 447-458
    • Distrutti, E.1    Sediari, L.2    Mencarelli, A.3    Renga, B.4    Orlandi, S.5    Russo, G.6    Caliendo, G.7    Santagada, V.8    Cirino, G.9    Wallace, J.L.10
  • 76
    • 67651001726 scopus 로고    scopus 로고
    • Endogenous and Exogenous Hydrogen Sulfide Promotes Resolution of Colitis in Rats
    • Wallace, J.L.; Vong, L.; McKnight, W.; Dicay, M.; Martin, G.R. Endogenous and Exogenous Hydrogen Sulfide Promotes Resolution of Colitis in Rats. Gastroenterology 2009, 137, 569-578.
    • (2009) Gastroenterology , vol.137 , pp. 569-578
    • Wallace, J.L.1    Vong, L.2    McKnight, W.3    Dicay, M.4    Martin, G.R.5
  • 78
    • 0033653461 scopus 로고    scopus 로고
    • Contribution of dietary protein to sulfide production in the large intestine: An in vitro and a controlled feeding study in humans
    • Magee, E.A.; Richardson, C.J.; Hughes, R.; Cummings, J.H. Contribution of dietary protein to sulfide production in the large intestine: An in vitro and a controlled feeding study in humans. Am. J. Clin. Nutr. 2000, 72, 1488-1494.
    • (2000) Am. J. Clin. Nutr. , vol.72 , pp. 1488-1494
    • Magee, E.A.1    Richardson, C.J.2    Hughes, R.3    Cummings, J.H.4
  • 79
    • 0036095223 scopus 로고    scopus 로고
    • Physiology of sulfide in the rat colon: Use of bismuth to assess colonic sulfide production
    • Levitt, M.D.; Springfield, J.; Furne, J.; Koenig, T.; Suarez, F.L. Physiology of sulfide in the rat colon: Use of bismuth to assess colonic sulfide production. J. Appl. Physiol. (1985) 2002, 92, 1655-1660.
    • (2002) J. Appl. Physiol. (1985) , vol.92 , pp. 1655-1660
    • Levitt, M.D.1    Springfield, J.2    Furne, J.3    Koenig, T.4    Suarez, F.L.5
  • 81
    • 0034903991 scopus 로고    scopus 로고
    • Hydrogen sulfide and colonic epithelial metabolism: Implications for ulcerative colitis
    • Jørgensen, J.; Mortensen, P.B. Hydrogen sulfide and colonic epithelial metabolism: Implications for ulcerative colitis. Dig. Dis. Sci. 2001, 46, 1722-1732.
    • (2001) Dig. Dis. Sci. , vol.46 , pp. 1722-1732
    • Jørgensen, J.1    Mortensen, P.B.2
  • 82
    • 0035879968 scopus 로고    scopus 로고
    • Oxidation of hydrogen sulfide and methanethiol to thiosulfate by rat tissues: A specialized function of the colonic mucosa
    • Furne, J.; Springfield, J.; Koenig, T.; DeMaster, E.; Levitt, M.D. Oxidation of hydrogen sulfide and methanethiol to thiosulfate by rat tissues: A specialized function of the colonic mucosa. Biochem. Pharmacol. 2001, 62, 255-259.
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 255-259
    • Furne, J.1    Springfield, J.2    Koenig, T.3    DeMaster, E.4    Levitt, M.D.5
  • 85
    • 0027490258 scopus 로고
    • Sulphide impairment of substrate oxidation in rat colonocytes: A biochemical basis for ulcerative colitis?
    • Roediger, W.E.W.; Duncan, A.; Kapaniris, O.; Millard, S. Sulphide impairment of substrate oxidation in rat colonocytes: A biochemical basis for ulcerative colitis? Clin. Sci. (Lond.) 1993, 85, 623-627.
    • (1993) Clin. Sci. (Lond.) , vol.85 , pp. 623-627
    • Roediger, W.E.W.1    Duncan, A.2    Kapaniris, O.3    Millard, S.4
  • 89
    • 84948390431 scopus 로고    scopus 로고
    • Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System
    • Nagpure, B.V.; Bian, J.S. Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System. Oxid. Med. Cell. Longev. 2016, 2016, 6904327.
    • (2016) Oxid. Med. Cell. Longev. , vol.2016
    • Nagpure, B.V.1    Bian, J.S.2
  • 90
    • 84949492191 scopus 로고    scopus 로고
    • Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases
    • Meng, G.; Ma, Y.; Xie, L.; Ferro, A.; Ji, Y. Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases. Br. J. Pharmacol. 2015, 172, 5501-5511.
    • (2015) Br. J. Pharmacol. , vol.172 , pp. 5501-5511
    • Meng, G.1    Ma, Y.2    Xie, L.3    Ferro, A.4    Ji, Y.5
  • 92
    • 84863769706 scopus 로고    scopus 로고
    • Hydrogen sulphide: Biopharmacological roles in the cardiovascular system and pharmaceutical perspectives
    • Martelli, A.; Testai, L.; Marino, A.; Breschi, M.C.; Da Settimo, F.; Calderone, V. Hydrogen sulphide: Biopharmacological roles in the cardiovascular system and pharmaceutical perspectives. Curr. Med. Chem. 2012, 19, 3325-3336.
    • (2012) Curr. Med. Chem. , vol.19 , pp. 3325-3336
    • Martelli, A.1    Testai, L.2    Marino, A.3    Breschi, M.C.4    Da Settimo, F.5    Calderone, V.6
  • 93
    • 80052234068 scopus 로고    scopus 로고
    • The role of brain gaseous transmitters in the regulation of the circulatory system
    • Ufnal, M.; Sikora, M. The role of brain gaseous transmitters in the regulation of the circulatory system. Curr. Pharm. Biotechnol. 2011, 12, 1322-1333.
    • (2011) Curr. Pharm. Biotechnol. , vol.12 , pp. 1322-1333
    • Ufnal, M.1    Sikora, M.2
  • 94
    • 85005950727 scopus 로고    scopus 로고
    • Hydrogen sulfide concentrations in the heart following acute administration: Methodological and physiological conciderations
    • Sonobe, T.; Haouzi, P. Hydrogen sulfide concentrations in the heart following acute administration: Methodological and physiological conciderations. Am. J. Physiol. Heart Circ. Physiol. 2016.
    • (2016) Am. J. Physiol. Heart Circ. Physiol.
    • Sonobe, T.1    Haouzi, P.2
  • 95
    • 84903216942 scopus 로고    scopus 로고
    • Exogenous hydrogen sulfide causes different hemodynamic effects in normotensive and hypertensive rats via neurogenic mechanisms
    • Sikora, M.; Drapala, A.; Ufnal, M. Exogenous hydrogen sulfide causes different hemodynamic effects in normotensive and hypertensive rats via neurogenic mechanisms. Pharmacol. Rep. 2014, 66, 751-758.
    • (2014) Pharmacol. Rep. , vol.66 , pp. 751-758
    • Sikora, M.1    Drapala, A.2    Ufnal, M.3
  • 96
    • 84860736030 scopus 로고    scopus 로고
    • Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications
    • Szabo, C. Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications. Antioxid. Redox Signal. 2012, 17, 68-80.
    • (2012) Antioxid. Redox Signal. , vol.17 , pp. 68-80
    • Szabo, C.1
  • 97
    • 84929031571 scopus 로고    scopus 로고
    • Hydrogen sulfide-based therapeutics: Exploiting a unique but ubiquitous gasotransmitter
    • Wallace, J.L.; Wang, R. Hydrogen sulfide-based therapeutics: Exploiting a unique but ubiquitous gasotransmitter. Nat. Rev. Drug Discov. 2015, 14, 329-345.
    • (2015) Nat. Rev. Drug Discov. , vol.14 , pp. 329-345
    • Wallace, J.L.1    Wang, R.2
  • 101
    • 0032004697 scopus 로고    scopus 로고
    • Nonenzymatic nitric oxide production in humans
    • Weitzberg, E.; Lundberg, J.O.N. Nonenzymatic nitric oxide production in humans. Nitric Oxide 1998, 2, 1-7.
    • (1998) Nitric Oxide , vol.2 , pp. 1-7
    • Weitzberg, E.1    Lundberg, J.O.N.2
  • 105
    • 14644429695 scopus 로고    scopus 로고
    • A flavo-diiron protein from Desulfovibrio vulgaris with oxidase and nitric oxide reductase activities. Evidence for an in vivo nitric oxide scavenging function
    • Silaghi-Dumitrescu, R.; Kim, Y.N.; Viswanathan, R.; Kurtz, D.M., Jr. A flavo-diiron protein from Desulfovibrio vulgaris with oxidase and nitric oxide reductase activities. Evidence for an in vivo nitric oxide scavenging function. Biochemistry 2005, 44, 3572-3579.
    • (2005) Biochemistry , vol.44 , pp. 3572-3579
    • Silaghi-Dumitrescu, R.1    Kim, Y.N.2    Viswanathan, R.3    Kurtz, D.M.4
  • 107
    • 79952243171 scopus 로고    scopus 로고
    • Nitric oxide physiology and pathology
    • Hirst, D.G.; Robson, T. Nitric oxide physiology and pathology. Methods Mol. Biol. 2011, 704, 1-13.
    • (2011) Methods Mol. Biol. , vol.704 , pp. 1-13
    • Hirst, D.G.1    Robson, T.2
  • 108
    • 84874662091 scopus 로고    scopus 로고
    • Biology of nitrogen oxides in the gastrointestinal tract
    • Lundberg, J.O.; Weitzberg, E. Biology of nitrogen oxides in the gastrointestinal tract. Gut 2013, 62, 616-629.
    • (2013) Gut , vol.62 , pp. 616-629
    • Lundberg, J.O.1    Weitzberg, E.2
  • 109
    • 84904691234 scopus 로고    scopus 로고
    • Carbon monoxide, hydrogen sulfide, and nitric oxide as signaling molecules in the gastrointestinal tract
    • Farrugia, G.; Szurszewski, J.H. Carbon monoxide, hydrogen sulfide, and nitric oxide as signaling molecules in the gastrointestinal tract. Gastroenterology 2014, 147, 303-313.
    • (2014) Gastroenterology , vol.147 , pp. 303-313
    • Farrugia, G.1    Szurszewski, J.H.2
  • 110
    • 84978759658 scopus 로고    scopus 로고
    • Nitric oxide and the cardiovascular system
    • Bohlen, H.G. Nitric oxide and the cardiovascular system. Compr. Physiol. 2015, 5, 803-828.
    • (2015) Compr. Physiol. , vol.5 , pp. 803-828
    • Bohlen, H.G.1
  • 111
    • 84887206478 scopus 로고    scopus 로고
    • Nitric oxide, a protective molecule in the cardiovascular system
    • Lei, J.; Vodovotz, Y.; Tzeng, E.; Billiar, T.R. Nitric oxide, a protective molecule in the cardiovascular system. Nitric Oxide 2013, 35, 175-185.
    • (2013) Nitric Oxide , vol.35 , pp. 175-185
    • Lei, J.1    Vodovotz, Y.2    Tzeng, E.3    Billiar, T.R.4
  • 112
    • 79951602338 scopus 로고    scopus 로고
    • Nitric oxide and the cardiovascular system: Cell activation, vascular reactivity and genetic variant
    • Dias, R.G.; Negrão, C.E.; Krieger, M.H. Nitric oxide and the cardiovascular system: Cell activation, vascular reactivity and genetic variant. Arq. Bras. Cardiol. 2011, 96, 68-75.
    • (2011) Arq. Bras. Cardiol. , vol.96 , pp. 68-75
    • Dias, R.G.1    Negrão, C.E.2    Krieger, M.H.3
  • 114
    • 0036770255 scopus 로고    scopus 로고
    • The nitric oxide pathway in the cardiovascular system
    • Llorens, S.; Jordán, J.; Nava, E. The nitric oxide pathway in the cardiovascular system. J. Physiol. Biochem. 2002, 58, 179-188.
    • (2002) J. Physiol. Biochem. , vol.58 , pp. 179-188
    • Llorens, S.1    Jordán, J.2    Nava, E.3
  • 115
    • 84969579996 scopus 로고    scopus 로고
    • Microbiota and the nitrogen cycle: Implications in the development and progression of CVD and CKD
    • Briskey, D.; Tucker, P.S.; Johnson, D.W.; Coombes, J.S. Microbiota and the nitrogen cycle: Implications in the development and progression of CVD and CKD. Nitric Oxide 2016, 57, 64-70.
    • (2016) Nitric Oxide , vol.57 , pp. 64-70
    • Briskey, D.1    Tucker, P.S.2    Johnson, D.W.3    Coombes, J.S.4
  • 116
    • 84925605686 scopus 로고    scopus 로고
    • Nitrate reduction to nitrite, nitric oxide and ammonia by gut bacteria under physiological conditions
    • Tiso, M.; Schechter, A.N. Nitrate reduction to nitrite, nitric oxide and ammonia by gut bacteria under physiological conditions. PLoS ONE 2015, 10, e0119712.
    • (2015) PLoS ONE , vol.10
    • Tiso, M.1    Schechter, A.N.2
  • 117
    • 0036135781 scopus 로고    scopus 로고
    • Ammonia- and nitrite-oxidizing bacterial communities in a pilot-scale chloraminated drinking water distribution system
    • Regan, J.M.; Harrington, G.W.; Noguera, D.R. Ammonia- and nitrite-oxidizing bacterial communities in a pilot-scale chloraminated drinking water distribution system. Appl. Environ. Microbiol. 2002, 68, 73-81.
    • (2002) Appl. Environ. Microbiol. , vol.68 , pp. 73-81
    • Regan, J.M.1    Harrington, G.W.2    Noguera, D.R.3
  • 119
    • 84937467873 scopus 로고    scopus 로고
    • Clinical and prognostic role of ammonia in advanced decompensated heart failure the cardio-abdominal syndrome?
    • Frea, S.; Bovolo, V.; Pidello, S.; Canavosio, F.G.; Botta, M.; Bergerone, S.; Gaita, F. Clinical and prognostic role of ammonia in advanced decompensated heart failure the cardio-abdominal syndrome? Int. J. Cardiol. 2015, 195, 53-60.
    • (2015) Int. J. Cardiol. , vol.195 , pp. 53-60
    • Frea, S.1    Bovolo, V.2    Pidello, S.3    Canavosio, F.G.4    Botta, M.5    Bergerone, S.6    Gaita, F.7
  • 120
    • 84893438378 scopus 로고    scopus 로고
    • The dysfunction of ammonia in heart failure increases with an increase in the intensity of resistance exercise, even with the use of appropriate drug therapy
    • Medeiros, W.M.; Carvalho, A.C.; Peres, P.; De Luca, F.A.; Gun, C. The dysfunction of ammonia in heart failure increases with an increase in the intensity of resistance exercise, even with the use of appropriate drug therapy. Eur. J. Prev. Cardiol. 2014, 21, 135-144.
    • (2014) Eur. J. Prev. Cardiol. , vol.21 , pp. 135-144
    • Medeiros, W.M.1    Carvalho, A.C.2    Peres, P.3    De Luca, F.A.4    Gun, C.5
  • 121
    • 84903545914 scopus 로고    scopus 로고
    • The history of aerobic ammonia oxidizers: From the first discoveries to today
    • Monteiro, M.; Séneca, J.; Magalhães, C. The history of aerobic ammonia oxidizers: From the first discoveries to today. J. Microbiol. 2014, 52, 537-547.
    • (2014) J. Microbiol. , vol.52 , pp. 537-547
    • Monteiro, M.1    Séneca, J.2    Magalhães, C.3
  • 122
    • 5444228527 scopus 로고    scopus 로고
    • Heme oxygenase and carbon monoxide in the physiology and pathology of the cardiovascular system
    • Bełtowski, J.; Jamroz, A.; Borkowska, E. Heme oxygenase and carbon monoxide in the physiology and pathology of the cardiovascular system. Postepy. Hig. Med. Dosw. 2004, 58, 83-99.
    • (2004) Postepy. Hig. Med. Dosw. , vol.58 , pp. 83-99
    • Bełtowski, J.1    Jamroz, A.2    Borkowska, E.3
  • 123
    • 33845303988 scopus 로고    scopus 로고
    • Role of carbon monoxide in cardiovascular function
    • Durante, W.; Johnson, F.K.; Johnson, R.A. Role of carbon monoxide in cardiovascular function. J. Cell. Mol. Med. 2006, 10, 672-686.
    • (2006) J. Cell. Mol. Med. , vol.10 , pp. 672-686
    • Durante, W.1    Johnson, F.K.2    Johnson, R.A.3
  • 126
    • 0033867966 scopus 로고    scopus 로고
    • Phylogenetic, and ecological diversity of methanogenic Archaea
    • Garcia, J.L.; Patel, B.K.C.; Ollivier, B. Taxonomic, phylogenetic, and ecological diversity of methanogenic Archaea. Anaerobe 2000, 6, 205-226.
    • (2000) Anaerobe , vol.6 , pp. 205-226
    • Garcia, J.L.1    Patel, B.K.C.2    Ollivier, B.T.3
  • 127
    • 41349083576 scopus 로고    scopus 로고
    • Metabolic, phylogenetic, and ecological diversity of the methanogenic archaea
    • Liu, Y.; Whitman, W.B. Metabolic, phylogenetic, and ecological diversity of the methanogenic archaea. Ann. N. Y. Acad. Sci. 2008, 1125, 171-189.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1125 , pp. 171-189
    • Liu, Y.1    Whitman, W.B.2
  • 128
    • 0033005876 scopus 로고    scopus 로고
    • Enzymology of one-carbon metabolism in methanogenic pathways
    • Ferry, J.G. Enzymology of one-carbon metabolism in methanogenic pathways. FEMS Microbiol. Rev. 1999, 23, 13-38.
    • (1999) FEMS Microbiol. Rev. , vol.23 , pp. 13-38
    • Ferry, J.G.1
  • 131
    • 0026806723 scopus 로고
    • Role of dietary sulphate in the regulation of methanogenesis in the human large intestine
    • Christl, S.U.; Gibson, G.R.; Cummings, J.H. Role of dietary sulphate in the regulation of methanogenesis in the human large intestine. Gut 1992, 33, 1234-1238.
    • (1992) Gut , vol.33 , pp. 1234-1238
    • Christl, S.U.1    Gibson, G.R.2    Cummings, J.H.3
  • 133
    • 84924366080 scopus 로고    scopus 로고
    • The role of methane in mammalian physiology-Is it a gasotransmitter?
    • Boros, M.; Tuboly, E.; Mészáros, A.; Amann, A. The role of methane in mammalian physiology-Is it a gasotransmitter? J. Breath Res. 2015, 9, 014001.
    • (2015) J. Breath Res. , vol.9
    • Boros, M.1    Tuboly, E.2    Mészáros, A.3    Amann, A.4
  • 134
    • 32044475197 scopus 로고    scopus 로고
    • Stability of human methanogenic flora over 35 years and a review of insights obtained from breath methane measurements
    • Levitt, M.D.; Furne, J.K.; Kuskowski, M.; Ruddy, J. Stability of human methanogenic flora over 35 years and a review of insights obtained from breath methane measurements. Clin. Gastroenterol. Hepatol. 2006, 4, 123-129.
    • (2006) Clin. Gastroenterol. Hepatol. , vol.4 , pp. 123-129
    • Levitt, M.D.1    Furne, J.K.2    Kuskowski, M.3    Ruddy, J.4
  • 135
    • 0021988294 scopus 로고
    • Methane excretion in man-A study of breath, flatus, and faeces
    • McKay, L.F.; Eastwood, M.A.; Brydon, W.G. Methane excretion in man-A study of breath, flatus, and faeces. Gut 1985, 26, 69-74.
    • (1985) Gut , vol.26 , pp. 69-74
    • McKay, L.F.1    Eastwood, M.A.2    Brydon, W.G.3
  • 137
    • 41849111638 scopus 로고    scopus 로고
    • Lactulose breath testing does not discriminate patients with irritable bowel syndrome from healthy controls
    • Bratten, J.R.; Spanier, J.; Jones, M.P. Lactulose breath testing does not discriminate patients with irritable bowel syndrome from healthy controls. Am. J. Gastroenterol. 2008, 103, 958-963.
    • (2008) Am. J. Gastroenterol. , vol.103 , pp. 958-963
    • Bratten, J.R.1    Spanier, J.2    Jones, M.P.3
  • 138
    • 84877024737 scopus 로고    scopus 로고
    • Breath methane positivity is more common and higher in patients with objectively proven delayed transit constipation
    • Lee, K.M.; Paik, C.N.; Chung, W.C.; Yang, J.M.; Choi, M.G. Breath methane positivity is more common and higher in patients with objectively proven delayed transit constipation. Eur. J. Gastroenterol. Hepatol. 2013, 25, 726-732.
    • (2013) Eur. J. Gastroenterol. Hepatol. , vol.25 , pp. 726-732
    • Lee, K.M.1    Paik, C.N.2    Chung, W.C.3    Yang, J.M.4    Choi, M.G.5
  • 140
    • 84855936051 scopus 로고    scopus 로고
    • The effects of methane and hydrogen gases produced by enteric bacteria on ileal motility and colonic transit time
    • Jahng, J.; Jung, I.S.; Choi, E.J.; Conklin, J.L.; Park, H. The effects of methane and hydrogen gases produced by enteric bacteria on ileal motility and colonic transit time. Neurogastroenterol. Motil. 2012, 24, 185-192.
    • (2012) Neurogastroenterol. Motil. , vol.24 , pp. 185-192
    • Jahng, J.1    Jung, I.S.2    Choi, E.J.3    Conklin, J.L.4    Park, H.5
  • 141
    • 0842269966 scopus 로고    scopus 로고
    • IBS Subjects with Methane on Lactulose Breath Test Have Lower Postprandial Serotonin Levels Than Subjects with Hydrogen
    • Pimentel, M.; Kong, Y.; Park, S. IBS Subjects with Methane on Lactulose Breath Test Have Lower Postprandial Serotonin Levels Than Subjects with Hydrogen. Dig. Dis. Sci. 2004, 49, 84-87.
    • (2004) Dig. Dis. Sci. , vol.49 , pp. 84-87
    • Pimentel, M.1    Kong, Y.2    Park, S.3
  • 142
    • 84875308891 scopus 로고    scopus 로고
    • Effects of methane on proximal colon motility of rats and ion channel mechanisms
    • Liu, Y.; Luo, H.S.; Liang, C.B.; Tan, W.; Xia, H.; Xu, W.J. Effects of methane on proximal colon motility of rats and ion channel mechanisms. Zhonghua Yi Xue Za Zhi 2013, 93, 459-463.
    • (2013) Zhonghua Yi Xue Za Zhi , vol.93 , pp. 459-463
    • Liu, Y.1    Luo, H.S.2    Liang, C.B.3    Tan, W.4    Xia, H.5    Xu, W.J.6
  • 144
    • 84876253206 scopus 로고    scopus 로고
    • Methane and hydrogen positivity on breath test is associated with greater body mass index and body fat
    • Mathur, R.; Amichai, M.; Chua, K.S.; Mirocha, J.; Barlow, G.M.; Pimentel, M. Methane and hydrogen positivity on breath test is associated with greater body mass index and body fat. J. Clin. Endocrinol. Metab. 2013, 98, E698-E702.
    • (2013) J. Clin. Endocrinol. Metab. , vol.98 , pp. E698-E702
    • Mathur, R.1    Amichai, M.2    Chua, K.S.3    Mirocha, J.4    Barlow, G.M.5    Pimentel, M.6
  • 145
    • 84930004775 scopus 로고    scopus 로고
    • Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide
    • Romano, K.A.; Vivas, E.I.; Amador-Noguez, D.; Rey, F.E. Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide. mBio 2015, 6, e02481.
    • (2015) mBio , vol.6
    • Romano, K.A.1    Vivas, E.I.2    Amador-Noguez, D.3    Rey, F.E.4
  • 147
    • 84919718375 scopus 로고    scopus 로고
    • Trimethylamine-N-oxide: A carnitine-derived metabolite that prolongs the hypertensive effect of angiotensin II in rats
    • Ufnal, M.; Jazwiec, R.; Dadlez, M.; Drapala, A.; Sikora, M.; Skrzypecki, J. Trimethylamine-N-oxide: A carnitine-derived metabolite that prolongs the hypertensive effect of angiotensin II in rats. Can. J. Cardiol. 2014, 30, 1700-1705.
    • (2014) Can. J. Cardiol. , vol.30 , pp. 1700-1705
    • Ufnal, M.1    Jazwiec, R.2    Dadlez, M.3    Drapala, A.4    Sikora, M.5    Skrzypecki, J.6
  • 149
    • 77953206694 scopus 로고    scopus 로고
    • Indole as an intercellular signal in microbial communities
    • Lee, J.H.; Lee, J. Indole as an intercellular signal in microbial communities. FEMS Microbiol. Rev. 2010, 34, 426-444.
    • (2010) FEMS Microbiol. Rev. , vol.34 , pp. 426-444
    • Lee, J.H.1    Lee, J.2
  • 150
    • 0014504162 scopus 로고
    • Tryptophanase in diverse bacterial species
    • DeMoss, R.D.; Moser, K. Tryptophanase in diverse bacterial species. J. Bacteriol. 1969, 98, 167-171.
    • (1969) J. Bacteriol. , vol.98 , pp. 167-171
    • DeMoss, R.D.1    Moser, K.2
  • 151
    • 0030888455 scopus 로고    scopus 로고
    • Formation of phenolic and indolic compounds by anaerobic bacteria in the human large intestine
    • Smith, E.A.; Macfarlane, G.T. Formation of phenolic and indolic compounds by anaerobic bacteria in the human large intestine. Microbial. Ecol. 1997, 33, 180-188.
    • (1997) Microbial. Ecol. , vol.33 , pp. 180-188
    • Smith, E.A.1    Macfarlane, G.T.2
  • 152
    • 84946058850 scopus 로고    scopus 로고
    • A rapid and specific method for the detection of indole in complex biological samples
    • Darkoh, C.; Chappell, C.; Gonzales, C.; Okhuysen, P. A rapid and specific method for the detection of indole in complex biological samples. Appl. Environ. Microbiol. 2015, 81, 8093-8097.
    • (2015) Appl. Environ. Microbiol. , vol.81 , pp. 8093-8097
    • Darkoh, C.1    Chappell, C.2    Gonzales, C.3    Okhuysen, P.4
  • 153
    • 84932614326 scopus 로고    scopus 로고
    • Indole: A signaling molecule or a mere metabolic byproduct that alters bacterial physiology at a high concentration?
    • Kim, J.; Park, W. Indole: A signaling molecule or a mere metabolic byproduct that alters bacterial physiology at a high concentration? J. Microbiol. 2015, 53, 421-428.
    • (2015) J. Microbiol. , vol.53 , pp. 421-428
    • Kim, J.1    Park, W.2
  • 154
    • 58249098422 scopus 로고    scopus 로고
    • Serum indoxyl sulfate levels in patients with diabetic nephropathy: Relation to renal function
    • Atoh, K.; Itoh, H.; Haneda, M. Serum indoxyl sulfate levels in patients with diabetic nephropathy: Relation to renal function. Diabetes Res. Clin. Pract. 2009, 83, 220-226.
    • (2009) Diabetes Res. Clin. Pract. , vol.83 , pp. 220-226
    • Atoh, K.1    Itoh, H.2    Haneda, M.3
  • 155
    • 84908236178 scopus 로고    scopus 로고
    • Plasma Indoxyl sulfate and estimated Glomerular filtration rate-Association with long-term clinical outcome in patients with coronary artery disease
    • Yoshikawa, D.; Ishii, H.; Suzuki, S.; Takeshita, K.; Kumagai, S.; Hayashi, M.; Niwa, T.; Izawa, H.; Murohara, T. Plasma Indoxyl sulfate and estimated Glomerular filtration rate-Association with long-term clinical outcome in patients with coronary artery disease. Circ. J. 2014, 78, 2477-2482.
    • (2014) Circ. J. , vol.78 , pp. 2477-2482
    • Yoshikawa, D.1    Ishii, H.2    Suzuki, S.3    Takeshita, K.4    Kumagai, S.5    Hayashi, M.6    Niwa, T.7    Izawa, H.8    Murohara, T.9
  • 158
    • 84864044989 scopus 로고    scopus 로고
    • Chronic kidney disease-induced cardiac fibrosis is ameliorated by reducing circulating levels of a non-dialysable uremic toxin, indoxyl sulfate
    • Lekawanvijit, S.; Kompa, A.R.; Manabe, M.; Wang, B.H.; Langham, R.G.; Nishijima, F.; Kelly, D.J.; Krum, H. Chronic kidney disease-induced cardiac fibrosis is ameliorated by reducing circulating levels of a non-dialysable uremic toxin, indoxyl sulfate. PLoS ONE 2012, 7, e41281.
    • (2012) PLoS ONE , vol.7
    • Lekawanvijit, S.1    Kompa, A.R.2    Manabe, M.3    Wang, B.H.4    Langham, R.G.5    Nishijima, F.6    Kelly, D.J.7    Krum, H.8
  • 159
    • 0033762864 scopus 로고    scopus 로고
    • An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-β1 in uraemic rat kidneys
    • Miyazaki, T.; Aoyama, I.; Ise, M.; Seo, H.; Niwa, T. An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-β1 in uraemic rat kidneys. Nephrol. Dial. Transplant. 2000, 15, 1773-1781.
    • (2000) Nephrol. Dial. Transplant. , vol.15 , pp. 1773-1781
    • Miyazaki, T.1    Aoyama, I.2    Ise, M.3    Seo, H.4    Niwa, T.5
  • 160
    • 77954786480 scopus 로고    scopus 로고
    • Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?
    • Lekawanvijit, S.; Adrahtas, A.; Kelly, D.J.; Kompa, A.R.; Wang, B.H.; Krum, H. Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes? Eur. Heart J. 2010, 31, 1771-1779.
    • (2010) Eur. Heart J. , vol.31 , pp. 1771-1779
    • Lekawanvijit, S.1    Adrahtas, A.2    Kelly, D.J.3    Kompa, A.R.4    Wang, B.H.5    Krum, H.6
  • 161
    • 76249101130 scopus 로고    scopus 로고
    • The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation
    • Bansal, T.; Alaniz, R.C.; Wood, T.K.; Jayaraman, A. The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation. Proc. Natl. Acad. Sci. USA 2010, 107, 228-233.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 228-233
    • Bansal, T.1    Alaniz, R.C.2    Wood, T.K.3    Jayaraman, A.4
  • 163
    • 84872132467 scopus 로고    scopus 로고
    • Ammonia production by human faecal bacteria, and the enumeration, isolation and characterization of bacteria capable of growth on peptides and amino acids
    • Richardson, A.J.; McKain, N.; Wallace, R.J. Ammonia production by human faecal bacteria, and the enumeration, isolation and characterization of bacteria capable of growth on peptides and amino acids. BMC Microbiol. 2013, 13.
    • (2013) BMC Microbiol. , vol.13
    • Richardson, A.J.1    McKain, N.2    Wallace, R.J.3
  • 164
    • 82055206611 scopus 로고    scopus 로고
    • The inotropic effects of ammonia on isolated perfused rat hearts and the mechanisms involved
    • Zhang, Q.; Meng, Z. The inotropic effects of ammonia on isolated perfused rat hearts and the mechanisms involved. J. Exp. Biol. 2011, 214, 4048-4054.
    • (2011) J. Exp. Biol. , vol.214 , pp. 4048-4054
    • Zhang, Q.1    Meng, Z.2
  • 165
    • 84958059755 scopus 로고    scopus 로고
    • Cerebrovascular, cardiovascular and strength responses to acute ammonia inhalation
    • Perry, B.G.; Pritchard, H.J.; Barnes, M.J. Cerebrovascular, cardiovascular and strength responses to acute ammonia inhalation. Eur. J. Appl. Physiol. 2016, 116, 583-592.
    • (2016) Eur. J. Appl. Physiol. , vol.116 , pp. 583-592
    • Perry, B.G.1    Pritchard, H.J.2    Barnes, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.