-
1
-
-
0037448912
-
Trimethylamine N-oxide stabilizes RNA tertiary structure and attenuates the denaturating effects of urea
-
Gluick T.C., Yadav S. Trimethylamine N-oxide stabilizes RNA tertiary structure and attenuates the denaturating effects of urea. J Am Chem Soc 2003, 125:4418-4419.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 4418-4419
-
-
Gluick, T.C.1
Yadav, S.2
-
2
-
-
84902134138
-
Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO)
-
Ma J., Pazos I.M., Gai F. Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO). Proc Natl Acad Sci U S A 2014, 111:8476-8481.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 8476-8481
-
-
Ma, J.1
Pazos, I.M.2
Gai, F.3
-
3
-
-
58049184362
-
Effect of osmolytes on pressure-induced unfolding of proteins: a high-pressure SAXS study
-
Krywka C., Sternemann C., Paulus M., Tolan M., Royer C., Winter R. Effect of osmolytes on pressure-induced unfolding of proteins: a high-pressure SAXS study. Chemphyschem 2008, 9:2809-2815.
-
(2008)
Chemphyschem
, vol.9
, pp. 2809-2815
-
-
Krywka, C.1
Sternemann, C.2
Paulus, M.3
Tolan, M.4
Royer, C.5
Winter, R.6
-
4
-
-
84880797580
-
When does trimethylamine N-oxide fold a polymer chain and urea unfold it?
-
Mondal J., Stirnemann G., Berne B.J. When does trimethylamine N-oxide fold a polymer chain and urea unfold it?. J Phys Chem B 2013, 117:8723-8732.
-
(2013)
J Phys Chem B
, vol.117
, pp. 8723-8732
-
-
Mondal, J.1
Stirnemann, G.2
Berne, B.J.3
-
5
-
-
84877719158
-
Exploring the molecular mechanism of trimethylamine-N-oxide's ability to counteract the protein denaturing effects of urea
-
Sarma R., Paul S. Exploring the molecular mechanism of trimethylamine-N-oxide's ability to counteract the protein denaturing effects of urea. J Phys Chem B 2013, 117:5691-5704.
-
(2013)
J Phys Chem B
, vol.117
, pp. 5691-5704
-
-
Sarma, R.1
Paul, S.2
-
6
-
-
2342614722
-
Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution
-
Bennion B.J., Daggett V. Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution. Proc Natl Acad Sci U S A 2004, 101:6433-6438.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 6433-6438
-
-
Bennion, B.J.1
Daggett, V.2
-
7
-
-
0035104083
-
Water structure changes induced by hydrophobic and polar solutes revealed by simulations and infrared spectroscopy
-
Sharp K.A., Madan B., Manas E., Vanderkooi J.M. Water structure changes induced by hydrophobic and polar solutes revealed by simulations and infrared spectroscopy. J Chem Phys 2001, 114:1791-1796.
-
(2001)
J Chem Phys
, vol.114
, pp. 1791-1796
-
-
Sharp, K.A.1
Madan, B.2
Manas, E.3
Vanderkooi, J.M.4
-
8
-
-
23244459863
-
Osmolyte trimethylamine-N-oxide does not affect the strength of hydrophobic interactions: origin of osmolyte compatibility
-
Athawale M.V., Dordick J.S., Garde S. Osmolyte trimethylamine-N-oxide does not affect the strength of hydrophobic interactions: origin of osmolyte compatibility. Biophys J 2005, 89:858-866.
-
(2005)
Biophys J
, vol.89
, pp. 858-866
-
-
Athawale, M.V.1
Dordick, J.S.2
Garde, S.3
-
9
-
-
80855139861
-
Entropic stabilization of proteins by TMAO
-
Cho S.S., Reddy G., Straub J.E., Thirumalai D. Entropic stabilization of proteins by TMAO. J Phys Chem B 2011, 115:13401-13407.
-
(2011)
J Phys Chem B
, vol.115
, pp. 13401-13407
-
-
Cho, S.S.1
Reddy, G.2
Straub, J.E.3
Thirumalai, D.4
-
10
-
-
34247121912
-
Structure and interaction in aqueous urea-trimethylamine-N-oxide solutions
-
Paul S., Patey G.N. Structure and interaction in aqueous urea-trimethylamine-N-oxide solutions. J Am Chem Soc 2007, 129:4476-4482.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 4476-4482
-
-
Paul, S.1
Patey, G.N.2
-
11
-
-
79951529371
-
Peptide conformational preferences in osmolyte solutions: transfer free energies of decaalanine
-
Kokubo H., Hu C.Y., Pettitt B.M. Peptide conformational preferences in osmolyte solutions: transfer free energies of decaalanine. J Am Chem Soc 2011, 133:1849-1858.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 1849-1858
-
-
Kokubo, H.1
Hu, C.Y.2
Pettitt, B.M.3
-
12
-
-
74949083228
-
Effects of cosolvents on the hydration of carbon nanotubes
-
Yang L., Gao Y.Q. Effects of cosolvents on the hydration of carbon nanotubes. J Am Chem Soc 2010, 132:842-848.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 842-848
-
-
Yang, L.1
Gao, Y.Q.2
-
13
-
-
33846521172
-
Mixed osmolytes: the degree to which one osmolyte affects the protein stabilizing ability of another
-
Holthauzen L.M.F., Bolen D.W. Mixed osmolytes: the degree to which one osmolyte affects the protein stabilizing ability of another. Protein Sci 2007, 16:293-298.
-
(2007)
Protein Sci
, vol.16
, pp. 293-298
-
-
Holthauzen, L.M.F.1
Bolen, D.W.2
-
14
-
-
33749365298
-
A molecular mechanism for osmolyte-induced protein stability
-
Street T.O., Bolen D.W., Rose G.D. A molecular mechanism for osmolyte-induced protein stability. Proc Natl Acad Sci U S A 2006, 103:13997-14002.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 13997-14002
-
-
Street, T.O.1
Bolen, D.W.2
Rose, G.D.3
-
15
-
-
77949878597
-
Trimethylamine N-oxide influence on the backbone of proteins: an oligoglycine model
-
Hu C.Y., Lynch G.C., Kokubo H., Pettitt B.M. Trimethylamine N-oxide influence on the backbone of proteins: an oligoglycine model. Proteins 2010, 78:695-704.
-
(2010)
Proteins
, vol.78
, pp. 695-704
-
-
Hu, C.Y.1
Lynch, G.C.2
Kokubo, H.3
Pettitt, B.M.4
-
16
-
-
0035958656
-
The osmophobic effect: natural selection of a thermodynamic force in protein folding
-
Bolen D., Baskakov I.V. The osmophobic effect: natural selection of a thermodynamic force in protein folding. J Mol Biol 2001, 310:955-963.
-
(2001)
J Mol Biol
, vol.310
, pp. 955-963
-
-
Bolen, D.1
Baskakov, I.V.2
-
17
-
-
84868097108
-
Molecular mechanism for the preferential exclusion of TMAO from protein surfaces
-
Canchi D.R., Jayasimha P., Rau D.C., Makhatadze G.I., Garcia A.E. Molecular mechanism for the preferential exclusion of TMAO from protein surfaces. J Phys Chem B 2012, 116:12095-12104.
-
(2012)
J Phys Chem B
, vol.116
, pp. 12095-12104
-
-
Canchi, D.R.1
Jayasimha, P.2
Rau, D.C.3
Makhatadze, G.I.4
Garcia, A.E.5
-
18
-
-
23044529588
-
Water stress, osmolytes and proteins
-
Yancey P.H. Water stress, osmolytes and proteins. Am Zool 2001, 41:699-709.
-
(2001)
Am Zool
, vol.41
, pp. 699-709
-
-
Yancey, P.H.1
-
19
-
-
84893533045
-
Effects of feeding diets containing increasing proportions of bunt-infected wheat (Tilletia caries) on performance and health of pigs
-
Preugschat K., Kersten S., Ettle T., Richter W., Karl H., Breves G., et al. Effects of feeding diets containing increasing proportions of bunt-infected wheat (Tilletia caries) on performance and health of pigs. Arch Anim Nutr 2014, 68:55-62.
-
(2014)
Arch Anim Nutr
, vol.68
, pp. 55-62
-
-
Preugschat, K.1
Kersten, S.2
Ettle, T.3
Richter, W.4
Karl, H.5
Breves, G.6
-
20
-
-
84942382588
-
Trimethylaminuria
-
GeneReviews(R), Seattle, WA, R.A. Pagon, M.P. Adam, H.H. Ardinger, T.D. Bird, C.R. Dolan, C.T. Fong (Eds.)
-
Phillips I.R., Shephard E.A. Trimethylaminuria. Gene Reviews 1993, GeneReviews(R), Seattle, WA. R.A. Pagon, M.P. Adam, H.H. Ardinger, T.D. Bird, C.R. Dolan, C.T. Fong (Eds.).
-
(1993)
Gene Reviews
-
-
Phillips, I.R.1
Shephard, E.A.2
-
21
-
-
84877331372
-
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis
-
Koeth R.A., Wang Z., Levison B.S., Buffa J.A., Org E., Sheehy B.T., et al. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med 2013, 19:576-585.
-
(2013)
Nat Med
, vol.19
, pp. 576-585
-
-
Koeth, R.A.1
Wang, Z.2
Levison, B.S.3
Buffa, J.A.4
Org, E.5
Sheehy, B.T.6
-
22
-
-
0015338999
-
Biosynthesis of trimethylamine oxide in the nurse shark, Ginglymostoma cirratum
-
Goldstein L., Funkhouser D. Biosynthesis of trimethylamine oxide in the nurse shark, Ginglymostoma cirratum. Comp Biochem Physiol A Comp Physiol 1972, 42:51-57.
-
(1972)
Comp Biochem Physiol A Comp Physiol
, vol.42
, pp. 51-57
-
-
Goldstein, L.1
Funkhouser, D.2
-
23
-
-
0036330578
-
Trimethylamine oxide accumulation in marine animals: relationship to acylglycerol storage
-
Seibel B.A., Walsh P.J. Trimethylamine oxide accumulation in marine animals: relationship to acylglycerol storage. J Exp Biol 2002, 205:297-306.
-
(2002)
J Exp Biol
, vol.205
, pp. 297-306
-
-
Seibel, B.A.1
Walsh, P.J.2
-
24
-
-
24644450812
-
Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses
-
Yancey P.H. Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses. J Exp Biol 2005, 208:2819-2830.
-
(2005)
J Exp Biol
, vol.208
, pp. 2819-2830
-
-
Yancey, P.H.1
-
25
-
-
0020823112
-
Gas chromatographic determination of dimethylamine and trimethylamine in seafoods
-
Lundstrom R.C., Racicot L.D. Gas chromatographic determination of dimethylamine and trimethylamine in seafoods. J Assoc Off Anal Chem 1983, 66:1158-1163.
-
(1983)
J Assoc Off Anal Chem
, vol.66
, pp. 1158-1163
-
-
Lundstrom, R.C.1
Racicot, L.D.2
-
26
-
-
0021778428
-
Bacterial reduction of trimethylamine oxide
-
Barrett E.L., Kwan H.S. Bacterial reduction of trimethylamine oxide. Annu Rev Microbiol 1985, 39:131-149.
-
(1985)
Annu Rev Microbiol
, vol.39
, pp. 131-149
-
-
Barrett, E.L.1
Kwan, H.S.2
-
27
-
-
0026677317
-
Inhibition of the electron transport system in Staphylococcus aureus by trimethylamine-N-oxide
-
Suzuki S., Kubo A., Shinano H., Takama K. Inhibition of the electron transport system in Staphylococcus aureus by trimethylamine-N-oxide. Microbios 1992, 71:145-148.
-
(1992)
Microbios
, vol.71
, pp. 145-148
-
-
Suzuki, S.1
Kubo, A.2
Shinano, H.3
Takama, K.4
-
28
-
-
84894367965
-
Trimethylamine N-oxide metabolism by abundant marine heterotrophic bacteria
-
Lidbury I., Murrell J.C., Chen Y. Trimethylamine N-oxide metabolism by abundant marine heterotrophic bacteria. Proc Natl Acad Sci U S A 2014, 111:2710-2715.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 2710-2715
-
-
Lidbury, I.1
Murrell, J.C.2
Chen, Y.3
-
29
-
-
80055095638
-
Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase
-
Chen Y., Patel N.A., Crombie A., Scrivens J.H., Murrell J.C. Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase. Proc Natl Acad Sci U S A 2011, 108:17791-17796.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 17791-17796
-
-
Chen, Y.1
Patel, N.A.2
Crombie, A.3
Scrivens, J.H.4
Murrell, J.C.5
-
31
-
-
0015022378
-
The formation of nitrosamines by human intestinal bacteria
-
Hawksworth G., Hill M. The formation of nitrosamines by human intestinal bacteria. Biochem J 1971, 122:28P-29P.
-
(1971)
Biochem J
, vol.122
, pp. 28P-29P
-
-
Hawksworth, G.1
Hill, M.2
-
32
-
-
43149110398
-
Intracellular organic osmolytes: Function and regulation
-
Burg M.B., Ferraris J.D. Intracellular organic osmolytes: Function and regulation. J Biol Chem 2008, 283:7309-7313.
-
(2008)
J Biol Chem
, vol.283
, pp. 7309-7313
-
-
Burg, M.B.1
Ferraris, J.D.2
-
33
-
-
0030762556
-
A naturally occurring protective system in urea-rich cells: mechanism of osmolyte protection of proteins against urea denaturation
-
Wang A., Bolen D.W. A naturally occurring protective system in urea-rich cells: mechanism of osmolyte protection of proteins against urea denaturation. Biochemistry 1997, 36:9101-9108.
-
(1997)
Biochemistry
, vol.36
, pp. 9101-9108
-
-
Wang, A.1
Bolen, D.W.2
-
34
-
-
21644468585
-
Trimethylamine oxide, betaine and other osmolytes in deep-sea animals: depth trends and effects on enzymes under hydrostatic pressure
-
Yancey P.H., Rhea M.D., Kemp K.M., Bailey D.M. Trimethylamine oxide, betaine and other osmolytes in deep-sea animals: depth trends and effects on enzymes under hydrostatic pressure. Cell Mol Biol 2004, 50:371-376.
-
(2004)
Cell Mol Biol
, vol.50
, pp. 371-376
-
-
Yancey, P.H.1
Rhea, M.D.2
Kemp, K.M.3
Bailey, D.M.4
-
35
-
-
0024335291
-
Conversion of dietary choline to trimethylamine and dimethylamine in rats: dose-response relationship
-
Zeisel S.H., daCosta K.A., Youssef M., Hensey S. Conversion of dietary choline to trimethylamine and dimethylamine in rats: dose-response relationship. J Nutr 1989, 119:800-804.
-
(1989)
J Nutr
, vol.119
, pp. 800-804
-
-
Zeisel, S.H.1
daCosta, K.A.2
Youssef, M.3
Hensey, S.4
-
36
-
-
84907313170
-
Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study
-
Miller C.A., Corbin K.D., da Costa K.A., Zhang S., Zhao X., Galanko J.A., et al. Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study. Am J Clin Nutr 2014, 100:778-786.
-
(2014)
Am J Clin Nutr
, vol.100
, pp. 778-786
-
-
Miller, C.A.1
Corbin, K.D.2
da Costa, K.A.3
Zhang, S.4
Zhao, X.5
Galanko, J.A.6
-
37
-
-
74949113912
-
Choline: an essential nutrient for public health
-
Zeisel S.H., da Costa K.A. Choline: an essential nutrient for public health. Nutr Rev 2009, 67:615-623.
-
(2009)
Nutr Rev
, vol.67
, pp. 615-623
-
-
Zeisel, S.H.1
da Costa, K.A.2
-
38
-
-
84908502147
-
Egg n-3 fatty acid composition modulates biomarkers of choline metabolism in free-living lacto-ovo-vegetarian women of reproductive age
-
West A.A., Shih Y., Wang W., Oda K., Jaceldo-Siegl K., Sabate J., et al. Egg n-3 fatty acid composition modulates biomarkers of choline metabolism in free-living lacto-ovo-vegetarian women of reproductive age. J Acad Nutr Diet 2014, 114:1594-1600.
-
(2014)
J Acad Nutr Diet
, vol.114
, pp. 1594-1600
-
-
West, A.A.1
Shih, Y.2
Wang, W.3
Oda, K.4
Jaceldo-Siegl, K.5
Sabate, J.6
-
39
-
-
0022530690
-
An in vitro study of choline uptake by intestine from neonatal and adult rats
-
Sheard N.F., Zeisel S.H. An in vitro study of choline uptake by intestine from neonatal and adult rats. Pediatr Res 1986, 20:768-772.
-
(1986)
Pediatr Res
, vol.20
, pp. 768-772
-
-
Sheard, N.F.1
Zeisel, S.H.2
-
40
-
-
0017337253
-
Choline influx across the brush border of guinea pig jejunum
-
Kuczler F.J., Nahrwold D.L., Rose R.C. Choline influx across the brush border of guinea pig jejunum. Acta Biochim Biophys 1977, 465:131-137.
-
(1977)
Acta Biochim Biophys
, vol.465
, pp. 131-137
-
-
Kuczler, F.J.1
Nahrwold, D.L.2
Rose, R.C.3
-
41
-
-
0015098165
-
Intestinal transfer of choline in rat and hamster
-
Sanford P.A., Smyth D.H. Intestinal transfer of choline in rat and hamster. J Physiol 1971, 215:769-788.
-
(1971)
J Physiol
, vol.215
, pp. 769-788
-
-
Sanford, P.A.1
Smyth, D.H.2
-
42
-
-
0022347180
-
Endogenous formation of dimethylamine
-
Zeisel S.H., DaCosta K.A., Fox J.G. Endogenous formation of dimethylamine. Biochem J 1985, 232:403-408.
-
(1985)
Biochem J
, vol.232
, pp. 403-408
-
-
Zeisel, S.H.1
DaCosta, K.A.2
Fox, J.G.3
-
43
-
-
79953733693
-
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
-
Wang Z., Klipfell E., Bennett B.J., Koeth R., Levison B.S., Dugar B., et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 2011, 472:57-63.
-
(2011)
Nature
, vol.472
, pp. 57-63
-
-
Wang, Z.1
Klipfell, E.2
Bennett, B.J.3
Koeth, R.4
Levison, B.S.5
Dugar, B.6
-
44
-
-
84888187402
-
Gut microbiota metabolism of L-carnitine and cardiovascular risk
-
Ussher J.R., Lopaschuk G.D., Arduini A. Gut microbiota metabolism of L-carnitine and cardiovascular risk. Atherosclerosis 2013, 231:456-461.
-
(2013)
Atherosclerosis
, vol.231
, pp. 456-461
-
-
Ussher, J.R.1
Lopaschuk, G.D.2
Arduini, A.3
-
45
-
-
33751414502
-
Genomic structure, alternative maturation and tissue expression of the human BBOX1 gene
-
Rigault C., Le Borgne F., Demarquoy J. Genomic structure, alternative maturation and tissue expression of the human BBOX1 gene. Acta Biochim Biophys 2006, 1761:1469-1481.
-
(2006)
Acta Biochim Biophys
, vol.1761
, pp. 1469-1481
-
-
Rigault, C.1
Le Borgne, F.2
Demarquoy, J.3
-
46
-
-
1042266294
-
Radioisotopic determination of L-carnitine content in foods commonly eaten in Western countries
-
Demarquoy J., Georges B., Rigault C., Royer M.-C., Clairet A., Soty M., et al. Radioisotopic determination of L-carnitine content in foods commonly eaten in Western countries. Food Chem 2004, 86:137-142.
-
(2004)
Food Chem
, vol.86
, pp. 137-142
-
-
Demarquoy, J.1
Georges, B.2
Rigault, C.3
Royer, M.-C.4
Clairet, A.5
Soty, M.6
-
47
-
-
36749093429
-
Changes in L-carnitine content of fish and meat during domestic cooking
-
Rigault C., Mazué F., Bernard A., Demarquoy J., Le Borgne F. Changes in L-carnitine content of fish and meat during domestic cooking. Meat Sci 2008, 78:331-335.
-
(2008)
Meat Sci
, vol.78
, pp. 331-335
-
-
Rigault, C.1
Mazué, F.2
Bernard, A.3
Demarquoy, J.4
Le Borgne, F.5
-
48
-
-
0019759561
-
Dietary choline: biochemistry, physiology, and pharmacology
-
Zeisel S.H. Dietary choline: biochemistry, physiology, and pharmacology. Annu Rev Nutr 1981, 1:95-121.
-
(1981)
Annu Rev Nutr
, vol.1
, pp. 95-121
-
-
Zeisel, S.H.1
-
49
-
-
84876563088
-
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk
-
Tang W.H., Wang Z., Levison B.S., Koeth R.A., Britt E.B., Fu X., et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N Engl J Med 2013, 368:1575-1584.
-
(2013)
N Engl J Med
, vol.368
, pp. 1575-1584
-
-
Tang, W.H.1
Wang, Z.2
Levison, B.S.3
Koeth, R.A.4
Britt, E.B.5
Fu, X.6
-
50
-
-
0028333824
-
Urinary excretion of methylamines in men with varying intake of fish from the Baltic Sea
-
Svensson B.G., Akesson B., Nilsson A., Paulsson K. Urinary excretion of methylamines in men with varying intake of fish from the Baltic Sea. J Toxicol Environ Health 1994, 41:411-420.
-
(1994)
J Toxicol Environ Health
, vol.41
, pp. 411-420
-
-
Svensson, B.G.1
Akesson, B.2
Nilsson, A.3
Paulsson, K.4
-
51
-
-
0026022864
-
Nuclear magnetic resonance studies of blood plasma and urine from subjects with chronic renal failure: identification of trimethylamine-N-oxide
-
Bell J.D., Lee J.A., Lee H.A., Sadler P.J., Wilkie D.R., Woodham R.H. Nuclear magnetic resonance studies of blood plasma and urine from subjects with chronic renal failure: identification of trimethylamine-N-oxide. Acta Biochim Biophys 1991, 1096:101-107.
-
(1991)
Acta Biochim Biophys
, vol.1096
, pp. 101-107
-
-
Bell, J.D.1
Lee, J.A.2
Lee, H.A.3
Sadler, P.J.4
Wilkie, D.R.5
Woodham, R.H.6
-
52
-
-
7944220068
-
Metabonomics, dietary influences and cultural differences: a 1 H NMR-based study of urine samples obtained from healthy British and Swedish subjects
-
Lenz E.M., Bright J., Wilson I.D., Hughes A., Morrisson J., Lindberg H., et al. Metabonomics, dietary influences and cultural differences: a 1 H NMR-based study of urine samples obtained from healthy British and Swedish subjects. J Pharm Biomed Anal 2004, 36:841-849.
-
(2004)
J Pharm Biomed Anal
, vol.36
, pp. 841-849
-
-
Lenz, E.M.1
Bright, J.2
Wilson, I.D.3
Hughes, A.4
Morrisson, J.5
Lindberg, H.6
-
53
-
-
33645671556
-
Assessment of analytical reproducibility of 1 H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP Study
-
Dumas M.E., Maibaum E.C., Teague C., Ueshima H., Zhou B., Lindon J.C., et al. Assessment of analytical reproducibility of 1 H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP Study. Anal Chem 2006, 78:2199-2208.
-
(2006)
Anal Chem
, vol.78
, pp. 2199-2208
-
-
Dumas, M.E.1
Maibaum, E.C.2
Teague, C.3
Ueshima, H.4
Zhou, B.5
Lindon, J.C.6
-
54
-
-
84857672348
-
Assessment of the effect of high or low protein diet on the human urine metabolome as measured by NMR
-
Rasmussen L.G., Winning H., Savorani F., Toft H., Larsen T.M., Dragsted L.O., et al. Assessment of the effect of high or low protein diet on the human urine metabolome as measured by NMR. Nutrients 2012, 4:112-131.
-
(2012)
Nutrients
, vol.4
, pp. 112-131
-
-
Rasmussen, L.G.1
Winning, H.2
Savorani, F.3
Toft, H.4
Larsen, T.M.5
Dragsted, L.O.6
-
55
-
-
19944387962
-
Trimethylamine: metabolic, pharmacokinetic and safety aspects
-
Bain M.A., Fornasini G., Evans A.M. Trimethylamine: metabolic, pharmacokinetic and safety aspects. Curr Drug Metab 2005, 6:227-240.
-
(2005)
Curr Drug Metab
, vol.6
, pp. 227-240
-
-
Bain, M.A.1
Fornasini, G.2
Evans, A.M.3
-
56
-
-
80051781426
-
Trimethylaminuria: causes and diagnosis of a socially distressing condition
-
Mackay R.J., McEntyre C.J., Henderson C., Lever M., George P.M. Trimethylaminuria: causes and diagnosis of a socially distressing condition. Clin Biochem Rev 2011, 32:33-43.
-
(2011)
Clin Biochem Rev
, vol.32
, pp. 33-43
-
-
Mackay, R.J.1
McEntyre, C.J.2
Henderson, C.3
Lever, M.4
George, P.M.5
-
57
-
-
84899701813
-
Analysis of volatile compounds in exhaled breath condensate in patients with severe pulmonary arterial hypertension
-
Mansoor J.K., Schelegle E.S., Davis C.E., Walby W.F., Zhao W., Aksenov A.A., et al. Analysis of volatile compounds in exhaled breath condensate in patients with severe pulmonary arterial hypertension. PloS One 2014, 9:e95331.
-
(2014)
PloS One
, vol.9
, pp. e95331
-
-
Mansoor, J.K.1
Schelegle, E.S.2
Davis, C.E.3
Walby, W.F.4
Zhao, W.5
Aksenov, A.A.6
-
58
-
-
33646205972
-
Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis
-
Bain M.A., Faull R., Fornasini G., Milne R.W., Evans A.M. Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis. Nephrol Dial Transplant 2006, 21:1300-1304.
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 1300-1304
-
-
Bain, M.A.1
Faull, R.2
Fornasini, G.3
Milne, R.W.4
Evans, A.M.5
-
59
-
-
84919718375
-
Trimethylamine-N-oxide: a carnitine-derived metabolite that prolongs the hypertensive effect of angiotensin II in rats
-
Ufnal M., Jazwiec R., Dadlez M., Drapala A., Sikora M., Skrzypecki J. Trimethylamine-N-oxide: a carnitine-derived metabolite that prolongs the hypertensive effect of angiotensin II in rats. Can J Cardiol 2014, 30:1700-1705.
-
(2014)
Can J Cardiol
, vol.30
, pp. 1700-1705
-
-
Ufnal, M.1
Jazwiec, R.2
Dadlez, M.3
Drapala, A.4
Sikora, M.5
Skrzypecki, J.6
-
60
-
-
84898859680
-
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide
-
Wang Z., Tang W.H., Buffa J.A., Fu X., Britt E.B., Koeth R.A., et al. Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide. Eur Heart J 2014, 35:904-910.
-
(2014)
Eur Heart J
, vol.35
, pp. 904-910
-
-
Wang, Z.1
Tang, W.H.2
Buffa, J.A.3
Fu, X.4
Britt, E.B.5
Koeth, R.A.6
-
61
-
-
84929655318
-
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure
-
Troseid M., Ueland T., Hov J.R., Svardal A., Gregersen I., Dahl C.P., et al. Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure. J Intern Med 2015, 277:717-726.
-
(2015)
J Intern Med
, vol.277
, pp. 717-726
-
-
Troseid, M.1
Ueland, T.2
Hov, J.R.3
Svardal, A.4
Gregersen, I.5
Dahl, C.P.6
-
62
-
-
84925519643
-
Oral L-carnitine supplementation increases trimethylamine-N-oxide but reduces markers of vascular injury in hemodialysis patients
-
Fukami K., Yamagishi S., Sakai K., Kaida Y., Yokoro M., Ueda S., et al. Oral L-carnitine supplementation increases trimethylamine-N-oxide but reduces markers of vascular injury in hemodialysis patients. J Cardiovasc Pharmacol 2015, 65:289-295.
-
(2015)
J Cardiovasc Pharmacol
, vol.65
, pp. 289-295
-
-
Fukami, K.1
Yamagishi, S.2
Sakai, K.3
Kaida, Y.4
Yokoro, M.5
Ueda, S.6
-
63
-
-
84874415720
-
Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy
-
Lupachyk S., Watcho P., Stavniichuk R., Shevalye H., Obrosova I.G. Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy. Diabetes 2013, 62:944-952.
-
(2013)
Diabetes
, vol.62
, pp. 944-952
-
-
Lupachyk, S.1
Watcho, P.2
Stavniichuk, R.3
Shevalye, H.4
Obrosova, I.G.5
-
64
-
-
33846301100
-
Effects of chemical chaperones on oxidative stress and detergent-insoluble species formation following conditional expression of amyloid precursor protein carboxy-terminal fragment
-
Woltjer R.L., McMahan W., Milatovic D., Kjerulf J.D., Shie F.S., Rung L.G., et al. Effects of chemical chaperones on oxidative stress and detergent-insoluble species formation following conditional expression of amyloid precursor protein carboxy-terminal fragment. Neurobiol Dis 2007, 25:427-437.
-
(2007)
Neurobiol Dis
, vol.25
, pp. 427-437
-
-
Woltjer, R.L.1
McMahan, W.2
Milatovic, D.3
Kjerulf, J.D.4
Shie, F.S.5
Rung, L.G.6
-
65
-
-
0042316748
-
Trimethylaminuria and a human FMO3 mutation database
-
Hernandez D., Addou S., Lee D., Orengo C., Shephard E.A., Phillips I.R. Trimethylaminuria and a human FMO3 mutation database. Hum Mutat 2003, 22:209-213.
-
(2003)
Hum Mutat
, vol.22
, pp. 209-213
-
-
Hernandez, D.1
Addou, S.2
Lee, D.3
Orengo, C.4
Shephard, E.A.5
Phillips, I.R.6
-
66
-
-
84872497868
-
FMO3 allelic variants in Sicilian and Sardinian populations: trimethylaminuria and absence of fish-like body odor
-
D'Angelo R., Esposito T., Calabro M., Rinaldi C., Robledo R., Varriale B., et al. FMO3 allelic variants in Sicilian and Sardinian populations: trimethylaminuria and absence of fish-like body odor. Gene 2013, 515:410-415.
-
(2013)
Gene
, vol.515
, pp. 410-415
-
-
D'Angelo, R.1
Esposito, T.2
Calabro, M.3
Rinaldi, C.4
Robledo, R.5
Varriale, B.6
-
67
-
-
0034523750
-
Citrate, acetate and renal medullary osmolyte excretion in urine as predictor of renal changes after cold ischaemia and transplantation
-
Hauet T., Baumert H., Gibelin H., Godart C., Carretier M., Eugene M. Citrate, acetate and renal medullary osmolyte excretion in urine as predictor of renal changes after cold ischaemia and transplantation. Clin Chem Lab Med 2000, 38:1093-1098.
-
(2000)
Clin Chem Lab Med
, vol.38
, pp. 1093-1098
-
-
Hauet, T.1
Baumert, H.2
Gibelin, H.3
Godart, C.4
Carretier, M.5
Eugene, M.6
-
68
-
-
3242812714
-
Influence of colloid, preservation medium and trimetazidine on renal medulla injury
-
Doucet C., Dutheil D., Petit I., Zhang K., Eugene M., Touchard G., et al. Influence of colloid, preservation medium and trimetazidine on renal medulla injury. Acta Biochim Biophys 2004, 1673:105-114.
-
(2004)
Acta Biochim Biophys
, vol.1673
, pp. 105-114
-
-
Doucet, C.1
Dutheil, D.2
Petit, I.3
Zhang, K.4
Eugene, M.5
Touchard, G.6
-
69
-
-
84921636319
-
Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet
-
Gao X., Liu X., Xu J., Xue C., Xue Y., Wang Y. Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet. J Biosci Bioeng 2014, 118:476-481.
-
(2014)
J Biosci Bioeng
, vol.118
, pp. 476-481
-
-
Gao, X.1
Liu, X.2
Xu, J.3
Xue, C.4
Xue, Y.5
Wang, Y.6
-
70
-
-
84871240216
-
Serum metabolic variables associated with impaired glucose tolerance induced by high-fat-high-cholesterol diet in Macaca mulatta
-
Li X., Chen Y., Liu J., Yang G., Zhao J., Liao G., et al. Serum metabolic variables associated with impaired glucose tolerance induced by high-fat-high-cholesterol diet in Macaca mulatta. Exp Biol Med (Maywood) 2012, 237:1310-1321.
-
(2012)
Exp Biol Med (Maywood)
, vol.237
, pp. 1310-1321
-
-
Li, X.1
Chen, Y.2
Liu, J.3
Yang, G.4
Zhao, J.5
Liao, G.6
-
71
-
-
84918565300
-
Betaine and trimethylamine-N-oxide as predictors of cardiovascular outcomes show different patterns in diabetes mellitus: an observational study
-
Lever M., George P.M., Slow S., Bellamy D., Young J.M., Ho M., et al. Betaine and trimethylamine-N-oxide as predictors of cardiovascular outcomes show different patterns in diabetes mellitus: an observational study. PloS One 2014, 9:e114969.
-
(2014)
PloS One
, vol.9
, pp. e114969
-
-
Lever, M.1
George, P.M.2
Slow, S.3
Bellamy, D.4
Young, J.M.5
Ho, M.6
-
72
-
-
62749130523
-
Metabonomic study of biochemical changes in the serum of type 2 diabetes mellitus patients after the treatment of metformin hydrochloride
-
Huo T., Cai S., Lu X., Sha Y., Yu M., Li F. Metabonomic study of biochemical changes in the serum of type 2 diabetes mellitus patients after the treatment of metformin hydrochloride. J Pharm Biomed Anal 2009, 49:976-982.
-
(2009)
J Pharm Biomed Anal
, vol.49
, pp. 976-982
-
-
Huo, T.1
Cai, S.2
Lu, X.3
Sha, Y.4
Yu, M.5
Li, F.6
-
73
-
-
84930436272
-
Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period
-
McEntyre C.J., Lever M., Chambers S.T., George P.M., Slow S., Elmslie J.L., et al. Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period. Ann Clin Biochem 2015, 52:352-360.
-
(2015)
Ann Clin Biochem
, vol.52
, pp. 352-360
-
-
McEntyre, C.J.1
Lever, M.2
Chambers, S.T.3
George, P.M.4
Slow, S.5
Elmslie, J.L.6
-
74
-
-
66149100956
-
Metabonomics studies of intact hepatic and renal cortical tissues from diabetic db/db mice using high-resolution magic-angle spinning 1 H NMR spectroscopy
-
Xu J., Zhang J., Cai S., Dong J., Yang J.Y., Chen Z. Metabonomics studies of intact hepatic and renal cortical tissues from diabetic db/db mice using high-resolution magic-angle spinning 1 H NMR spectroscopy. Anal Bioanal Chem 2009, 393:1657-1668.
-
(2009)
Anal Bioanal Chem
, vol.393
, pp. 1657-1668
-
-
Xu, J.1
Zhang, J.2
Cai, S.3
Dong, J.4
Yang, J.Y.5
Chen, Z.6
-
75
-
-
84918532090
-
Plasma choline metabolites and colorectal cancer risk in the Women's Health Initiative Observational Study
-
Bae S., Ulrich C.M., Neuhouser M.L., Malysheva O., Bailey L.B., Xiao L., et al. Plasma choline metabolites and colorectal cancer risk in the Women's Health Initiative Observational Study. Cancer Res 2014, 74:7442-7452.
-
(2014)
Cancer Res
, vol.74
, pp. 7442-7452
-
-
Bae, S.1
Ulrich, C.M.2
Neuhouser, M.L.3
Malysheva, O.4
Bailey, L.B.5
Xiao, L.6
-
76
-
-
77958169142
-
Toxicometabolomics of urinary biomarkers for human gastric cancer in a mouse model
-
Kim K.-B., Yang J.-Y., Kwack S.J., Park K.L., Kim H.S., Ryu D.H., et al. Toxicometabolomics of urinary biomarkers for human gastric cancer in a mouse model. J Toxicol Environ Health A 2010, 73:1420-1430.
-
(2010)
J Toxicol Environ Health A
, vol.73
, pp. 1420-1430
-
-
Kim, K.-B.1
Yang, J.-Y.2
Kwack, S.J.3
Park, K.L.4
Kim, H.S.5
Ryu, D.H.6
-
77
-
-
21444443059
-
Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition
-
Norat T., Bingham S., Ferrari P., Slimani N., Jenab M., Mazuir M., et al. Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition. J Natl Cancer Inst 2005, 97:906-916.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 906-916
-
-
Norat, T.1
Bingham, S.2
Ferrari, P.3
Slimani, N.4
Jenab, M.5
Mazuir, M.6
-
78
-
-
0015420930
-
Nitrosation of tertiary amines and some biologic implications
-
Lijinsky W., Keefer L., Conrad E., Van de Bogart R. Nitrosation of tertiary amines and some biologic implications. J Natl Cancer Inst 1972, 49:1239-1249.
-
(1972)
J Natl Cancer Inst
, vol.49
, pp. 1239-1249
-
-
Lijinsky, W.1
Keefer, L.2
Conrad, E.3
Van de Bogart, R.4
-
79
-
-
0021680014
-
Relevance of nitrosamines to human cancer
-
Bartsch H., Montesano R. Relevance of nitrosamines to human cancer. Carcinogenesis 1984, 5:1381-1393.
-
(1984)
Carcinogenesis
, vol.5
, pp. 1381-1393
-
-
Bartsch, H.1
Montesano, R.2
-
80
-
-
34047187041
-
The effect of haem in red and processed meat on the endogenous formation of N-nitroso compounds in the upper gastrointestinal tract
-
Lunn J.C., Kuhnle G., Mai V., Frankenfeld C., Shuker D.E., Glen R.C., et al. The effect of haem in red and processed meat on the endogenous formation of N-nitroso compounds in the upper gastrointestinal tract. Carcinogenesis 2007, 28:685-690.
-
(2007)
Carcinogenesis
, vol.28
, pp. 685-690
-
-
Lunn, J.C.1
Kuhnle, G.2
Mai, V.3
Frankenfeld, C.4
Shuker, D.E.5
Glen, R.C.6
-
81
-
-
59849118632
-
Rescue of the neuroblastoma mutant of the human nucleoside diphosphate kinase A/nm23-H1 by the natural osmolyte trimethylamine-N-oxide
-
Georgescauld F., Mocan I., Lacombe M.L., Lascu I. Rescue of the neuroblastoma mutant of the human nucleoside diphosphate kinase A/nm23-H1 by the natural osmolyte trimethylamine-N-oxide. FEBS Lett 2009, 583:820-824.
-
(2009)
FEBS Lett
, vol.583
, pp. 820-824
-
-
Georgescauld, F.1
Mocan, I.2
Lacombe, M.L.3
Lascu, I.4
-
82
-
-
84898897439
-
Substrate rescue of DNA polymerase beta containing a catastrophic L22 P mutation
-
Kirby T.W., Derose E.F., Beard W.A., Shock D.D., Wilson S.H., London R.E. Substrate rescue of DNA polymerase beta containing a catastrophic L22 P mutation. Biochemistry 2014, 53:2413-2422.
-
(2014)
Biochemistry
, vol.53
, pp. 2413-2422
-
-
Kirby, T.W.1
Derose, E.F.2
Beard, W.A.3
Shock, D.D.4
Wilson, S.H.5
London, R.E.6
-
83
-
-
0033578356
-
Phosphorylated tau can promote tubulin assembly
-
Tseng H.C., Lu Q., Henderson E., Graves D.J. Phosphorylated tau can promote tubulin assembly. Proc Natl Acad Sci U S A 1999, 96:9503-9508.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 9503-9508
-
-
Tseng, H.C.1
Lu, Q.2
Henderson, E.3
Graves, D.J.4
-
84
-
-
0032578616
-
Natural methylamine osmolytes, trimethylamine N-oxide and betaine, increase tau-induced polymerization of microtubules
-
Tseng H.C., Graves D.J. Natural methylamine osmolytes, trimethylamine N-oxide and betaine, increase tau-induced polymerization of microtubules. Biochem Biophys Res Commun 1998, 250:726-730.
-
(1998)
Biochem Biophys Res Commun
, vol.250
, pp. 726-730
-
-
Tseng, H.C.1
Graves, D.J.2
-
85
-
-
79960296401
-
Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases
-
Chamcheu J.C., Navsaria H., Pihl-Lundin I., Liovic M., Vahlquist A., Torma H. Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases. J Invest Dermatol 2011, 131:1684-1691.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1684-1691
-
-
Chamcheu, J.C.1
Navsaria, H.2
Pihl-Lundin, I.3
Liovic, M.4
Vahlquist, A.5
Torma, H.6
-
86
-
-
84873047697
-
In vitro amyloid aggregate forming ability of TGFBI mutants that cause corneal dystrophies
-
Yam G.H., Wang K., Jhanji V., Choy K.W., Baum L., Pang C.P. In vitro amyloid aggregate forming ability of TGFBI mutants that cause corneal dystrophies. Invest Ophthalmol Vis Sci 2012, 53:5890-5898.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 5890-5898
-
-
Yam, G.H.1
Wang, K.2
Jhanji, V.3
Choy, K.W.4
Baum, L.5
Pang, C.P.6
-
87
-
-
34547881945
-
Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats
-
Mulhern M.L., Madson C.J., Kador P.F., Randazzo J., Shinohara T. Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats. Mol Vis 2007, 13:1397-1405.
-
(2007)
Mol Vis
, vol.13
, pp. 1397-1405
-
-
Mulhern, M.L.1
Madson, C.J.2
Kador, P.F.3
Randazzo, J.4
Shinohara, T.5
-
88
-
-
68349098938
-
Correction of the disease phenotype of myocilin-causing glaucoma by a natural osmolyte
-
Jia L.Y., Gong B., Pang C.P., Huang Y., Lam D.S., Wang N., et al. Correction of the disease phenotype of myocilin-causing glaucoma by a natural osmolyte. Invest Ophthalmol Vis Sci 2009, 50:3743-3749.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 3743-3749
-
-
Jia, L.Y.1
Gong, B.2
Pang, C.P.3
Huang, Y.4
Lam, D.S.5
Wang, N.6
-
89
-
-
84899762285
-
Chemical chaperones mitigate experimental asthma by attenuating endoplasmic reticulum stress
-
Makhija L., Krishnan V., Rehman R., Chakraborty S., Maity S., Mabalirajan U., et al. Chemical chaperones mitigate experimental asthma by attenuating endoplasmic reticulum stress. Am J Respir Cell Mol Biol 2014, 50:923-931.
-
(2014)
Am J Respir Cell Mol Biol
, vol.50
, pp. 923-931
-
-
Makhija, L.1
Krishnan, V.2
Rehman, R.3
Chakraborty, S.4
Maity, S.5
Mabalirajan, U.6
-
90
-
-
0036073289
-
Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch
-
Yoshida H., Yoshizawa T., Shibasaki F., Shoji S., Kanazawa I. Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch. Neurobiol Dis 2002, 10:88-99.
-
(2002)
Neurobiol Dis
, vol.10
, pp. 88-99
-
-
Yoshida, H.1
Yoshizawa, T.2
Shibasaki, F.3
Shoji, S.4
Kanazawa, I.5
-
91
-
-
33845379319
-
Nucleophilic opening of 2, 3-epoxy acids and amides mediated by titanium isopropoxide. Highly enhanced C-3 selectivity
-
Chong J.M., Sharpless K.B. Nucleophilic opening of 2, 3-epoxy acids and amides mediated by titanium isopropoxide. Highly enhanced C-3 selectivity. J Org Chem 1985, 50:1560-1563.
-
(1985)
J Org Chem
, vol.50
, pp. 1560-1563
-
-
Chong, J.M.1
Sharpless, K.B.2
-
92
-
-
0014781246
-
Improved preparation of tertiary amine N-oxides
-
Cymerman Craig J., Purushothaman K. Improved preparation of tertiary amine N-oxides. J Org Chem 1970, 35:1721-1722.
-
(1970)
J Org Chem
, vol.35
, pp. 1721-1722
-
-
Cymerman Craig, J.1
Purushothaman, K.2
-
93
-
-
0000113803
-
The biosynthesis of trimethylamine-N-oxide
-
Baker J., Chaykin S. The biosynthesis of trimethylamine-N-oxide. J Biol Chem 1962, 237:1309-1313.
-
(1962)
J Biol Chem
, vol.237
, pp. 1309-1313
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Baker, J.1
Chaykin, S.2
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