Utilization of glycerophosphodiesters by Staphylococcus aureus

Molecular Microbiology

Volumn 103, Issue 2, 2017, Pages 229-241

  Jorge, Ana Maria ^a   Schneider, Jonathan ^a   Unsleber, Sandra ^a   Göhring, Nadine ^a   Mayer, Christoph ^a   Peschel, Andreas ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCEROPHOSPHODIESTERASE; PHOSPHATIDYLCHOLINE; PHOSPHODIESTERASE; PHOSPHOLIPID; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; GLPQ PROTEIN, BACTERIA; GLYCEROPHOSPHATE; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE;

ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; CARBON SOURCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE DELETION; HUMAN; HUMAN TISSUE; HYDROLYSIS; NONHUMAN; NUTRITION; PHOSPHATE SOURCE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM;

BACTERIAL PROTEINS; GLYCEROPHOSPHATES; PHOSPHATIDYLCHOLINES; PHOSPHOLIPIDS; PHOSPHORIC DIESTER HYDROLASES; STAPHYLOCOCCUS AUREUS;

EID: 84997712053     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.13552     Document Type: Article

References (38)

1. Brown, S.A., Palmer, K.L., and Whiteley, M. (2008) Revisiting the host as a growth medium. Nat Rev Microbiol 6: 657–666.
2. Burke, W. (2014) The Ionic Composition of Nasal Fluid and Its Function. Health 6: 720–728.
3. Chang, A., Schomburg, I., Placzek, S., Jeske, L., Ulbrich, M., Xiao, M., et al. (2015) BRENDA in 2015: Exciting developments in its 25th year of existence. Nucleic Acids Res 43: D439–D446. 4
4. Clark, S.E., and Weiser, J.N. (2013) Microbial modulation of host immunity with the small molecule phosphorylcholine. Infect Immun 81: 392–401.
5. Corda, D., Mosca, M.G., Ohshima, N., Grauso, L., Yanaka, N., and Mariggio, S. (2014) The emerging physiological roles of the glycerophosphodiesterase family. Febs J 281: 998–1016.
6. Fan, X., Goldfine, H., Lysenko, E., and Weiser, J.N. (2001) The transfer of choline from the host to the bacterial cell surface requires glpQ in Haemophilus influenzae. Mol Microbiol 41: 1029–1036.
7. Fedtke, I., Mader, D., Kohler, T., Moll, H., Nicholson, G., Biswas, R., et al. (2007) A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity. Mol Microbiol 65: 1078–1091.
8. Fowler, V.G., Jr., and Proctor, R.A. (2014) Where does a Staphylococcus aureus vaccine stand? Clin Microbiol Infect 20: 66–75.
9. Gallazzini, M., Ferraris, J.D., and Burg, M.B. (2008) GDPD5 is a glycerophosphocholine phosphodiesterase that osmotically regulates the osmoprotective organic osmolyte GPC. Proc Natl Acad Sci U S A 105: 11026–11031.
10. Garcia-Perez, A., and Burg, M.B. (1991) Renal medullary organic osmolytes. Physiol Rev 71: 1081–1115.
11. Gibson, D.G., Young, L., Chuang, R.Y., Venter, J.C., Hutchison, C.A., III, and Smith, H.O. (2009) Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat Methods 6: 343–345.
12. Gong, J.Q., Lin, L., Lin, T., Hao, F., Zeng, F.Q., Bi, Z.G., et al. (2006) Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: A double-blind multicentre randomized controlled trial. Br J Dermatol 155: 680–687.
13. Huynh, T.N., Luo, S., Pensinger, D., Sauer, J.D., Tong, L., and Woodward, J.J. (2015) An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence. Proc Natl Acad Sci U S A 112: E747–E756. 7
14. Janek, D., Zipperer, A., Kulik, A., Krismer, B., and Peschel, A. (2016) High Frequency and Diversity of Antimicrobial Activities Produced by Nasal Staphylococcus Strains against Bacterial Competitors. PLoS Pathog 12: e1005812.
15. Kolata, J., Bode, L.G., Holtfreter, S., Steil, L., Kusch, H., Holtfreter, B., Albrecht, D., Hecker, M., et al. (2011) Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non-carriers. Proteomics 11: 3914–3927.
16. Kopp, F., Komatsu, T., Nomura, D.K., Trauger, S.A., Thomas, J.R., Siuzdak, G., et al. (2010) The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice. Chem Biol 17: 831–840.
17. Krismer, B., Liebeke, M., Janek, D., Nega, M., Rautenberg, M., Hornig, G., et al. (2014) Nutrient limitation governs Staphylococcus aureus metabolism and niche adaptation in the human nose. PLoS Pathog 10: e1003862.
18. Kusch, H., and Engelmann, S. (2014) Secrets of the secretome in Staphylococcus aureus. Int J Med Microbiol 304: 133–141.
19. Larson, T.J., Ehrmann, M., and Boos, W. (1983) Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon. J Biol Chem 258: 5428–5432.
20. Lin, L., Huang, Z., Gao, Y., Chen, Y., Hang, W., Xing, J., and Yan, X. (2012) LC-MS-based serum metabolic profiling for genitourinary cancer classification and cancer type-specific biomarker discovery. Proteomics 12: 2238–2246.
21. Lorin, M.I., Gaerlan, P.F., and Mandel, I.D. (1972) Quantitative composition of nasal secretions in normal subjects. J Lab Clin Med 80: 275–281.
22. Monk, I.R., Shah, I.M., Xu, M., Tan, M.W., and Foster, T.J. (2012) Transforming the untransformable: Application of direct transformation to manipulate genetically Staphylococcus aureus and Staphylococcus epidermidis. MBio 3:
23. Ohshima, N., Yamashita, S., Takahashi, N., Kuroishi, C., Shiro, Y., and Takio, K. (2008) Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity. J Bacteriol 190: 1219–1223.
24. Otto, M. (2012) MRSA virulence and spread. Cell Microbiol 14: 1513–1521.
25. Park, J.Y., Kim, J.W., Moon, B.Y., Lee, J., Fortin, Y.J., Austin, F.W., et al. (2015) Characterization of a novel two-component regulatory system, HptRS, the regulator for the hexose phosphate transport system in Staphylococcus aureus. Infect Immun 83: 1620–1628.
26. Park, Y.D., Jang, J.H., Oh, Y.J., and Kwon, H.J. (2014) Analyses of organic acids and inorganic anions and their relationship in human saliva before and after glucose intake. Arch Oral Biol 59: 1–11.
27. Portale, A.A., Halloran, B.P., and Morris, R.C., Jr. (1987) Dietary intake of phosphorus modulates the circadian rhythm in serum concentration of phosphorus. Implications for the renal production of 1,25-dihydroxyvitamin D. J Clin Invest 80: 1147–1154.
28. Schmidl, S.R., Otto, A., Lluch-Senar, M., Pinol, J., Busse, J., Becher, D., and Stulke, J. (2011) A trigger enzyme in Mycoplasma pneumoniae: Impact of the glycerophosphodiesterase GlpQ on virulence and gene expression. PLoS Pathog 7: e1002263.
29. Somerville, G.A., and Proctor, R.A. (2009) At the crossroads of bacterial metabolism and virulence factor synthesis in Staphylococci. Microbiol Mol Biol Rev 73: 233–248.
30. Stentzel, S., Sundaramoorthy, N., Michalik, S., et al. (2015) Specific serum IgG at diagnosis of Staphylococcus aureus bloodstream invasion is correlated with disease progression. J Proteomics 128: 1–7.
31. Watson, S.P., Clements, M.O., and Foster, S.J. (1998) Characterization of the starvation-survival response of Staphylococcus aureus. J Bacteriol 180: 1750–1758.
32. Weidenmaier, C., Goerke, C., and Wolz, C. (2012) Staphylococcus aureus determinants for nasal colonization. Trends Microbiol 20: 243–250.
33. Wertheim, H.F., Melles, D.C., Vos, M.C., van Leeuwen, W., van Belkum, A., Verbrugh, H.A., and Nouwen, J.L. (2005) The role of nasal carriage in Staphylococcus aureus infections. Lancet Infect Dis 5: 751–762.
34. Winstel, V., Sanchez-Carballo, P., Holst, O., Xia, G., and Peschel, A. (2014) Biosynthesis of the unique wall teichoic acid of Staphylococcus aureus lineage ST395. MBio 5: e00869.
35. Wishart, D.S., Jewison, T., Guo, A.C., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., et al. (2013) HMDB 3.0–The Human Metabolome Database in 2013. Nucleic Acids Res 41: D801–D807.
36. Ziebandt, A.K., Becher, D., Ohlsen, K., Hacker, J., Hecker, M., and Engelmann, S. (2004) The influence of agr and sigmaB in growth phase dependent regulation of virulence factors in Staphylococcus aureus. Proteomics 4: 3034–3047.
37. Ziebandt, A.K., Kusch, H., Degner, M., Jaglitz, S., Sibbald, M.J., Arends, J.P., Chlebowicz, M.A., Albrecht, D., et al. (2010) Proteomics uncovers extreme heterogeneity in the Staphylococcus aureus exoproteome due to genomic plasticity and variant gene regulation. Proteomics 10: 1634–1644.
38. Zipperer, A., Konnerth, M.C., Laux, C., Berscheid, A., Janek, D., Weidenmaier, C., Burian, M., Schilling, N.A., et al. (2016) Human commensals producing a novel antibiotic impair pathogen colonization. Nature 535: 511–516.