Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non-carriers

Proteomics

Volumn 11, Issue 19, 2011, Pages 3914-3927

  Kolata, Julia ^a   Bode, Lonneke G M ^b   Holtfreter, Silva ^a   Steil, Leif ^a   Kusch, Harald ^a   Holtfreter, Birte ^a   Albrecht, Dirk ^a   Hecker, Michael ^a   Engelmann, Susanne ^a   Van Belkum, Alex ^b,c   Völker, Uwe ^a   Bröker, Barbara M ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c BIOMÉRIEUX   (France)

Author keywords

2 D immunoblotting; Antibody; Microbiology; Protein identification; Secreted proteome; Staphylococcus aureus bacteremia

Indexed keywords

ACYLGLYCEROL LIPASE; ALPHA HEMOLYSIN; AUTOLYSIN; BACTERIAL PROTEIN; BETA LACTAMASE; HYALURONIDASE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; N ACETYLMURAMOYLALANINE AMIDASE; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL LYASE; TRIACYLGLYCEROL LIPASE;

ADULT; AGED; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; BACTERIAL STRAIN; BACTERIUM CARRIER; FEMALE; HUMAN; IMMUNIZATION; IMMUNOCOMPETENCE; MALE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN ANALYSIS; STAPHYLOCOCCAL BACTEREMIA; STAPHYLOCOCCUS AUREUS;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODY FORMATION; BACTEREMIA; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PROTEOME; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; YOUNG ADULT;

STAPHYLOCOCCUS AUREUS;

EID: 79960413315     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201000760     Document Type: Article

References (57)

1. Pittet, D., Wenzel, R. P., Nosocomial bloodstream infections. Secular trends in rates, mortality, and contribution to total hospital deaths. Arch. Intern. Med. 1995, 155, 1177-1184.
2. Boucher, H. W., Corey, G. R., Epidemiology of methicillin-resistant Staphylococcus aureus. Clin. Infect. Dis. 2008, 46, S344-349.
3. Concia, E., Prandini, N., Massari, L., Ghisellini, F. et al., Osteomyelitis: clinical update for practical guidelines. Nucl. Med. Commun. 2006, 27, 645-660.
4. Dryden, M. S., Skin and soft tissue infection: microbiology and epidemiology. Int. J. Antimicrob. Agents 2009, 34, S2-S7.
5. Fluit, A. C., Wielders, C. L., Verhoef, J., Schmitz, F. J., Epidemiology and susceptibility of 3, 051 Staphylococcus aureus isolates from 25 university hospitals participating in the European SENTRY study. J. Clin. Microbiol. 2001, 39, 3727-3732.
6. Lina, G., Piemont, Y., Godail-Gamot, F., Bes, M. et al., Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin. Infect. Dis. 1999, 29, 1128-1132.
7. Wertheim, H. F., Vos, M. C., Ott, A., van Belkum, A. et al., Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers. Lancet 2004, 364, 703-705.
8. Chambers, H. F., Community-associated MRSA - resistance and virulence converge. N. Engl. J. Med. 2005, 352, 1485-1487.
9. Garcia-Lara, J., Foster, S. J., Anti-Staphylococcus aureus immunotherapy: current status and prospects. Curr. Opin. Pharmacol. 2009, 9, 552-557.
10. Schaffer, A. C., Lee, J. C., Staphylococcal vaccines and immunotherapies. Infect. Dis. Clin. North Am. 2009, 23, 153-171.
11. Foster, T. J., Immune evasion by staphylococci. Nat. Rev. Microbiol. 2005, 3, 948-958.
12. Rooijakkers, S. H., van Strijp, J. A., Bacterial complement evasion. Mol. Immunol. 2007, 44, 23-32.
13. Goerke, C., Pantucek, R., Holtfreter, S., Schulte, B. et al., Diversity of prophages in dominant Staphylococcus aureus clonal lineages. J. Bacteriol. 2009, 191, 3462-3468.
14. Holtfreter, S., Grumann, D., Schmudde, M., Nguyen, H. T. et al., Clonal distribution of superantigen genes in clinical Staphylococcus aureus isolates. J. Clin. Microbiol. 2007, 45, 2669-2680.
15. Lindsay, J. A., Holden, M. T., Staphylococcus aureus: superbug, super genome? Trends Microbiol. 2004, 12, 378-385.
16. Novick, R. P., Subedi, A., The SaPIs: mobile pathogenicity islands of Staphylococcus. Chem. Immunol. Allergy 2007, 93, 42-57.
17. Verkaik, N. J., Dauwalder, O., Antri, K., Boubekri, I. et al., Immunogenicity of toxins during Staphylococcus aureus infection. Clin. Infect. Dis. 2010, 50, 61-68.
18. Ziebandt, A. K., Kusch, H., Degner, M., Jaglitz, S. et al., Proteomics uncovers extreme heterogeneity in the Staphylococcus aureus exoproteome due to genomic plasticity and variant gene regulation. Proteomics 2010, 10, 1634-1644.
19. Dreisbach, A., Hempel, K., Buist, G., Hecker, M. et al., Profiling the surfacome of Staphylococcus aureus. Proteomics 2010, 10, 3082-3096.
20. Sibbald, M. J. J. B., Ziebandt, A. K., Engelmann, S., Hecker, M. et al., Mapping the pathways to staphylococcal pathogenesis by comparative secretomics. Microbiol. Mol. Biol. Rev. 2006, 70, 755-788.
21. Acton, D. S., Plat-Sinnige, M. J., van Wamel, W., de Groot, N., van Belkum, A., Intestinal carriage of Staphylococcus aureus: how does its frequency compare with that of nasal carriage and what is its clinical impact? Eur. J. Clin. Microbiol. Infect. Dis. 2009, 28, 115-127.
22. Mertz, D., Frei, R., Periat, N., Zimmerli, M. et al., Exclusive Staphylococcus aureus throat carriage: at-risk populations. Arch. Intern. Med. 2009, 169, 172-178.
23. Wertheim, H. F., Melles, D. C., Vos, M. C., van Leeuwen, W. et al., The role of nasal carriage in Staphylococcus aureus infections. Lancet Infect. Dis. 2005, 5, 751-762.
24. Holtfreter, S., Nguyen, T. T., Wertheim, H., Steil, L. et al., Human immune proteome in experimental colonization with Staphylococcus aureus. Clin. Vaccine Immunol. 2009, 16, 1607-1614.
25. Holtfreter, S., Roschack, K., Eichler, P., Eske, K. et al., Staphylococcus aureus carriers neutralize superantigens by antibodies specific for their colonizing strain: a potential explanation for their improved prognosis in severe sepsis. J. Infect. Dis. 2006, 193, 1275-1278.
26. Verkaik, N. J., de Vogel, C. P., Boelens, H. A., Grumann, D. et al., Anti-staphylococcal humoral immune response in persistent nasal carriers and noncarriers of Staphylococcus aureus. J. Infect. Dis. 2009, 199, 625-632.
27. Colque-Navarro, P., Palma, M., Soderquist, B., Flock, J. I., Mollby, R., Antibody responses in patients with staphylococcal septicemia against two Staphylococcus aureus fibrinogen binding proteins: clumping factor and an extracellular fibrinogen binding protein. Clin. Diagn. Lab. Immunol. 2000, 7, 14-20.
28. Colque-Navarro, P., Soderquist, B., Holmberg, H., Blomqvist, L. et al., Antibody response in Staphylococcus aureus septicaemia - a prospective study. J. Med. Microbiol. 1998, 47, 217-225.
29. Dryla, A., Prustomersky, S., Gelbmann, D., Hanner, M. et al., Comparison of antibody repertoires against Staphylococcus aureus in healthy individuals and in acutely infected patients. Clin. Diagn. Lab. Immunol. 2005, 12, 387-398.
30. Lorenz, U., Ohlsen, K., Karch, H., Thiede, A., Hacker, J., Immunodominant proteins in human sepsis caused by methicillin resistant Staphylococcus aureus. Adv. Exp. Med. Biol. 2000, 485, 273-278.
31. Ryding, U., Christensson, B., Soderquist, B., Wadstrom, T., Antibody response to Staphylococcus aureus collagen binding protein in patients with S. aureus septicaemia and collagen binding properties of corresponding strains. J. Med. Microbiol. 1995, 43, 328-334.
32. Vytvytska, O., Nagy, E., Bluggel, M., Meyer, H. E. et al., Identification of vaccine candidate antigens of Staphylococcus aureus by serological proteome analysis. Proteomics 2002, 2, 580-590.
33. von Eiff, C., Becker, K., Machka, K., Stammer, H., Peters, G., Nasal carriage as a source of Staphylococcus aureus bacteremia. Study Group. N. Engl. J. Med. 2001, 344, 11-16.
34. Jungblut, P. R., Grabher, G., Stöffler, G., Comprehensive detection of immunorelevant Borrelia garinii antigens by two-dimensional electrophoresis. Electrophoresis 1999, 20, 3611-3622.
35. Bode, L. G., Kluytmans, J. A., Wertheim, H. F., Bogaers, D. et al., Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N. Engl. J. Med. 2010, 362, 9-17.
36. Singer, J., Willett, J., Applied Longitudinal Data Analysis, Oxford University Press, Inc., New York 2003.
37. Lorenz, U., Lorenz, B., Schmitter, T., Streker, K. et al., Functional antibodies targeting IsaA of Staphylococcus aureus augment host immune response and open new perspectives for antibacterial therapy. Antimicrob. Agents Chemother. 2011, 55, 165-173.
38. Lorenz, U., Ohlsen, K., Karch, H., Hecker, M. et al., Human antibody response during sepsis against targets expressed by methicillin resistant Staphylococcus aureus. FEMS Immunol. Med. Microbiol. 2000, 29, 145-153.
39. Jacobsson, G., Colque-Navarro, P., Gustafsson, E., Andersson, R., Mollby, R., Antibody responses in patients with invasive Staphylococcus aureus infections. Eur. J. Clin. Microbiol. Infect. Dis. 2010, 29, 715-725.
40. Schlievert, P. M., Use of intravenous immunoglobulin in the treatment of staphylococcal and streptococcal toxic shock syndromes and related illnesses. J. Allergy Clin. Immunol. 2001, 108, S107-S110.
41. Stolz, S. J., Davis, J. P., Vergeront, J. M., Crass, B. A. et al., Development of serum antibody to toxic shock toxin among individuals with toxic shock syndrome in Wisconsin. J. Infect. Dis. 1985, 151, 883-889.
42. Clarke, S. R., Brummell, K. J., Horsburgh, M. J., McDowell, P. W. et al., Identification of in vivo-expressed antigens of Staphylococcus aureus and their use in vaccinations for protection against nasal carriage. J. Infect. Dis. 2006, 193, 1098-1108.
43. Holtfreter, S., Kolata, J., Broker, B. M., Towards the immune proteome of Staphylococcus aureus - the anti-S. aureus antibody response. Int. J. Med. Microbiol. 2010, 300, 176-192.
44. Etz, H., Minh, D. B., Henics, T., Dryla, A. et al., Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureus. Proc. Natl. Acad. Sci. USA 2002, 99, 6573-6578.
45. Weichhart, T., Horky, M., Sollner, J., Gangl, S. et al., Functional selection of vaccine candidate peptides from Staphylococcus aureus whole-genome expression libraries in vitro. Infect. Immun. 2003, 71, 4633-4641.
46. Kaneko, J., Kamio, Y., Bacterial two-component and hetero-heptameric pore-forming cytolytic toxins: structures, pore-forming mechanism, and organization of the genes. Biosci. Biotechnol. Biochem. 2004, 68, 981-1003.
47. Christensson, B., Hedstrom, S. A., Kronvall, G., The clinical significance of serological methods in the diagnosis of staphylococcal septicaemia and endocarditis. Scand. J. Infect. Dis. Suppl. 1983, 41, 140-143.
48. Bubeck Wardenburg, J., Schneewind, O., Vaccine protection against Staphylococcus aureus pneumonia. J. Exp. Med. 2008, 205, 287-294.
49. Imamura, T., Tanase, S., Szmyd, G., Kozik, A. et al., Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus. J. Exp. Med. 2005, 201, 1669-1676.
50. Ohbayashi, T., Irie, A., Murakami, Y., Nowak, M. et al., Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus. Microbiology 2011, 157, 786-792.
51. Verkaik, N., Brouwer, E., Hooijkaas, H., van Belkum, A., van Wamel, W., Comparison of carboxylated and Penta-His microspheres for semi-quantitative measurement of antibody responses to His-tagged proteins. J. Immunol. Methods 2008, 335, 121-125.
52. Parker, D. C., T cell-dependent B cell activation. Annu. Rev. Immunol. 1993, 11, 331-360.
53. Macpherson, A. J., Harris, N. L., Interactions between commensal intestinal bacteria and the immune system. Nat. Rev. Immunol. 2004, 4, 478-485.
54. Norrby-Teglund, A., Chatellier, S., Low, D. E., McGeer, A. et al., Host variation in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection. Eur. J. Immunol. 2000, 30, 3247-3255.
55. Norrby-Teglund, A., Lustig, R., Kotb, M., Differential induction of Th1 versus Th2 cytokines by group A streptococcal toxic shock syndrome isolates. Infect. Immun. 1997, 65, 5209-5215.
56. Cho, J. S., Pietras, E. M., Garcia, N. C., Ramos, R. I. et al., IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J. Clin. Invest. 2010, 120, 1762-1773.
57. Lin, L., Ibrahim, A. S., Xu, X., Farber, J. M. et al., Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice. PLoS Pathog. 2009, 5, e1000703.