Activation of TGF-β1 by AQP3-Mediated H2O2 Transport into Fibroblasts of a Bleomycin-Induced Mouse Model of Scleroderma

Journal of Investigative Dermatology

Volumn 136, Issue 12, 2016, Pages 2372-2379

  Luo, Jingying ^a,b   Liu, Xin ^c   Liu, Jie ^a   Jiang, Miao ^a   Luo, Miao ^b   Zhao, Jingjun ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b GUILIN MEDICAL UNIVERSITY   (China)

^c KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN 3; BLEOMYCIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; HYDROGEN PEROXIDE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; FEMALE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCLERODERMA; SKIN FIBROBLAST; SKIN FIBROSIS; ANALYSIS OF VARIANCE; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CHEMICALLY INDUCED; DISEASE MODEL; FIBROBLAST; LOCALIZED SCLERODERMA; METABOLISM; NEEDLE BIOPSY; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; RANDOMIZATION; REAL TIME POLYMERASE CHAIN REACTION; TRANSPORT AT THE CELLULAR LEVEL; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL TRANSPORT; BIOPSY, NEEDLE; BLEOMYCIN; BLOTTING, WESTERN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLASTS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; RANDOM ALLOCATION; REAL-TIME POLYMERASE CHAIN REACTION; SCLERODERMA, LOCALIZED; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84997501202     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1016/j.jid.2016.07.014     Document Type: Article

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