Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo

Neuron

Volumn 92, Issue 4, 2016, Pages 796-812

  Kaufman, Sarah K ^a,c   Sanders, David W ^a,c   Thomas, Talitha L ^c   Ruchinskas, Allison J ^c   Vaquer Alicea, Jaime ^c   Sharma, Apurwa M ^a,c   Miller, Timothy M ^b   Diamond, Marc I ^c  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

cell model; prion; prion like; seeding activity; strain; tau; tau pathology; tauopathy; transcellular propagation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BIOLOGICAL TRAIT; BRAIN REGION; CELLS BY BODY ANATOMY; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVOUS SYSTEM PARAMETERS; NEUROPATHOLOGY; NONHUMAN; PRION; PRIORITY JOURNAL; TAUOPATHY; TRANSGENIC MOUSE; VIRUS CELL INTERACTION; VIRUS STRAIN; ANIMAL; BRAIN; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOLOGY;

PRION PROTEIN; TAU PROTEIN;

ANIMALS; BRAIN; DISEASE PROGRESSION; HEK293 CELLS; HUMANS; MICE; MICE, TRANSGENIC; PRION PROTEINS; TAU PROTEINS; TAUOPATHIES;

EID: 84997417099     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2016.09.055     Document Type: Article

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