The Intestinal Microbiota in the Irritable Bowel Syndrome

International Review of Neurobiology

Volumn 131, Issue , 2016, Pages 247-261

  Collins, S M ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Anxiety; Bacteria; Behavior; Brain; Depression; Gastrointestinal diseases; Germ free mice; Metabolomics; Microbiome; Psychiatry

Indexed keywords

ANTIBIOTIC AGENT; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; MU OPIATE RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; RIFAMPICIN; TOLL LIKE RECEPTOR 4;

ACUTE GASTROENTERITIS; ANXIETY DISORDER; CARBOHYDRATE INTAKE; CASE CONTROL STUDY; COMORBIDITY; DISEASE EXACERBATION; DISEASE PREDISPOSITION; DYSBIOSIS; EARLY LIFE STRESS; GASTROINTESTINAL MOTILITY; GEL ELECTROPHORESIS; HOST PATHOGEN INTERACTION; HUMAN; INTESTINE FLORA; IRRITABLE COLON; LIFESTYLE; MENTAL STRESS; MICROBIAL COLONIZATION; NONHUMAN; PATHOGENESIS; PHENOTYPE; PHYLOGENY; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOCIAL STRESS; VISCERAL PAIN; ANIMAL; BRAIN; MICROBIOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BRAIN; GASTROINTESTINAL MICROBIOME; HUMANS; IRRITABLE BOWEL SYNDROME;

EID: 84997125520     PISSN: 00747742     EISSN: 21625514     Source Type: Book Series    
DOI: 10.1016/bs.irn.2016.08.003     Document Type: Chapter

References (49)

1. Aguilera, M., Cerda-Cuellar, M., Martinez, V., Antibiotic-induced dysbiosis alters host–bacterial interactions and leads to colonic sensory and motor changes in mice. Gut Microbes 6:1 (2015), 10–23, 10.4161/19490976.2014.990790.
2. Aguilera, M., Vergara, P., Martinez, V., Stress and antibiotics alter luminal and wall-adhered microbiota and enhance the local expression of visceral sensory-related systems in mice. Neurogastroenterology and Motility 25:8 (2013), e515–e529, 10.1111/nmo.12154.
3. Anitha, M., Vijay-Kumar, M., Sitaraman, S.V., Gewirtz, A.T., Srinivasan, S., Gut microbial products regulate murine gastrointestinal motility via Toll-like receptor 4 signaling. Gastroenterology 143:4 (2012), 1006–1016, 10.1053/j.gastro.2012.06.034 e1004.
4. Bailey, M.T., Dowd, S.E., Galley, J.D., Hufnagle, A.R., Allen, R.G., Lyte, M., Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation. Brain, Behavior, and Immunity 25:3 (2011), 397–407, 10.1016/j.bbi.2010.10.023.
5. Bercik, P., Denou, E., Collins, J., Jackson, W., Lu, J., Jury, J., Collins, S.M., The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology 141:2 (2011), 599–609, 10.1053/j.gastro.2011.04.052 e591–593.
6. Blaser, M.J., Antibiotic use and its consequences for the normal microbiome. Science 352:6285 (2016), 544–545, 10.1126/science.aad9358.
7. Bradford, K., Shih, W., Videlock, E.J., Presson, A.P., Naliboff, B.D., Mayer, E.A., Chang, L., Association between early adverse life events and irritable bowel syndrome. Clinical Gastroenterology and Hepatology 10:4 (2012), 385–390, 10.1016/j.cgh.2011.12.018 e381–383.
8. Collins, S.M., Kassam, Z., Bercik, P., The adoptive transfer of behavioral phenotype via the intestinal microbiota: Experimental evidence and clinical implications. Current Opinion in Microbiology 16:3 (2013), 240–245, 10.1016/j.mib.2013.06.004.
9. Collins, S.M., Surette, M., Bercik, P., The interplay between the intestinal microbiota and the brain. Nature Reviews. Microbiology 10:11 (2012), 735–742, 10.1038/nrmicro2876.
10. Crouzet, L., Gaultier, E., Del'Homme, C., Cartier, C., Delmas, E., Dapoigny, M., Bernalier-Donadille, A., The hypersensitivity to colonic distension of IBS patients can be transferred to rats through their fecal microbiota. Neurogastroenterology and Motility 25:4 (2013), e272–e282, 10.1111/nmo.12103.
11. De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J.B., Massart, S., Lionetti, P., Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proceedings of the National Academy of Sciences of the United States of America 107:33 (2010), 14691–14696, 10.1073/pnas.1005963107.
12. De Giorgio, R., Volta, U., Gibson, P.R., Sensitivity to wheat, gluten and FODMAPs in IBS: Facts or fiction?. Gut 65:1 (2016), 169–178, 10.1136/gutjnl-2015-309757.
13. De Palma, G., Blennerhassett, P., Lu, J., Deng, Y., Park, A.J., Green, W., Bercik, P., Microbiota and host determinants of behavioural phenotype in maternally separated mice. Nature Communications, 6, 2015, 7735, 10.1038/ncomms8735.
14. De Palma, G., Lynch, M.D., Lu, J., Deng, Y., Jury, J., McLean, P., Bercik, P., The adoptive transfer of anxiety and gut dysfunction from IBS patients to axenic mice through microbiota transplantation. Gastroenterology, 146(5), 2014, S845.
15. Diaz Heijtz, R., Wang, S., Anuar, F., Qian, Y., Bjorkholm, B., Samuelsson, A., Pettersson, S., Normal gut microbiota modulates brain development and behavior. Proceedings of the National Academy of Sciences of the United States of America 108:7 (2011), 3047–3052, 10.1073/pnas.1010529108.
16. Dunlop, S.P., Coleman, N.S., Blackshaw, E., Perkins, A.C., Singh, G., Marsden, C.A., Spiller, R.C., Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome. Clinical Gastroenterology and Hepatology 3:4 (2005), 349–357.
17. Durban, A., Abellan, J.J., Jimenez-Hernandez, N., Artacho, A., Garrigues, V., Ortiz, V., Moya, A., Instability of the faecal microbiota in diarrhoea-predominant irritable bowel syndrome. FEMS Microbiology Ecology 86:3 (2013), 581–589, 10.1111/1574-6941.12184.
18. Fond, G., Loundou, A., Hamdani, N., Boukouaci, W., Dargel, A., Oliveira, J., Boyer, L., Anxiety and depression comorbidities in irritable bowel syndrome (IBS): A systematic review and meta-analysis. European Archives of Psychiatry and Clinical Neuroscience 264:8 (2014), 651–660, 10.1007/s00406-014-0502-z.
19. Gwee, K.A., Leong, Y.L., Graham, C., McKendrick, M.W., Collins, S.M., Walters, S.J., Read, N.W., The role of psychological and biological factors in postinfective gut dysfunction. Gut 44:3 (1999), 400–406.
20. Jalanka, J., Salonen, A., Fuentes, S., de Vos, W.M., Microbial signatures in post-infectious irritable bowel syndrome—Toward patient stratification for improved diagnostics and treatment. Gut Microbes 6:6 (2015), 364–369, 10.1080/19490976.2015.1096486.
21. Jalanka-Tuovinen, J., Salojarvi, J., Salonen, A., Immonen, O., Garsed, K., Kelly, F.M., de Vos, W.M., Faecal microbiota composition and host-microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome. Gut 63:11 (2014), 1737–1745, 10.1136/gutjnl-2013-305994.
22. Jeffery, I.B., Claesson, M.J., O'Toole, P.W., Shanahan, F., Categorization of the gut microbiota: Enterotypes or gradients?. Nature Reviews. Microbiology 10:9 (2012), 591–592.
23. Jenkins, T.A., Nguyen, J.C., Polglaze, K.E., Bertrand, P.P., Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis. Nutrients, 8(1), 2016, 56, 10.3390/nu8010056 http://www.mdpi.com/2072-6643/8/1/56.
24. Kajander, K., Myllyluoma, E., Rajilic-Stojanovic, M., Kyronpalo, S., Rasmussen, M., Jarvenpaa, S., Korpela, R., Clinical trial: Multispecies probiotic supplementation alleviates the symptoms of irritable bowel syndrome and stabilizes intestinal microbiota. Alimentary Pharmacology & Therapeutics 27:1 (2008), 48–57, 10.1111/j.1365-2036.2007.03542.x.
25. Li, W., Dowd, S.E., Scurlock, B., Acosta-Martinez, V., Lyte, M., Memory and learning behavior in mice is temporally associated with diet-induced alterations in gut bacteria. Physiology & Behavior 96:4–5 (2009), 557–567, 10.1016/j.physbeh.2008.12.004.
26. Marshall, J.K., Thabane, M., Garg, A.X., Clark, W.F., Moayyedi, P., Collins, S.M., Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery. Gut 59:5 (2010), 605–611, 10.1136/gut.2009.202234.
27. Matto, J., Maunuksela, L., Kajander, K., Palva, A., Korpela, R., Kassinen, A., Saarela, M., Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome—A longitudinal study in IBS and control subjects. FEMS Immunology and Medical Microbiology 43:2 (2005), 213–222.
28. Maukonen, J., Satokari, R., Matto, J., Soderlund, H., Mattila-Sandholm, T., Saarela, M., Prevalence and temporal stability of selected clostridial groups in irritable bowel syndrome in relation to predominant faecal bacteria. Journal of Medical Microbiology 55:Pt. 5 (2006), 625–633, 10.1099/jmm.0.46134-0.
29. Maxwell, P.R., Rink, E., Kumar, D., Mendall, M.A., Antibiotics increase functional abdominal symptoms. The American Journal of Gastroenterology 97:1 (2002), 104–108, 10.1111/j.1572-0241.2002.05428.x.
30. Neufeld, K.M., Kang, N., Bienenstock, J., Foster, J.A., Reduced anxiety-like behavior and central neurochemical change in germ-free mice. Neurogastroenterology and Motility 23:3 (2011), 255–264, 10.1111/j.1365-2982.2010.01620.x e119.
31. O'Mahony, S.M., Felice, V.D., Nally, K., Savignac, H.M., Claesson, M.J., Scully, P., Cryan, J.F., Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats. Neuroscience 277 (2014), 885–901, 10.1016/j.neuroscience.2014.07.054.
32. Paula, H., Grover, M., Halder, S.L., Locke, G.R. 3rd, Schleck, C.D., Zinsmeister, A.R., Talley, N.J., Non-enteric infections, antibiotic use, and risk of development of functional gastrointestinal disorders. Neurogastroenterology and Motility 27:11 (2015), 1580–1586, 10.1111/nmo.12655.
33. Pimentel, M., Review article: Potential mechanisms of action of rifaximin in the management of irritable bowel syndrome with diarrhoea. Alimentary Pharmacology & Therapeutics 43:Suppl. 1 (2016), 37–49, 10.1111/apt.13437.
34. Pinto-Sanchez, M.I., Bercik, P., Verdu, E.F., Motility alterations in celiac disease and non-celiac gluten sensitivity. Digestive Diseases 33:2 (2015), 200–207, 10.1159/000371400.
35. Pusceddu, M.M., Kelly, P., Ariffin, N., Cryan, J.F., Clarke, G., Dinan, T.G., n-3 PUFAs have beneficial effects on anxiety and cognition in female rats: Effects of early life stress. Psychoneuroendocrinology 58 (2015), 79–90, 10.1016/j.psyneuen.2015.04.015.
36. Qin, H.Y., Cheng, C.W., Tang, X.D., Bian, Z.X., Impact of psychological stress on irritable bowel syndrome. World Journal of Gastroenterology 20:39 (2014), 14126–14131, 10.3748/wjg.v20.i39.14126.
37. Rajilic-Stojanovic, M., Jonkers, D.M., Salonen, A., Hanevik, K., Raes, J., Jalanka, J., Penders, J., Intestinal microbiota and diet in IBS: Causes, consequences, or epiphenomena?. The American Journal of Gastroenterology 110:2 (2015), 278–287, 10.1038/ajg.2014.427.
38. Rashid, M.U., Weintraub, A., Nord, C.E., Development of antimicrobial resistance in the normal anaerobic microbiota during one year after administration of clindamycin or ciprofloxacin. Anaerobe 31 (2015), 72–77, 10.1016/j.anaerobe.2014.10.004.
39. Simren, M., Barbara, G., Flint, H.J., Spiegel, B.M., Spiller, R.C., Vanner, S., Zoetendal, E.G., Intestinal microbiota in functional bowel disorders: A Rome foundation report. Gut 62:1 (2013), 159–176, 10.1136/gutjnl-2012-302167.
40. Spiegel, B.M., Questioning the bacterial overgrowth hypothesis of irritable bowel syndrome: An epidemiologic and evolutionary perspective. Clinical Gastroenterology and Hepatology 9:6 (2011), 461–469, 10.1016/j.cgh.2011.02.030 quiz e459.
41. Spiller, R., Garsed, K., Postinfectious irritable bowel syndrome. Gastroenterology 136:6 (2009), 1979–1988, 10.1053/j.gastro.2009.02.074.
42. Sudo, N., Chida, Y., Aiba, Y., Sonoda, J., Oyama, N., Yu, X.N., Koga, Y., Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice. The Journal of Physiology 558:Pt. 1 (2004), 263–275, 10.1113/jphysiol.2004.063388.
43. Tana, C., Umesaki, Y., Imaoka, A., Handa, T., Kanazawa, M., Fukudo, S., Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome. Neurogastroenterology and Motility 22:5 (2010), 512–519, 10.1111/j.1365-2982.2009.01427.x e114–515.
44. Uusijarvi, A., Bergstrom, A., Simren, M., Ludvigsson, J.F., Kull, I., Wickman, M., Olen, O., Use of antibiotics in infancy and childhood and risk of recurrent abdominal pain—A Swedish birth cohort study. Neurogastroenterology and Motility 26:6 (2014), 841–850, 10.1111/nmo.12340.
45. Varghese, A.K., Verdu, E.F., Bercik, P., Khan, W.I., Blennerhassett, P.A., Szechtman, H., Collins, S.M., Antidepressants attenuate increased susceptibility to colitis in a murine model of depression. Gastroenterology 130:6 (2006), 1743–1753, 10.1053/j.gastro.2006.02.007.
46. Verdu, E.F., Bercik, P., Verma-Gandhu, M., Huang, X.X., Blennerhassett, P., Jackson, W., Collins, S.M., Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice. Gut 55:2 (2006), 182–190, 10.1136/gut.2005.066100.
47. Villani, A.C., Lemire, M., Thabane, M., Belisle, A., Geneau, G., Garg, A.X., Marshall, J.K., Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis. Gastroenterology 138:4 (2010), 1502–1513, 10.1053/j.gastro.2009.12.049.
48. Zheng, P., Zeng, B., Zhou, C., Liu, M., Fang, Z., Xu, X., Xie, P., Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism. Molecular Psychiatry 21:6 (2016), 786–796, 10.1038/mp.2016.44.
49. Zoetendal, E.G., Raes, J., van den Bogert, B., Arumugam, M., Booijink, C.C., Troost, F.J., Kleerebezem, M., The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates. The ISME Journal 6:7 (2012), 1415–1426, 10.1038/ismej.2011.212.