메뉴 건너뛰기




Volumn 7, Issue OCT, 2016, Pages

Interactions between obesity status and dietary intake of monounsaturated and polyunsaturated oils on human gut microbiome profiles in the canola oil multicenter intervention trial (COMIT)

Author keywords

Blended oil; BMI; Gut microbiota; Monounsaturated fatty acid (MUFA); Polyunsaturated fatty acid (PUFA)

Indexed keywords

CANOLA OIL; CORN OIL; DHA ENRICHED HIGH OLEIC CANOLA OIL; HIGH OLEIC CANOLA OIL; LINSEED OIL; LIPID; MONOUNSATURATED FATTY ACID; OIL; POLYUNSATURATED FATTY ACID; SAFFLOWER OIL; UNCLASSIFIED DRUG;

EID: 84996931176     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2016.01612     Document Type: Article
Times cited : (76)

References (43)
  • 1
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome-a new worldwide definition
    • Alberti, K. G., Zimmet, P., and Shaw, J. (2005). The metabolic syndrome-a new worldwide definition. Lancet 366, 1059-1062. doi: 10.1016/S0140-6736(05)67402-8
    • (2005) Lancet , vol.366 , pp. 1059-1062
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 2
    • 80055098498 scopus 로고    scopus 로고
    • Dietary long-chain n-3 PUFA, gut microbiota and fat mass in early postnatal piglet development-exploring a potential interplay
    • Andersen, A. D., Molbak, L., Thymann, T., Michaelsen, K. F., and Lauritzen, L. (2011). Dietary long-chain n-3 PUFA, gut microbiota and fat mass in early postnatal piglet development-exploring a potential interplay. Prostaglandins Leukot. Essent. Fatty Acids 85, 345-351. doi: 10.1016/j.plefa.2011.08.004
    • (2011) Prostaglandins Leukot. Essent. Fatty Acids , vol.85 , pp. 345-351
    • Andersen, A.D.1    Molbak, L.2    Thymann, T.3    Michaelsen, K.F.4    Lauritzen, L.5
  • 4
    • 33846542071 scopus 로고    scopus 로고
    • Mechanisms underlying the resistance to diet-induced obesity in germ-free mice
    • Bäckhed, F., Manchester, J. K., Semenkovich, C. F., and Gordon, J. I. (2007). Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc. Natl. Acad. Sci. U.S.A. 104, 979-984. doi: 10.1073/pnas.0605374104
    • (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 979-984
    • Bäckhed, F.1    Manchester, J.K.2    Semenkovich, C.F.3    Gordon, J.I.4
  • 5
    • 67349262977 scopus 로고    scopus 로고
    • Metabolic fate of saturated and monounsaturated dietary fats: the Mediterranean diet revisited from epidemiological evidence to cellular mechanisms
    • Bergouignan, A., Momken, I., Schoeller, D. A., Simon, C., and Blanc, S. (2009). Metabolic fate of saturated and monounsaturated dietary fats: the Mediterranean diet revisited from epidemiological evidence to cellular mechanisms. Prog. Lipid Res. 48, 128-147. doi: 10.1016/j.plipres.2009.02.004
    • (2009) Prog. Lipid Res , vol.48 , pp. 128-147
    • Bergouignan, A.1    Momken, I.2    Schoeller, D.A.3    Simon, C.4    Blanc, S.5
  • 6
    • 84884573630 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii supernatant improves intestinal barrier function in mice DSS colitis
    • Carlsson, A. H., Yakymenko, O., Olivier, I., Hakansson, F., Postma, E., Keita, A. V., et al. (2013). Faecalibacterium prausnitzii supernatant improves intestinal barrier function in mice DSS colitis. Scand. J. Gastroenterol. 48, 1136-1144. doi: 10.3109/00365521.2013.828773
    • (2013) Scand. J. Gastroenterol , vol.48 , pp. 1136-1144
    • Carlsson, A.H.1    Yakymenko, O.2    Olivier, I.3    Hakansson, F.4    Postma, E.5    Keita, A.V.6
  • 7
    • 32944469172 scopus 로고    scopus 로고
    • On resemblance measures for ecological studies, including taxonomic dissimilarities and a zero-adjusted Bray-Curtis coefficient for denuded assemblages
    • Clarke, K. R., Somerfiled, P. J., and Chapman, M. G. (2006). On resemblance measures for ecological studies, including taxonomic dissimilarities and a zero-adjusted Bray-Curtis coefficient for denuded assemblages. J. Exp. Mar. Biol. Ecol. 330, 55-80. doi: 10.1016/j.jembe.2005.12.017
    • (2006) J. Exp. Mar. Biol. Ecol , vol.330 , pp. 55-80
    • Clarke, K.R.1    Somerfiled, P.J.2    Chapman, M.G.3
  • 8
    • 80055045344 scopus 로고    scopus 로고
    • Obesity and the gut microbiota: does up-regulating colonic fermentation protect against obesity and metabolic disease?
    • Conterno, L., Fava, F., Viola, R., and Tuohy, K. M. (2011). Obesity and the gut microbiota: does up-regulating colonic fermentation protect against obesity and metabolic disease? Genes Nutr. 6, 241-260. doi: 10.1007/s12263-011-0230-1
    • (2011) Genes Nutr , vol.6 , pp. 241-260
    • Conterno, L.1    Fava, F.2    Viola, R.3    Tuohy, K.M.4
  • 9
    • 84892828465 scopus 로고    scopus 로고
    • Diet rapidly and reproducibly alters the human gut microbiome
    • David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., et al. (2014). Diet rapidly and reproducibly alters the human gut microbiome. Nature 505, 559-563. doi: 10.1038/nature12820
    • (2014) Nature , vol.505 , pp. 559-563
    • David, L.A.1    Maurice, C.F.2    Carmody, R.N.3    Gootenberg, D.B.4    Button, J.E.5    Wolfe, B.E.6
  • 10
    • 77957075815 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    • De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., et al. (2010). Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc. Natl. Acad. Sci. U.S.A. 107, 14691-14696. doi: 10.1073/pnas.1005963107
    • (2010) Proc. Natl. Acad. Sci. U.S.A , vol.107 , pp. 14691-14696
    • De Filippo, C.1    Cavalieri, D.2    Di Paola, M.3    Ramazzotti, M.4    Poullet, J.B.5    Massart, S.6
  • 11
    • 84865726183 scopus 로고    scopus 로고
    • Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine
    • de Wit, N., Derrien, M., Bosch-Vermeulen, H., Oosterink, E., Keshtkar, S., Duval, C., et al. (2012). Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 303, G589-G599. doi: 10.1152/ajpgi.00488.2011
    • (2012) Am. J. Physiol. Gastrointest. Liver Physiol , vol.303 , pp. G589-G599
    • de Wit, N.1    Derrien, M.2    Bosch-Vermeulen, H.3    Oosterink, E.4    Keshtkar, S.5    Duval, C.6
  • 12
    • 49549107771 scopus 로고    scopus 로고
    • Evaluation of the bacterial diversity in the feces of cattle using 16S rDNA bacterial tag-encoded FLX amplicon pyrosequencing (bTEFAP)
    • Dowd, S. E., Callaway, T. R., Wolcott, R. D., Sun, Y., Mckeehan, T., Hagevoort, R. G., et al. (2008). Evaluation of the bacterial diversity in the feces of cattle using 16S rDNA bacterial tag-encoded FLX amplicon pyrosequencing (bTEFAP). BMC Microbiol. 8:125. doi: 10.1186/1471-2180-8-125
    • (2008) BMC Microbiol , vol.8 , pp. 125
    • Dowd, S.E.1    Callaway, T.R.2    Wolcott, R.D.3    Sun, Y.4    Mckeehan, T.5    Hagevoort, R.G.6
  • 13
    • 0037203479 scopus 로고    scopus 로고
    • Diet composition and the metabolic syndrome: what is the optimal fat intake?
    • Grundy, S. M., Abate, N., and Chandalia, M. (2002). Diet composition and the metabolic syndrome: what is the optimal fat intake? Am. J. Med. 113(Suppl. 9B), 25S-29S. doi: 10.1016/S0002-9343(01)00988-3
    • (2002) Am. J. Med , vol.113 , pp. 25S-29S
    • Grundy, S.M.1    Abate, N.2    Chandalia, M.3
  • 14
    • 34748886657 scopus 로고    scopus 로고
    • PAST: paleontological statistics software package for education and data analysis
    • Hammer,Ø., Harper, D. A., and Ryan, P. D. (2001). PAST: paleontological statistics software package for education and data analysis. Palaeontol. Electronica 4, 1-9.
    • (2001) Palaeontol. Electronica , vol.4 , pp. 1-9
    • Hammer, Ø.1    Harper, D.A.2    Ryan, P.D.3
  • 15
    • 84856179128 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other lipids: a review
    • Jacobson, T. A., Glickstein, S. B., Rowe, J. D., and Soni, P. N. (2012). Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other lipids: a review. J. Clin. Lipidol. 6, 5-18. doi: 10.1016/j.jacl.2011.10.018
    • (2012) J. Clin. Lipidol , vol.6 , pp. 5-18
    • Jacobson, T.A.1    Glickstein, S.B.2    Rowe, J.D.3    Soni, P.N.4
  • 16
    • 84903546754 scopus 로고    scopus 로고
    • DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiovascular disease risk in the canola oil multicenter randomized controlled trial
    • Jones, P. J., Senanayake, V. K., Pu, S., Jenkins, D. J., Connelly, P. W., Lamarche, B., et al. (2014). DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiovascular disease risk in the canola oil multicenter randomized controlled trial. Am. J. Clin. Nutr. 100, 88-97. doi: 10.3945/ajcn.113.081133
    • (2014) Am. J. Clin. Nutr , vol.100 , pp. 88-97
    • Jones, P.J.1    Senanayake, V.K.2    Pu, S.3    Jenkins, D.J.4    Connelly, P.W.5    Lamarche, B.6
  • 17
    • 70449457268 scopus 로고    scopus 로고
    • Rumen microbiome composition determined using two nutritional models of subacute ruminal acidosis
    • Khafipour, E., Li, S., Plaizier, J. C., and Krause, D. O. (2009). Rumen microbiome composition determined using two nutritional models of subacute ruminal acidosis. Appl. Environ. Microbiol. 75, 7115-7124. doi: 10.1128/AEM.00739-09
    • (2009) Appl. Environ. Microbiol , vol.75 , pp. 7115-7124
    • Khafipour, E.1    Li, S.2    Plaizier, J.C.3    Krause, D.O.4
  • 18
    • 84879685871 scopus 로고    scopus 로고
    • Fat to treat fat: emerging relationship between dietary PUFA, endocannabinoids, and obesity
    • Kim, J., Li, Y., and Watkins, B. A. (2013). Fat to treat fat: emerging relationship between dietary PUFA, endocannabinoids, and obesity. Prostaglandins Other Lipid Mediat. 10, 32-41. doi: 10.1016/j.prostaglandins.2012.11.005
    • (2013) Prostaglandins Other Lipid Mediat , vol.10 , pp. 32-41
    • Kim, J.1    Li, Y.2    Watkins, B.A.3
  • 19
    • 84997000083 scopus 로고    scopus 로고
    • The fecal environment, the gut
    • eds M. Sadowsky and R. Whitman (Washington, DC: ASM Press)
    • Krause, D. O., and Khafipour, E. (2011). "The fecal environment, the gut," in The Fecal Bacteria, eds M. Sadowsky and R. Whitman (Washington, DC: ASM Press), 1-21. doi: 10.1128/9781555816865.ch1
    • (2011) The Fecal Bacteria , pp. 1-21
    • Krause, D.O.1    Khafipour, E.2
  • 20
    • 74249119678 scopus 로고    scopus 로고
    • Obesity and the human microbiome
    • Ley, R. E. (2010). Obesity and the human microbiome. Curr. Opin. Gastroenterol. 26, 5-11. doi: 10.1097/MOG.0b013e328333d751
    • (2010) Curr. Opin. Gastroenterol , vol.26 , pp. 5-11
    • Ley, R.E.1
  • 22
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley, R. E., Turnbaugh, P. J., Klein, S., and Gordon, J. I. (2006). Microbial ecology: human gut microbes associated with obesity. Nature 444, 1022-1023. doi: 10.1038/4441022a
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 23
    • 84871319656 scopus 로고    scopus 로고
    • Pyrosequencing reveals the influence of organic and conventional farming systems on bacterial communities
    • Li, R., Khafipour, E., Krause, D. O., Entz, M. H., De Kievit, T. R., and Fernando, W. G. (2012). Pyrosequencing reveals the influence of organic and conventional farming systems on bacterial communities. PLoS ONE 7:e51897. doi: 10.1371/journal.pone.0051897
    • (2012) PLoS ONE , vol.7
    • Li, R.1    Khafipour, E.2    Krause, D.O.3    Entz, M.H.4    De Kievit, T.R.5    Fernando, W.G.6
  • 24
    • 84861885563 scopus 로고    scopus 로고
    • Gut bacteria profiles of Mus musculus at the phylum and family levels are influenced by saturation of dietary fatty acids
    • Liu, T., Hougen, H., Vollmer, A. C., and Hiebert, S. M. (2012). Gut bacteria profiles of Mus musculus at the phylum and family levels are influenced by saturation of dietary fatty acids. Anaerobe 18, 331-337. doi: 10.1016/j.anaerobe.2012.02.004
    • (2012) Anaerobe , vol.18 , pp. 331-337
    • Liu, T.1    Hougen, H.2    Vollmer, A.C.3    Hiebert, S.M.4
  • 25
    • 20444381246 scopus 로고    scopus 로고
    • Regulation of adipocyte differentiation and function by polyunsaturated fatty acids
    • Madsen, L., Petersen, R. K., and Kristiansen, K. (2005). Regulation of adipocyte differentiation and function by polyunsaturated fatty acids. Biochim. Biophys. Acta 1740, 266-286. doi: 10.1016/j.bbadis.2005.03.001
    • (2005) Biochim. Biophys. Acta , vol.1740 , pp. 266-286
    • Madsen, L.1    Petersen, R.K.2    Kristiansen, K.3
  • 26
    • 65249102362 scopus 로고    scopus 로고
    • A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease
    • Mente, A., De Koning, L., Shannon, H. S., and Anand, S. S. (2009). A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease. Arch. Intern. Med. 169, 659-669. doi: 10.1001/archinternmed.2009.38
    • (2009) Arch. Intern. Med , vol.169 , pp. 659-669
    • Mente, A.1    De Koning, L.2    Shannon, H.S.3    Anand, S.S.4
  • 27
    • 84880171148 scopus 로고    scopus 로고
    • Changes in gut microbiota due to supplemented fatty acids in diet-induced obese mice
    • Mujico, J. R., Baccan, G. C., Gheorghe, A., Diaz, L. E., and Marcos, A. (2013). Changes in gut microbiota due to supplemented fatty acids in diet-induced obese mice. Br. J. Nutr. 110, 711-720. doi: 10.1017/S0007114512005612
    • (2013) Br. J. Nutr , vol.110 , pp. 711-720
    • Mujico, J.R.1    Baccan, G.C.2    Gheorghe, A.3    Diaz, L.E.4    Marcos, A.5
  • 28
    • 78649887273 scopus 로고    scopus 로고
    • Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models
    • Murphy, E., Cotter, P., Healy, S., Marques, T., O'sullivan, O., Fouhy, F., et al. (2010). Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models. Gut 59, 1635-1642. doi: 10.1136/gut.2010.215665
    • (2010) Gut , vol.59 , pp. 1635-1642
    • Murphy, E.1    Cotter, P.2    Healy, S.3    Marques, T.4    O'sullivan, O.5    Fouhy, F.6
  • 29
    • 84900332803 scopus 로고    scopus 로고
    • Effects of parental omega-3 Fatty Acid intake on offspring microbiome and immunity
    • Myles, I. A., Pincus, N. B., Fontecilla, N. M., and Datta, S. K. (2014). Effects of parental omega-3 Fatty Acid intake on offspring microbiome and immunity. PLoS ONE 9:e87181. doi: 10.1371/journal.pone.0087181
    • (2014) PLoS ONE , vol.9
    • Myles, I.A.1    Pincus, N.B.2    Fontecilla, N.M.3    Datta, S.K.4
  • 31
    • 37549027613 scopus 로고    scopus 로고
    • SILVA: a comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB
    • Pruesse, E., Quast, C., Knittel, K., Fuchs, B. M., Ludwig, W., Peplies, J., et al. (2007). SILVA: a comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB. Nucleic Acids Res. 35, 7188-7196. doi: 10.1093/nar/gkm864
    • (2007) Nucleic Acids Res , vol.35 , pp. 7188-7196
    • Pruesse, E.1    Quast, C.2    Knittel, K.3    Fuchs, B.M.4    Ludwig, W.5    Peplies, J.6
  • 33
    • 84873342775 scopus 로고    scopus 로고
    • Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
    • Sayin, S. I., Wahlstrom, A., Felin, J., Jantti, S., Marschall, H. U., Bamberg, K., et al. (2013). Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab. 17, 225-235. doi: 10.1016/j.cmet.2013.01.003
    • (2013) Cell Metab , vol.17 , pp. 225-235
    • Sayin, S.I.1    Wahlstrom, A.2    Felin, J.3    Jantti, S.4    Marschall, H.U.5    Bamberg, K.6
  • 34
    • 72949107142 scopus 로고    scopus 로고
    • Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities
    • Schloss, P. D., Westcott, S. L., Ryabin, T., Hall, J. R., Hartmann, M., Hollister, E. B., et al. (2009). Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl. Environ. Microbiol. 75, 7537-7541. doi: 10.1128/AEM.01541-09
    • (2009) Appl. Environ. Microbiol , vol.75 , pp. 7537-7541
    • Schloss, P.D.1    Westcott, S.L.2    Ryabin, T.3    Hall, J.R.4    Hartmann, M.5    Hollister, E.B.6
  • 35
    • 73949137604 scopus 로고    scopus 로고
    • Microbiota and SCFA in lean and overweight healthy subjects
    • Schwiertz, A., Taras, D., Schäfer, K., Beijer, S., Bos, N. A., Donus, C., et al. (2010). Microbiota and SCFA in lean and overweight healthy subjects. Obesity 18, 190-195. doi: 10.1038/oby.2009.167
    • (2010) Obesity , vol.18 , pp. 190-195
    • Schwiertz, A.1    Taras, D.2    Schäfer, K.3    Beijer, S.4    Bos, N.A.5    Donus, C.6
  • 36
    • 84900344483 scopus 로고    scopus 로고
    • Plasma fatty acid changes following consumption of dietary oils containing n-3, n-6, and n-9 fatty acids at different proportions: preliminary findings of the Canola Oil Multicenter Intervention Trial (COMIT)
    • Senanayake, V. K., Pu, S., Jenkins, D. A., Lamarche, B., Kris-Etherton, P. M., West, S. G., et al. (2014). Plasma fatty acid changes following consumption of dietary oils containing n-3, n-6, and n-9 fatty acids at different proportions: preliminary findings of the Canola Oil Multicenter Intervention Trial (COMIT). Trials 15:136. doi: 10.1186/1745-6215-15-136
    • (2014) Trials , vol.15 , pp. 136
    • Senanayake, V.K.1    Pu, S.2    Jenkins, D.A.3    Lamarche, B.4    Kris-Etherton, P.M.5    West, S.G.6
  • 37
    • 34250375140 scopus 로고    scopus 로고
    • Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease
    • Sepehri, S., Kotlowski, R., Bernstein, C. N., and Krause, D. O. (2007). Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease. Inflamm. Bowel Dis. 13, 675-683. doi: 10.1002/ibd.20101
    • (2007) Inflamm. Bowel Dis , vol.13 , pp. 675-683
    • Sepehri, S.1    Kotlowski, R.2    Bernstein, C.N.3    Krause, D.O.4
  • 38
    • 2142820810 scopus 로고    scopus 로고
    • LDL cholesterol-raising effect of low-dose docosahexaenoic acid in middle-aged men and women
    • Theobald, H. E., Chowienczyk, P. J., Whittall, R., Humphries, S. E., and Sanders, T. A. (2004). LDL cholesterol-raising effect of low-dose docosahexaenoic acid in middle-aged men and women. Am. J. Clin. Nutr. 79, 558-563.
    • (2004) Am. J. Clin. Nutr , vol.79 , pp. 558-563
    • Theobald, H.E.1    Chowienczyk, P.J.2    Whittall, R.3    Humphries, S.E.4    Sanders, T.A.5
  • 39
    • 41849127118 scopus 로고    scopus 로고
    • Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome
    • Turnbaugh, P. J., Backhed, F., Fulton, L., and Gordon, J. I. (2008). Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 3, 213-223. doi: 10.1016/j.chom.2008.02.015
    • (2008) Cell Host Microbe , vol.3 , pp. 213-223
    • Turnbaugh, P.J.1    Backhed, F.2    Fulton, L.3    Gordon, J.I.4
  • 41
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice
    • Turnbaugh, P. J., Ridaura, V. K., Faith, J. J., Rey, F. E., Knight, R., and Gordon, J. I. (2009b). The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci. Transl. Med. 1:6ra14. doi: 10.1126/scitranslmed.3000322
    • (2009) Sci. Transl. Med , vol.1
    • Turnbaugh, P.J.1    Ridaura, V.K.2    Faith, J.J.3    Rey, F.E.4    Knight, R.5    Gordon, J.I.6
  • 43
    • 84866040724 scopus 로고    scopus 로고
    • Is bile acid a determinant of the gut microbiota on a high-fat diet?
    • Yokota, A., Fukiya, S., Islam, K. B., Ooka, T., Ogura, Y., Hayashi, T., et al. (2012). Is bile acid a determinant of the gut microbiota on a high-fat diet? Gut Microbes 3, 455-459. doi: 10.4161/gmic.21216
    • (2012) Gut Microbes , vol.3 , pp. 455-459
    • Yokota, A.1    Fukiya, S.2    Islam, K.B.3    Ooka, T.4    Ogura, Y.5    Hayashi, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.